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The map label for this gene is thiL [H]

Identifier: 119774158

GI number: 119774158

Start: 1234973

End: 1235974

Strand: Direct

Name: thiL [H]

Synonym: Sama_1021

Alternate gene names: 119774158

Gene position: 1234973-1235974 (Clockwise)

Preceding gene: 119774157

Following gene: 119774159

Centisome position: 28.68

GC content: 56.69

Gene sequence:

>1002_bases
ATGGGTCGGCGGGCCGACATCAAGGCCGACGCCGGAATGACAGTGAAAGAATTCCAACTTATCGATCAGTATTTCTGTGG
CCGTGGCCCGGTGCGTCGGGATGTTAAACACGGTATTGGCGACGACTGTGCCCTGGTTCAACCGGCTGAGCACAAGCAGA
TTGCCATCTCCTGTGACACCCTGATAGAAGGGGTGCATTTCTTCAACGATATGCCTGCCTGGGCACTGGGTTACAAGGCG
CTTGCCGTCAACCTGTCAGACTTGGCCGCCATGGGCGCCGAGCCAGCCTGGTTTACTCTTGGCCTTAGTTTACCATCGGT
GGATGAAAGCTGGCTCGCTGCCTTTAGCGAAGGCCTGTTTGAGGCCGCCGAATATTATGGTATCGCGCTGATTGGCGGCG
ATACCACCCAAAGCCCTGTGAAGGTCATAGCCGTTACCATCAATGGTCAGGTGCCCGAAGGCAAGGCGCTCACACGCTAC
GGTGCCCGTAGCGGCGACTGGATTTACGTTACTGGCTCGTTGGGAGACTCTGCGTTGGGGCTGGATATCCTCAGAGGACG
TCAGCAAAGTCGCCCGGAGCACAGTGAGTACCTGATTGAGCGTCATTACCGACCTACACCAAGGGTACTTGCTGGCCAAT
CTTTGCGAGGTCTGGCATCCAGTGCCATCGACCTGTCCGATGGTTTGATGTCTGATCTTGGCCATGTGCTGAAGGCGTCC
AATGTGGGTGCCTACATTGACGTGGAAAAGTTACCCCTGTCACAGGCGATGAAGGACTCGGTGCCGCTTGAGCAGGCGCT
TGGGTATGCGCTCACCGGTGGAGAGGACTACGAGCTGCTCTTTACCGTGCCAGAGGCGCAACGTGGTGCGCTGGAAATTG
CGCTGGCCAATGCCGGGGTGAAGTTTTTCCGCATCGGGCAAATCACGGCGGGCAGCACCCTCAAGCTGACCCATAACGGT
GAGCCTTTCACACCGATGAACAAAGGTTTTGAGCATTTCTGA

Upstream 100 bases:

>100_bases
CAAATTCGTTAACGGTATTTTGGATAAGCTGGTTGCACGCAACTAAATGACAGACGGTGCCTGAGGGTGCCGTTTTTCAT
TTTCCGGTGTTCATTTTTCA

Downstream 100 bases:

>100_bases
TGGGTTGGCGCAGTCAAGATGAGGCGCTGTCGCGTCTGTCGTTAAAAAATCCCTGGCATTTTCTTGCCCTTGGCTTTGGC
AGTGGTTTGGCCAAAAAGGC

Product: thiamine-phosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MGRRADIKADAGMTVKEFQLIDQYFCGRGPVRRDVKHGIGDDCALVQPAEHKQIAISCDTLIEGVHFFNDMPAWALGYKA
LAVNLSDLAAMGAEPAWFTLGLSLPSVDESWLAAFSEGLFEAAEYYGIALIGGDTTQSPVKVIAVTINGQVPEGKALTRY
GARSGDWIYVTGSLGDSALGLDILRGRQQSRPEHSEYLIERHYRPTPRVLAGQSLRGLASSAIDLSDGLMSDLGHVLKAS
NVGAYIDVEKLPLSQAMKDSVPLEQALGYALTGGEDYELLFTVPEAQRGALEIALANAGVKFFRIGQITAGSTLKLTHNG
EPFTPMNKGFEHF

Sequences:

>Translated_333_residues
MGRRADIKADAGMTVKEFQLIDQYFCGRGPVRRDVKHGIGDDCALVQPAEHKQIAISCDTLIEGVHFFNDMPAWALGYKA
LAVNLSDLAAMGAEPAWFTLGLSLPSVDESWLAAFSEGLFEAAEYYGIALIGGDTTQSPVKVIAVTINGQVPEGKALTRY
GARSGDWIYVTGSLGDSALGLDILRGRQQSRPEHSEYLIERHYRPTPRVLAGQSLRGLASSAIDLSDGLMSDLGHVLKAS
NVGAYIDVEKLPLSQAMKDSVPLEQALGYALTGGEDYELLFTVPEAQRGALEIALANAGVKFFRIGQITAGSTLKLTHNG
EPFTPMNKGFEHF
>Mature_332_residues
GRRADIKADAGMTVKEFQLIDQYFCGRGPVRRDVKHGIGDDCALVQPAEHKQIAISCDTLIEGVHFFNDMPAWALGYKAL
AVNLSDLAAMGAEPAWFTLGLSLPSVDESWLAAFSEGLFEAAEYYGIALIGGDTTQSPVKVIAVTINGQVPEGKALTRYG
ARSGDWIYVTGSLGDSALGLDILRGRQQSRPEHSEYLIERHYRPTPRVLAGQSLRGLASSAIDLSDGLMSDLGHVLKASN
VGAYIDVEKLPLSQAMKDSVPLEQALGYALTGGEDYELLFTVPEAQRGALEIALANAGVKFFRIGQITAGSTLKLTHNGE
PFTPMNKGFEHF

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=323, Percent_Identity=57.2755417956656, Blast_Score=350, Evalue=6e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35903; Mature: 35772

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRRADIKADAGMTVKEFQLIDQYFCGRGPVRRDVKHGIGDDCALVQPAEHKQIAISCDT
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCCCEEEEEHHH
LIEGVHFFNDMPAWALGYKALAVNLSDLAAMGAEPAWFTLGLSLPSVDESWLAAFSEGLF
HHHHHHHHCCCCHHHHCHHHEEEEHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
EAAEYYGIALIGGDTTQSPVKVIAVTINGQVPEGKALTRYGARSGDWIYVTGSLGDSALG
HHHHHEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHCCCCCCCEEEEECCCCCCHHH
LDILRGRQQSRPEHSEYLIERHYRPTPRVLAGQSLRGLASSAIDLSDGLMSDLGHVLKAS
HHHHHCCCCCCCCHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHC
NVGAYIDVEKLPLSQAMKDSVPLEQALGYALTGGEDYELLFTVPEAQRGALEIALANAGV
CCCEEEEECCCCHHHHHHCCCCHHHHCCEEEECCCCEEEEEECCCCCCCEEEEEEECCCE
KFFRIGQITAGSTLKLTHNGEPFTPMNKGFEHF
EEEEEEEEECCCEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
GRRADIKADAGMTVKEFQLIDQYFCGRGPVRRDVKHGIGDDCALVQPAEHKQIAISCDT
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEECCCCCCEEEEEHHH
LIEGVHFFNDMPAWALGYKALAVNLSDLAAMGAEPAWFTLGLSLPSVDESWLAAFSEGLF
HHHHHHHHCCCCHHHHCHHHEEEEHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHHH
EAAEYYGIALIGGDTTQSPVKVIAVTINGQVPEGKALTRYGARSGDWIYVTGSLGDSALG
HHHHHEEEEEECCCCCCCCEEEEEEEECCCCCCCCHHHHCCCCCCCEEEEECCCCCCHHH
LDILRGRQQSRPEHSEYLIERHYRPTPRVLAGQSLRGLASSAIDLSDGLMSDLGHVLKAS
HHHHHCCCCCCCCHHHHHHHHCCCCCCCHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHC
NVGAYIDVEKLPLSQAMKDSVPLEQALGYALTGGEDYELLFTVPEAQRGALEIALANAGV
CCCEEEEECCCCHHHHHHCCCCHHHHCCEEEECCCCEEEEEECCCCCCCEEEEEEECCCE
KFFRIGQITAGSTLKLTHNGEPFTPMNKGFEHF
EEEEEEEEECCCEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]