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The map label for this gene is hlyB [H]

Identifier: 119774079

GI number: 119774079

Start: 1139226

End: 1140713

Strand: Direct

Name: hlyB [H]

Synonym: Sama_0942

Alternate gene names: 119774079

Gene position: 1139226-1140713 (Clockwise)

Preceding gene: 119774078

Following gene: 119774080

Centisome position: 26.46

GC content: 56.05

Gene sequence:

>1488_bases
ATGAATAATAATCTGGCACTTAAGGTGCAGATTGGCCTGGCATTGGCGCTGTCAGGCTTGATGGTGTTGCTGTTTGGTGC
GACCTTTTTGTTTGAAAAGCAAAAGCTTGAACAGGCCTTTGCCGAATATGAAAAAGATACCCTCGCCAGTCTGGCAGTGA
CCATGGCTCAGCCAGTGTTTACCTATGATTTTGAACAGATAGAAGCAATTTTGTCGGTGACCCTGGAGCAGGAGCAAATC
GCCGCGCTCAAGGTGTTCGATCATCGCGGTAAGCCCATGGCCAGTGTTGGCAGCAATACCGGCGAAGATGCGGGTCTTGA
GCAAAAGAGCATTAGCTTTAGCGACAACGGCAAACCCACCGGCAAGATGGAGGTGACCTTTACCCGGGCGCCCATTGAGG
CGAGACTCAGCTCCTTGTTGCTTGGGCTACTGGCCCAGGGCGCACTGATTTTGTTGCTGAGTATGGTGGTGATCGTCATT
ATTCTCAAAAAGTTGGTGATTACTCCCCTTGCTCACGTCGTTTCGGCCATGGAGGATGTAGCCAGCGGTGATGGCGACCT
GACCCGTCGGCTGCCGGTGGAAAGTCAGGATGAGATTGGCCGTCTGGCATCGGCTTTTAATGCCTTTATTGAACAAATTC
ATGCCACCGTAACCAAGGTGCAGGAAACCGCTGCCCAGCTGATTGAAGGGGCGGGCACCCTGGGAAGCCTCAGCGGCGCC
AATAATCTGAGGGTGCAGGAGCAGCGTCAGGAGACCGAAGCGGCGGTGACTGCGGTCAGCCAGCTGTCGGCCAGTGCTGC
CGAGGTGGCTGGTAATGCCCTGCGTACCTCCGAAGCGGCGGCCGAGGCCGATGCCCAGGTGGATGAGAGTCAGCGCCGCT
TCGACCAGAGTCTGGGGCTGACCCGCCAGCTGGTGGATGAGCTCAGCCGCTGCGCCATATCCGTACAGCAGCTGCAGCAG
GAAACTCAAAAGATTGATGAAGTGGTAGTGGTGATTAACAGCATTGCCGAGCAGACCAATCTGCTGGCACTGAATGCCGC
CATTGAGGCCGCCCGGGCGGGAGAGCAGGGCAGGGGCTTTGCTGTGGTGGCCGATGAAGTGCGCACCCTGGCAAGCCGCA
CCCAGCAAGCCACCGGCGAAATTCAAAAGATGATCCAGCAGGTGCAAACCCGGGTGAATGATACCGTTACCGTGATGGGG
GCCAGTCAGCAGCTGTCGGATAAGTCGTTGTCGCAGGCCGAGGAAATCAAATCCATGCTTGCCAGCGTTACCCGCCTGGT
TTCCAATATCAACGCCATGAATACCGAAGTGGCCCATGCTGCATCAGAGCAAACCAGCGTCACTGAAAATATTTCCAGAA
GTTTGAACGATCTCGCCGGCATCTCAGGTTCGGCCTCAGCAGACAGTGCCTCGTTGGCGCAGTCCGGTGAGCGCCTGTTC
CAACAGGGGGAAAGATTGCGGGCACTTGTAAACTCATTCAGGTTGTAG

Upstream 100 bases:

>100_bases
AACGGGTCATCATCCGCTTGAATACGTCGGATTTGAGCCCACAGACGCCGGTACACCGGCCTGAGTTATGGCTCGATCTG
TTCAGTATGGAGGGGGTGAA

Downstream 100 bases:

>100_bases
CCCTGAAAAAACAGGAAAAATGAGGACAACAATGAAATTTTCCTTAGCCGCATCTGCGATTTTTCTCGCCTTGGGTGTCA
GTGGGTGCTCACAAGCCCCG

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MNNNLALKVQIGLALALSGLMVLLFGATFLFEKQKLEQAFAEYEKDTLASLAVTMAQPVFTYDFEQIEAILSVTLEQEQI
AALKVFDHRGKPMASVGSNTGEDAGLEQKSISFSDNGKPTGKMEVTFTRAPIEARLSSLLLGLLAQGALILLLSMVVIVI
ILKKLVITPLAHVVSAMEDVASGDGDLTRRLPVESQDEIGRLASAFNAFIEQIHATVTKVQETAAQLIEGAGTLGSLSGA
NNLRVQEQRQETEAAVTAVSQLSASAAEVAGNALRTSEAAAEADAQVDESQRRFDQSLGLTRQLVDELSRCAISVQQLQQ
ETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATGEIQKMIQQVQTRVNDTVTVMG
ASQQLSDKSLSQAEEIKSMLASVTRLVSNINAMNTEVAHAASEQTSVTENISRSLNDLAGISGSASADSASLAQSGERLF
QQGERLRALVNSFRL

Sequences:

>Translated_495_residues
MNNNLALKVQIGLALALSGLMVLLFGATFLFEKQKLEQAFAEYEKDTLASLAVTMAQPVFTYDFEQIEAILSVTLEQEQI
AALKVFDHRGKPMASVGSNTGEDAGLEQKSISFSDNGKPTGKMEVTFTRAPIEARLSSLLLGLLAQGALILLLSMVVIVI
ILKKLVITPLAHVVSAMEDVASGDGDLTRRLPVESQDEIGRLASAFNAFIEQIHATVTKVQETAAQLIEGAGTLGSLSGA
NNLRVQEQRQETEAAVTAVSQLSASAAEVAGNALRTSEAAAEADAQVDESQRRFDQSLGLTRQLVDELSRCAISVQQLQQ
ETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATGEIQKMIQQVQTRVNDTVTVMG
ASQQLSDKSLSQAEEIKSMLASVTRLVSNINAMNTEVAHAASEQTSVTENISRSLNDLAGISGSASADSASLAQSGERLF
QQGERLRALVNSFRL
>Mature_495_residues
MNNNLALKVQIGLALALSGLMVLLFGATFLFEKQKLEQAFAEYEKDTLASLAVTMAQPVFTYDFEQIEAILSVTLEQEQI
AALKVFDHRGKPMASVGSNTGEDAGLEQKSISFSDNGKPTGKMEVTFTRAPIEARLSSLLLGLLAQGALILLLSMVVIVI
ILKKLVITPLAHVVSAMEDVASGDGDLTRRLPVESQDEIGRLASAFNAFIEQIHATVTKVQETAAQLIEGAGTLGSLSGA
NNLRVQEQRQETEAAVTAVSQLSASAAEVAGNALRTSEAAAEADAQVDESQRRFDQSLGLTRQLVDELSRCAISVQQLQQ
ETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRTQQATGEIQKMIQQVQTRVNDTVTVMG
ASQQLSDKSLSQAEEIKSMLASVTRLVSNINAMNTEVAHAASEQTSVTENISRSLNDLAGISGSASADSASLAQSGERLF
QQGERLRALVNSFRL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=357, Percent_Identity=31.9327731092437, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1788194, Length=356, Percent_Identity=30.8988764044944, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788195, Length=286, Percent_Identity=34.2657342657343, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI2367378, Length=348, Percent_Identity=29.8850574712644, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1789453, Length=346, Percent_Identity=27.4566473988439, Blast_Score=92, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 52842; Mature: 52842

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNLALKVQIGLALALSGLMVLLFGATFLFEKQKLEQAFAEYEKDTLASLAVTMAQPVF
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYDFEQIEAILSVTLEQEQIAALKVFDHRGKPMASVGSNTGEDAGLEQKSISFSDNGKPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GKMEVTFTRAPIEARLSSLLLGLLAQGALILLLSMVVIVIILKKLVITPLAHVVSAMEDV
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGDGDLTRRLPVESQDEIGRLASAFNAFIEQIHATVTKVQETAAQLIEGAGTLGSLSGA
HCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NNLRVQEQRQETEAAVTAVSQLSASAAEVAGNALRTSEAAAEADAQVDESQRRFDQSLGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCH
TRQLVDELSRCAISVQQLQQETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AVVADEVRTLASRTQQATGEIQKMIQQVQTRVNDTVTVMGASQQLSDKSLSQAEEIKSML
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHH
ASVTRLVSNINAMNTEVAHAASEQTSVTENISRSLNDLAGISGSASADSASLAQSGERLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
QQGERLRALVNSFRL
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MNNNLALKVQIGLALALSGLMVLLFGATFLFEKQKLEQAFAEYEKDTLASLAVTMAQPVF
CCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYDFEQIEAILSVTLEQEQIAALKVFDHRGKPMASVGSNTGEDAGLEQKSISFSDNGKPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCC
GKMEVTFTRAPIEARLSSLLLGLLAQGALILLLSMVVIVIILKKLVITPLAHVVSAMEDV
CEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ASGDGDLTRRLPVESQDEIGRLASAFNAFIEQIHATVTKVQETAAQLIEGAGTLGSLSGA
HCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
NNLRVQEQRQETEAAVTAVSQLSASAAEVAGNALRTSEAAAEADAQVDESQRRFDQSLGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCH
TRQLVDELSRCAISVQQLQQETQKIDEVVVVINSIAEQTNLLALNAAIEAARAGEQGRGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCE
AVVADEVRTLASRTQQATGEIQKMIQQVQTRVNDTVTVMGASQQLSDKSLSQAEEIKSML
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHH
ASVTRLVSNINAMNTEVAHAASEQTSVTENISRSLNDLAGISGSASADSASLAQSGERLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
QQGERLRALVNSFRL
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]