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The map label for this gene is mviN [H]

Identifier: 119774059

GI number: 119774059

Start: 1113812

End: 1115377

Strand: Direct

Name: mviN [H]

Synonym: Sama_0922

Alternate gene names: 119774059

Gene position: 1113812-1115377 (Clockwise)

Preceding gene: 119774057

Following gene: 119774060

Centisome position: 25.87

GC content: 53.0

Gene sequence:

>1566_bases
TTGAGTAAAAAATTACTGAAGTCGGGGTTGGTTGTGAGTGCCATGACCTTCATCTCCCGTGTATTGGGCCTTGTGCGGGA
TATGGTGGTGGCCAACCTGATGGGGGCCGGGGCCAGTGCCGATGTGTTCTTTTTTGCCAATAAAATCCCAAATTTCCTGC
GCAGATTGTTTGCCGAAGGGGCATTTGCTCAGGCTTTTGTGCCTGTGCTGACCGAATATCAGGAAAAGCGCAGCAGCGAA
GAAACCCGTGAACTCATATCCAAAGTCGCGGGTACCCTTGGGGGATTGGTTACCATAGTGACTCTGCTCGGTGTGATTGG
CTCACCGATACTGGCGGCGCTCTTTGGTGGCGGTTGGTTTTTGGACTGGCTCGAAGGCGGCGAAAACGGGGCCAAGTTTG
AACTGGCGGCCCTGATGCTGAAGATCACCTTTCCTTATTTGTGGTTTATCACCTTTACTGCGCTGGCGGGCTCCATTCTC
AATACCCGCGGGCGCTTTGCCGTGTCAGCCTTTACCCCGGTATTTTTGAATATTGCCATTATCGCTTTCGCCCTGTGGCT
GTCACCGCAGCTTGAGCAGCCGGAAATCGGTTTGGCCTGGGGCGTGTTTGCCGGCGGTCTTATTCAGTTTCTGTTCCAAA
TTCCCTTTTTGTACCGCGAGCGTGCCCTGGTTAAGCCCTCCTGGGGCTGGCATCACCCGGGCGTCGTTAAAATCCGTACC
CTGATGATCCCTGCGCTGTTTGGCGTATCTGTATCGCAGATTAACTTGCTGTTCGATACCTTTATTGCCAGCTTCCTGAT
GACGGGTTCCATCAGCTGGCTCTATTACTCGGACCGCCTGCTGGAGTTTCCATTGGGGCTCTTTGGCATTGCCATCGCCA
CAGTAGTGCTTCCTGCTCTGTCGAAAAAGCATGTAAATGATGAAGGTGATGGCTTTGCAAAAACCATGGATTGGGGGGTA
AGGGCGATTTTGCTCCTTGGTATGCCTGCGATGGTAGGGTTGATAGTGCTCGCCAAGCCCATGCTGATGGTGCTCTTTAT
GCGTGGCGCCTTTGATATTTCCGATGTGGAAATGGCGTCTTACAGCTTGATGGCCTACGGTGCTGGCTTGCTTAACTTTA
TGTTGATTAAGGTGTTGGCCCCCGGTTATTACTCCCGTCAGGACACCAAAACTCCGGTGCGTTATGGCATTGTGGCCATG
GTCAGCAATATGGTGTTCAACATCATTTTCGCTGTGCCCTTTGGTTATGTGGGGCTGGCGATTGCCACTTCCTTATCTGC
TTTGCTGAACGCAGCACTGCTTTACCGCGGTTTGCATTTGGCCGGGGTATACAGGTTAACCCTGCCCACGCTGGTGTTTT
TTGGCAAGGTGGCGGCTTCGACCCTCGCTATGGGCGCGCTTCTGTGGTATCTGTTGCCGGTGGTGGATGTATGGTTGGCC
TGGAATATTGTCCATCGGGTCATCGCTCTGGCAGCCTTGATTGTGGGTGGGGCATTTTTGTACGGCACCCTTTTGCTCCT
TTTGGGAATTAAACCCTGGCAGATGAAACGCGCCCGCAAGGGCTGA

Upstream 100 bases:

>100_bases
TGTGGCGCAATTCTACCAGCAAATACTGGCGTATGACAGAGCCGGAAGCGTTTTTTTCCAAGATATCACCCGCATTTTCC
GGTCCTTCCCAGGGGGCAAA

Downstream 100 bases:

>100_bases
TTCTCAGTGTCAGCTGAGATATAATCCGCCAATTTACGTACGCCAGTTGTCAGAACACATGGAATTAATCCGCGGAATTC
ACAATATCTTGCCCGCCCAT

Product: integral membrane protein MviN

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MSKKLLKSGLVVSAMTFISRVLGLVRDMVVANLMGAGASADVFFFANKIPNFLRRLFAEGAFAQAFVPVLTEYQEKRSSE
ETRELISKVAGTLGGLVTIVTLLGVIGSPILAALFGGGWFLDWLEGGENGAKFELAALMLKITFPYLWFITFTALAGSIL
NTRGRFAVSAFTPVFLNIAIIAFALWLSPQLEQPEIGLAWGVFAGGLIQFLFQIPFLYRERALVKPSWGWHHPGVVKIRT
LMIPALFGVSVSQINLLFDTFIASFLMTGSISWLYYSDRLLEFPLGLFGIAIATVVLPALSKKHVNDEGDGFAKTMDWGV
RAILLLGMPAMVGLIVLAKPMLMVLFMRGAFDISDVEMASYSLMAYGAGLLNFMLIKVLAPGYYSRQDTKTPVRYGIVAM
VSNMVFNIIFAVPFGYVGLAIATSLSALLNAALLYRGLHLAGVYRLTLPTLVFFGKVAASTLAMGALLWYLLPVVDVWLA
WNIVHRVIALAALIVGGAFLYGTLLLLLGIKPWQMKRARKG

Sequences:

>Translated_521_residues
MSKKLLKSGLVVSAMTFISRVLGLVRDMVVANLMGAGASADVFFFANKIPNFLRRLFAEGAFAQAFVPVLTEYQEKRSSE
ETRELISKVAGTLGGLVTIVTLLGVIGSPILAALFGGGWFLDWLEGGENGAKFELAALMLKITFPYLWFITFTALAGSIL
NTRGRFAVSAFTPVFLNIAIIAFALWLSPQLEQPEIGLAWGVFAGGLIQFLFQIPFLYRERALVKPSWGWHHPGVVKIRT
LMIPALFGVSVSQINLLFDTFIASFLMTGSISWLYYSDRLLEFPLGLFGIAIATVVLPALSKKHVNDEGDGFAKTMDWGV
RAILLLGMPAMVGLIVLAKPMLMVLFMRGAFDISDVEMASYSLMAYGAGLLNFMLIKVLAPGYYSRQDTKTPVRYGIVAM
VSNMVFNIIFAVPFGYVGLAIATSLSALLNAALLYRGLHLAGVYRLTLPTLVFFGKVAASTLAMGALLWYLLPVVDVWLA
WNIVHRVIALAALIVGGAFLYGTLLLLLGIKPWQMKRARKG
>Mature_520_residues
SKKLLKSGLVVSAMTFISRVLGLVRDMVVANLMGAGASADVFFFANKIPNFLRRLFAEGAFAQAFVPVLTEYQEKRSSEE
TRELISKVAGTLGGLVTIVTLLGVIGSPILAALFGGGWFLDWLEGGENGAKFELAALMLKITFPYLWFITFTALAGSILN
TRGRFAVSAFTPVFLNIAIIAFALWLSPQLEQPEIGLAWGVFAGGLIQFLFQIPFLYRERALVKPSWGWHHPGVVKIRTL
MIPALFGVSVSQINLLFDTFIASFLMTGSISWLYYSDRLLEFPLGLFGIAIATVVLPALSKKHVNDEGDGFAKTMDWGVR
AILLLGMPAMVGLIVLAKPMLMVLFMRGAFDISDVEMASYSLMAYGAGLLNFMLIKVLAPGYYSRQDTKTPVRYGIVAMV
SNMVFNIIFAVPFGYVGLAIATSLSALLNAALLYRGLHLAGVYRLTLPTLVFFGKVAASTLAMGALLWYLLPVVDVWLAW
NIVHRVIALAALIVGGAFLYGTLLLLLGIKPWQMKRARKG

Specific function: Unknown

COG id: COG0728

COG function: function code R; Uncharacterized membrane protein, putative virulence factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mviN family [H]

Homologues:

Organism=Escherichia coli, GI1787309, Length=514, Percent_Identity=40.8560311284047, Blast_Score=390, Evalue=1e-109,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004268 [H]

Pfam domain/function: PF03023 MVIN [H]

EC number: NA

Molecular weight: Translated: 56896; Mature: 56765

Theoretical pI: Translated: 10.23; Mature: 10.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC
>Mature Secondary Structure 
SKKLLKSGLVVSAMTFISRVLGLVRDMVVANLMGAGASADVFFFANKIPNFLRRLFAEG
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
AFAQAFVPVLTEYQEKRSSEETRELISKVAGTLGGLVTIVTLLGVIGSPILAALFGGGWF
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LDWLEGGENGAKFELAALMLKITFPYLWFITFTALAGSILNTRGRFAVSAFTPVFLNIAI
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHH
IAFALWLSPQLEQPEIGLAWGVFAGGLIQFLFQIPFLYRERALVKPSWGWHHPGVVKIRT
HHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH
LMIPALFGVSVSQINLLFDTFIASFLMTGSISWLYYSDRLLEFPLGLFGIAIATVVLPAL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
SKKHVNDEGDGFAKTMDWGVRAILLLGMPAMVGLIVLAKPMLMVLFMRGAFDISDVEMAS
HHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
YSLMAYGAGLLNFMLIKVLAPGYYSRQDTKTPVRYGIVAMVSNMVFNIIFAVPFGYVGLA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IATSLSALLNAALLYRGLHLAGVYRLTLPTLVFFGKVAASTLAMGALLWYLLPVVDVWLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WNIVHRVIALAALIVGGAFLYGTLLLLLGIKPWQMKRARKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9457888; 10952301 [H]