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The map label for this gene is hcr [H]

Identifier: 119774033

GI number: 119774033

Start: 1084460

End: 1085530

Strand: Direct

Name: hcr [H]

Synonym: Sama_0896

Alternate gene names: 119774033

Gene position: 1084460-1085530 (Clockwise)

Preceding gene: 119774032

Following gene: 119774034

Centisome position: 25.18

GC content: 53.97

Gene sequence:

>1071_bases
ATGAGTCAACACCGGGACGCTGCTTTTCTGACAGCCAAATCCTGGCAGGATTTACCTGCTTCAGTGCCTTTTCGTCTTTG
CTGCATCGAACGGATTGATGAAACCCACGATGTGGTGACATTCCGATTTGAAGCCGCAGGGGAGCCTGTGCGTTTTAGTT
ATAAGCCGGGACAGTTTATCACCCTGTTGCTGGAGATTGGCGGCGAGCCCCACAGCCGGGCCTATACGCTGTCGTCTTCA
CCGTCCCGGCCCTACAGCATCAGCATCACTGTTAAACGGGTCGAGGGAGGCAAGGTTTCCAATTATCTGATTGATAATTT
AAGGCCAGGCCATGCTCTGGATGCCATGGGGCCATCTGGCAGTTTTAATCTGGTGGATATTCCTGCTGACAGGTATTTAT
TTTTAAGCGCGGGATGCGGCATTACGCCGATGTTCAGTATGAGCCGCTGGCTGACGGATACCCGTGTGGGCGCCGACATC
ACTTTTGTTCACAGCGCCAGGAGCGTCGATGACCTGATATTTGCTCCCAAGCTTGAGTCCATGGCGAACAACCACAGTGG
TTTTCGTCTCGGGTACGTAATTGAACAGGGTAATTGCCCTGACTGGCCCTATGCCCCCGTGCTGCCGGGGCGCTTGACGC
TATCTGGATTGGATTCCCTGGTCAGTGATTGGCGTGAGAGAACCTTGTATGTCTGTGGCCCCGAGGCCTATATGGCTGCA
GTAGAGGCTATGGTCAGGGATGCAGGATTTGCGATGTCGCGCTTCCACAAGGAAAGCTTTGGCAAGCCGGGAGCGCCCGT
CAAAAGTAGCGGACAAGGATTTATGCTGAAGGTGGGAGATAAGCTGCATCCACTCGGTGAGTCGGGTTTGCTGCTTGAGG
GTATTGAGGCGCTTAAGCTACCCATCATTGCCGCCTGTCGCAGCGGTGTGTGTGGTGCCTGTAAGTGTCAGGTGCTGGAG
GGTGATGTTGAGAGGCTGTCAGAGATGACACTGACCGAAGAAGACAAAGCCAATGGTATGGTGCTGGCGTGCTCTGCCCG
GGCGCTTTCGAATATCAGCCTTAAGCTTTAA

Upstream 100 bases:

>100_bases
CACGGTGGAGGCCGATCTGAATGCGATTCTGAATGTCGCCTGAGTTGATGCAAGACGGCGCAAAGCGCTGTCTCTTTCAT
TGTGTTGGGGATAATCAGTT

Downstream 100 bases:

>100_bases
GTCAGTTATGGTGGCTATACTTGGGCTGTTTTTTGGGGCCATGGTTGCGCTTTTGCCGATGGGAAAGTAAGGTTAAATCA
GGGCCGTGATCACAGTTTTG

Product: iron-sulfur cluster-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSQHRDAAFLTAKSWQDLPASVPFRLCCIERIDETHDVVTFRFEAAGEPVRFSYKPGQFITLLLEIGGEPHSRAYTLSSS
PSRPYSISITVKRVEGGKVSNYLIDNLRPGHALDAMGPSGSFNLVDIPADRYLFLSAGCGITPMFSMSRWLTDTRVGADI
TFVHSARSVDDLIFAPKLESMANNHSGFRLGYVIEQGNCPDWPYAPVLPGRLTLSGLDSLVSDWRERTLYVCGPEAYMAA
VEAMVRDAGFAMSRFHKESFGKPGAPVKSSGQGFMLKVGDKLHPLGESGLLLEGIEALKLPIIAACRSGVCGACKCQVLE
GDVERLSEMTLTEEDKANGMVLACSARALSNISLKL

Sequences:

>Translated_356_residues
MSQHRDAAFLTAKSWQDLPASVPFRLCCIERIDETHDVVTFRFEAAGEPVRFSYKPGQFITLLLEIGGEPHSRAYTLSSS
PSRPYSISITVKRVEGGKVSNYLIDNLRPGHALDAMGPSGSFNLVDIPADRYLFLSAGCGITPMFSMSRWLTDTRVGADI
TFVHSARSVDDLIFAPKLESMANNHSGFRLGYVIEQGNCPDWPYAPVLPGRLTLSGLDSLVSDWRERTLYVCGPEAYMAA
VEAMVRDAGFAMSRFHKESFGKPGAPVKSSGQGFMLKVGDKLHPLGESGLLLEGIEALKLPIIAACRSGVCGACKCQVLE
GDVERLSEMTLTEEDKANGMVLACSARALSNISLKL
>Mature_355_residues
SQHRDAAFLTAKSWQDLPASVPFRLCCIERIDETHDVVTFRFEAAGEPVRFSYKPGQFITLLLEIGGEPHSRAYTLSSSP
SRPYSISITVKRVEGGKVSNYLIDNLRPGHALDAMGPSGSFNLVDIPADRYLFLSAGCGITPMFSMSRWLTDTRVGADIT
FVHSARSVDDLIFAPKLESMANNHSGFRLGYVIEQGNCPDWPYAPVLPGRLTLSGLDSLVSDWRERTLYVCGPEAYMAAV
EAMVRDAGFAMSRFHKESFGKPGAPVKSSGQGFMLKVGDKLHPLGESGLLLEGIEALKLPIIAACRSGVCGACKCQVLEG
DVERLSEMTLTEEDKANGMVLACSARALSNISLKL

Specific function: NADH oxidoreductase acting in concert with HCP [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787098, Length=340, Percent_Identity=34.1176470588235, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1787658, Length=338, Percent_Identity=30.4733727810651, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788903, Length=228, Percent_Identity=28.5087719298246, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788104, Length=307, Percent_Identity=26.7100977198697, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38747; Mature: 38616

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQHRDAAFLTAKSWQDLPASVPFRLCCIERIDETHDVVTFRFEAAGEPVRFSYKPGQFI
CCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCEE
TLLLEIGGEPHSRAYTLSSSPSRPYSISITVKRVEGGKVSNYLIDNLRPGHALDAMGPSG
EEEEECCCCCCCCEEEECCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCEECCCCCCC
SFNLVDIPADRYLFLSAGCGITPMFSMSRWLTDTRVGADITFVHSARSVDDLIFAPKLES
CEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHEECCCHHH
MANNHSGFRLGYVIEQGNCPDWPYAPVLPGRLTLSGLDSLVSDWRERTLYVCGPEAYMAA
HHCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCEEEEECCHHHHHH
VEAMVRDAGFAMSRFHKESFGKPGAPVKSSGQGFMLKVGDKLHPLGESGLLLEGIEALKL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
PIIAACRSGVCGACKCQVLEGDVERLSEMTLTEEDKANGMVLACSARALSNISLKL
HHHHHHHCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEEC
>Mature Secondary Structure 
SQHRDAAFLTAKSWQDLPASVPFRLCCIERIDETHDVVTFRFEAAGEPVRFSYKPGQFI
CCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCEEEEECCCCEE
TLLLEIGGEPHSRAYTLSSSPSRPYSISITVKRVEGGKVSNYLIDNLRPGHALDAMGPSG
EEEEECCCCCCCCEEEECCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCEECCCCCCC
SFNLVDIPADRYLFLSAGCGITPMFSMSRWLTDTRVGADITFVHSARSVDDLIFAPKLES
CEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHEECCCHHH
MANNHSGFRLGYVIEQGNCPDWPYAPVLPGRLTLSGLDSLVSDWRERTLYVCGPEAYMAA
HHCCCCCEEEEEEEECCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCEEEEECCHHHHHH
VEAMVRDAGFAMSRFHKESFGKPGAPVKSSGQGFMLKVGDKLHPLGESGLLLEGIEALKL
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
PIIAACRSGVCGACKCQVLEGDVERLSEMTLTEEDKANGMVLACSARALSNISLKL
HHHHHHHCCCCCCEEEEEECCHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10651802 [H]