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The map label for this gene is aroF [H]

Identifier: 119774030

GI number: 119774030

Start: 1080314

End: 1081405

Strand: Direct

Name: aroF [H]

Synonym: Sama_0893

Alternate gene names: 119774030

Gene position: 1080314-1081405 (Clockwise)

Preceding gene: 119774029

Following gene: 119774031

Centisome position: 25.09

GC content: 53.11

Gene sequence:

>1092_bases
ATGCAGCAAGATACTATCAACAATGTGCACATCAGCGCCGAAAAGGTGCTTATCACGCCACAGGAGCTAAAACGCGAACT
GCCATTGTCTGAGCATGGGTACCAGTATATTTTGCGCTCCCGTCGTACTGTGGCAGATATTGTACACAAGCGCGACCCGC
GGCTGCTGGTGGTGGCAGGTCCTTGCTCAATCCACGATATTGCCGCCGCCAAGGAATATGCCCTTAAGCTTAAAAAGCTC
CATGACGAGCTCAAAGATGAGTTCTTTATTCTGATGCGGGTTTACTTCGAAAAGCCACGTACTACTGTGGGCTGGAAGGG
AATGATTAACGACCCTGATATGGATGAGTCCTTCGATGTGGAAAAGGGACTTCGTCTTGCCCGTGAGTTGATGATTTTTC
TGGCGGAGCTTGAACTGCCGGTGGCCACAGAGGCGCTCGACCCCATCAGCCCACAGTACATTTCAGAGCTTGTTACCTGG
TCTGCCATTGGCGCCCGCACCACAGAGTCTCAAACCCACAGGGAAATGGCGTCGGGCCTTTCTATGCCGGTGGGCTTTAA
AAACGGCACCGATGGCAAGCTGGATGTGGCAATCAATGCCATGAAATCGGCCGCCAGTGGTCACCGCTTTATGGGTATTA
ACCAGCAAGGTCAGGTAGCGCTTTTGCAAACCAACGGTAACCCGGATGGCCATATCATTCTGCGTGGTGGCAGCAAGCCC
AACTATGATGCTGAGAGTGTGGCCGAATGCGAGGCGCAGGTACGCTGGGCCGGGCTCGACCCCAAATTGGTCATAGATTG
CAGTCACGGTAATTCTTCCAAAGATCATAATCGTCAGGACCCGGTGTGTCGTGACGTGTTTGCTCAGGTGGCTGCCGGCA
GTGACGCCATTATCGGCGTGATGCTGGAAAGTCATCTCAATGCCGGTAACCAGCCCTGTGATAAGCCCCTGTCAGAGCTT
AAATACGGCGTCTCTGTCACCGATGCCTGCATAGATTGGCAAACGACCGAAACCTTGCTGCGTGAAGGTGCCGAGAACCT
GGCGTCTGTTATTCCCTCAAGATTTGTTATGCTGAAGGCCGCCAATGGCTGA

Upstream 100 bases:

>100_bases
ATGGTGTAACATTACAATAATACAAATTTTGGACGTAGAGATGTCAGCTGAGGTTGTCGATGGGGCAGTGTCAGCGTCGT
TAAACACAGAAGGTGATCCC

Downstream 100 bases:

>100_bases
CAGGATATTTGATATGACAGAAAAGACCACCGCTGAGCTGGAAAACCTACGGGGCCTGATTGATGGTGTCGACAGCCAGT
TACTGTCGCTGCTTCGCAAG

Product: phospho-2-dehydro-3-deoxyheptonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; DAHP synthase; Phospho-2-keto-3-deoxyheptonate aldolase [H]

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MQQDTINNVHISAEKVLITPQELKRELPLSEHGYQYILRSRRTVADIVHKRDPRLLVVAGPCSIHDIAAAKEYALKLKKL
HDELKDEFFILMRVYFEKPRTTVGWKGMINDPDMDESFDVEKGLRLARELMIFLAELELPVATEALDPISPQYISELVTW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGKLDVAINAMKSAASGHRFMGINQQGQVALLQTNGNPDGHIILRGGSKP
NYDAESVAECEAQVRWAGLDPKLVIDCSHGNSSKDHNRQDPVCRDVFAQVAAGSDAIIGVMLESHLNAGNQPCDKPLSEL
KYGVSVTDACIDWQTTETLLREGAENLASVIPSRFVMLKAANG

Sequences:

>Translated_363_residues
MQQDTINNVHISAEKVLITPQELKRELPLSEHGYQYILRSRRTVADIVHKRDPRLLVVAGPCSIHDIAAAKEYALKLKKL
HDELKDEFFILMRVYFEKPRTTVGWKGMINDPDMDESFDVEKGLRLARELMIFLAELELPVATEALDPISPQYISELVTW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGKLDVAINAMKSAASGHRFMGINQQGQVALLQTNGNPDGHIILRGGSKP
NYDAESVAECEAQVRWAGLDPKLVIDCSHGNSSKDHNRQDPVCRDVFAQVAAGSDAIIGVMLESHLNAGNQPCDKPLSEL
KYGVSVTDACIDWQTTETLLREGAENLASVIPSRFVMLKAANG
>Mature_363_residues
MQQDTINNVHISAEKVLITPQELKRELPLSEHGYQYILRSRRTVADIVHKRDPRLLVVAGPCSIHDIAAAKEYALKLKKL
HDELKDEFFILMRVYFEKPRTTVGWKGMINDPDMDESFDVEKGLRLARELMIFLAELELPVATEALDPISPQYISELVTW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGKLDVAINAMKSAASGHRFMGINQQGQVALLQTNGNPDGHIILRGGSKP
NYDAESVAECEAQVRWAGLDPKLVIDCSHGNSSKDHNRQDPVCRDVFAQVAAGSDAIIGVMLESHLNAGNQPCDKPLSEL
KYGVSVTDACIDWQTTETLLREGAENLASVIPSRFVMLKAANG

Specific function: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) [H]

COG id: COG0722

COG function: function code E; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I DAHP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788953, Length=354, Percent_Identity=61.864406779661, Blast_Score=469, Evalue=1e-134,
Organism=Escherichia coli, GI1786969, Length=348, Percent_Identity=52.2988505747126, Blast_Score=363, Evalue=1e-102,
Organism=Escherichia coli, GI1787996, Length=341, Percent_Identity=48.6803519061584, Blast_Score=339, Evalue=2e-94,
Organism=Saccharomyces cerevisiae, GI6319726, Length=357, Percent_Identity=52.1008403361345, Blast_Score=359, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6320240, Length=340, Percent_Identity=50.2941176470588, Blast_Score=342, Evalue=8e-95,

Paralogues:

None

Copy number: 2,200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006219 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.54 [H]

Molecular weight: Translated: 40014; Mature: 40014

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQDTINNVHISAEKVLITPQELKRELPLSEHGYQYILRSRRTVADIVHKRDPRLLVVAG
CCCCCCCCEEEECCEEEECHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCCEEEEEC
PCSIHDIAAAKEYALKLKKLHDELKDEFFILMRVYFEKPRTTVGWKGMINDPDMDESFDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EKGLRLARELMIFLAELELPVATEALDPISPQYISELVTWSAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SMPVGFKNGTDGKLDVAINAMKSAASGHRFMGINQQGQVALLQTNGNPDGHIILRGGSKP
CCCCCCCCCCCCEEEEEHHHHHHHCCCCEEECCCCCCCEEEEEECCCCCCEEEEECCCCC
NYDAESVAECEAQVRWAGLDPKLVIDCSHGNSSKDHNRQDPVCRDVFAQVAAGSDAIIGV
CCCHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHH
MLESHLNAGNQPCDKPLSELKYGVSVTDACIDWQTTETLLREGAENLASVIPSRFVMLKA
HHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
ANG
CCC
>Mature Secondary Structure
MQQDTINNVHISAEKVLITPQELKRELPLSEHGYQYILRSRRTVADIVHKRDPRLLVVAG
CCCCCCCCEEEECCEEEECHHHHHHHCCCCCCCHHHHHHCCHHHHHHHHCCCCCEEEEEC
PCSIHDIAAAKEYALKLKKLHDELKDEFFILMRVYFEKPRTTVGWKGMINDPDMDESFDV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCH
EKGLRLARELMIFLAELELPVATEALDPISPQYISELVTWSAIGARTTESQTHREMASGL
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
SMPVGFKNGTDGKLDVAINAMKSAASGHRFMGINQQGQVALLQTNGNPDGHIILRGGSKP
CCCCCCCCCCCCEEEEEHHHHHHHCCCCEEECCCCCCCEEEEEECCCCCCEEEEECCCCC
NYDAESVAECEAQVRWAGLDPKLVIDCSHGNSSKDHNRQDPVCRDVFAQVAAGSDAIIGV
CCCHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHH
MLESHLNAGNQPCDKPLSELKYGVSVTDACIDWQTTETLLREGAENLASVIPSRFVMLKA
HHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEE
ANG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6146618; 6396419; 9205837; 9278503; 1977738; 6104668; 2857723; 9056491 [H]