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The map label for this gene is erpA

Identifier: 119773980

GI number: 119773980

Start: 1028356

End: 1028706

Strand: Direct

Name: erpA

Synonym: Sama_0843

Alternate gene names: 119773980

Gene position: 1028356-1028706 (Clockwise)

Preceding gene: 119773979

Following gene: 119773984

Centisome position: 23.88

GC content: 53.85

Gene sequence:

>351_bases
ATGACTGAACAAACTGACGTAGCCATGCCCATCTCTTTCACCGATGCAGCGGCTGCCAAAGTTAAGGCTCTGCTCGATGA
AGAGCAGAATGATGCACTCAAGCTGCGCGTCTATGTTACCGGCGGTGGCTGTTCTGGGTTCCAGTACGGTTTCACCTTCG
ATGAAAAGGTGAACGACGGCGATTTCACCGTGGAAAAGCAGGGTGTTCAGCTGGTGGTCGACCCCATGAGTCTGCAATAC
CTGATGGGCGGTGAAGTGGATTACACTTCAGGCTTGGAAGGCTCACGCTTCTTTGTGAAGAACCCCAACGCCACCACCAC
CTGTGGCTGTGGCGCCAGCTTCTCTGTGTAA

Upstream 100 bases:

>100_bases
CCGATGCTGACGGGAGAGACAAAAGAGCCCGGTATAATACTTGAACAAAATAGTCAGGTAACGGATAATTCCGGGCAGCA
ATCTGAAGTTCGAGGTAGTA

Downstream 100 bases:

>100_bases
GCTGTTTTGCCCATAAATAAAAAAGCCGCCCCAGGGCGGCTTTTTTATTTGGCTATTCGGTAGCTTAACCTTTCGCAGGC
TGGTACCTCAGCTCATCAGG

Product: iron-sulfur cluster insertion protein ErpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 116; Mature: 115

Protein sequence:

>116_residues
MTEQTDVAMPISFTDAAAAKVKALLDEEQNDALKLRVYVTGGGCSGFQYGFTFDEKVNDGDFTVEKQGVQLVVDPMSLQY
LMGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV

Sequences:

>Translated_116_residues
MTEQTDVAMPISFTDAAAAKVKALLDEEQNDALKLRVYVTGGGCSGFQYGFTFDEKVNDGDFTVEKQGVQLVVDPMSLQY
LMGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
>Mature_115_residues
TEQTDVAMPISFTDAAAAKVKALLDEEQNDALKLRVYVTGGGCSGFQYGFTFDEKVNDGDFTVEKQGVQLVVDPMSLQYL
MGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV

Specific function: Required for insertion of 4Fe-4S clusters for at least ispG

COG id: COG0316

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesB/iscA family

Homologues:

Organism=Homo sapiens, GI160420328, Length=107, Percent_Identity=42.0560747663551, Blast_Score=78, Evalue=2e-15,
Organism=Homo sapiens, GI52426768, Length=106, Percent_Identity=32.0754716981132, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786351, Length=111, Percent_Identity=75.6756756756757, Blast_Score=182, Evalue=3e-48,
Organism=Escherichia coli, GI1788877, Length=110, Percent_Identity=40.9090909090909, Blast_Score=72, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71998452, Length=118, Percent_Identity=38.9830508474576, Blast_Score=82, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193209025, Length=114, Percent_Identity=34.2105263157895, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25146411, Length=114, Percent_Identity=35.0877192982456, Blast_Score=79, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323001, Length=106, Percent_Identity=35.8490566037736, Blast_Score=72, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649697, Length=83, Percent_Identity=46.9879518072289, Blast_Score=76, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24642263, Length=106, Percent_Identity=33.9622641509434, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ERPA_SHEAM (A1S3U4)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926720.1
- ProteinModelPortal:   A1S3U4
- SMR:   A1S3U4
- STRING:   A1S3U4
- GeneID:   4603095
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0843
- NMPDR:   fig|326297.7.peg.794
- eggNOG:   COG0316
- HOGENOM:   HBG730174
- OMA:   TFDDQIN
- PhylomeDB:   A1S3U4
- ProtClustDB:   PRK13623
- HAMAP:   MF_01380
- InterPro:   IPR000361
- InterPro:   IPR016092
- InterPro:   IPR017870
- InterPro:   IPR023063
- Gene3D:   G3DSA:2.60.300.12
- PANTHER:   PTHR10072
- TIGRFAMs:   TIGR00049

Pfam domain/function: PF01521 Fe-S_biosyn; SSF89360 HesB_yadR_yfhF-like

EC number: NA

Molecular weight: Translated: 12430; Mature: 12299

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS01152 HESB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEQTDVAMPISFTDAAAAKVKALLDEEQNDALKLRVYVTGGGCSGFQYGFTFDEKVNDG
CCCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEECCCCCCC
DFTVEKQGVQLVVDPMSLQYLMGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
CEEEECCCCEEEECCCEEEEEECCCEEECCCCCCCEEEEECCCCCEEECCCCCCCC
>Mature Secondary Structure 
TEQTDVAMPISFTDAAAAKVKALLDEEQNDALKLRVYVTGGGCSGFQYGFTFDEKVNDG
CCCCCEEEEEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCEEECCCCCCC
DFTVEKQGVQLVVDPMSLQYLMGGEVDYTSGLEGSRFFVKNPNATTTCGCGASFSV
CEEEECCCCEEEECCCEEEEEECCCEEECCCCCCCEEEEECCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA