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The map label for this gene is gcp

Identifier: 119773964

GI number: 119773964

Start: 1011529

End: 1012542

Strand: Direct

Name: gcp

Synonym: Sama_0827

Alternate gene names: 119773964

Gene position: 1011529-1012542 (Clockwise)

Preceding gene: 119773959

Following gene: 119773966

Centisome position: 23.49

GC content: 56.8

Gene sequence:

>1014_bases
ATGCGGGTTTTGGGAATCGAGACGTCCTGTGATGAAACAGGCATCGCCATCTACGACGAAGAGAAAGGCCTGATGGCCCA
CACTCTGTACAGCCAGGTCAAACTGCACGCCGATTACGGTGGGGTTGTGCCTGAGCTGGCTTCCCGTGACCATGTGCGTA
AGATTATTCCGCTTATTCGCGAAGCCCTGAAAAATGCCGATACCCGTATCGAAGATCTGGATGGGATCTGCTACACCAAG
GGCCCCGGTCTGATTGGTGCGCTGCTGGTTGGCGCCTGTGTAGGCCGCTCGTTGGCGTTTTCCTGGAATCTGCCCGCCGT
GGGTGTGCACCATATGGAAGGCCATTTGCTGGCACCGATGCTCGAAGACGAGGTGCCTGAGTTCCCCTTTGTGGCGCTGC
TGGTTTCCGGTGGTCATTCTATGCTGGTGAAAGTAGATGGTATAGGCCAGTACGAGGTGCTTGGTGAGTCCATCGATGAT
GCCGCCGGAGAGGCCTTCGATAAAACGGCCAAGCTGATGGGGCTTGATTATCCGGGCGGTCCGCGTCTTGCCAAGCTCGC
GGCCTCGGGTCAGCCAGCCAACTACAAGTTTCCGCGCCCAATGACCGACAGACCCGGGCTGGACTTCAGTTTCTCCGGGC
TTAAAACCTTCGTAGCCAATACTATCGCTGCCGAACCGGATGATGAGCAGACCCGCGCCAATATCGCCCGTGCTTTCGAA
GAGGCGGTGGTGGATACCCTGTCTATCAAGTGTCGCCGAGCACTGGAGCAAACCGGTTACAAACGCCTTGTTATTGCCGG
TGGTGTGAGTGCCAACGTGCGCCTGCGCGCAGGTCTTGCAGAGCTGATGGAAAAACTGGGTGGCAAGGTGTACTACCCCC
GAGGGGAATTCTGTACCGACAATGGTGCCATGATTGCCTATGCCGGTTTGCAGAGGCTGAAAGCGGGACAGCTTGAAGAT
TTGGCAGTAAAAGGTCAGCCTCGATGGCCACTGGATACCTTGCTACCGGTGTGA

Upstream 100 bases:

>100_bases
TAAAAAGGATCGCCTGAGGATCTGAGACGCGGCTTTACTGGAGTAATACTAGCTTAACGGGTAGAATTGGCCGCCCTTTT
AAGCGGAGAAACGACACAAA

Downstream 100 bases:

>100_bases
ACAAGGTGAAGCGTGTTGAGCACCACGCATTACCCATACACTCTTCATCTATTAAAGCTTCACCCATAAACACGTTATCC
AAAAAAATGGCGCCCTGGGC

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRVLGIETSCDETGIAIYDEEKGLMAHTLYSQVKLHADYGGVVPELASRDHVRKIIPLIREALKNADTRIEDLDGICYTK
GPGLIGALLVGACVGRSLAFSWNLPAVGVHHMEGHLLAPMLEDEVPEFPFVALLVSGGHSMLVKVDGIGQYEVLGESIDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAASGQPANYKFPRPMTDRPGLDFSFSGLKTFVANTIAAEPDDEQTRANIARAFE
EAVVDTLSIKCRRALEQTGYKRLVIAGGVSANVRLRAGLAELMEKLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQLED
LAVKGQPRWPLDTLLPV

Sequences:

>Translated_337_residues
MRVLGIETSCDETGIAIYDEEKGLMAHTLYSQVKLHADYGGVVPELASRDHVRKIIPLIREALKNADTRIEDLDGICYTK
GPGLIGALLVGACVGRSLAFSWNLPAVGVHHMEGHLLAPMLEDEVPEFPFVALLVSGGHSMLVKVDGIGQYEVLGESIDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAASGQPANYKFPRPMTDRPGLDFSFSGLKTFVANTIAAEPDDEQTRANIARAFE
EAVVDTLSIKCRRALEQTGYKRLVIAGGVSANVRLRAGLAELMEKLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQLED
LAVKGQPRWPLDTLLPV
>Mature_337_residues
MRVLGIETSCDETGIAIYDEEKGLMAHTLYSQVKLHADYGGVVPELASRDHVRKIIPLIREALKNADTRIEDLDGICYTK
GPGLIGALLVGACVGRSLAFSWNLPAVGVHHMEGHLLAPMLEDEVPEFPFVALLVSGGHSMLVKVDGIGQYEVLGESIDD
AAGEAFDKTAKLMGLDYPGGPRLAKLAASGQPANYKFPRPMTDRPGLDFSFSGLKTFVANTIAAEPDDEQTRANIARAFE
EAVVDTLSIKCRRALEQTGYKRLVIAGGVSANVRLRAGLAELMEKLGGKVYYPRGEFCTDNGAMIAYAGLQRLKAGQLED
LAVKGQPRWPLDTLLPV

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=33.5211267605634, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI8923380, Length=328, Percent_Identity=32.6219512195122, Blast_Score=140, Evalue=2e-33,
Organism=Escherichia coli, GI1789445, Length=334, Percent_Identity=75.1497005988024, Blast_Score=519, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI17557464, Length=328, Percent_Identity=29.5731707317073, Blast_Score=151, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI71995670, Length=325, Percent_Identity=31.6923076923077, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320099, Length=371, Percent_Identity=33.9622641509434, Blast_Score=183, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6322891, Length=348, Percent_Identity=27.5862068965517, Blast_Score=116, Evalue=4e-27,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=34.3195266272189, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI21357207, Length=329, Percent_Identity=32.5227963525836, Blast_Score=155, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_SHEAM (A1S3S8)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_926704.1
- ProteinModelPortal:   A1S3S8
- SMR:   A1S3S8
- STRING:   A1S3S8
- MEROPS:   M22.001
- GeneID:   4603079
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_0827
- NMPDR:   fig|326297.7.peg.778
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- PhylomeDB:   A1S3S8
- ProtClustDB:   PRK09604
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 36366; Mature: 36366

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAIYDEEKGLMAHTLYSQVKLHADYGGVVPELASRDHVRKIIPLIR
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
EALKNADTRIEDLDGICYTKGPGLIGALLVGACVGRSLAFSWNLPAVGVHHMEGHLLAPM
HHHHCCCCCHHHCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCEECCH
LEDEVPEFPFVALLVSGGHSMLVKVDGIGQYEVLGESIDDAAGEAFDKTAKLMGLDYPGG
HHHCCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHEECCCCCC
PRLAKLAASGQPANYKFPRPMTDRPGLDFSFSGLKTFVANTIAAEPDDEQTRANIARAFE
CHHHHHCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EAVVDTLSIKCRRALEQTGYKRLVIAGGVSANVRLRAGLAELMEKLGGKVYYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHHHHHHHHCCEEECCCCCEECC
NGAMIAYAGLQRLKAGQLEDLAVKGQPRWPLDTLLPV
CCCEEEEHHHHHHCCCCCCCEEECCCCCCCHHHHCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAIYDEEKGLMAHTLYSQVKLHADYGGVVPELASRDHVRKIIPLIR
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
EALKNADTRIEDLDGICYTKGPGLIGALLVGACVGRSLAFSWNLPAVGVHHMEGHLLAPM
HHHHCCCCCHHHCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCEECCH
LEDEVPEFPFVALLVSGGHSMLVKVDGIGQYEVLGESIDDAAGEAFDKTAKLMGLDYPGG
HHHCCCCCCEEEEEEECCCEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHEECCCCCC
PRLAKLAASGQPANYKFPRPMTDRPGLDFSFSGLKTFVANTIAAEPDDEQTRANIARAFE
CHHHHHCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
EAVVDTLSIKCRRALEQTGYKRLVIAGGVSANVRLRAGLAELMEKLGGKVYYPRGEFCTD
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEEEHHHHHHHHHHHCCEEECCCCCEECC
NGAMIAYAGLQRLKAGQLEDLAVKGQPRWPLDTLLPV
CCCEEEEHHHHHHCCCCCCCEEECCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA