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The map label for this gene is fbp [H]

Identifier: 119773958

GI number: 119773958

Start: 1004610

End: 1004948

Strand: Direct

Name: fbp [H]

Synonym: Sama_0821

Alternate gene names: 119773958

Gene position: 1004610-1004948 (Clockwise)

Preceding gene: 119773956

Following gene: 119773959

Centisome position: 23.33

GC content: 54.28

Gene sequence:

>339_bases
ATGTCTGAACTCCAAATAGAAGATGTGATTGAGGGCGAGGGTAAGGCGGCGGTAAAGGGCGCCCTTATTACTACGCACTA
CCGTGGTTGGCTCGCCGATGGCACCCAGTTTGATTCCTCCCATGACAGGGGCCAGGCATTTCAGTGCGTGATAGGCACAG
GTCGGGTTATCAAGGGATGGGATCAGGGCATTATCGGCATGAAGGTCGGTGGTAAGCGTCGTTTGCAGGTGCCTGCGCAT
CTGGCCTATGGTGAGCGCCAGATTGGCAATATGATCCCGCCAAACTCGGATTTGACCTTCGAGATTGAACTGCTGGAAGT
CTTAACCCGGGATGACTGA

Upstream 100 bases:

>100_bases
ACCACTTTCGGACACCTTGGGTGTCCGCTGATGACGAAGTGTCCGTTATTTGCTGTGGTACACTCAGCCTTTATTGATTA
ATTGCGAAAGACGAGTCTTT

Downstream 100 bases:

>100_bases
ACCATCCCACGCAAAAAAGCCCATGTTCCCATGGGCTTTTTTGTATCTGCGAATGTCGCGGTAAGTCACCGGTCCTTGGC
GTACACTGATATAACCGCCG

Product: peptidyl-prolyl cis-trans isomerase FkbP

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 112; Mature: 111

Protein sequence:

>112_residues
MSELQIEDVIEGEGKAAVKGALITTHYRGWLADGTQFDSSHDRGQAFQCVIGTGRVIKGWDQGIIGMKVGGKRRLQVPAH
LAYGERQIGNMIPPNSDLTFEIELLEVLTRDD

Sequences:

>Translated_112_residues
MSELQIEDVIEGEGKAAVKGALITTHYRGWLADGTQFDSSHDRGQAFQCVIGTGRVIKGWDQGIIGMKVGGKRRLQVPAH
LAYGERQIGNMIPPNSDLTFEIELLEVLTRDD
>Mature_111_residues
SELQIEDVIEGEGKAAVKGALITTHYRGWLADGTQFDSSHDRGQAFQCVIGTGRVIKGWDQGIIGMKVGGKRRLQVPAHL
AYGERQIGNMIPPNSDLTFEIELLEVLTRDD

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=94, Percent_Identity=50, Blast_Score=96, Evalue=6e-21,
Organism=Homo sapiens, GI17149844, Length=94, Percent_Identity=50, Blast_Score=96, Evalue=6e-21,
Organism=Homo sapiens, GI17149842, Length=94, Percent_Identity=50, Blast_Score=96, Evalue=6e-21,
Organism=Homo sapiens, GI192448443, Length=93, Percent_Identity=44.0860215053763, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI33469985, Length=113, Percent_Identity=38.9380530973451, Blast_Score=89, Evalue=6e-19,
Organism=Homo sapiens, GI17149836, Length=105, Percent_Identity=38.0952380952381, Blast_Score=85, Evalue=1e-17,
Organism=Homo sapiens, GI4503725, Length=105, Percent_Identity=38.0952380952381, Blast_Score=85, Evalue=1e-17,
Organism=Homo sapiens, GI4503729, Length=106, Percent_Identity=43.3962264150943, Blast_Score=80, Evalue=3e-16,
Organism=Homo sapiens, GI4758380, Length=105, Percent_Identity=38.0952380952381, Blast_Score=79, Evalue=6e-16,
Organism=Homo sapiens, GI8923659, Length=91, Percent_Identity=46.1538461538462, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI224809331, Length=92, Percent_Identity=43.4782608695652, Blast_Score=76, Evalue=5e-15,
Organism=Homo sapiens, GI224809329, Length=92, Percent_Identity=43.4782608695652, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI224809327, Length=92, Percent_Identity=43.4782608695652, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI4758384, Length=92, Percent_Identity=43.4782608695652, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI4503727, Length=97, Percent_Identity=37.1134020618557, Blast_Score=72, Evalue=7e-14,
Organism=Homo sapiens, GI206725547, Length=100, Percent_Identity=41, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI150010552, Length=111, Percent_Identity=39.6396396396396, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI31317231, Length=101, Percent_Identity=40.5940594059406, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI7706131, Length=108, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87082390, Length=107, Percent_Identity=44.8598130841121, Blast_Score=86, Evalue=6e-19,
Organism=Escherichia coli, GI1789745, Length=100, Percent_Identity=41, Blast_Score=67, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17540882, Length=89, Percent_Identity=50.561797752809, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71993519, Length=100, Percent_Identity=47, Blast_Score=90, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17561782, Length=106, Percent_Identity=39.622641509434, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17561778, Length=107, Percent_Identity=39.2523364485981, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6324194, Length=106, Percent_Identity=50.9433962264151, Blast_Score=109, Evalue=9e-26,
Organism=Saccharomyces cerevisiae, GI6320727, Length=92, Percent_Identity=53.2608695652174, Blast_Score=104, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6323482, Length=102, Percent_Identity=44.1176470588235, Blast_Score=87, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6323566, Length=102, Percent_Identity=44.1176470588235, Blast_Score=85, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363946, Length=89, Percent_Identity=51.685393258427, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17352457, Length=89, Percent_Identity=51.685393258427, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655568, Length=105, Percent_Identity=45.7142857142857, Blast_Score=98, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21356629, Length=107, Percent_Identity=45.7943925233645, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24647110, Length=104, Percent_Identity=43.2692307692308, Blast_Score=87, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583150, Length=96, Percent_Identity=40.625, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12323; Mature: 12192

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELQIEDVIEGEGKAAVKGALITTHYRGWLADGTQFDSSHDRGQAFQCVIGTGRVIKGW
CCCCCCCHHHCCCCCEEEECEEEEEECCCEECCCCCCCCCCCCCCEEEEEECCCEEEECC
DQGIIGMKVGGKRRLQVPAHLAYGERQIGNMIPPNSDLTFEIELLEVLTRDD
CCCEEEEEECCCEEEECCCEECCCCHHCCCCCCCCCCCEEEEEEHHHHHCCC
>Mature Secondary Structure 
SELQIEDVIEGEGKAAVKGALITTHYRGWLADGTQFDSSHDRGQAFQCVIGTGRVIKGW
CCCCCCHHHCCCCCEEEECEEEEEECCCEECCCCCCCCCCCCCCEEEEEECCCEEEECC
DQGIIGMKVGGKRRLQVPAHLAYGERQIGNMIPPNSDLTFEIELLEVLTRDD
CCCEEEEEECCCEEEECCCEECCCCHHCCCCCCCCCCCEEEEEEHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]