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The map label for this gene is cobQ [H]

Identifier: 119773902

GI number: 119773902

Start: 947505

End: 949013

Strand: Direct

Name: cobQ [H]

Synonym: Sama_0765

Alternate gene names: 119773902

Gene position: 947505-949013 (Clockwise)

Preceding gene: 119773901

Following gene: 119773903

Centisome position: 22.0

GC content: 57.72

Gene sequence:

>1509_bases
ATGGGCTTTTCTACGCTGATGATCCAGGGCACGGCCTCGGATGCCGGTAAAACCACGCTGGTCGCCGGGTTGTGTCGCCT
GCTCGCCAGACAAGGCCTGAAGGTCGCACCGTTCAAACCGCAGAATATGGCCCTCAACAGTGCAGTGACCGAAGACGGTG
GCGAGATAGGCCGCGCTCAGGCGTTGCAGGCGGCCGCCTGTGGGCTGAAACCCCATACCGATTTTAATCCCATATTGCTC
AAGCCGGGCTCAGACACCCGGGCGCAGGTTATCGTACACGGCAAGGCGCTCACGTCCCTCGAAGCATCGGCTTTTTTCGG
TCCCGAGGGTAAGGGATACAAGGCCATTGCCATCGAGGCGGTGCTGGAATCTTACAATCGCCTCAAGCAGTCTTTCGATT
ATCTTCTTGTGGAGGGCGCCGGCAGCCCTGCCGAAATCAACCTGCGGGAAAACGACATCGCCAACATGGGCTTTGCCGAA
GCGGTGGACTGCCCGGTGATTTTGGTGGCCGATATCGACAAGGGCGGTGTATTTGCCCAGCTGGTTGGGACCCTGGCGCT
CTTGTCTGAATCTGAGCAGGCGCGTATCAAGGGCTTTGTGATTAACCGTTTTCGCGGTGATATCAACCTGCTGCAACCTG
GGCTGGATTGGCTTGAGGCCCATACCGGCAAACCCGTGCTGGGTGTGGTGCCCTATTTACATAATCTGTTGCTGGACGCC
GAAGATGCCTTGGTGCCCTACCAGCAGGCCGGTGCCGATTCCGGGGCCCGGTTTCGGGTGAGGGTGTTGGTGTATCCGCG
TACCAGCAATCACACCGACTTTGACCCGCTGCGACTGCATCCGGGGGTGGATTTTGATTACCTTGATATTCAGCACGCCA
GCCCAGATGCGCTGCAGGGAGCCGACCTTGTGATACTCCCCGGAAGCAAGAATGTGCGTGCCGATCTTGAATGCCTCAAG
ACAAAAGGCTTTGACTGTGCCCTGCGAAAGCATGTGAGATACGGTGGCAAGCTGGTGGGCATTTGCGGCGGTTATCAGAT
GTTGGGGATAGAAATTGATGATCCCGACGGTGTAGAAGATACGCCCGGCAGTAGTGACGCGCTGGAATTCTTGCCCCTGA
TTACCGAGCTTGAAGGCAGCAAGGTGCTGGCCAATGTCTCGGGTGAGCTTAGCCTTGGCGAGGAGGCTGTAGCGGTTAAA
GGCTATGAAATTCACTGTGGCCGTACCACAGTGCTTGGCCAGCTTTCCAGGCCCTTATTTTTGGTGGACGACACTGGTAA
TCCTGCCAGTGACCGGGGCTGCATCAGCGACGACGGCGCCATCTTTGGCTGTTATCTTCACGGCATTTTCGATACCCCAG
CGGCGCTGGATGCCGTGCTTGCCTGGGCTGGTTATCGCGGTGCGGCCCGGGGCACTTCGCTGGAAGAGCACAGAGAACAG
CAGCTCGAACGGCTGGCCGATACCCTGGCTGAGCATCTGGATATGGCCCGGCTCAATTCTCTCTTTTAA

Upstream 100 bases:

>100_bases
GGCCATTGCCGCTATCGCAGACAGGGTGACTCTGGTGGTGGCCGGGCTGCCACTGGCGCTGAAAGGCATAGCCGTCAACG
CTGAAGTGGGAGCATAACCT

Downstream 100 bases:

>100_bases
TGACGCTATCAGGATATTTTGATGACTGAAATCAAGGCTGAGCGCCACAAGGCAAGGCAGCAAAAGGTCAAGGAAGCTGT
GGATGCCAAGGTGGCTGCCG

Product: cobyric acid synthase

Products: ADP; phosphate; adenosylcobyric acid; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MGFSTLMIQGTASDAGKTTLVAGLCRLLARQGLKVAPFKPQNMALNSAVTEDGGEIGRAQALQAAACGLKPHTDFNPILL
KPGSDTRAQVIVHGKALTSLEASAFFGPEGKGYKAIAIEAVLESYNRLKQSFDYLLVEGAGSPAEINLRENDIANMGFAE
AVDCPVILVADIDKGGVFAQLVGTLALLSESEQARIKGFVINRFRGDINLLQPGLDWLEAHTGKPVLGVVPYLHNLLLDA
EDALVPYQQAGADSGARFRVRVLVYPRTSNHTDFDPLRLHPGVDFDYLDIQHASPDALQGADLVILPGSKNVRADLECLK
TKGFDCALRKHVRYGGKLVGICGGYQMLGIEIDDPDGVEDTPGSSDALEFLPLITELEGSKVLANVSGELSLGEEAVAVK
GYEIHCGRTTVLGQLSRPLFLVDDTGNPASDRGCISDDGAIFGCYLHGIFDTPAALDAVLAWAGYRGAARGTSLEEHREQ
QLERLADTLAEHLDMARLNSLF

Sequences:

>Translated_502_residues
MGFSTLMIQGTASDAGKTTLVAGLCRLLARQGLKVAPFKPQNMALNSAVTEDGGEIGRAQALQAAACGLKPHTDFNPILL
KPGSDTRAQVIVHGKALTSLEASAFFGPEGKGYKAIAIEAVLESYNRLKQSFDYLLVEGAGSPAEINLRENDIANMGFAE
AVDCPVILVADIDKGGVFAQLVGTLALLSESEQARIKGFVINRFRGDINLLQPGLDWLEAHTGKPVLGVVPYLHNLLLDA
EDALVPYQQAGADSGARFRVRVLVYPRTSNHTDFDPLRLHPGVDFDYLDIQHASPDALQGADLVILPGSKNVRADLECLK
TKGFDCALRKHVRYGGKLVGICGGYQMLGIEIDDPDGVEDTPGSSDALEFLPLITELEGSKVLANVSGELSLGEEAVAVK
GYEIHCGRTTVLGQLSRPLFLVDDTGNPASDRGCISDDGAIFGCYLHGIFDTPAALDAVLAWAGYRGAARGTSLEEHREQ
QLERLADTLAEHLDMARLNSLF
>Mature_501_residues
GFSTLMIQGTASDAGKTTLVAGLCRLLARQGLKVAPFKPQNMALNSAVTEDGGEIGRAQALQAAACGLKPHTDFNPILLK
PGSDTRAQVIVHGKALTSLEASAFFGPEGKGYKAIAIEAVLESYNRLKQSFDYLLVEGAGSPAEINLRENDIANMGFAEA
VDCPVILVADIDKGGVFAQLVGTLALLSESEQARIKGFVINRFRGDINLLQPGLDWLEAHTGKPVLGVVPYLHNLLLDAE
DALVPYQQAGADSGARFRVRVLVYPRTSNHTDFDPLRLHPGVDFDYLDIQHASPDALQGADLVILPGSKNVRADLECLKT
KGFDCALRKHVRYGGKLVGICGGYQMLGIEIDDPDGVEDTPGSSDALEFLPLITELEGSKVLANVSGELSLGEEAVAVKG
YEIHCGRTTVLGQLSRPLFLVDDTGNPASDRGCISDDGAIFGCYLHGIFDTPAALDAVLAWAGYRGAARGTSLEEHREQQ
LERLADTLAEHLDMARLNSLF

Specific function: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation [H]

COG id: COG1492

COG function: function code H; Cobyric acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GATase cobBQ-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR017929
- InterPro:   IPR004459
- InterPro:   IPR011698 [H]

Pfam domain/function: PF01656 CbiA; PF07685 GATase_3 [H]

EC number: 6.3.5.10

Molecular weight: Translated: 53677; Mature: 53545

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFSTLMIQGTASDAGKTTLVAGLCRLLARQGLKVAPFKPQNMALNSAVTEDGGEIGRAQ
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEECHHHCCCCCHHHHHH
ALQAAACGLKPHTDFNPILLKPGSDTRAQVIVHGKALTSLEASAFFGPEGKGYKAIAIEA
HHHHHHCCCCCCCCCCCEEEECCCCCCEEEEEECCHHHCCCHHEEECCCCCCEEEEHHHH
VLESYNRLKQSFDYLLVEGAGSPAEINLRENDIANMGFAEAVDCPVILVADIDKGGVFAQ
HHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCHHHCCCCEEEEEECCCCCHHHH
LVGTLALLSESEQARIKGFVINRFRGDINLLQPGLDWLEAHTGKPVLGVVPYLHNLLLDA
HHHHHHHHCCCCCHHEEEEEEEECCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCC
EDALVPYQQAGADSGARFRVRVLVYPRTSNHTDFDPLRLHPGVDFDYLDIQHASPDALQG
CHHCCCHHHCCCCCCCEEEEEEEEEECCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCC
ADLVILPGSKNVRADLECLKTKGFDCALRKHVRYGGKLVGICGGYQMLGIEIDDPDGVED
CCEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCC
TPGSSDALEFLPLITELEGSKVLANVSGELSLGEEAVAVKGYEIHCGRTTVLGQLSRPLF
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECEEEECCCHHHHHHCCCCEE
LVDDTGNPASDRGCISDDGAIFGCYLHGIFDTPAALDAVLAWAGYRGAARGTSLEEHREQ
EEECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHH
QLERLADTLAEHLDMARLNSLF
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GFSTLMIQGTASDAGKTTLVAGLCRLLARQGLKVAPFKPQNMALNSAVTEDGGEIGRAQ
CCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCEECHHHCCCCCHHHHHH
ALQAAACGLKPHTDFNPILLKPGSDTRAQVIVHGKALTSLEASAFFGPEGKGYKAIAIEA
HHHHHHCCCCCCCCCCCEEEECCCCCCEEEEEECCHHHCCCHHEEECCCCCCEEEEHHHH
VLESYNRLKQSFDYLLVEGAGSPAEINLRENDIANMGFAEAVDCPVILVADIDKGGVFAQ
HHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCHHHCCCCEEEEEECCCCCHHHH
LVGTLALLSESEQARIKGFVINRFRGDINLLQPGLDWLEAHTGKPVLGVVPYLHNLLLDA
HHHHHHHHCCCCCHHEEEEEEEECCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHCC
EDALVPYQQAGADSGARFRVRVLVYPRTSNHTDFDPLRLHPGVDFDYLDIQHASPDALQG
CHHCCCHHHCCCCCCCEEEEEEEEEECCCCCCCCCCEEECCCCCEEEEEEECCCCCCCCC
ADLVILPGSKNVRADLECLKTKGFDCALRKHVRYGGKLVGICGGYQMLGIEIDDPDGVED
CCEEEECCCCCCHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECCEEEEEEEECCCCCCCC
TPGSSDALEFLPLITELEGSKVLANVSGELSLGEEAVAVKGYEIHCGRTTVLGQLSRPLF
CCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEECEEEECCCHHHHHHCCCCEE
LVDDTGNPASDRGCISDDGAIFGCYLHGIFDTPAALDAVLAWAGYRGAARGTSLEEHREQ
EEECCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHH
QLERLADTLAEHLDMARLNSLF
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; adenosylcobyrinic acid a,c-diamide; L-glutamine; H2O

Specific reaction: 4 ATP + adenosylcobyrinic acid a,c-diamide + 4 L-glutamine + 4 H2O = 4 ADP + 4 phosphate + adenosylcobyric acid + 4 L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA