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The map label for this gene is ykvY [H]

Identifier: 119773826

GI number: 119773826

Start: 852263

End: 853474

Strand: Direct

Name: ykvY [H]

Synonym: Sama_0688

Alternate gene names: 119773826

Gene position: 852263-853474 (Clockwise)

Preceding gene: 119773824

Following gene: 119773831

Centisome position: 19.79

GC content: 56.52

Gene sequence:

>1212_bases
ATGACCATAGGTGTTGGTGGGCTGACGGCCCAAGAGGCTCTGGCCAAACTCAGTGATATGACAGCGGGCACAGGCCCCAT
TGACGCGGCTGAATTTCAGGGGCGTATCCTCAAGGCGCAGGGGCTGATGAAAGCGGCAGGGTTGGATGCTGTGTACCTTA
ATGCCGGCACCAATCTTTACTACTTTACCGGTACCCGCTGGTACGCCAGCGAGCGTATGGTAGGTGCCATTCTGCCCGCA
GAAGGGGCGTTGGAATACATAGCACCGGCTTTTGAACTCGACACCCTCAAAGGCTATATGGCCATCAAGGGTGAAGTGAA
TACCTGGCATGAAGACGAAAGCCCTTATCAACTCTTTGGCTCAGTACTCAAACGCCTTGGCTTGGGGCAGGGGCGGGTGG
GTATGGATGAATCGGCTGCGTTTTTCATCAGTGAAGGTATTCGTGATGCCAACCCTGAGCTTAAGGTCGTAAGCGCCAAG
GCCGTGACGGCCGGTTGCCGGATGCAAAAATCGGCCGCTGAGCTGGCACTGATGCAACGCGCCAAGGACATGACCCTGGA
AGTACATAAGGCTGCCGCTGCTATGTTGCGGCCCGGTATCACTGTGAGTGAAGTGGAAGCCTTTATCGATGCTGCCCATC
GTAAAGTGGGAGCTCCGGCCGGCTCTTATTTTTGCATTGTGCTATTTGGTGAAGACACGGCGTATCCCCACGGCGTGAAA
AATCCCAAGGCGCTGGAAGAGGGCGATACCGTCCTGATTGACACCGGCTGCCAGCTCTATGGTTATAACTCAGATATCAC
CCGCACTTACGTTTATGGCACCCCGAGTGCGCGTCAGCGTGAACTCTGGAACCTGGAAAAACAGGCGCAGGCGGCTGCCT
TTGAGGCGGCCAGATTGGGCGCCCCCTGTGGCAGCGTCGATAAGGCCGCCCGCAGCGTGCTTGAGGCCGCAGGCTTTGGC
CCGGGCTATGCTGTTCCCGGCCTGCCACACCGTACAGGTCACGGCATAGGGCTGGATATTCACGAGTGGCCCTATCTGGT
GGCGAATGACACTACACCGCTGGCGCCGGGAATGTGTTTTTCCAACGAGCCCATGCTCTGTGTACCCGGTGAATTTGGGG
TACGCCTTGAGGATCACTTCTACATGACTGAGTCTGGCCCCAAATGGTTCACTCTCCCTTCCCATTCCATTGACAATCCG
TTTGGCTTGTAA

Upstream 100 bases:

>100_bases
AATGAGGTTCAATGTTTGTATATTTTATGCTAGAAATGCGCATCTGAATTGCGCCTCTGGCTGTGTTGGCCCGCGGCAAC
AAATGATTTAAAGGTGATGT

Downstream 100 bases:

>100_bases
GGGACAATAAAAAAACGGAGGCACAGGCCTCCGTTTTTTATTTCGCTTCAGTCAGCATTCATTCGATGGCTATCAGTTCC
ACATCGAAAATCAGCACAGA

Product: peptidase M24

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MTIGVGGLTAQEALAKLSDMTAGTGPIDAAEFQGRILKAQGLMKAAGLDAVYLNAGTNLYYFTGTRWYASERMVGAILPA
EGALEYIAPAFELDTLKGYMAIKGEVNTWHEDESPYQLFGSVLKRLGLGQGRVGMDESAAFFISEGIRDANPELKVVSAK
AVTAGCRMQKSAAELALMQRAKDMTLEVHKAAAAMLRPGITVSEVEAFIDAAHRKVGAPAGSYFCIVLFGEDTAYPHGVK
NPKALEEGDTVLIDTGCQLYGYNSDITRTYVYGTPSARQRELWNLEKQAQAAAFEAARLGAPCGSVDKAARSVLEAAGFG
PGYAVPGLPHRTGHGIGLDIHEWPYLVANDTTPLAPGMCFSNEPMLCVPGEFGVRLEDHFYMTESGPKWFTLPSHSIDNP
FGL

Sequences:

>Translated_403_residues
MTIGVGGLTAQEALAKLSDMTAGTGPIDAAEFQGRILKAQGLMKAAGLDAVYLNAGTNLYYFTGTRWYASERMVGAILPA
EGALEYIAPAFELDTLKGYMAIKGEVNTWHEDESPYQLFGSVLKRLGLGQGRVGMDESAAFFISEGIRDANPELKVVSAK
AVTAGCRMQKSAAELALMQRAKDMTLEVHKAAAAMLRPGITVSEVEAFIDAAHRKVGAPAGSYFCIVLFGEDTAYPHGVK
NPKALEEGDTVLIDTGCQLYGYNSDITRTYVYGTPSARQRELWNLEKQAQAAAFEAARLGAPCGSVDKAARSVLEAAGFG
PGYAVPGLPHRTGHGIGLDIHEWPYLVANDTTPLAPGMCFSNEPMLCVPGEFGVRLEDHFYMTESGPKWFTLPSHSIDNP
FGL
>Mature_402_residues
TIGVGGLTAQEALAKLSDMTAGTGPIDAAEFQGRILKAQGLMKAAGLDAVYLNAGTNLYYFTGTRWYASERMVGAILPAE
GALEYIAPAFELDTLKGYMAIKGEVNTWHEDESPYQLFGSVLKRLGLGQGRVGMDESAAFFISEGIRDANPELKVVSAKA
VTAGCRMQKSAAELALMQRAKDMTLEVHKAAAAMLRPGITVSEVEAFIDAAHRKVGAPAGSYFCIVLFGEDTAYPHGVKN
PKALEEGDTVLIDTGCQLYGYNSDITRTYVYGTPSARQRELWNLEKQAQAAAFEAARLGAPCGSVDKAARSVLEAAGFGP
GYAVPGLPHRTGHGIGLDIHEWPYLVANDTTPLAPGMCFSNEPMLCVPGEFGVRLEDHFYMTESGPKWFTLPSHSIDNPF
GL

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI93141226, Length=153, Percent_Identity=35.9477124183007, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI149589008, Length=240, Percent_Identity=25, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI260593665, Length=240, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI40385867, Length=205, Percent_Identity=24.8780487804878, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788728, Length=361, Percent_Identity=31.3019390581717, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1789275, Length=259, Percent_Identity=30.1158301158301, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1786364, Length=211, Percent_Identity=24.6445497630332, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508215, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI19920384, Length=303, Percent_Identity=28.7128712871287, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357079, Length=200, Percent_Identity=30, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 43201; Mature: 43069

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIGVGGLTAQEALAKLSDMTAGTGPIDAAEFQGRILKAQGLMKAAGLDAVYLNAGTNLY
CEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHCCEEEEHHCHHHHCCCCEEEEECCCEEE
YFTGTRWYASERMVGAILPAEGALEYIAPAFELDTLKGYMAIKGEVNTWHEDESPYQLFG
EECCCEEECCCCEEEEEECCCCCHHHHCCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHH
SVLKRLGLGQGRVGMDESAAFFISEGIRDANPELKVVSAKAVTAGCRMQKSAAELALMQR
HHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
AKDMTLEVHKAAAAMLRPGITVSEVEAFIDAAHRKVGAPAGSYFCIVLFGEDTAYPHGVK
HHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
NPKALEEGDTVLIDTGCQLYGYNSDITRTYVYGTPSARQRELWNLEKQAQAAAFEAARLG
CCCCCCCCCEEEEECCCEEEECCCCCEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHCC
APCGSVDKAARSVLEAAGFGPGYAVPGLPHRTGHGIGLDIHEWPYLVANDTTPLAPGMCF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCCCEE
SNEPMLCVPGEFGVRLEDHFYMTESGPKWFTLPSHSIDNPFGL
CCCCCEEECCCCCCEEECEEEEECCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TIGVGGLTAQEALAKLSDMTAGTGPIDAAEFQGRILKAQGLMKAAGLDAVYLNAGTNLY
EEECCCCCHHHHHHHHHHCCCCCCCCCHHHHCCEEEEHHCHHHHCCCCEEEEECCCEEE
YFTGTRWYASERMVGAILPAEGALEYIAPAFELDTLKGYMAIKGEVNTWHEDESPYQLFG
EECCCEEECCCCEEEEEECCCCCHHHHCCCHHHHCCCCEEEEECCCCCCCCCCCHHHHHH
SVLKRLGLGQGRVGMDESAAFFISEGIRDANPELKVVSAKAVTAGCRMQKSAAELALMQR
HHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHH
AKDMTLEVHKAAAAMLRPGITVSEVEAFIDAAHRKVGAPAGSYFCIVLFGEDTAYPHGVK
HHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCC
NPKALEEGDTVLIDTGCQLYGYNSDITRTYVYGTPSARQRELWNLEKQAQAAAFEAARLG
CCCCCCCCCEEEEECCCEEEECCCCCEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHCC
APCGSVDKAARSVLEAAGFGPGYAVPGLPHRTGHGIGLDIHEWPYLVANDTTPLAPGMCF
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCCCCEE
SNEPMLCVPGEFGVRLEDHFYMTESGPKWFTLPSHSIDNPFGL
CCCCCEEECCCCCCEEECEEEEECCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]