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The map label for this gene is glcB [H]

Identifier: 119773819

GI number: 119773819

Start: 842929

End: 843501

Strand: Direct

Name: glcB [H]

Synonym: Sama_0681

Alternate gene names: 119773819

Gene position: 842929-843501 (Clockwise)

Preceding gene: 119773817

Following gene: 119773823

Centisome position: 19.58

GC content: 54.28

Gene sequence:

>573_bases
ATGAACATGACCATGATGAATACCCAAAATCAGCAACAACTGCATCACTTCATCGGGGAAGCCATTGCCGCAGTGGTGAA
TGGTGCCAAACGGGGAGTCAGTCTCGAGAGTGCGACCGAATTTCTTGACCGCCGCTTTCCGCTGGCGCGGGGCAGTCATA
AGATGGTGAAAAGCTATGTGGTTTACTACCAGCACCTGCTGGCCTTCTTTGAAGACGGCAGCCACAGTGGGCTGGAAACC
TCTTCCCAGTTTGTAGCCCTGAGCGGTCACAAGGAAGAGCCCTGTGCCATCCTGCTCAAGTCAGGTGATATTCATGTGGA
GTTAACCCTGGATAAGAATGGCCGCATGGGCAGTGCCAATCCGGCCCATATCGAGGACATTCAGGTTGAGTCCCCCGGCT
TTTGCCTGAGAGAAAGCGAAGGCTGTGCCACAGAAGCCATCAGCCAATGCCGCAACTGGTTGAGCCTGCTGCACTCGGCT
CCCTGCGATGATGATTGCCGTCAGCGCAACGAGCGTCGCTTTACCGCAAAAGATGGCGGCGAGTATCAGTTGATGTCACT
GGGACTCTTTTAA

Upstream 100 bases:

>100_bases
AGACTAAAAATCAAGCGAAATTCACCGACTGCACGACGCACCCCACCGGCAGGATTTCGTGGCAAAACCCAAAAGAAGCT
AAGTGACCGAGGACAAGGCA

Downstream 100 bases:

>100_bases
CAAACGTCCTGGCTTCCATAAGCAAAAGCGATAAGTAAAAGGCCCGGTTAAACCGGGCCTTTTGCATTCATGCTGAGATG
GTCATGGCTACTCAGTGCCG

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MNMTMMNTQNQQQLHHFIGEAIAAVVNGAKRGVSLESATEFLDRRFPLARGSHKMVKSYVVYYQHLLAFFEDGSHSGLET
SSQFVALSGHKEEPCAILLKSGDIHVELTLDKNGRMGSANPAHIEDIQVESPGFCLRESEGCATEAISQCRNWLSLLHSA
PCDDDCRQRNERRFTAKDGGEYQLMSLGLF

Sequences:

>Translated_190_residues
MNMTMMNTQNQQQLHHFIGEAIAAVVNGAKRGVSLESATEFLDRRFPLARGSHKMVKSYVVYYQHLLAFFEDGSHSGLET
SSQFVALSGHKEEPCAILLKSGDIHVELTLDKNGRMGSANPAHIEDIQVESPGFCLRESEGCATEAISQCRNWLSLLHSA
PCDDDCRQRNERRFTAKDGGEYQLMSLGLF
>Mature_190_residues
MNMTMMNTQNQQQLHHFIGEAIAAVVNGAKRGVSLESATEFLDRRFPLARGSHKMVKSYVVYYQHLLAFFEDGSHSGLET
SSQFVALSGHKEEPCAILLKSGDIHVELTLDKNGRMGSANPAHIEDIQVESPGFCLRESEGCATEAISQCRNWLSLLHSA
PCDDDCRQRNERRFTAKDGGEYQLMSLGLF

Specific function: Accounts For Almost The Entire Malate-Synthesizing Activity In Cells Metabolizing Glyoxylate. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family. GlcB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789348, Length=157, Percent_Identity=33.7579617834395, Blast_Score=86, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR001465
- InterPro:   IPR006253 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 21165; Mature: 21165

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMTMMNTQNQQQLHHFIGEAIAAVVNGAKRGVSLESATEFLDRRFPLARGSHKMVKSYV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
VYYQHLLAFFEDGSHSGLETSSQFVALSGHKEEPCAILLKSGDIHVELTLDKNGRMGSAN
HHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCEEEEEEECCCCCCCCCC
PAHIEDIQVESPGFCLRESEGCATEAISQCRNWLSLLHSAPCDDDCRQRNERRFTAKDGG
CCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEECCCCC
EYQLMSLGLF
CEEEEEECCC
>Mature Secondary Structure
MNMTMMNTQNQQQLHHFIGEAIAAVVNGAKRGVSLESATEFLDRRFPLARGSHKMVKSYV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
VYYQHLLAFFEDGSHSGLETSSQFVALSGHKEEPCAILLKSGDIHVELTLDKNGRMGSAN
HHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCEEEEEECCCEEEEEEECCCCCCCCCC
PAHIEDIQVESPGFCLRESEGCATEAISQCRNWLSLLHSAPCDDDCRQRNERRFTAKDGG
CCCCEEEEECCCCCEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEECCCCC
EYQLMSLGLF
CEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]