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The map label for this gene is rpoC [H]

Identifier: 119773348

GI number: 119773348

Start: 242768

End: 246982

Strand: Direct

Name: rpoC [H]

Synonym: Sama_0207

Alternate gene names: 119773348

Gene position: 242768-246982 (Clockwise)

Preceding gene: 119773347

Following gene: 119773349

Centisome position: 5.64

GC content: 54.4

Gene sequence:

>4215_bases
GTGAAAGACTTATTAAAGTTTCTGAAACAGCAGGGTAAGACCGAAGAGTTTGAAGGTATCAAGATTGGTCTGGCTTCACC
TGACCTGATCCGTTCATGGTCTTTTGGTGAAGTTAAAAAGCCAGAAACCATTAACTACCGTACCTTTAAGCCTGAGCGTG
AAGGTCTGTTTTGTGCCCGCATCTTTGGTCCTGTGAAGGACTATGAGTGTCTGTGTGGTAAGTACAAGCGTCTGAAGCAT
CGCGGTGTCATCTGTGAGAAGTGCGGCGTTGAAGTTACCCAGACCAAGGTGCGCCGTGAGCGCATGGGTCACATCGAGCT
GGCCAGCCCAGTTGCCCACATCTGGTTCTTGAAGTCACTGCCGTCCCGTATCGGTTTGATGCTGGATATGACGCTGCGTG
ACATCGAGCGCGTGCTGTATTTCGAATCTTATGTCGTAATTGAGCCAGGCATGACCAGCCTGGAGCGCGGTCAGATGCTG
ACCGAAGAAAACTACCTGGATGCGCTGGAAGAATACGGTGATGAATTCGAAGCCAAAATGGGCGCCGAAGCCGTATTGGA
TCTGCTGCGTGCCATCGACCTCGAGAAAGAAATCGAGCAGATGCGCGAAGAGCTGCCTTCCATCAACTCTGAGACCCGTC
GCAAGAAAGTGACCAAGCGTCTGAAGCTGATTGAAGCCTTCTACACTTCTGGCAATAAGCCAGAGTGGATGATCCTCAAA
GTACTGCCAGTTCTGCCACCGGATCTGCGTCCGTTGGTTCCGCTGGACGGCGGTCGTTTCGCGACTTCGGATCTGAACGA
TCTGTATCGCCGCGTCATCAACCGTAACAACCGTCTGAAGCGTCTGCTGGATCTGGCTGCTCCGGATATCATCGTACGCA
ACGAAAAGCGTATGCTGCAGGAGTCTGTGGATGCGCTGCTGGACAACGGCCGTCGTGGCCGTGCCATTACCGGTTCCAAC
AAGCGTCCTCTGAAATCCCTGGCCGACATGATCAAGGGTAAGCAAGGTCGTTTCCGTCAGAACCTGCTGGGTAAGCGCGT
TGACTACTCAGGCCGTTCGGTTATTACCGTAGGTCCTACTCTGCGTCTGCATCAGTGCGGTCTGCCAAAGAAAATGGCTC
TTGAGCTGTTCAAGCCCTTCATCTACGGCAAGCTGGAAGGTCGTGGCCTGGCCACCACCATCAAAGCCGCCAAGAAGATG
GTAGAGCGTGAAGTTGCCGAGGTTTGGGACGTACTGGATGAAGTGATCCGCGAACACCCAGTAATGCTCAACCGTGCACC
AACACTGCACCGTCTGGGTATTCAGGCGTTCGAACCTGTACTGATTGAAGGTAAGGCAATCCAACTGCACCCACTGGTGT
GTGCGGCATACAACGCCGACTTCGACGGTGACCAGATGGCGGTACACGTACCTCTGACTCTGGAAGCTCAGCTGGAAGCC
CGTGCGCTGATGATGTCTACCAACAACATCCTGTCGCCAGCCAACGGTGAGCCAATCATCGTTCCTTCTCAGGACGTGGT
ATTGGGTCTGTACTACATCAGCCGTGAGCGTGTAAACGGTCGCGGTGAAGCCATGGCGTTCGAGTCTGTTGCTGAAGCTG
AAAAAGCCTACCGTGTAGGTGCTGCCGAGCTGCACGCCCGCGTGAAAGTTCGTATTACCGAAACCATCATTGGTGAAAAC
GGTGAGCGTACCAAGCAGCGTCGTATCGTTGACACCACAGTGGGTCGTGCCATCCTGTCGCAAATCCTGCCAGCCGGTCT
GTCTTTCGACCTGGTAAACCAGGACATGGGCAAGAAGCAGATCTCCAAGCTGCTGAACACCTGTTACCGTCAGCTGGGTC
TGAAAGATACCGTTATCTTCGCCGACCAACTGATGTACACCGGTTTCCAGTACGCCACCATCTCCGGTGCCTCTGTTGGT
ATTAACGACATGGTTATCCCAGAAGAGAAATACTCTCTTGTGGCCGATGCCGAAGCCGAAGTTATCGAGATCCAGGAACA
GTTCCAGTCTGGTCTGGTAACCGCCGGTGAGCGTTACAACAAGGTCATCGATATCTGGGCAAGTGCCAACGAGAAGGTGT
CCAAGGCGATGATGGAAAACCTGTCTTCCGAGACAGTGATCAACCGTCATGGCGAAGAAGAAAAGCAGAAGTCGTTCAAC
AGCATCTACATGATGGCCGACTCAGGCGCGCGGGGTAGTGCCGCTCAGATCCGTCAGTTGGCGGGTATGCGTGGTCTGAT
GGCCAAGCCAGACGGCTCCATCATTGAAACGCCCATCGTGGCGAACTTCCGTGAAGGTCTGAACGTACTCCAGTACTTTA
TCTCTACCCACGGTGCTCGTAAGGGTCTGGCGGATACTGCACTTAAGACAGCGAACTCCGGTTACCTGACTCGTCGTCTG
GTGGATGTGGCCCAGGATCTGGTGATCATCGAAGACGATTGTGGCGCGACCGAAGGTCTGTCCATGAAGCCGCTGATTGA
AGGTGGTGACGTGGTTGAGCCGCTGCGTGAGCGCGTACTGGGTCGTGTAGTTGCTGAAGACGTTATGTACCCAGGTACCG
ACGAAGTGCTGGCACCTCGCAACACCCTGCTGGACGAAGCCTGGTGTGACAAGCTCGAACAGCACAGCGTTGACGAAGTA
CAGGTTCGCTCCGTAATTACCTGTGAAACCGACTTTGGTGTGTGTGCCAAGTGTTATGGGCGTGACTTGGCCCGTGGTCA
CATCATCAACATGGGTGAAGCCATCGGTGTGGTTGCAGCCCAGTCAATCGGTGAACCAGGTACACAGCTGACGATGCGTA
CGTTCCACATCGGTGGTGCGGCATCCCGAGCGTCTGCCGAAAACAGCGTACAGGTGAAGAACGCCGGTACTCTGAAGCTG
CACAATGCCAAGTACGTAACCAACAGCGACGGCAAACTGGTTATCGTGTCTCGTTCTTCTGAGCTGGCCATCATCGATGA
GCTGGGTCGTGAGAAAGAGCGCTACAAGGTGCCTTACGGTACCGTGCTTGACACCAAAGAAGGTGCCGAGGTGAATGCTG
GCCAGATCATTGCGAACTGGGATCCGCACACTCACCCAATCATCACTGAAGTGGCAGGTAGCATTAAGTTCGTAGACATG
ATTGACGGTGTAACCATTACCCGTCAGACCGACGAACTGACCGGTCTGTCTTCAATCGTCGTACTGGACGTGGGTCAGCG
TACCTCTGCCGGTAAAGAAATGCGTCCAGCAGTACGTCTGGTGGATGACAACGGCAACGACCTGACTATCCCAGGCACCG
ACGTTCCGGCGCAGTACTTCCTGCCTGGTAACGCGATTGTGAACCTGGACGACAACGCCAAGATCAGCGTGGGTGACGCC
CTGGCTCGTATTCCTCAGGAATCGTCCAAGACCCGCGACATCACCGGTGGTCTGCCACGGGTTGCTGACTTGTTCGAAGC
CCGTCGTCCAAAAGAGCCTGCTATTCTGGCCGAAATCAGCGGTACTATCTCCTTCGGTAAAGAAACCAAGGGTAAGCGCC
GTCTGGTTATCACCCCGAACGACGGTGGCGATGCTTACGAGGAAATGATTCCTAAGTGGCGTAACCTGAACGTGTTCGAA
GGTGAAAAGGTTGAGCGTGGTGAAGTTATCGCAGACGGTCCAGAGTCAGCCCATGACATTCTGCGCCTGCGTGGCATCCA
CAACGTGGCCAACTACATTGTGAACGAAGTACAGGACGTTTACCGTCTGCAGGGTGTGAAGATCAACGACAAGCACATCG
AGGTGATCATTCGCCAGATGCTGCGTAAGTGCATCATCACCCAGGCCGGTGACTCTGAGTTCCTGGAAGGTGAGCAGGTA
GAAGTAGCTCGCGTGAAGATTGCCAACCGCGATCTGGAAGCTGCCGGTAAGCAGCCAGCTAAGTTCGAACGCGAACTGCT
GGGTATTACCAAGGCATCTCTGGCGACTGAGTCCTTCATCTCTGCGGCCTCGTTCCAGGAAACCACTCGCGTTCTTACCG
AAGCGGCTGTTGGCGGTAAGTCCGACAACCTGCGCGGTCTGAAAGAGAACGTTATTGTGGGTCGTCTGATCCCTGCCGGT
ACCGGTTTTGCTTACCACAAGAATCGCGCCAAGGCGCGTGCTTCTGGTGAAGAAACTGCGGCTCCGACCATTACTGCCAG
CGAAGCTGAGCAGAACCTGGCGGATCTGCTGAATCTGGCCGGTAGCCAAGAGTAA

Upstream 100 bases:

>100_bases
CTGGATCAAGAGTAACAGGGCGCCAAGCGCGTTTGGCAATTAACACGGTGTCCCGTCTGCAGGGACGGGGCACCTGGTTT
AACTCCTTCAGGAGAGAAAC

Downstream 100 bases:

>100_bases
GTTACCACTCTGTAAAAAAGGCGCCTCCGGGCGCCTTTTTTGTATTCATAACGCGTCATTAGTTGGCTATTTCTTGACAG
TTTGCCTCGACCTTTCTAAA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1404; Mature: 1404

Protein sequence:

>1404_residues
MKDLLKFLKQQGKTEEFEGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESYVVIEPGMTSLERGQML
TEENYLDALEEYGDEFEAKMGAEAVLDLLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLIEAFYTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYISRERVNGRGEAMAFESVAEAEKAYRVGAAELHARVKVRITETIIGEN
GERTKQRRIVDTTVGRAILSQILPAGLSFDLVNQDMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFQYATISGASVG
INDMVIPEEKYSLVADAEAEVIEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSSETVINRHGEEEKQKSFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVIIEDDCGATEGLSMKPLIEGGDVVEPLRERVLGRVVAEDVMYPGTDEVLAPRNTLLDEAWCDKLEQHSVDEV
QVRSVITCETDFGVCAKCYGRDLARGHIINMGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENSVQVKNAGTLKL
HNAKYVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLDTKEGAEVNAGQIIANWDPHTHPIITEVAGSIKFVDM
IDGVTITRQTDELTGLSSIVVLDVGQRTSAGKEMRPAVRLVDDNGNDLTIPGTDVPAQYFLPGNAIVNLDDNAKISVGDA
LARIPQESSKTRDITGGLPRVADLFEARRPKEPAILAEISGTISFGKETKGKRRLVITPNDGGDAYEEMIPKWRNLNVFE
GEKVERGEVIADGPESAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCIITQAGDSEFLEGEQV
EVARVKIANRDLEAAGKQPAKFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAG
TGFAYHKNRAKARASGEETAAPTITASEAEQNLADLLNLAGSQE

Sequences:

>Translated_1404_residues
MKDLLKFLKQQGKTEEFEGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESYVVIEPGMTSLERGQML
TEENYLDALEEYGDEFEAKMGAEAVLDLLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLIEAFYTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYISRERVNGRGEAMAFESVAEAEKAYRVGAAELHARVKVRITETIIGEN
GERTKQRRIVDTTVGRAILSQILPAGLSFDLVNQDMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFQYATISGASVG
INDMVIPEEKYSLVADAEAEVIEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSSETVINRHGEEEKQKSFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVIIEDDCGATEGLSMKPLIEGGDVVEPLRERVLGRVVAEDVMYPGTDEVLAPRNTLLDEAWCDKLEQHSVDEV
QVRSVITCETDFGVCAKCYGRDLARGHIINMGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENSVQVKNAGTLKL
HNAKYVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLDTKEGAEVNAGQIIANWDPHTHPIITEVAGSIKFVDM
IDGVTITRQTDELTGLSSIVVLDVGQRTSAGKEMRPAVRLVDDNGNDLTIPGTDVPAQYFLPGNAIVNLDDNAKISVGDA
LARIPQESSKTRDITGGLPRVADLFEARRPKEPAILAEISGTISFGKETKGKRRLVITPNDGGDAYEEMIPKWRNLNVFE
GEKVERGEVIADGPESAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCIITQAGDSEFLEGEQV
EVARVKIANRDLEAAGKQPAKFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAG
TGFAYHKNRAKARASGEETAAPTITASEAEQNLADLLNLAGSQE
>Mature_1404_residues
MKDLLKFLKQQGKTEEFEGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESYVVIEPGMTSLERGQML
TEENYLDALEEYGDEFEAKMGAEAVLDLLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLIEAFYTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYISRERVNGRGEAMAFESVAEAEKAYRVGAAELHARVKVRITETIIGEN
GERTKQRRIVDTTVGRAILSQILPAGLSFDLVNQDMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFQYATISGASVG
INDMVIPEEKYSLVADAEAEVIEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSSETVINRHGEEEKQKSFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVIIEDDCGATEGLSMKPLIEGGDVVEPLRERVLGRVVAEDVMYPGTDEVLAPRNTLLDEAWCDKLEQHSVDEV
QVRSVITCETDFGVCAKCYGRDLARGHIINMGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENSVQVKNAGTLKL
HNAKYVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLDTKEGAEVNAGQIIANWDPHTHPIITEVAGSIKFVDM
IDGVTITRQTDELTGLSSIVVLDVGQRTSAGKEMRPAVRLVDDNGNDLTIPGTDVPAQYFLPGNAIVNLDDNAKISVGDA
LARIPQESSKTRDITGGLPRVADLFEARRPKEPAILAEISGTISFGKETKGKRRLVITPNDGGDAYEEMIPKWRNLNVFE
GEKVERGEVIADGPESAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCIITQAGDSEFLEGEQV
EVARVKIANRDLEAAGKQPAKFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAG
TGFAYHKNRAKARASGEETAAPTITASEAEQNLADLLNLAGSQE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=917, Percent_Identity=26.3904034896401, Blast_Score=203, Evalue=1e-51,
Organism=Homo sapiens, GI39725938, Length=932, Percent_Identity=25.9656652360515, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI103471997, Length=602, Percent_Identity=24.9169435215947, Blast_Score=113, Evalue=1e-24,
Organism=Escherichia coli, GI2367335, Length=1404, Percent_Identity=81.3390313390313, Blast_Score=2351, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=688, Percent_Identity=26.7441860465116, Blast_Score=183, Evalue=6e-46,
Organism=Caenorhabditis elegans, GI71987878, Length=923, Percent_Identity=24.2686890574215, Blast_Score=177, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=733, Percent_Identity=25.7844474761255, Blast_Score=174, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6320061, Length=893, Percent_Identity=24.3001119820829, Blast_Score=168, Evalue=7e-42,
Organism=Drosophila melanogaster, GI17530899, Length=918, Percent_Identity=24.6187363834423, Blast_Score=186, Evalue=1e-46,
Organism=Drosophila melanogaster, GI281360912, Length=872, Percent_Identity=23.7385321100917, Blast_Score=167, Evalue=4e-41,
Organism=Drosophila melanogaster, GI17647875, Length=361, Percent_Identity=27.7008310249307, Blast_Score=101, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 155273; Mature: 155273

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLKFLKQQGKTEEFEGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCAR
CHHHHHHHHHCCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLMLDMTLRDIERVLYFESYVVIEPGMTSLERGQMLTEENYLDALEEYGDEFEAKM
HHHHCHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GAEAVLDLLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLIEAFYTSGNKPEWMILK
CHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHP
EEECCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
CEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCHHH
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYISRERVNGRGEAMAFESVAEAEKAYRVG
HHHEEECCCCCCCCCCCEEEECCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCC
AAELHARVKVRITETIIGENGERTKQRRIVDTTVGRAILSQILPAGLSFDLVNQDMGKKQ
HHHHEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCHHH
ISKLLNTCYRQLGLKDTVIFADQLMYTGFQYATISGASVGINDMVIPEEKYSLVADAEAE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHCEEECCCHH
VIEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSSETVINRHGEEEKQKSFN
HHHHHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHHCCCCCHHHHCCCCHHHHHCCC
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVIIEDDCGATEGLSMKPLIEGGDVVEPLRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHH
GRVVAEDVMYPGTDEVLAPRNTLLDEAWCDKLEQHSVDEVQVRSVITCETDFGVCAKCYG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHC
RDLARGHIINMGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENSVQVKNAGTLKL
CHHHCCCEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCEEEE
HNAKYVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLDTKEGAEVNAGQIIANW
ECCEEEECCCCEEEEEECCCCEEHHHHHCCCHHHEECCCCCEEECCCCCCCCCCEEEECC
DPHTHPIITEVAGSIKFVDMIDGVTITRQTDELTGLSSIVVLDVGQRTSAGKEMRPAVRL
CCCCCHHHHHHCCCEEEEEHHCCEEEEECCHHHCCCCEEEEEECCCCCCCCCCCCCEEEE
VDDNGNDLTIPGTDVPAQYFLPGNAIVNLDDNAKISVGDALARIPQESSKTRDITGGLPR
EECCCCEEEECCCCCCCEEEECCCEEEECCCCCEEEHHHHHHHCCCCCCCCCCCCCCCHH
VADLFEARRPKEPAILAEISGTISFGKETKGKRRLVITPNDGGDAYEEMIPKWRNLNVFE
HHHHHHHCCCCCCEEEEEECCCEECCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCC
GEKVERGEVIADGPESAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQM
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKCIITQAGDSEFLEGEQVEVARVKIANRDLEAAGKQPAKFERELLGITKASLATESFI
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAGTGFAYHKNRAKARASGEETA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECCCCCCHHHCCCHHHHCCCCCCC
APTITASEAEQNLADLLNLAGSQE
CCCEEHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKDLLKFLKQQGKTEEFEGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCAR
CHHHHHHHHHCCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLMLDMTLRDIERVLYFESYVVIEPGMTSLERGQMLTEENYLDALEEYGDEFEAKM
HHHHCHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GAEAVLDLLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLIEAFYTSGNKPEWMILK
CHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHP
EEECCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
CEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCHHH
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYISRERVNGRGEAMAFESVAEAEKAYRVG
HHHEEECCCCCCCCCCCEEEECCCCCEEEEEEHHHHHCCCCCCHHHHHHHHHHHHHHHCC
AAELHARVKVRITETIIGENGERTKQRRIVDTTVGRAILSQILPAGLSFDLVNQDMGKKQ
HHHHEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCCHHH
ISKLLNTCYRQLGLKDTVIFADQLMYTGFQYATISGASVGINDMVIPEEKYSLVADAEAE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCHHHCEEECCCHH
VIEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSSETVINRHGEEEKQKSFN
HHHHHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHHCCCCCHHHHCCCCHHHHHCCC
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVIIEDDCGATEGLSMKPLIEGGDVVEPLRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHH
GRVVAEDVMYPGTDEVLAPRNTLLDEAWCDKLEQHSVDEVQVRSVITCETDFGVCAKCYG
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHC
RDLARGHIINMGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENSVQVKNAGTLKL
CHHHCCCEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCEEEE
HNAKYVTNSDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLDTKEGAEVNAGQIIANW
ECCEEEECCCCEEEEEECCCCEEHHHHHCCCHHHEECCCCCEEECCCCCCCCCCEEEECC
DPHTHPIITEVAGSIKFVDMIDGVTITRQTDELTGLSSIVVLDVGQRTSAGKEMRPAVRL
CCCCCHHHHHHCCCEEEEEHHCCEEEEECCHHHCCCCEEEEEECCCCCCCCCCCCCEEEE
VDDNGNDLTIPGTDVPAQYFLPGNAIVNLDDNAKISVGDALARIPQESSKTRDITGGLPR
EECCCCEEEECCCCCCCEEEECCCEEEECCCCCEEEHHHHHHHCCCCCCCCCCCCCCCHH
VADLFEARRPKEPAILAEISGTISFGKETKGKRRLVITPNDGGDAYEEMIPKWRNLNVFE
HHHHHHHCCCCCCEEEEEECCCEECCCCCCCCEEEEEECCCCCHHHHHHCCCCCCCCCCC
GEKVERGEVIADGPESAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQM
CCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKCIITQAGDSEFLEGEQVEVARVKIANRDLEAAGKQPAKFERELLGITKASLATESFI
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAGTGFAYHKNRAKARASGEETA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECCCCCCHHHCCCHHHHCCCCCCC
APTITASEAEQNLADLLNLAGSQE
CCCEEHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA