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The map label for this gene is atoS [H]

Identifier: 119773268

GI number: 119773268

Start: 139832

End: 141958

Strand: Direct

Name: atoS [H]

Synonym: Sama_0126

Alternate gene names: 119773268

Gene position: 139832-141958 (Clockwise)

Preceding gene: 119773267

Following gene: 119773271

Centisome position: 3.25

GC content: 54.82

Gene sequence:

>2127_bases
ATGTCCTTCTTCACCCAATTGTTTGGTGTTAACTGGCGCCAGATGCAGGCCAAGGTGCGCTACCGCATTCTTATTCTTAC
CTTGCTGCCAATTTTACTGACCCTGGTGAGCCTGGTATTTATCACCATCTACTGGAATATCAGCTACACCGGCCAGCAGT
TGTTTATGAAGGTAAAAGCCGACCTCACTGTGGCCAACAACACCCTCGAACAGGTGCAGCGGCGGCAGGAAAAGGAGCTG
GAGAACCTGCTCCGGTCGTGGGAGTTTCAAAACTTTTTCCGCGCTAACCACGGCGACAAACAGCAGCAGGCGGACGACTT
CAACGCGTTTCTGGCCGAGCGCCGTATTGCCATGGATTTGGACTTTTTACGGCTGATTAATGTTGAGCGTGCCGCGGCCG
ATCCTGACTTGCGTCATCTGCTGACCAAAGTAAAGGGTGGAGAGCCATTTACCGGCCTGATGGTGCTCTCATCAAAACGC
CTTGCCCGTCTGGATCCGGTATTGGCCGAGCGTGCCCGGTTGACACTCTTGCCCACTCCCCGCGCCGATGTGCCGGACAG
GGACGCTGAAGACAGGGGCATGCTGAGCCGAAGTCTGATGCCGATAGTGGATAGCGAGGGCGAGGTAGCCTGGTATCTGG
ATGGCGGCACCCTGCTGAATCGGGATACCCGTATTGTCGATCACATCCGTGACCTGGTGTACGACAAGGGTACACTGCCT
GAGCGCTCCATCGGCACTGTCACCATCTTTTTGGACAATGTGCGTATCAGCACCAACGTGCCGCTGCACTTCTTCCCCCG
GGATGGCGAAGACAAGGGGCGGGCGCTGGGCAGCCTGGTATCTGAAGAGGTTAAACACAAGGTGCTGACACAGGGCCAGA
CCTGGGTCGACAGAGCGTTTGTGTACAACGACTGGTTTATCTCTGCCTACGCGCCTCTAACCGACGTGCGTGGTGAGCGT
ATCGGCATGATATACACAGGCTTTTCTGAAGCGCCCTTTATCCATAACTATCTGCTTAACATCATAGAGCTGGGCACCAT
ACTCATGCTGGTGCTGCTGGTGTCCGGCATGCTGGTGTATCGGGGCGCTTACAGCCTGCTGCAGCCAATTGAACGGATCC
ATCATGTGGTAAAGGCGGTGCAGTCGGGCCGTAACGTACGCATCGGTGAATTGGGACTGGAGAAAGACAACGAGCTTGCC
AATCTGGCTGAGCAGTTTGACCGCATGCTCGACCTGCTGCAAAGGCGCAATGCCCAGATCCAGTCCGCCGCCGAGCAGCT
GGAATTAAAAGTGGAAGAGCGAACCCGCAGTCTGCAGGAAAAAACGGAAGAGCTGCAGCGTAACGTGTCGTTGCTGAACG
AGACCCGAGCTCAGCTGGTGACCAATGAAAAGCTCACAGCATTGGGTGAGCTTACAGCGGGTATTGCCCACGAAATTAAT
AATCCTACGGCGGTGATCCTCGGCAATATGGAGCTGCTGCGCTCTGAGCTTGGTGATAAGGCAGGACAGGTGGAGGAGGA
AATCGACCTGGTTATCCAACAAGTCGGCCGCATAAGCACCATTATTCGCAGCCTGCTGCAGTACAGCCGCCCCGGCGAAT
TTAACGCACCGCTTGAGATGCACCAGATAACCCCCATCATCGAAGAAATGCTGGTATTGGTGCGCCACTCCATCAAGAAG
CAGGAAGTGGTTCTTCATCAGGAGCTTAATGCCAGTTGTCCGGTACAAATCAACCGACCGCAATTATTGCAGGTCTTGAT
TAACCTGGTGGTTAACGCGGCCCATGCAATGGATGGGAAGGGGCGGATTTGGATCCGTACCTACGACTGGGTGGTGCAGG
ATGAGCCGGTTGGGGTCAAGATTGAAATCGAAGACGAGGGTTGTGGTATCGCTCCCGAGCAGCTTGGCCGTATCTTTGAC
CCTTTTTACACCACGCGTCCGGATGGCACGGGTTTGGGATTGTCTTTGAGCTACGGCATCATCAAACGGATTGGCGGCAC
CATAGAAGTCACTTCCACCCTGGGCAAAGGCACCCTGTTTACCATTGGTCTGTACCATGAAGCACGGGAAGAGAGTGGCT
TGAATCCCTACGAAGGTTTGATGCTGGGCGCCGGAGGTTTGGCTTAA

Upstream 100 bases:

>100_bases
ATAAGTCGGCAGCAGCCCGTGATTTGGGCGTATCCCGCAAGACCCTGGATCGAAAATTCAAAGAGTGGTTTGGCACTGAC
AGTGACGAGGAAGAATAACC

Downstream 100 bases:

>100_bases
AAACAATAGGGCAAAAAAAAGCCGGACGTTGGGTCCGGCCACAAAAGTGTGTGAGCAATGTCGTGCATGTTAACTCGGAG
GCACCGACCCACTTGCAGAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 707

Protein sequence:

>708_residues
MSFFTQLFGVNWRQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGQQLFMKVKADLTVANNTLEQVQRRQEKEL
ENLLRSWEFQNFFRANHGDKQQQADDFNAFLAERRIAMDLDFLRLINVERAAADPDLRHLLTKVKGGEPFTGLMVLSSKR
LARLDPVLAERARLTLLPTPRADVPDRDAEDRGMLSRSLMPIVDSEGEVAWYLDGGTLLNRDTRIVDHIRDLVYDKGTLP
ERSIGTVTIFLDNVRISTNVPLHFFPRDGEDKGRALGSLVSEEVKHKVLTQGQTWVDRAFVYNDWFISAYAPLTDVRGER
IGMIYTGFSEAPFIHNYLLNIIELGTILMLVLLVSGMLVYRGAYSLLQPIERIHHVVKAVQSGRNVRIGELGLEKDNELA
NLAEQFDRMLDLLQRRNAQIQSAAEQLELKVEERTRSLQEKTEELQRNVSLLNETRAQLVTNEKLTALGELTAGIAHEIN
NPTAVILGNMELLRSELGDKAGQVEEEIDLVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIKK
QEVVLHQELNASCPVQINRPQLLQVLINLVVNAAHAMDGKGRIWIRTYDWVVQDEPVGVKIEIEDEGCGIAPEQLGRIFD
PFYTTRPDGTGLGLSLSYGIIKRIGGTIEVTSTLGKGTLFTIGLYHEAREESGLNPYEGLMLGAGGLA

Sequences:

>Translated_708_residues
MSFFTQLFGVNWRQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGQQLFMKVKADLTVANNTLEQVQRRQEKEL
ENLLRSWEFQNFFRANHGDKQQQADDFNAFLAERRIAMDLDFLRLINVERAAADPDLRHLLTKVKGGEPFTGLMVLSSKR
LARLDPVLAERARLTLLPTPRADVPDRDAEDRGMLSRSLMPIVDSEGEVAWYLDGGTLLNRDTRIVDHIRDLVYDKGTLP
ERSIGTVTIFLDNVRISTNVPLHFFPRDGEDKGRALGSLVSEEVKHKVLTQGQTWVDRAFVYNDWFISAYAPLTDVRGER
IGMIYTGFSEAPFIHNYLLNIIELGTILMLVLLVSGMLVYRGAYSLLQPIERIHHVVKAVQSGRNVRIGELGLEKDNELA
NLAEQFDRMLDLLQRRNAQIQSAAEQLELKVEERTRSLQEKTEELQRNVSLLNETRAQLVTNEKLTALGELTAGIAHEIN
NPTAVILGNMELLRSELGDKAGQVEEEIDLVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIKK
QEVVLHQELNASCPVQINRPQLLQVLINLVVNAAHAMDGKGRIWIRTYDWVVQDEPVGVKIEIEDEGCGIAPEQLGRIFD
PFYTTRPDGTGLGLSLSYGIIKRIGGTIEVTSTLGKGTLFTIGLYHEAREESGLNPYEGLMLGAGGLA
>Mature_707_residues
SFFTQLFGVNWRQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGQQLFMKVKADLTVANNTLEQVQRRQEKELE
NLLRSWEFQNFFRANHGDKQQQADDFNAFLAERRIAMDLDFLRLINVERAAADPDLRHLLTKVKGGEPFTGLMVLSSKRL
ARLDPVLAERARLTLLPTPRADVPDRDAEDRGMLSRSLMPIVDSEGEVAWYLDGGTLLNRDTRIVDHIRDLVYDKGTLPE
RSIGTVTIFLDNVRISTNVPLHFFPRDGEDKGRALGSLVSEEVKHKVLTQGQTWVDRAFVYNDWFISAYAPLTDVRGERI
GMIYTGFSEAPFIHNYLLNIIELGTILMLVLLVSGMLVYRGAYSLLQPIERIHHVVKAVQSGRNVRIGELGLEKDNELAN
LAEQFDRMLDLLQRRNAQIQSAAEQLELKVEERTRSLQEKTEELQRNVSLLNETRAQLVTNEKLTALGELTAGIAHEINN
PTAVILGNMELLRSELGDKAGQVEEEIDLVIQQVGRISTIIRSLLQYSRPGEFNAPLEMHQITPIIEEMLVLVRHSIKKQ
EVVLHQELNASCPVQINRPQLLQVLINLVVNAAHAMDGKGRIWIRTYDWVVQDEPVGVKIEIEDEGCGIAPEQLGRIFDP
FYTTRPDGTGLGLSLSYGIIKRIGGTIEVTSTLGKGTLFTIGLYHEAREESGLNPYEGLMLGAGGLA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=37.8260869565217, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI1790436, Length=224, Percent_Identity=35.2678571428571, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081816, Length=290, Percent_Identity=28.6206896551724, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1790300, Length=222, Percent_Identity=31.981981981982, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1786600, Length=221, Percent_Identity=28.0542986425339, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1789808, Length=209, Percent_Identity=27.7511961722488, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082128, Length=219, Percent_Identity=26.4840182648402, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=279, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=26.8398268398268, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=460, Percent_Identity=21.304347826087, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI48994928, Length=227, Percent_Identity=27.7533039647577, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79973; Mature: 79842

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFTQLFGVNWRQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGQQLFMKVKA
CCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHH
DLTVANNTLEQVQRRQEKELENLLRSWEFQNFFRANHGDKQQQADDFNAFLAERRIAMDL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
DFLRLINVERAAADPDLRHLLTKVKGGEPFTGLMVLSSKRLARLDPVLAERARLTLLPTP
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEHEEECCCHHHHHCHHHHHCCCEEEECCC
RADVPDRDAEDRGMLSRSLMPIVDSEGEVAWYLDGGTLLNRDTRIVDHIRDLVYDKGTLP
CCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCC
ERSIGTVTIFLDNVRISTNVPLHFFPRDGEDKGRALGSLVSEEVKHKVLTQGQTWVDRAF
CCCCCEEEEEEECEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VYNDWFISAYAPLTDVRGERIGMIYTGFSEAPFIHNYLLNIIELGTILMLVLLVSGMLVY
EEECCEEEECCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGAYSLLQPIERIHHVVKAVQSGRNVRIGELGLEKDNELANLAEQFDRMLDLLQRRNAQI
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
QSAAEQLELKVEERTRSLQEKTEELQRNVSLLNETRAQLVTNEKLTALGELTAGIAHEIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
NPTAVILGNMELLRSELGDKAGQVEEEIDLVIQQVGRISTIIRSLLQYSRPGEFNAPLEM
CCEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
HQITPIIEEMLVLVRHSIKKQEVVLHQELNASCPVQINRPQLLQVLINLVVNAAHAMDGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCC
GRIWIRTYDWVVQDEPVGVKIEIEDEGCGIAPEQLGRIFDPFYTTRPDGTGLGLSLSYGI
CEEEEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEHHHHH
IKRIGGTIEVTSTLGKGTLFTIGLYHEAREESGLNPYEGLMLGAGGLA
HHHCCCCEEEEECCCCCCEEEEEEHHHHHHHCCCCHHHCEEECCCCCC
>Mature Secondary Structure 
SFFTQLFGVNWRQMQAKVRYRILILTLLPILLTLVSLVFITIYWNISYTGQQLFMKVKA
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEECHHHHHHHHHH
DLTVANNTLEQVQRRQEKELENLLRSWEFQNFFRANHGDKQQQADDFNAFLAERRIAMDL
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
DFLRLINVERAAADPDLRHLLTKVKGGEPFTGLMVLSSKRLARLDPVLAERARLTLLPTP
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEHEEECCCHHHHHCHHHHHCCCEEEECCC
RADVPDRDAEDRGMLSRSLMPIVDSEGEVAWYLDGGTLLNRDTRIVDHIRDLVYDKGTLP
CCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCC
ERSIGTVTIFLDNVRISTNVPLHFFPRDGEDKGRALGSLVSEEVKHKVLTQGQTWVDRAF
CCCCCEEEEEEECEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
VYNDWFISAYAPLTDVRGERIGMIYTGFSEAPFIHNYLLNIIELGTILMLVLLVSGMLVY
EEECCEEEECCCHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGAYSLLQPIERIHHVVKAVQSGRNVRIGELGLEKDNELANLAEQFDRMLDLLQRRNAQI
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHH
QSAAEQLELKVEERTRSLQEKTEELQRNVSLLNETRAQLVTNEKLTALGELTAGIAHEIN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
NPTAVILGNMELLRSELGDKAGQVEEEIDLVIQQVGRISTIIRSLLQYSRPGEFNAPLEM
CCEEEEECCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHH
HQITPIIEEMLVLVRHSIKKQEVVLHQELNASCPVQINRPQLLQVLINLVVNAAHAMDGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHCCCC
GRIWIRTYDWVVQDEPVGVKIEIEDEGCGIAPEQLGRIFDPFYTTRPDGTGLGLSLSYGI
CEEEEEEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEHHHHH
IKRIGGTIEVTSTLGKGTLFTIGLYHEAREESGLNPYEGLMLGAGGLA
HHHCCCCEEEEECCCCCCEEEEEEHHHHHHHCCCCHHHCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]