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The map label for this gene is glpG [H]

Identifier: 119773237

GI number: 119773237

Start: 108523

End: 109353

Strand: Reverse

Name: glpG [H]

Synonym: Sama_0095

Alternate gene names: 119773237

Gene position: 109353-108523 (Counterclockwise)

Preceding gene: 119773238

Following gene: 119773235

Centisome position: 2.54

GC content: 53.91

Gene sequence:

>831_bases
ATGGAGTTCGGCCGACTGCCCAACGCCAGAGCAGCTCAGGCCCTGGCGGATTATCTCAAAAGCCGGGGGATAGAATGCCT
AATCAGCCCGGTAGCAGAGGGCGTGAGCCTGTCGGTGGTCAAGCCACAGGATCTGGCTGCTGCCAAGGCCGAATTCGATT
ACTTTCTGCGTCATCCGGGTGATGATAAATACCTGGCGGCATCATGGGAAACCGGCAATACAGAAACTCAATTTAACTAT
GGTTCACCGGGACTTGCGCTGCTGAGCCGCTTTGTGACTGCCGCCGGACCCATTACGCTCACTGTATTCGCATTCTGTAT
TCTGGTGTATACGGCTTTTAATCTGGGCTTTGCCGAACAGACATATTCACTGCTGAGTTTTTTTGGCGCCCACGGCACCG
ACCAAAGCTCCGAAGTGTGGCGAATCTTCACCCCGACGCTGATGCATTTTTCGCTGATGCATATCAGCTTTAATCTCTTG
TGGTGGTGGTATCTGGGCGGAAAGATTGAAACCCGTATCGGCTCCTGGCCGCTGATGACATTGCTGCTTGTGGCAGGCAC
CCTGCCCAACCTCATTCAGTATTATGTTTCGGGCCCTAACTTTGGCGGTTTGTCCGGTGTTGTGTATGCCGTCGCAGGCT
ACACCTTTGTGATGGGTATCAGAAAGCCCTCTGCCGGTATCTATCTGCCACCAAGCTATATGGGCTTTATGCTGGTTTGG
CTGATATTGGGCTTCTTTGATGTTCTCGGACTTTCCATGGCCAATGGCGCCCACCTGGGTGGACTCGCAGTGGGTCTGCT
GCAGGGGTTATGGGACAGTCGCCGCCGCTAA

Upstream 100 bases:

>100_bases
TCAGCAGCCAGAATGCCGCTGCCTATCTGGTGGAGCAGGGTTTCGATCAGGTGTTCAGCCTCGATGGCGGTTATAGCGCC
TGGCATATGGCCAATCTCTG

Downstream 100 bases:

>100_bases
GGTTCCAGCTCGACGGCGACAACTGCAGACCCGTCAGGCCATCGCCAGTACTTTGTTGACCAGCTTTTCGATGCCGGAAT
GCGCCTCGGCGATGTTGCCT

Product: glpG protein

Products: NA

Alternate protein names: Intramembrane serine protease [H]

Number of amino acids: Translated: 276; Mature: 276

Protein sequence:

>276_residues
MEFGRLPNARAAQALADYLKSRGIECLISPVAEGVSLSVVKPQDLAAAKAEFDYFLRHPGDDKYLAASWETGNTETQFNY
GSPGLALLSRFVTAAGPITLTVFAFCILVYTAFNLGFAEQTYSLLSFFGAHGTDQSSEVWRIFTPTLMHFSLMHISFNLL
WWWYLGGKIETRIGSWPLMTLLLVAGTLPNLIQYYVSGPNFGGLSGVVYAVAGYTFVMGIRKPSAGIYLPPSYMGFMLVW
LILGFFDVLGLSMANGAHLGGLAVGLLQGLWDSRRR

Sequences:

>Translated_276_residues
MEFGRLPNARAAQALADYLKSRGIECLISPVAEGVSLSVVKPQDLAAAKAEFDYFLRHPGDDKYLAASWETGNTETQFNY
GSPGLALLSRFVTAAGPITLTVFAFCILVYTAFNLGFAEQTYSLLSFFGAHGTDQSSEVWRIFTPTLMHFSLMHISFNLL
WWWYLGGKIETRIGSWPLMTLLLVAGTLPNLIQYYVSGPNFGGLSGVVYAVAGYTFVMGIRKPSAGIYLPPSYMGFMLVW
LILGFFDVLGLSMANGAHLGGLAVGLLQGLWDSRRR
>Mature_276_residues
MEFGRLPNARAAQALADYLKSRGIECLISPVAEGVSLSVVKPQDLAAAKAEFDYFLRHPGDDKYLAASWETGNTETQFNY
GSPGLALLSRFVTAAGPITLTVFAFCILVYTAFNLGFAEQTYSLLSFFGAHGTDQSSEVWRIFTPTLMHFSLMHISFNLL
WWWYLGGKIETRIGSWPLMTLLLVAGTLPNLIQYYVSGPNFGGLSGVVYAVAGYTFVMGIRKPSAGIYLPPSYMGFMLVW
LILGFFDVLGLSMANGAHLGGLAVGLLQGLWDSRRR

Specific function: Rhomboid-type serine protease that catalyzes intramembrane proteolysis [H]

COG id: COG0705

COG function: function code R; Uncharacterized membrane protein (homolog of Drosophila rhomboid)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S54 family [H]

Homologues:

Organism=Escherichia coli, GI48994938, Length=273, Percent_Identity=41.7582417582418, Blast_Score=203, Evalue=8e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022732
- InterPro:   IPR002610
- InterPro:   IPR022764 [H]

Pfam domain/function: PF12122 DUF3582; PF01694 Rhomboid [H]

EC number: =3.4.21.105 [H]

Molecular weight: Translated: 30283; Mature: 30283

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFGRLPNARAAQALADYLKSRGIECLISPVAEGVSLSVVKPQDLAAAKAEFDYFLRHPG
CCCCCCCCHHHHHHHHHHHHHCCHHEEHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCC
DDKYLAASWETGNTETQFNYGSPGLALLSRFVTAAGPITLTVFAFCILVYTAFNLGFAEQ
CCCEEEEEECCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHH
TYSLLSFFGAHGTDQSSEVWRIFTPTLMHFSLMHISFNLLWWWYLGGKIETRIGSWPLMT
HHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCCHHHHH
LLLVAGTLPNLIQYYVSGPNFGGLSGVVYAVAGYTFVMGIRKPSAGIYLPPSYMGFMLVW
HHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCCCCEEECHHHHHHHHHH
LILGFFDVLGLSMANGAHLGGLAVGLLQGLWDSRRR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEFGRLPNARAAQALADYLKSRGIECLISPVAEGVSLSVVKPQDLAAAKAEFDYFLRHPG
CCCCCCCCHHHHHHHHHHHHHCCHHEEHHHHHCCCEEEEECCHHHHHHHHHHHHHHCCCC
DDKYLAASWETGNTETQFNYGSPGLALLSRFVTAAGPITLTVFAFCILVYTAFNLGFAEQ
CCCEEEEEECCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHH
TYSLLSFFGAHGTDQSSEVWRIFTPTLMHFSLMHISFNLLWWWYLGGKIETRIGSWPLMT
HHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHEEEEECCEEEECCCCHHHHH
LLLVAGTLPNLIQYYVSGPNFGGLSGVVYAVAGYTFVMGIRKPSAGIYLPPSYMGFMLVW
HHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEECCCCCCEEECHHHHHHHHHH
LILGFFDVLGLSMANGAHLGGLAVGLLQGLWDSRRR
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA