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The map label for this gene is pbpG [H]

Identifier: 119773214

GI number: 119773214

Start: 77895

End: 78806

Strand: Reverse

Name: pbpG [H]

Synonym: Sama_0072

Alternate gene names: 119773214

Gene position: 78806-77895 (Counterclockwise)

Preceding gene: 119773215

Following gene: 119773213

Centisome position: 1.83

GC content: 53.51

Gene sequence:

>912_bases
ATGAAATCCAAATTGTTCAAGTACATCAGCCCTCTGCTGATGCTCGGCCTGCTCTCGGCGACCAGTGCTCAGGGCGCGGT
AAAATCAGACGCCAAACCCACTCAGGAACTGGCTTCATACAGTGCACTCCTGGTCGATACCAAAACCAACGAAGTGCTCT
ATGCCAGTAACCCCCATCAGGTTGTTCCTATTGCCTCGATCTCCAAGCTGATGACTGCCATGGTGACCCTGGATGCCAAG
CTCCCGCTCGGGGAAAAAATCGCGGTTGAAGTCAAAGACAACCCCGAGATGAAAAACGTCGTTTCCCGCATCCGGCTTGG
CAGCACCCTGAGCCGTAAAGAAGCCATGTTGCTCACCCTGATGTCGTCGGAAAACCGCGCCGCCACCACCCTTGCCCATC
ATTACCCCGGAGGATATCAGGCCTTTGTGAAGGCGATGAATGCCAAGGCCAAGGCATTGGGTATGACCAACACCCGCTTT
GTTGAGCCCACAGGATTGTCGGTACACAACGTGTCTACCGCCGCCGATTTGGTGAAGCTGCTCAAGGCCGCGCAGGATTA
CCCTCTACTGGGCCAGCTCTCTTCGACACCAAGTAAGTCGGTAACCTTTGGCAAACCCAGATACAGTTTGGCGTTTTACA
ACACCAACCGACTGGTCAACAAAGACAATTGGGACATTCGCTTAACCAAAACCGGTTTCACCGATGCCGCCGGACACTGC
CTGGTGATGTTGACCAAGATGGCCAAACGGGATGTGGCCTTTGTGGTGCTCGACTCTTTCGGTAAACAAACCCACCTCGG
CGATGCCGGACGCCTGAAAAAATGGCTCGAAACCGGTAAAGTCAGCCCACTGCCTGACTCCGCCAAAACTTATAAAGAAC
AACGCAAGCGTGAGCGTAATAACAAGGCATAA

Upstream 100 bases:

>100_bases
AGCGAACCTTGACGGCTTGTGATTGTCTCACCCTTGATTACACTTGAGGTATTGCCGCGCAGACGGCAAGCAAACAATCA
CTTTATCATTGGCATTGCGC

Downstream 100 bases:

>100_bases
CATGGATGCTGTGATCCACGATAAAACCAATCAGGTATTTTTATTAGCGGCCAACGGCGTGGAAGCCAGGCTGGAGTACC
ACCGCCAGGGTGACTGTATC

Product: D-alanyl-D-alanine endopeptidase

Products: NA

Alternate protein names: DD-endopeptidase; Penicillin-binding protein 7; PBP-7 [H]

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKSKLFKYISPLLMLGLLSATSAQGAVKSDAKPTQELASYSALLVDTKTNEVLYASNPHQVVPIASISKLMTAMVTLDAK
LPLGEKIAVEVKDNPEMKNVVSRIRLGSTLSRKEAMLLTLMSSENRAATTLAHHYPGGYQAFVKAMNAKAKALGMTNTRF
VEPTGLSVHNVSTAADLVKLLKAAQDYPLLGQLSSTPSKSVTFGKPRYSLAFYNTNRLVNKDNWDIRLTKTGFTDAAGHC
LVMLTKMAKRDVAFVVLDSFGKQTHLGDAGRLKKWLETGKVSPLPDSAKTYKEQRKRERNNKA

Sequences:

>Translated_303_residues
MKSKLFKYISPLLMLGLLSATSAQGAVKSDAKPTQELASYSALLVDTKTNEVLYASNPHQVVPIASISKLMTAMVTLDAK
LPLGEKIAVEVKDNPEMKNVVSRIRLGSTLSRKEAMLLTLMSSENRAATTLAHHYPGGYQAFVKAMNAKAKALGMTNTRF
VEPTGLSVHNVSTAADLVKLLKAAQDYPLLGQLSSTPSKSVTFGKPRYSLAFYNTNRLVNKDNWDIRLTKTGFTDAAGHC
LVMLTKMAKRDVAFVVLDSFGKQTHLGDAGRLKKWLETGKVSPLPDSAKTYKEQRKRERNNKA
>Mature_303_residues
MKSKLFKYISPLLMLGLLSATSAQGAVKSDAKPTQELASYSALLVDTKTNEVLYASNPHQVVPIASISKLMTAMVTLDAK
LPLGEKIAVEVKDNPEMKNVVSRIRLGSTLSRKEAMLLTLMSSENRAATTLAHHYPGGYQAFVKAMNAKAKALGMTNTRF
VEPTGLSVHNVSTAADLVKLLKAAQDYPLLGQLSSTPSKSVTFGKPRYSLAFYNTNRLVNKDNWDIRLTKTGFTDAAGHC
LVMLTKMAKRDVAFVVLDSFGKQTHLGDAGRLKKWLETGKVSPLPDSAKTYKEQRKRERNNKA

Specific function: Cell wall formation. May play a specialized role in remodeling the cell wall. Specifically hydrolyze the DD- diaminopimelate-alanine bonds in high-molecular-mass murein sacculi [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI87082054, Length=256, Percent_Identity=65.625, Blast_Score=357, Evalue=1e-100,
Organism=Escherichia coli, GI1787062, Length=296, Percent_Identity=29.3918918918919, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082022, Length=286, Percent_Identity=27.6223776223776, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR018044
- InterPro:   IPR001967 [H]

Pfam domain/function: PF00768 Peptidase_S11 [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 33162; Mature: 33162

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKLFKYISPLLMLGLLSATSAQGAVKSDAKPTQELASYSALLVDTKTNEVLYASNPHQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEECCCCC
VVPIASISKLMTAMVTLDAKLPLGEKIAVEVKDNPEMKNVVSRIRLGSTLSRKEAMLLTL
EEEHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHEEEEEE
MSSENRAATTLAHHYPGGYQAFVKAMNAKAKALGMTNTRFVEPTGLSVHNVSTAADLVKL
ECCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCCEEECCCCCEEECHHHHHHHHHH
LKAAQDYPLLGQLSSTPSKSVTFGKPRYSLAFYNTNRLVNKDNWDIRLTKTGFTDAAGHC
HHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCEEECCCCCEEEEEECCCCCHHHHH
LVMLTKMAKRDVAFVVLDSFGKQTHLGDAGRLKKWLETGKVSPLPDSAKTYKEQRKRERN
HHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
NKA
CCC
>Mature Secondary Structure
MKSKLFKYISPLLMLGLLSATSAQGAVKSDAKPTQELASYSALLVDTKTNEVLYASNPHQ
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEECCCCC
VVPIASISKLMTAMVTLDAKLPLGEKIAVEVKDNPEMKNVVSRIRLGSTLSRKEAMLLTL
EEEHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCHHHHHEEEEEE
MSSENRAATTLAHHYPGGYQAFVKAMNAKAKALGMTNTRFVEPTGLSVHNVSTAADLVKL
ECCCCCHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCCCEEECCCCCEEECHHHHHHHHHH
LKAAQDYPLLGQLSSTPSKSVTFGKPRYSLAFYNTNRLVNKDNWDIRLTKTGFTDAAGHC
HHHHCCCCCCCCCCCCCCCCEEECCCCEEEEEEECCEEECCCCCEEEEEECCCCCHHHHH
LVMLTKMAKRDVAFVVLDSFGKQTHLGDAGRLKKWLETGKVSPLPDSAKTYKEQRKRERN
HHHHHHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
NKA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 6386470; 7721700; 7925376 [H]