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The map label for this gene is helD [H]

Identifier: 119718750

GI number: 119718750

Start: 4793196

End: 4795376

Strand: Reverse

Name: helD [H]

Synonym: Noca_4531

Alternate gene names: 119718750

Gene position: 4795376-4793196 (Counterclockwise)

Preceding gene: 119718751

Following gene: 119718749

Centisome position: 96.18

GC content: 74.28

Gene sequence:

>2181_bases
TTGTCCGAAGAGCTGGTCGAGCGGGAGATCGCTGCTGAGCAGGCGTTCGTCGACCGGGTGTACGTCCAGCTGGCCGAGTC
GGCCCGGCAGGCGCAGGCACTGGCCAAGGAGGGTCACAGTCGCGGCCGGCTGGGCCACGAGGGCGGGCTGGTCGAGCGGG
ACGCGATGGTGTTCCAGGCCGCCCGCCGGATCGCGCAGCTCGACGCCGCGCACGAGGGCCTGGTGTTCGGGCGCCTGGAC
ATGACCGCCGAGGTCGACCCGGAGCCGCGGTACGTCGGGCGAATCGGCCTGCGCGACGCCAACCGCGACTCCCTGCTCAT
CGACTGGCGGGCCCCCGCGGCCGCGGTGTTCTACCAGGCGACCGCGGCCGAGCCGCACGACGTCGTACGCCGCCGGGTGC
TGCGCTGCGCCGGCCCGCAGGTCGTCGGCGTGGAGGACGAGCTGCTGGACGCCGCGGCCGAGACCAGCCTGCCGATCGTC
GGTGAGGGCGCGTTGATGGCGCAGCTCTCCCGTGCGCGGGACCGCTCGATGCACTCGATCGTCGCGACCATCCAGGCCGA
GCAGGACCGGGCGATCCGGGCGCCCGGCAAGGGGGTCGTCTCGATCTCCGGCGGCCCCGGCACCGGCAAGACCGTCGTCG
CGCTGCACCGGGCGGCGTACCTGCTCTACAACGACCGTCGGCGCTACGAGGGCGGCGGCGTCCTGATCGTCGGCCCCAGC
GGGGTCTTCATGCGCTACATCGAGCGGGTGCTCCCGAGCCTCGGCGAGACCGCGGTGGCGCTGCGCTCGCTGGGCGAGGT
CGTCGACGGCGTGCGCGCCACCCGCCACGACGAGCCGACGGTCGCCGACGTCAAGGGCTCGGCGCGGATGGCCGAGCTGA
TGCGTCGTACGGCGCGCCAGCAGGCGCCGGGCAGCCCCCGGGAGTTCCGGATCTTCTGGCGCGACGACACCATCGTGCTC
GACCGCGGCGAGCTGGGCCGGCTGCGCCGCCAGCTGATGTCCCAGGGCCGGCGCAACCGACAGCTGCCCCGCGTGGCCCA
CGCCCTGCTCGACGCGATGTGGCGCCAGGTCCGCGGCGAGCGCGGGCGGGACCGCGGCCGCGAGTCCTTCGACGACGAGA
TGCTGTCGAACCAGTCGTTCGTCGACTTCGCCGCCGCCTGGTGGCCGCCGCTCGACGCCCTCGAGGTGTTCGGTTGGCTG
CGCGACCCCGAGCTGCTCTCCCGCGTCGGCGACGGGGTGGTGACCCCGGAGGAGCAGCGGCTGCTGGCCAAGTCGTGGGG
CGAGGCGGTCGGCCTCTCGGTCGAGGACGTCCCGCTGCTCGACGAGCTGCGCTACGCCCTCGGCGATGTCCCCGCCCGCA
CCGACGACGAGCACGAGCTCGACGACACGGGGCTGCTCGAGGGCGGGGTCGACATGCAGGAGCTGTTCACCGCGGCCGAC
CGCGAGTACGCCCCGTCCGGCCGGGCCTGGGCCCCGCCCACCCACCGCATCGACGACGACCCGTTCGCGCACGTGCTGGT
CGACGAGGCCCAGGACCTCACCCCCATGCAGTGGCGGATGGTCGGCCGGCGCGGCCGGGCGGCATCGTGGACGATCGTCG
GCGACCCCGCCCAGTCCTCCTGGCCGGTGCCGGCCGAGTCGGCCGCCGCGCGGGCGGGCGCGCTCGAGGGCAAGGAGGTC
CACGAGTTCCACCTCTCGACCAACTACCGCAACTCCTCGGAGATCTACGCCCACGCGGCGGCGTACGCCGAGCGGGTCGG
CCTGGACGCCGACCTGCCGACCGCGGTGCGGTCGACCGGCGTCGAGCCGACCGTCCTGGCCGGCATCGCCGACCTGGAGT
CCGCGACCCGTGAGGCCGTGGTGCAGATGGCGGCCGCGGTCGAGGGCACCGTGGGCATCGTGGTCCCGGTGGCACGTCGC
TCGGAGGTCAACGCCTGGTTGGCGTCCTGGCCCGAGGTCGCCGACGACGCGCCCGGCTCCCGGGCGGCCGTGGACTCCTC
GGTCGCCCCGTCCGGCGACGACCGGATCGTCGTGCTCACCGGCCTGGACACCAAGGGCCTGGAGTTCGACGGCATCGTCG
TCGTACGACCGCAGGAGATCGAGGACGAGTCGGCCACTGGCCGGGCCACGCTGTACGTCGTCCTCACCCGCGCCACCCAG
CTGCTGACCACGCTGTCCTGA

Upstream 100 bases:

>100_bases
GGTGGAGAGCAACGGGTAGGCTTGTCGACTTGCCGGAATCACCGGGCTCATCGGGTGGGTACGGCAGTGGGGACGTTTTC
CGGGTGAGGGGAAGCACGAG

Downstream 100 bases:

>100_bases
TCTCCCGCCGGCCGCGTGACCTTCGCCTCTGGCCCACTCGCACGGCGCGGCGTGGACTGAGGCCGACGGTCTGATCAGCG
CGGTGGCGCCCCGAGCGCCC

Product: putative helicase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MSEELVEREIAAEQAFVDRVYVQLAESARQAQALAKEGHSRGRLGHEGGLVERDAMVFQAARRIAQLDAAHEGLVFGRLD
MTAEVDPEPRYVGRIGLRDANRDSLLIDWRAPAAAVFYQATAAEPHDVVRRRVLRCAGPQVVGVEDELLDAAAETSLPIV
GEGALMAQLSRARDRSMHSIVATIQAEQDRAIRAPGKGVVSISGGPGTGKTVVALHRAAYLLYNDRRRYEGGGVLIVGPS
GVFMRYIERVLPSLGETAVALRSLGEVVDGVRATRHDEPTVADVKGSARMAELMRRTARQQAPGSPREFRIFWRDDTIVL
DRGELGRLRRQLMSQGRRNRQLPRVAHALLDAMWRQVRGERGRDRGRESFDDEMLSNQSFVDFAAAWWPPLDALEVFGWL
RDPELLSRVGDGVVTPEEQRLLAKSWGEAVGLSVEDVPLLDELRYALGDVPARTDDEHELDDTGLLEGGVDMQELFTAAD
REYAPSGRAWAPPTHRIDDDPFAHVLVDEAQDLTPMQWRMVGRRGRAASWTIVGDPAQSSWPVPAESAAARAGALEGKEV
HEFHLSTNYRNSSEIYAHAAAYAERVGLDADLPTAVRSTGVEPTVLAGIADLESATREAVVQMAAAVEGTVGIVVPVARR
SEVNAWLASWPEVADDAPGSRAAVDSSVAPSGDDRIVVLTGLDTKGLEFDGIVVVRPQEIEDESATGRATLYVVLTRATQ
LLTTLS

Sequences:

>Translated_726_residues
MSEELVEREIAAEQAFVDRVYVQLAESARQAQALAKEGHSRGRLGHEGGLVERDAMVFQAARRIAQLDAAHEGLVFGRLD
MTAEVDPEPRYVGRIGLRDANRDSLLIDWRAPAAAVFYQATAAEPHDVVRRRVLRCAGPQVVGVEDELLDAAAETSLPIV
GEGALMAQLSRARDRSMHSIVATIQAEQDRAIRAPGKGVVSISGGPGTGKTVVALHRAAYLLYNDRRRYEGGGVLIVGPS
GVFMRYIERVLPSLGETAVALRSLGEVVDGVRATRHDEPTVADVKGSARMAELMRRTARQQAPGSPREFRIFWRDDTIVL
DRGELGRLRRQLMSQGRRNRQLPRVAHALLDAMWRQVRGERGRDRGRESFDDEMLSNQSFVDFAAAWWPPLDALEVFGWL
RDPELLSRVGDGVVTPEEQRLLAKSWGEAVGLSVEDVPLLDELRYALGDVPARTDDEHELDDTGLLEGGVDMQELFTAAD
REYAPSGRAWAPPTHRIDDDPFAHVLVDEAQDLTPMQWRMVGRRGRAASWTIVGDPAQSSWPVPAESAAARAGALEGKEV
HEFHLSTNYRNSSEIYAHAAAYAERVGLDADLPTAVRSTGVEPTVLAGIADLESATREAVVQMAAAVEGTVGIVVPVARR
SEVNAWLASWPEVADDAPGSRAAVDSSVAPSGDDRIVVLTGLDTKGLEFDGIVVVRPQEIEDESATGRATLYVVLTRATQ
LLTTLS
>Mature_725_residues
SEELVEREIAAEQAFVDRVYVQLAESARQAQALAKEGHSRGRLGHEGGLVERDAMVFQAARRIAQLDAAHEGLVFGRLDM
TAEVDPEPRYVGRIGLRDANRDSLLIDWRAPAAAVFYQATAAEPHDVVRRRVLRCAGPQVVGVEDELLDAAAETSLPIVG
EGALMAQLSRARDRSMHSIVATIQAEQDRAIRAPGKGVVSISGGPGTGKTVVALHRAAYLLYNDRRRYEGGGVLIVGPSG
VFMRYIERVLPSLGETAVALRSLGEVVDGVRATRHDEPTVADVKGSARMAELMRRTARQQAPGSPREFRIFWRDDTIVLD
RGELGRLRRQLMSQGRRNRQLPRVAHALLDAMWRQVRGERGRDRGRESFDDEMLSNQSFVDFAAAWWPPLDALEVFGWLR
DPELLSRVGDGVVTPEEQRLLAKSWGEAVGLSVEDVPLLDELRYALGDVPARTDDEHELDDTGLLEGGVDMQELFTAADR
EYAPSGRAWAPPTHRIDDDPFAHVLVDEAQDLTPMQWRMVGRRGRAASWTIVGDPAQSSWPVPAESAAARAGALEGKEVH
EFHLSTNYRNSSEIYAHAAAYAERVGLDADLPTAVRSTGVEPTVLAGIADLESATREAVVQMAAAVEGTVGIVVPVARRS
EVNAWLASWPEVADDAPGSRAAVDSSVAPSGDDRIVVLTGLDTKGLEFDGIVVVRPQEIEDESATGRATLYVVLTRATQL
LTTLS

Specific function: Catalyzes the unwinding of duplex DNA in the 3' to 5' direction; this reaction is dependent on the hydrolysis of ATP [H]

COG id: COG3973

COG function: function code R; Superfamily I DNA and RNA helicases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000212
- InterPro:   IPR014016 [H]

Pfam domain/function: PF00580 UvrD-helicase [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 79204; Mature: 79073

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEELVEREIAAEQAFVDRVYVQLAESARQAQALAKEGHSRGRLGHEGGLVERDAMVFQA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
ARRIAQLDAAHEGLVFGRLDMTAEVDPEPRYVGRIGLRDANRDSLLIDWRAPAAAVFYQA
HHHHHHHHHHHCCEEEEEECCEEECCCCCCEEEEECCCCCCCCCEEEECCCCHHHHEEEC
TAAEPHDVVRRRVLRCAGPQVVGVEDELLDAAAETSLPIVGEGALMAQLSRARDRSMHSI
CCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHH
VATIQAEQDRAIRAPGKGVVSISGGPGTGKTVVALHRAAYLLYNDRRRYEGGGVLIVGPS
HHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHEEECCCEEECCCCEEEECCC
GVFMRYIERVLPSLGETAVALRSLGEVVDGVRATRHDEPTVADVKGSARMAELMRRTARQ
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHH
QAPGSPREFRIFWRDDTIVLDRGELGRLRRQLMSQGRRNRQLPRVAHALLDAMWRQVRGE
CCCCCCCEEEEEEECCEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
RGRDRGRESFDDEMLSNQSFVDFAAAWWPPLDALEVFGWLRDPELLSRVGDGVVTPEEQR
CCHHCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCCCCHHHH
LLAKSWGEAVGLSVEDVPLLDELRYALGDVPARTDDEHELDDTGLLEGGVDMQELFTAAD
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
REYAPSGRAWAPPTHRIDDDPFAHVLVDEAQDLTPMQWRMVGRRGRAASWTIVGDPAQSS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCC
WPVPAESAAARAGALEGKEVHEFHLSTNYRNSSEIYAHAAAYAERVGLDADLPTAVRSTG
CCCCCHHHHHHHCCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCC
VEPTVLAGIADLESATREAVVQMAAAVEGTVGIVVPVARRSEVNAWLASWPEVADDAPGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCHHHCCCCCC
RAAVDSSVAPSGDDRIVVLTGLDTKGLEFDGIVVVRPQEIEDESATGRATLYVVLTRATQ
CHHCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEHHHHHH
LLTTLS
HHHHCC
>Mature Secondary Structure 
SEELVEREIAAEQAFVDRVYVQLAESARQAQALAKEGHSRGRLGHEGGLVERDAMVFQA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
ARRIAQLDAAHEGLVFGRLDMTAEVDPEPRYVGRIGLRDANRDSLLIDWRAPAAAVFYQA
HHHHHHHHHHHCCEEEEEECCEEECCCCCCEEEEECCCCCCCCCEEEECCCCHHHHEEEC
TAAEPHDVVRRRVLRCAGPQVVGVEDELLDAAAETSLPIVGEGALMAQLSRARDRSMHSI
CCCCHHHHHHHHHHHHCCCCEECCHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHH
VATIQAEQDRAIRAPGKGVVSISGGPGTGKTVVALHRAAYLLYNDRRRYEGGGVLIVGPS
HHHHHHCCCCCEECCCCCEEEECCCCCCCHHHHHHHHHHHEEECCCEEECCCCEEEECCC
GVFMRYIERVLPSLGETAVALRSLGEVVDGVRATRHDEPTVADVKGSARMAELMRRTARQ
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHH
QAPGSPREFRIFWRDDTIVLDRGELGRLRRQLMSQGRRNRQLPRVAHALLDAMWRQVRGE
CCCCCCCEEEEEEECCEEEECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCC
RGRDRGRESFDDEMLSNQSFVDFAAAWWPPLDALEVFGWLRDPELLSRVGDGVVTPEEQR
CCHHCCCHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHCCCCCCCHHHH
LLAKSWGEAVGLSVEDVPLLDELRYALGDVPARTDDEHELDDTGLLEGGVDMQELFTAAD
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHC
REYAPSGRAWAPPTHRIDDDPFAHVLVDEAQDLTPMQWRMVGRRGRAASWTIVGDPAQSS
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCHHHHHHCCCCCCEEEEEECCCCCCC
WPVPAESAAARAGALEGKEVHEFHLSTNYRNSSEIYAHAAAYAERVGLDADLPTAVRSTG
CCCCCHHHHHHHCCCCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHCC
VEPTVLAGIADLESATREAVVQMAAAVEGTVGIVVPVARRSEVNAWLASWPEVADDAPGS
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHCCCHHHCCCCCC
RAAVDSSVAPSGDDRIVVLTGLDTKGLEFDGIVVVRPQEIEDESATGRATLYVVLTRATQ
CHHCCCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCCEEEEEEHHHHHH
LLTTLS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]