| Definition | Nocardioides sp. JS614 chromosome, complete genome. |
|---|---|
| Accession | NC_008699 |
| Length | 4,985,871 |
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The map label for this gene is dnaJ2 [H]
Identifier: 119718580
GI number: 119718580
Start: 4611654
End: 4612844
Strand: Reverse
Name: dnaJ2 [H]
Synonym: Noca_4361
Alternate gene names: 119718580
Gene position: 4612844-4611654 (Counterclockwise)
Preceding gene: 119718581
Following gene: 119718579
Centisome position: 92.52
GC content: 72.88
Gene sequence:
>1191_bases GTGAGCACCACTGACGGCTTCCGGGCCGACTGGGCCCAGAAGGACTTCTACGCCGAGCTGGGCGTGACGAAGAACGCCTC GGCCGAGGAGATCAAGAAGGCCTACCGCAAGCTGGCGCGCGCCAACCACCCCGACTCCAACCCCGGCGACTCTGCGGACA GCAAGGCCAAGCACGACAAGTTCAAGGCGGTCGCCGAGGCCTACGACGTCATCGGCGACCCCGAGAAGCGCAAGAAGTAC GACGAGATGCGCGAGCTCTACGGCTCGGGCGCGTTCCGTGGCGGCTTCGGGGGTGGCGGCCAGGGCGGAGGGTTCAACCT CGACGACCTGCTGCGCGACCGGGCGTCCGGTGGCGGAGGCGGCTTCGGTGACATGTTCGGCGACCTCTTCGGGGGCGGCT TCGGCCGGGGCCGGCAGCACCAGCGGCCGCGGGCGCAGAAGGGCCAGGACGTCGAGACCACGGCGACGATCAGCTTCACC GACGCCATCGACGGCGTCACGATCTCGCTGCGGCTCACCTCGGACGCGCCGTGCCCGGACTGCCACGGCACCGGCGGCAA GCCCGGCACCAAGCCGCACGTGTGCCCCGAATGCGACGGCGCCGGCTTCGTGGTGTCCTCCGCCGGCGGGGCGTTCTCGA TCAACGAGACCTGCCCCCGCTGCGGCGGCCGCCAGCTCGTGTACGACGAGGCCTGCCCGACCTGCCACGGCTCCGGTCGC GGCACCTCGGCGCGCTCCATCCAGGCGCGGATCCCGGCCGGGGTGCGCGACGGCCAGCGGATCCGCCTGCGCGGCAAGGG CGGCGCCGGCGAGAACGGCGGCCCGGCCGGCGACCTGTTCGTCACCGTCAAGGTCTCCCCGCACCGGCTGTTCGGCCGCA AGGGTGACAACCTCACCCTCGACGTGCCGGTCTCCTTCGACGAGCTCGCCCTCGGCGCGGATCTGAAGATCCCGACCCTC GGCGGCGCCCCGGTGACCCTCAAGGTCCCCGCCGGCACCCCCAACGGCCGGACCTTCCGGGTGCGCGGCCGGGGTGCTCC CAAGTCTGACGGCAGCCGGGGCGACCTGCTCGCCACTGTCGAGGTCCAGGTGCCGGCCGTGCTCGACACCGCCGCCCGGG AGGCGGTCCAGGCCTACCGCGACGCGAGCGCCGGCAAGCCGCTGCGCTCCAAGCTGTTCGAGGAGGCGTGA
Upstream 100 bases:
>100_bases CTGGTGGTCGACCCGCCGAGCGGGCCCACCGCCTAGCCGCAGAGCCACTGCGACGGGTTGATGCGAACGATCACGACGAG GACGGAGAGGGGGTGCGTGG
Downstream 100 bases:
>100_bases GATGCCGACCCGCCGACCCCCGTTCGAGCCGCCCGGCCCCGATGCCGCGGTGTTCGTCATCAGCGTCGCCGCCGAGCTGA GCGGCCTGCACCCGCAGACG
Product: chaperone protein DnaJ
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 396; Mature: 395
Protein sequence:
>396_residues MSTTDGFRADWAQKDFYAELGVTKNASAEEIKKAYRKLARANHPDSNPGDSADSKAKHDKFKAVAEAYDVIGDPEKRKKY DEMRELYGSGAFRGGFGGGGQGGGFNLDDLLRDRASGGGGGFGDMFGDLFGGGFGRGRQHQRPRAQKGQDVETTATISFT DAIDGVTISLRLTSDAPCPDCHGTGGKPGTKPHVCPECDGAGFVVSSAGGAFSINETCPRCGGRQLVYDEACPTCHGSGR GTSARSIQARIPAGVRDGQRIRLRGKGGAGENGGPAGDLFVTVKVSPHRLFGRKGDNLTLDVPVSFDELALGADLKIPTL GGAPVTLKVPAGTPNGRTFRVRGRGAPKSDGSRGDLLATVEVQVPAVLDTAAREAVQAYRDASAGKPLRSKLFEEA
Sequences:
>Translated_396_residues MSTTDGFRADWAQKDFYAELGVTKNASAEEIKKAYRKLARANHPDSNPGDSADSKAKHDKFKAVAEAYDVIGDPEKRKKY DEMRELYGSGAFRGGFGGGGQGGGFNLDDLLRDRASGGGGGFGDMFGDLFGGGFGRGRQHQRPRAQKGQDVETTATISFT DAIDGVTISLRLTSDAPCPDCHGTGGKPGTKPHVCPECDGAGFVVSSAGGAFSINETCPRCGGRQLVYDEACPTCHGSGR GTSARSIQARIPAGVRDGQRIRLRGKGGAGENGGPAGDLFVTVKVSPHRLFGRKGDNLTLDVPVSFDELALGADLKIPTL GGAPVTLKVPAGTPNGRTFRVRGRGAPKSDGSRGDLLATVEVQVPAVLDTAAREAVQAYRDASAGKPLRSKLFEEA >Mature_395_residues STTDGFRADWAQKDFYAELGVTKNASAEEIKKAYRKLARANHPDSNPGDSADSKAKHDKFKAVAEAYDVIGDPEKRKKYD EMRELYGSGAFRGGFGGGGQGGGFNLDDLLRDRASGGGGGFGDMFGDLFGGGFGRGRQHQRPRAQKGQDVETTATISFTD AIDGVTISLRLTSDAPCPDCHGTGGKPGTKPHVCPECDGAGFVVSSAGGAFSINETCPRCGGRQLVYDEACPTCHGSGRG TSARSIQARIPAGVRDGQRIRLRGKGGAGENGGPAGDLFVTVKVSPHRLFGRKGDNLTLDVPVSFDELALGADLKIPTLG GAPVTLKVPAGTPNGRTFRVRGRGAPKSDGSRGDLLATVEVQVPAVLDTAAREAVQAYRDASAGKPLRSKLFEEA
Specific function: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion. Unfolded proteins bind initially to dnaJ; upon
COG id: COG0484
COG function: function code O; DnaJ-class molecular chaperone with C-terminal Zn finger domain
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 J domain [H]
Homologues:
Organism=Homo sapiens, GI205360838, Length=379, Percent_Identity=31.3984168865435, Blast_Score=166, Evalue=4e-41, Organism=Homo sapiens, GI205360840, Length=381, Percent_Identity=31.2335958005249, Blast_Score=166, Evalue=5e-41, Organism=Homo sapiens, GI194328760, Length=360, Percent_Identity=30, Blast_Score=142, Evalue=5e-34, Organism=Homo sapiens, GI194328758, Length=360, Percent_Identity=30, Blast_Score=142, Evalue=7e-34, Organism=Homo sapiens, GI4504511, Length=360, Percent_Identity=29.4444444444444, Blast_Score=134, Evalue=1e-31, Organism=Homo sapiens, GI5031741, Length=370, Percent_Identity=30.5405405405405, Blast_Score=127, Evalue=2e-29, Organism=Homo sapiens, GI7706495, Length=377, Percent_Identity=28.6472148541114, Blast_Score=112, Evalue=5e-25, Organism=Homo sapiens, GI6631085, Length=384, Percent_Identity=27.34375, Blast_Score=106, Evalue=3e-23, Organism=Homo sapiens, GI194328762, Length=316, Percent_Identity=26.8987341772152, Blast_Score=105, Evalue=8e-23, Organism=Homo sapiens, GI9558755, Length=209, Percent_Identity=30.1435406698565, Blast_Score=81, Evalue=1e-15, Organism=Homo sapiens, GI68077168, Length=108, Percent_Identity=42.5925925925926, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI68077166, Length=108, Percent_Identity=42.5925925925926, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI194306642, Length=127, Percent_Identity=40.1574803149606, Blast_Score=76, Evalue=5e-14, Organism=Homo sapiens, GI194306640, Length=127, Percent_Identity=40.1574803149606, Blast_Score=76, Evalue=5e-14, Organism=Homo sapiens, GI88501736, Length=137, Percent_Identity=39.4160583941606, Blast_Score=74, Evalue=3e-13, Organism=Homo sapiens, GI27151736, Length=137, Percent_Identity=40.8759124087591, Blast_Score=73, Evalue=5e-13, Organism=Homo sapiens, GI4885495, Length=69, Percent_Identity=52.1739130434783, Blast_Score=72, Evalue=9e-13, Organism=Homo sapiens, GI17388799, Length=69, Percent_Identity=52.1739130434783, Blast_Score=72, Evalue=1e-12, Organism=Homo sapiens, GI201862587, Length=72, Percent_Identity=50, Blast_Score=72, Evalue=1e-12, Organism=Homo sapiens, GI201862518, Length=72, Percent_Identity=50, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI56549115, Length=72, Percent_Identity=50, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI5453690, Length=208, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI72534740, Length=137, Percent_Identity=37.956204379562, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI39204547, Length=176, Percent_Identity=33.5227272727273, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI47777312, Length=119, Percent_Identity=41.1764705882353, Blast_Score=69, Evalue=7e-12, Organism=Homo sapiens, GI23503241, Length=67, Percent_Identity=50.7462686567164, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI21553335, Length=81, Percent_Identity=45.679012345679, Blast_Score=67, Evalue=2e-11, Organism=Escherichia coli, GI1786197, Length=377, Percent_Identity=43.5013262599469, Blast_Score=279, Evalue=2e-76, Organism=Escherichia coli, GI1787235, Length=372, Percent_Identity=30.9139784946237, Blast_Score=156, Evalue=2e-39, Organism=Caenorhabditis elegans, GI17553096, Length=369, Percent_Identity=31.7073170731707, Blast_Score=162, Evalue=3e-40, Organism=Caenorhabditis elegans, GI17553098, Length=369, Percent_Identity=31.7073170731707, Blast_Score=162, Evalue=4e-40, Organism=Caenorhabditis elegans, GI17507263, Length=389, Percent_Identity=28.2776349614396, Blast_Score=110, Evalue=9e-25, Organism=Caenorhabditis elegans, GI17563890, Length=229, Percent_Identity=27.0742358078603, Blast_Score=80, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17554644, Length=130, Percent_Identity=38.4615384615385, Blast_Score=75, Evalue=6e-14, Organism=Caenorhabditis elegans, GI212645553, Length=68, Percent_Identity=51.4705882352941, Blast_Score=72, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17534355, Length=72, Percent_Identity=50, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17538236, Length=140, Percent_Identity=35.7142857142857, Blast_Score=65, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6321094, Length=422, Percent_Identity=29.3838862559242, Blast_Score=133, Evalue=6e-32, Organism=Saccharomyces cerevisiae, GI6323870, Length=374, Percent_Identity=32.8877005347594, Blast_Score=132, Evalue=6e-32, Organism=Saccharomyces cerevisiae, GI6324265, Length=359, Percent_Identity=29.5264623955432, Blast_Score=132, Evalue=9e-32, Organism=Saccharomyces cerevisiae, GI6323119, Length=381, Percent_Identity=27.0341207349081, Blast_Score=105, Evalue=1e-23, Organism=Saccharomyces cerevisiae, GI6323813, Length=132, Percent_Identity=37.8787878787879, Blast_Score=66, Evalue=1e-11, Organism=Saccharomyces cerevisiae, GI6322194, Length=67, Percent_Identity=47.7611940298507, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI45549272, Length=400, Percent_Identity=30.25, Blast_Score=155, Evalue=5e-38, Organism=Drosophila melanogaster, GI45552813, Length=400, Percent_Identity=30.25, Blast_Score=155, Evalue=6e-38, Organism=Drosophila melanogaster, GI45552811, Length=400, Percent_Identity=30.25, Blast_Score=154, Evalue=7e-38, Organism=Drosophila melanogaster, GI24646562, Length=368, Percent_Identity=28.804347826087, Blast_Score=119, Evalue=4e-27, Organism=Drosophila melanogaster, GI24646560, Length=368, Percent_Identity=28.804347826087, Blast_Score=119, Evalue=4e-27, Organism=Drosophila melanogaster, GI24646558, Length=368, Percent_Identity=28.804347826087, Blast_Score=119, Evalue=4e-27, Organism=Drosophila melanogaster, GI24646556, Length=368, Percent_Identity=28.804347826087, Blast_Score=119, Evalue=4e-27, Organism=Drosophila melanogaster, GI21357547, Length=368, Percent_Identity=28.804347826087, Blast_Score=119, Evalue=4e-27, Organism=Drosophila melanogaster, GI19920464, Length=378, Percent_Identity=28.5714285714286, Blast_Score=112, Evalue=4e-25, Organism=Drosophila melanogaster, GI20129487, Length=359, Percent_Identity=28.9693593314763, Blast_Score=110, Evalue=2e-24, Organism=Drosophila melanogaster, GI24584014, Length=359, Percent_Identity=28.9693593314763, Blast_Score=110, Evalue=2e-24, Organism=Drosophila melanogaster, GI28574949, Length=377, Percent_Identity=24.9336870026525, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI85726398, Length=389, Percent_Identity=25.4498714652956, Blast_Score=99, Evalue=5e-21, Organism=Drosophila melanogaster, GI18858081, Length=364, Percent_Identity=26.9230769230769, Blast_Score=86, Evalue=5e-17, Organism=Drosophila melanogaster, GI17648033, Length=108, Percent_Identity=38.8888888888889, Blast_Score=72, Evalue=8e-13, Organism=Drosophila melanogaster, GI24584630, Length=108, Percent_Identity=38.8888888888889, Blast_Score=72, Evalue=9e-13, Organism=Drosophila melanogaster, GI24654066, Length=88, Percent_Identity=44.3181818181818, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24654070, Length=88, Percent_Identity=44.3181818181818, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24654068, Length=88, Percent_Identity=44.3181818181818, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24654072, Length=88, Percent_Identity=44.3181818181818, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24658562, Length=72, Percent_Identity=48.6111111111111, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI24658555, Length=72, Percent_Identity=48.6111111111111, Blast_Score=67, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012724 - InterPro: IPR002939 - InterPro: IPR001623 - InterPro: IPR018253 - InterPro: IPR008971 - InterPro: IPR015609 - InterPro: IPR003095 - InterPro: IPR001305 [H]
Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; PF00684 DnaJ_CXXCXGXG [H]
EC number: NA
Molecular weight: Translated: 41418; Mature: 41286
Theoretical pI: Translated: 8.72; Mature: 8.72
Prosite motif: PS00018 EF_HAND_1 ; PS50076 DNAJ_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 0.8 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 0.5 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSTTDGFRADWAQKDFYAELGVTKNASAEEIKKAYRKLARANHPDSNPGDSADSKAKHDK CCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH FKAVAEAYDVIGDPEKRKKYDEMRELYGSGAFRGGFGGGGQGGGFNLDDLLRDRASGGGG HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC GFGDMFGDLFGGGFGRGRQHQRPRAQKGQDVETTATISFTDAIDGVTISLRLTSDAPCPD CHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCC CHGTGGKPGTKPHVCPECDGAGFVVSSAGGAFSINETCPRCGGRQLVYDEACPTCHGSGR CCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCEEEECCCCCCCCCCCC GTSARSIQARIPAGVRDGQRIRLRGKGGAGENGGPAGDLFVTVKVSPHRLFGRKGDNLTL CCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECHHHHHCCCCCCEEE DVPVSFDELALGADLKIPTLGGAPVTLKVPAGTPNGRTFRVRGRGAPKSDGSRGDLLATV EECCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCCEEEEE EVQVPAVLDTAAREAVQAYRDASAGKPLRSKLFEEA EEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC >Mature Secondary Structure STTDGFRADWAQKDFYAELGVTKNASAEEIKKAYRKLARANHPDSNPGDSADSKAKHDK CCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHH FKAVAEAYDVIGDPEKRKKYDEMRELYGSGAFRGGFGGGGQGGGFNLDDLLRDRASGGGG HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCC GFGDMFGDLFGGGFGRGRQHQRPRAQKGQDVETTATISFTDAIDGVTISLRLTSDAPCPD CHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCC CHGTGGKPGTKPHVCPECDGAGFVVSSAGGAFSINETCPRCGGRQLVYDEACPTCHGSGR CCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCEEEECCCCCCCCCCCC GTSARSIQARIPAGVRDGQRIRLRGKGGAGENGGPAGDLFVTVKVSPHRLFGRKGDNLTL CCCCCEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCEEEEEEEECHHHHHCCCCCCEEE DVPVSFDELALGADLKIPTLGGAPVTLKVPAGTPNGRTFRVRGRGAPKSDGSRGDLLATV EECCCHHHHCCCCCCCCCCCCCCCEEEEECCCCCCCCEEEEECCCCCCCCCCCCCEEEEE EVQVPAVLDTAAREAVQAYRDASAGKPLRSKLFEEA EEECCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA