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The map label for this gene is trmH [C]

Identifier: 119718571

GI number: 119718571

Start: 4601675

End: 4602334

Strand: Reverse

Name: trmH [C]

Synonym: Noca_4352

Alternate gene names: 119718571

Gene position: 4602334-4601675 (Counterclockwise)

Preceding gene: 119718573

Following gene: 119718569

Centisome position: 92.31

GC content: 73.94

Gene sequence:

>660_bases
ATGCCCCACGGGCCACCCGAGGTCGGCGTCGGCCCCTGGCGGGGGGAGTGGCCGACCGGGGCGCAGTACGACGCCGCGCT
GCTCGCGGCCGGCGACCGGCGCAACGTGGTCGACCGCTACCGGTACTGGTCGGTCGAGGCGATCGTCGCCGACCTGGACA
CCCGGCGGCACGACTTCCACGTGGCCATCGAGAACTGGCAGCACGACTTCAACATCGGGACGATCGTGCGCACCGCGAAC
GCCTTCTTGGCGGCGGAGGTGCACATCGTGGGGAACCGGCGGTGGAACCGCCGCGGCGCGATGGTGACCGACCGGTACCA
GCACGTCCGGCACCACCCGACGGTCGAGGCGCTGGCCGGCTACCTGCACGAACACCCCGGCGGCCCGGTCGCGCTGCACG
GCATCGACAACCTGCCGGGCTCGGCCCACCTGGAGACGACCGAGGTGCCGCGCCGGGTGTGCTTCCTGTTCGGGCAGGAG
GGGCCGGGCCTCTCCGAGACCGCCCGGGAGGCCTGCGACGGCACGTTCTCGATCGCGCAGTTCGGCTCGACCCGCTCCAT
CAACGCCTCCGCGGCCGCCGCGATCGCCATGCACGCGTGGGTGCGGGCGTACGCCGACCTGTCCGGGGGCCGGTCGGACG
GCGGGGTCTGGCGCGGCTGA

Upstream 100 bases:

>100_bases
ACGCAGCAACGGTACCTGGCGGGTCCTGAGCCCCGGCGCCGAACGCGAAGTGTTCGCCGTACCGTTACCCGCTGTGGAGG
AGCGCGCGCCGTACGACCCG

Downstream 100 bases:

>100_bases
GGCCAGGCCGACGCGGAGGTCAGCGCGGCAGCAGTCGCCCGAGCGCCTCGACGGCGGCCTCGGGTCCGTCGACGATGGTC
CCGGCGTCGTGGGGCAGCTC

Product: tRNA/rRNA methyltransferase SpoU

Products: S-adenosyl-L-homocysteine; tRNATyr Containing 2'-O-methylguanosine [C]

Alternate protein names: RNA Methyltransferase; rRNA Methylase; TRNA/RRNA MethyltransferaU; RNA Methyltransferase TrmH Family; 23S RRNA Methyltransferase; TrmH Family RNA Methyltransferase; RNA Methylase Family Protein; Spou RRNA Methylase Family Protein; Methyltransferase; SpoU RRNA Methylase Family Protein; SPOU RRNA Methylase Family Protein

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MPHGPPEVGVGPWRGEWPTGAQYDAALLAAGDRRNVVDRYRYWSVEAIVADLDTRRHDFHVAIENWQHDFNIGTIVRTAN
AFLAAEVHIVGNRRWNRRGAMVTDRYQHVRHHPTVEALAGYLHEHPGGPVALHGIDNLPGSAHLETTEVPRRVCFLFGQE
GPGLSETAREACDGTFSIAQFGSTRSINASAAAAIAMHAWVRAYADLSGGRSDGGVWRG

Sequences:

>Translated_219_residues
MPHGPPEVGVGPWRGEWPTGAQYDAALLAAGDRRNVVDRYRYWSVEAIVADLDTRRHDFHVAIENWQHDFNIGTIVRTAN
AFLAAEVHIVGNRRWNRRGAMVTDRYQHVRHHPTVEALAGYLHEHPGGPVALHGIDNLPGSAHLETTEVPRRVCFLFGQE
GPGLSETAREACDGTFSIAQFGSTRSINASAAAAIAMHAWVRAYADLSGGRSDGGVWRG
>Mature_218_residues
PHGPPEVGVGPWRGEWPTGAQYDAALLAAGDRRNVVDRYRYWSVEAIVADLDTRRHDFHVAIENWQHDFNIGTIVRTANA
FLAAEVHIVGNRRWNRRGAMVTDRYQHVRHHPTVEALAGYLHEHPGGPVALHGIDNLPGSAHLETTEVPRRVCFLFGQEG
PGLSETAREACDGTFSIAQFGSTRSINASAAAAIAMHAWVRAYADLSGGRSDGGVWRG

Specific function: Specifically Methylates Guanosine-18 In Various tRNAs. [C]

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.34 [C]

Molecular weight: Translated: 24033; Mature: 23902

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00191 CYTOCHROME_B5_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHGPPEVGVGPWRGEWPTGAQYDAALLAAGDRRNVVDRYRYWSVEAIVADLDTRRHDFH
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEHHCCCCCEEE
VAIENWQHDFNIGTIVRTANAFLAAEVHIVGNRRWNRRGAMVTDRYQHVRHHPTVEALAG
EEEECCCCCCCHHHHHHHHCEEEEEEEEEECCCCCCCCCCEEHHHHHHHHCCCCHHHHHH
YLHEHPGGPVALHGIDNLPGSAHLETTEVPRRVCFLFGQEGPGLSETAREACDGTFSIAQ
HHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHEEEEECCCCCCCCHHHHHHCCCCEEHHH
FGSTRSINASAAAAIAMHAWVRAYADLSGGRSDGGVWRG
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
PHGPPEVGVGPWRGEWPTGAQYDAALLAAGDRRNVVDRYRYWSVEAIVADLDTRRHDFH
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHEEHHCCCCCEEE
VAIENWQHDFNIGTIVRTANAFLAAEVHIVGNRRWNRRGAMVTDRYQHVRHHPTVEALAG
EEEECCCCCCCHHHHHHHHCEEEEEEEEEECCCCCCCCCCEEHHHHHHHHCCCCHHHHHH
YLHEHPGGPVALHGIDNLPGSAHLETTEVPRRVCFLFGQEGPGLSETAREACDGTFSIAQ
HHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHEEEEECCCCCCCCHHHHHHCCCCEEHHH
FGSTRSINASAAAAIAMHAWVRAYADLSGGRSDGGVWRG
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-methionine; tRNATyr [C]

Specific reaction: S-Adenosyl-L-methionine + tRNATyr = S-adenosyl-L-homocysteine + tRNATyr Containing 2'-O-methylguanosine [C]

General reaction: Methyl group transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA