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The map label for this gene is hcrA [H]

Identifier: 119718490

GI number: 119718490

Start: 4510583

End: 4513066

Strand: Reverse

Name: hcrA [H]

Synonym: Noca_4271

Alternate gene names: 119718490

Gene position: 4513066-4510583 (Counterclockwise)

Preceding gene: 119718491

Following gene: 119718489

Centisome position: 90.52

GC content: 71.66

Gene sequence:

>2484_bases
ATGTCTGACCAGCTGCGCACCGTCGGCACCGATGTCCCCCGCGTGGAGACGGTCGAGAAGCTGACCGGCGACGCGCTCTA
CACCGGCGACCTGCTGCTGCCGGGCATGCTGCACGCGAAGGTCAAGCACAGCCCGCACGCCCGCGCCCGGATCCTGCGCG
TCGACACCGCACGAGCCGAGGCGCTCCCGGGCGTCCACGCCGTCCTCACCGGCCACGAGCTCGACTACAAGATCGGGCTG
TACGTCGTCGACAAGGACATCCTCGCCAAGGACGTGGTCCGCCACTTCGGCGAGGCGGTCGCCGCGGTCGCCGCGGAGAC
CCCGGAGATCGCGAGCGCGGCGGTCGACCTGATCGAGGTCGAGTACGACGTGCTCACCCCGGTGCTCGACCCGATGGAGG
CGATCCGGGACGGGGCGCCGCTGGTGCACCCCGACCTCGGCAGCTATGCGTACGTCGAGGCCGCGTTCAGCCCGCAGCCC
GGCACGAACGTCGCCCACGTCCAGAAGGTCCGCAAGGGCGACCTCGACCGGGGCTTCGCCGAGGCGGAGTGGGTCGTCGA
GCGCGAGTACACCAACCCCTCCGTCCAGCACGTGCCGCTGGAGACCCACGTCGCGGTCGTGCAGTGGAAGGCCGGCGACC
AGGTCACGATCTGGACCAGCGCCCAGTCGCCGTTCACCGTGCGCAACCTGTTCTGCACCGCGATGCGGCTGCCGCTCAAC
CAGGTCCGGGTGGTCGTCCCGCACGTCGGCGGCGGCTTCGGCGGCAAGGCCGGCATCCACCTCGAGCCGCTGGTGGCCTG
CCTGTCCCGCAAGGCCGGCGGCCGCCCGGTGCGGCTGCAGGCGACCCGCGAGGAGGAGTTCAGCCTGCTCCCGTGCCGCA
GCGCGCTCACCTACCGGATCCGGACCGGCGTCCGCTCCGACGGCACCATCACCGCCCAGCAGATGACGATGTACTGGGAT
GCGGGCGCGTACGCCGACTACGCCGTCAACGTGACCCGCGCGTCGGGCTACTCCGCGGGCGGCCCCTACGAGATCCCGAA
CGCGGCGGTCGACTCCTACGCGATCTACACGAACAAGCCGTACGGCACGGCGTACCGGGGCTTCGGGCACGTGGAGTTCT
TCTGGGGCCTCGAGCGGCACATGGAGCTGGTCGCCCAGGCGATCGGCATGGACCCCCTGGAGTTCCGGCGCCGGAACCTG
CTCCGGCCGGGCTCGCTGACGATGACCGGCGAGCGGATCACCGAGCACACCGGTGACCCGCGGGCCTGCCTCGACGCGGT
CGCCGAGGCGATCGACTACGGCCGGCTCACGCCGGAGGAGGCCGCGCACGAGCGCAGCACCGGTCGCCGGATCGGCAAGG
GCGTCGCCACGCTGCACAAGGCACCGGCGATGCCGTCGTTCACCGCGACGGCCGCAGTGGTGAAGATGAACTCCGACGCC
AGCGTGGTGGTCAACATCGCGTTGATGGAGATCGGGCAGGGCTGCAACACCGCCCTCGCGCAGATCGTCGCGGAGCGGCT
CCGGTTCCCGGTCGAGCGGGTCAAGGTCGCGGTCGAGCGGGACACCGACAAGGACCCCTACGACTGGCAGACGGTGGCCT
CCAAGGGCCTGATCCTCTCCGGCAACGCCTGCCTGCTGGCCTGCGACGACCTGCTCCGGCAGGCCTACGAGGTCGCCGGC
CAGGTGCTGCGCGCCAACGTCGCCGACCTCGACCACGACGCCGACCGGGTCTTCGTCAAGCACCGGCCCGAGGAGTCGGT
CACCTTCGCCGAGCTCTCGGTCGGCTACGCCTTCCCGAACGGCAACGGCATCGGCGGGCCGCTGGTCGGGGTCGGGCGCT
ACATCGCCCAGGGCCTGACCAACCTCGACAAGGAGACCGGGCAGGGCCTGCCGGCGCTCGACTGGACGTACGGCGCGCAC
GGCGTGGTCGTCGACGTCGACCCCGAGACCGGCGAGTTCGACGTGCTGGCCATCTCCTCGGCGTACGACGTGGGCCGGGT
CGTCAACCCGGGGCTGGTCCGCGGGCAGGCGATCGGCGGGATGGTGCAGGGCCTGGGCACGGCGCTGTGTGAGGGCTACA
TCTACGACCAGCAGGGCCGCCTGCTGAACCCGTCGTTCACCGACAACAAGATCCCGACCGCCCGGGACATCCCGGCCCGC
ATCGACAGCGCGGTCGTCGAGACCGCCCAGCTCGACGGCCCGTTCGGCGCCCGCGGGGTGGGGGAGCACCCGATGATCTC
GGTCGCCCCCGCCATCGGCAACGCCATCCAGCACGCCACCGGCGCCGAGCTGCTGCACATGCCGATGCGCTTCGAGGACG
TGTGGCGGGCGCTGCAGCGCCACGAGCCCATCGACAACTGGATCACCGAGACGCCGGTCGGCTCCTGCCGCTCGGACCTG
CCCGGCACGAACGGGACGGCGCACCCCGCCGTACCCGTCGCGGACACCGGCCCCACCCACACCCCGGAGGTAGCACTGCC
ATGA

Upstream 100 bases:

>100_bases
TGCCGCTGCACCGGCTACGAGCAGATCGTCGAGGCGGTCCTGGACGCCTCCGGTCAGCTCGACGACCCGACCAACCAGCC
CGTGACGGGGGGACTGCGCC

Downstream 100 bases:

>100_bases
CCCGTCCGATCGAGGTACGCAAGGTCCCGATCGAGCACGTCAGCGACGCGGCCGGCCTGGCCGACCTGATCGACGCCGGC
GTGTTCTCGGCCGACGACGT

Product: xanthine dehydrogenase, molybdenum binding subunit apoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 827; Mature: 826

Protein sequence:

>827_residues
MSDQLRTVGTDVPRVETVEKLTGDALYTGDLLLPGMLHAKVKHSPHARARILRVDTARAEALPGVHAVLTGHELDYKIGL
YVVDKDILAKDVVRHFGEAVAAVAAETPEIASAAVDLIEVEYDVLTPVLDPMEAIRDGAPLVHPDLGSYAYVEAAFSPQP
GTNVAHVQKVRKGDLDRGFAEAEWVVEREYTNPSVQHVPLETHVAVVQWKAGDQVTIWTSAQSPFTVRNLFCTAMRLPLN
QVRVVVPHVGGGFGGKAGIHLEPLVACLSRKAGGRPVRLQATREEEFSLLPCRSALTYRIRTGVRSDGTITAQQMTMYWD
AGAYADYAVNVTRASGYSAGGPYEIPNAAVDSYAIYTNKPYGTAYRGFGHVEFFWGLERHMELVAQAIGMDPLEFRRRNL
LRPGSLTMTGERITEHTGDPRACLDAVAEAIDYGRLTPEEAAHERSTGRRIGKGVATLHKAPAMPSFTATAAVVKMNSDA
SVVVNIALMEIGQGCNTALAQIVAERLRFPVERVKVAVERDTDKDPYDWQTVASKGLILSGNACLLACDDLLRQAYEVAG
QVLRANVADLDHDADRVFVKHRPEESVTFAELSVGYAFPNGNGIGGPLVGVGRYIAQGLTNLDKETGQGLPALDWTYGAH
GVVVDVDPETGEFDVLAISSAYDVGRVVNPGLVRGQAIGGMVQGLGTALCEGYIYDQQGRLLNPSFTDNKIPTARDIPAR
IDSAVVETAQLDGPFGARGVGEHPMISVAPAIGNAIQHATGAELLHMPMRFEDVWRALQRHEPIDNWITETPVGSCRSDL
PGTNGTAHPAVPVADTGPTHTPEVALP

Sequences:

>Translated_827_residues
MSDQLRTVGTDVPRVETVEKLTGDALYTGDLLLPGMLHAKVKHSPHARARILRVDTARAEALPGVHAVLTGHELDYKIGL
YVVDKDILAKDVVRHFGEAVAAVAAETPEIASAAVDLIEVEYDVLTPVLDPMEAIRDGAPLVHPDLGSYAYVEAAFSPQP
GTNVAHVQKVRKGDLDRGFAEAEWVVEREYTNPSVQHVPLETHVAVVQWKAGDQVTIWTSAQSPFTVRNLFCTAMRLPLN
QVRVVVPHVGGGFGGKAGIHLEPLVACLSRKAGGRPVRLQATREEEFSLLPCRSALTYRIRTGVRSDGTITAQQMTMYWD
AGAYADYAVNVTRASGYSAGGPYEIPNAAVDSYAIYTNKPYGTAYRGFGHVEFFWGLERHMELVAQAIGMDPLEFRRRNL
LRPGSLTMTGERITEHTGDPRACLDAVAEAIDYGRLTPEEAAHERSTGRRIGKGVATLHKAPAMPSFTATAAVVKMNSDA
SVVVNIALMEIGQGCNTALAQIVAERLRFPVERVKVAVERDTDKDPYDWQTVASKGLILSGNACLLACDDLLRQAYEVAG
QVLRANVADLDHDADRVFVKHRPEESVTFAELSVGYAFPNGNGIGGPLVGVGRYIAQGLTNLDKETGQGLPALDWTYGAH
GVVVDVDPETGEFDVLAISSAYDVGRVVNPGLVRGQAIGGMVQGLGTALCEGYIYDQQGRLLNPSFTDNKIPTARDIPAR
IDSAVVETAQLDGPFGARGVGEHPMISVAPAIGNAIQHATGAELLHMPMRFEDVWRALQRHEPIDNWITETPVGSCRSDL
PGTNGTAHPAVPVADTGPTHTPEVALP
>Mature_826_residues
SDQLRTVGTDVPRVETVEKLTGDALYTGDLLLPGMLHAKVKHSPHARARILRVDTARAEALPGVHAVLTGHELDYKIGLY
VVDKDILAKDVVRHFGEAVAAVAAETPEIASAAVDLIEVEYDVLTPVLDPMEAIRDGAPLVHPDLGSYAYVEAAFSPQPG
TNVAHVQKVRKGDLDRGFAEAEWVVEREYTNPSVQHVPLETHVAVVQWKAGDQVTIWTSAQSPFTVRNLFCTAMRLPLNQ
VRVVVPHVGGGFGGKAGIHLEPLVACLSRKAGGRPVRLQATREEEFSLLPCRSALTYRIRTGVRSDGTITAQQMTMYWDA
GAYADYAVNVTRASGYSAGGPYEIPNAAVDSYAIYTNKPYGTAYRGFGHVEFFWGLERHMELVAQAIGMDPLEFRRRNLL
RPGSLTMTGERITEHTGDPRACLDAVAEAIDYGRLTPEEAAHERSTGRRIGKGVATLHKAPAMPSFTATAAVVKMNSDAS
VVVNIALMEIGQGCNTALAQIVAERLRFPVERVKVAVERDTDKDPYDWQTVASKGLILSGNACLLACDDLLRQAYEVAGQ
VLRANVADLDHDADRVFVKHRPEESVTFAELSVGYAFPNGNGIGGPLVGVGRYIAQGLTNLDKETGQGLPALDWTYGAHG
VVVDVDPETGEFDVLAISSAYDVGRVVNPGLVRGQAIGGMVQGLGTALCEGYIYDQQGRLLNPSFTDNKIPTARDIPARI
DSAVVETAQLDGPFGARGVGEHPMISVAPAIGNAIQHATGAELLHMPMRFEDVWRALQRHEPIDNWITETPVGSCRSDLP
GTNGTAHPAVPVADTGPTHTPEVALP

Specific function: Catalyzes reductive dehydroxylation of 4-hydroxybenzoyl- CoA. Reaction is not reversible [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To xanthine oxidases [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=768, Percent_Identity=26.0416666666667, Blast_Score=215, Evalue=1e-55,
Organism=Homo sapiens, GI71773480, Length=779, Percent_Identity=25.4172015404365, Blast_Score=196, Evalue=9e-50,
Organism=Escherichia coli, GI1789246, Length=818, Percent_Identity=29.8288508557457, Blast_Score=304, Evalue=2e-83,
Organism=Escherichia coli, GI1789230, Length=775, Percent_Identity=30.4516129032258, Blast_Score=298, Evalue=7e-82,
Organism=Escherichia coli, GI1786478, Length=799, Percent_Identity=26.7834793491865, Blast_Score=165, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17540638, Length=763, Percent_Identity=24.5085190039318, Blast_Score=172, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI32566215, Length=591, Percent_Identity=23.1810490693739, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17539860, Length=781, Percent_Identity=22.663252240717, Blast_Score=139, Evalue=7e-33,
Organism=Drosophila melanogaster, GI17737937, Length=762, Percent_Identity=27.8215223097113, Blast_Score=223, Evalue=4e-58,
Organism=Drosophila melanogaster, GI24647193, Length=775, Percent_Identity=24.5161290322581, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24647199, Length=784, Percent_Identity=23.9795918367347, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24647201, Length=532, Percent_Identity=23.6842105263158, Blast_Score=86, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017607
- InterPro:   IPR000674
- InterPro:   IPR008274 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.3.99.20 [H]

Molecular weight: Translated: 89121; Mature: 88990

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDQLRTVGTDVPRVETVEKLTGDALYTGDLLLPGMLHAKVKHSPHARARILRVDTARAE
CCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCHHHHHHCCCCCCCEEEEEEECHHHH
ALPGVHAVLTGHELDYKIGLYVVDKDILAKDVVRHFGEAVAAVAAETPEIASAAVDLIEV
HCCCEEEEEECCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EYDVLTPVLDPMEAIRDGAPLVHPDLGSYAYVEAAFSPQPGTNVAHVQKVRKGDLDRGFA
HHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCC
EAEWVVEREYTNPSVQHVPLETHVAVVQWKAGDQVTIWTSAQSPFTVRNLFCTAMRLPLN
CCEEEEEECCCCCCCEECCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
QVRVVVPHVGGGFGGKAGIHLEPLVACLSRKAGGRPVRLQATREEEFSLLPCRSALTYRI
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCHHHEEHH
RTGVRSDGTITAQQMTMYWDAGAYADYAVNVTRASGYSAGGPYEIPNAAVDSYAIYTNKP
HCCCCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCC
YGTAYRGFGHVEFFWGLERHMELVAQAIGMDPLEFRRRNLLRPGSLTMTGERITEHTGDP
CCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECHHHHHCCCCH
RACLDAVAEAIDYGRLTPEEAAHERSTGRRIGKGVATLHKAPAMPSFTATAAVVKMNSDA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
SVVVNIALMEIGQGCNTALAQIVAERLRFPVERVKVAVERDTDKDPYDWQTVASKGLILS
EEEEEEEEHHHCCCHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCHHHHHCCCEEEE
GNACLLACDDLLRQAYEVAGQVLRANVADLDHDADRVFVKHRPEESVTFAELSVGYAFPN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEEEEECCC
GNGIGGPLVGVGRYIAQGLTNLDKETGQGLPALDWTYGAHGVVVDVDPETGEFDVLAISS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCCCCEEEEEEEC
AYDVGRVVNPGLVRGQAIGGMVQGLGTALCEGYIYDQQGRLLNPSFTDNKIPTARDIPAR
CCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCEEECCCCCEECCCCCCCCCCCCCCCHHH
IDSAVVETAQLDGPFGARGVGEHPMISVAPAIGNAIQHATGAELLHMPMRFEDVWRALQR
HHHHHHHHHHCCCCCCCCCCCCCCCEEECHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
HEPIDNWITETPVGSCRSDLPGTNGTAHPAVPVADTGPTHTPEVALP
CCCHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SDQLRTVGTDVPRVETVEKLTGDALYTGDLLLPGMLHAKVKHSPHARARILRVDTARAE
CCCCCCCCCCCCCHHHHHHHCCCEEEECCCCCCCHHHHHHCCCCCCCEEEEEEECHHHH
ALPGVHAVLTGHELDYKIGLYVVDKDILAKDVVRHFGEAVAAVAAETPEIASAAVDLIEV
HCCCEEEEEECCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
EYDVLTPVLDPMEAIRDGAPLVHPDLGSYAYVEAAFSPQPGTNVAHVQKVRKGDLDRGFA
HHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEECCCCCCCCHHHHHHHHHCCCCCCCC
EAEWVVEREYTNPSVQHVPLETHVAVVQWKAGDQVTIWTSAQSPFTVRNLFCTAMRLPLN
CCEEEEEECCCCCCCEECCCEEEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
QVRVVVPHVGGGFGGKAGIHLEPLVACLSRKAGGRPVRLQATREEEFSLLPCRSALTYRI
CEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCEEECCCHHHEEHH
RTGVRSDGTITAQQMTMYWDAGAYADYAVNVTRASGYSAGGPYEIPNAAVDSYAIYTNKP
HCCCCCCCEEEEEEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEECCC
YGTAYRGFGHVEFFWGLERHMELVAQAIGMDPLEFRRRNLLRPGSLTMTGERITEHTGDP
CCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEECHHHHHCCCCH
RACLDAVAEAIDYGRLTPEEAAHERSTGRRIGKGVATLHKAPAMPSFTATAAVVKMNSDA
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
SVVVNIALMEIGQGCNTALAQIVAERLRFPVERVKVAVERDTDKDPYDWQTVASKGLILS
EEEEEEEEHHHCCCHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCHHHHHCCCEEEE
GNACLLACDDLLRQAYEVAGQVLRANVADLDHDADRVFVKHRPEESVTFAELSVGYAFPN
CCEEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEEEEEEECCC
GNGIGGPLVGVGRYIAQGLTNLDKETGQGLPALDWTYGAHGVVVDVDPETGEFDVLAISS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEEEECCCCCCEEEEEEEC
AYDVGRVVNPGLVRGQAIGGMVQGLGTALCEGYIYDQQGRLLNPSFTDNKIPTARDIPAR
CCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCEEECCCCCEECCCCCCCCCCCCCCCHHH
IDSAVVETAQLDGPFGARGVGEHPMISVAPAIGNAIQHATGAELLHMPMRFEDVWRALQR
HHHHHHHHHHCCCCCCCCCCCCCCCEEECHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHH
HEPIDNWITETPVGSCRSDLPGTNGTAHPAVPVADTGPTHTPEVALP
CCCHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9490068 [H]