BacMap

Definition	Nocardioides sp. JS614 chromosome, complete genome.
Accession	NC_008699
Length	4,985,871

Click here to switch to the map view.

The map label for this gene is livF [H]

Identifier: 119718321

GI number: 119718321

Start: 4333319

End: 4334068

Strand: Reverse

Name: livF [H]

Synonym: Noca_4102

Alternate gene names: 119718321

Gene position: 4334068-4333319 (Counterclockwise)

Preceding gene: 119718322

Following gene: 119718320

Centisome position: 86.93

GC content: 69.73

Gene sequence:

>750_bases
ATGACGACCGCGAGCTCGGACCCGGCCCTGCTGGAGGTGTCGAACCTCCGCGTCAGGTTCGGTCACGTCGACGCGGTCCG
CGACGTCAGCCTGGCGGTGGGGCGAAGCCGTGTGGTCACCCTGCTCGGTCCCAACGGGGCGGGCAAGACCACCACGCTCA
AGGCCATCTGCGGCCTCTTGAGGCCCGCGCGCGGTGAGATCAGGATCAACGGCCGCCGCACCAACGGTGTCGTGGCCTCG
CGCGTCACCAAGCTGGGGGTGGGCTTGGTGCCGGAGGGCCGCCGGATCTTCCCGGCGCACACCGTCAAGGAGAACCTCGA
GCTGGGGGGCTTCATCTGGCGGCGTCAGCGCCCGGTCTTCGACGAGACGCTCGCCTCGGTTCTCGAGCTGTTCCCTCGTC
TGGCCGACCGGCTCGACCAACTCGCGGGCAGCCTGTCCGGGGGCGAGGCACAGATGCTGGCCGTGGGTCGCGCGATGATG
ACGCGTCCCAGCCTGCTCATCCTCGACGAGCCGAGCCTGGGCCTGGCACCCAAGATCGTCGACGAGCTGTACGACTTCTT
GGGCACGATCCGAGACCAGCAACAGCTGTCGATCCTCCTGGTCGAGCAGGCGGCCGACCGTGCCCTCCGGTTCGCCGACG
ACGCCTATCTCCTGAGCCAGGGGCGGGTCGTCGCCAGCGGTCCCGCTGAGGCGCTGCGAGAGGACGACCAGGTGCGCAGC
GTGTACTTCGGGGGGCTGGCCACCTCGTGA

Upstream 100 bases:

>100_bases
TCACGGTTCTGAACTTCGGTGAGGTGATCGCCCACGGCACGCCGCAAGAGATCGTCGACTCTCCCGTCGTCCGGGAGGCC
TACCTGGGAGGCGCGACCGT

Downstream 100 bases:

>100_bases
CCGGCGCCGAGCGCAGCTTCCCACTTCGCGACACACCGCAACCCGATCAGCAGCCCCCGATGGAGGGAGACGTCTTGTCC
GGAAACACCCCACTGGCCGC

Product: ABC transporter-like protein

Products: ADP; phosphate; L-leucine [Cytoplasm]; ADP; L-valine [Cytoplasm]; L-iso-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein F [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTTASSDPALLEVSNLRVRFGHVDAVRDVSLAVGRSRVVTLLGPNGAGKTTTLKAICGLLRPARGEIRINGRRTNGVVAS
RVTKLGVGLVPEGRRIFPAHTVKENLELGGFIWRRQRPVFDETLASVLELFPRLADRLDQLAGSLSGGEAQMLAVGRAMM
TRPSLLILDEPSLGLAPKIVDELYDFLGTIRDQQQLSILLVEQAADRALRFADDAYLLSQGRVVASGPAEALREDDQVRS
VYFGGLATS

Sequences:

>Translated_249_residues
MTTASSDPALLEVSNLRVRFGHVDAVRDVSLAVGRSRVVTLLGPNGAGKTTTLKAICGLLRPARGEIRINGRRTNGVVAS
RVTKLGVGLVPEGRRIFPAHTVKENLELGGFIWRRQRPVFDETLASVLELFPRLADRLDQLAGSLSGGEAQMLAVGRAMM
TRPSLLILDEPSLGLAPKIVDELYDFLGTIRDQQQLSILLVEQAADRALRFADDAYLLSQGRVVASGPAEALREDDQVRS
VYFGGLATS
>Mature_248_residues
TTASSDPALLEVSNLRVRFGHVDAVRDVSLAVGRSRVVTLLGPNGAGKTTTLKAICGLLRPARGEIRINGRRTNGVVASR
VTKLGVGLVPEGRRIFPAHTVKENLELGGFIWRRQRPVFDETLASVLELFPRLADRLDQLAGSLSGGEAQMLAVGRAMMT
RPSLLILDEPSLGLAPKIVDELYDFLGTIRDQQQLSILLVEQAADRALRFADDAYLLSQGRVVASGPAEALREDDQVRSV
YFGGLATS

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0410

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI31657092, Length=235, Percent_Identity=31.4893617021277, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI27436953, Length=214, Percent_Identity=29.4392523364486, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI116734710, Length=218, Percent_Identity=29.3577981651376, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI153792144, Length=209, Percent_Identity=25.8373205741627, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI27477115, Length=231, Percent_Identity=29.8701298701299, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI27262624, Length=220, Percent_Identity=27.7272727272727, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI27262626, Length=220, Percent_Identity=27.7272727272727, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI6005701, Length=210, Percent_Identity=25.7142857142857, Blast_Score=78, Evalue=8e-15,
Organism=Homo sapiens, GI105990541, Length=203, Percent_Identity=27.5862068965517, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI27881501, Length=219, Percent_Identity=28.310502283105, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI30795238, Length=219, Percent_Identity=28.310502283105, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI47078218, Length=206, Percent_Identity=27.1844660194175, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI45446740, Length=206, Percent_Identity=27.1844660194175, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI21536376, Length=229, Percent_Identity=25.764192139738, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI11967969, Length=219, Percent_Identity=28.310502283105, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI9961250, Length=232, Percent_Identity=26.7241379310345, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4505771, Length=232, Percent_Identity=26.7241379310345, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI9961252, Length=232, Percent_Identity=26.7241379310345, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI42741659, Length=162, Percent_Identity=29.0123456790123, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI87082268, Length=239, Percent_Identity=44.3514644351464, Blast_Score=207, Evalue=5e-55,
Organism=Escherichia coli, GI1789864, Length=253, Percent_Identity=31.2252964426877, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1788761, Length=228, Percent_Identity=32.8947368421053, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788225, Length=245, Percent_Identity=33.469387755102, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790525, Length=231, Percent_Identity=29.4372294372294, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789593, Length=240, Percent_Identity=30.4166666666667, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1789672, Length=239, Percent_Identity=28.0334728033473, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994943, Length=224, Percent_Identity=31.25, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI87081709, Length=228, Percent_Identity=27.6315789473684, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787029, Length=224, Percent_Identity=26.3392857142857, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788472, Length=240, Percent_Identity=27.0833333333333, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786872, Length=232, Percent_Identity=27.1551724137931, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790467, Length=219, Percent_Identity=27.8538812785388, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1790162, Length=255, Percent_Identity=26.6666666666667, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788165, Length=235, Percent_Identity=29.3617021276596, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786253, Length=235, Percent_Identity=27.6595744680851, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87081782, Length=224, Percent_Identity=27.6785714285714, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789991, Length=235, Percent_Identity=26.8085106382979, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1786319, Length=226, Percent_Identity=29.646017699115, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI87081791, Length=234, Percent_Identity=27.3504273504274, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787792, Length=238, Percent_Identity=26.890756302521, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1788450, Length=219, Percent_Identity=29.2237442922374, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1790190, Length=230, Percent_Identity=26.0869565217391, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786398, Length=241, Percent_Identity=26.5560165975104, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786563, Length=216, Percent_Identity=28.2407407407407, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789032, Length=229, Percent_Identity=27.5109170305677, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI48994997, Length=236, Percent_Identity=29.6610169491525, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787089, Length=236, Percent_Identity=28.3898305084746, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786981, Length=202, Percent_Identity=36.6336633663366, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787370, Length=238, Percent_Identity=28.1512605042017, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI87081834, Length=212, Percent_Identity=26.8867924528302, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI48995001, Length=232, Percent_Identity=27.5862068965517, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1790544, Length=249, Percent_Identity=26.5060240963855, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788897, Length=227, Percent_Identity=29.0748898678414, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787712, Length=217, Percent_Identity=26.7281105990783, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1790739, Length=249, Percent_Identity=25.7028112449799, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1786703, Length=217, Percent_Identity=28.110599078341, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI1787758, Length=210, Percent_Identity=25.2380952380952, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1788210, Length=215, Percent_Identity=26.5116279069767, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789586, Length=229, Percent_Identity=28.3842794759825, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786803, Length=234, Percent_Identity=21.7948717948718, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1789890, Length=237, Percent_Identity=29.1139240506329, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082267, Length=204, Percent_Identity=26.9607843137255, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787547, Length=233, Percent_Identity=23.6051502145923, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1789963, Length=247, Percent_Identity=29.5546558704453, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788506, Length=244, Percent_Identity=26.6393442622951, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789873, Length=173, Percent_Identity=28.3236994219653, Blast_Score=64, Evalue=8e-12,
Organism=Escherichia coli, GI1787105, Length=234, Percent_Identity=24.7863247863248, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787164, Length=199, Percent_Identity=25.1256281407035, Blast_Score=62, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=227, Percent_Identity=27.7533039647577, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI71983516, Length=210, Percent_Identity=30, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71983510, Length=210, Percent_Identity=30, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI71983523, Length=210, Percent_Identity=30, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115533608, Length=200, Percent_Identity=33, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17565586, Length=214, Percent_Identity=26.1682242990654, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71984940, Length=240, Percent_Identity=26.25, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI212646699, Length=224, Percent_Identity=27.6785714285714, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569143, Length=157, Percent_Identity=29.9363057324841, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193202349, Length=217, Percent_Identity=24.8847926267281, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25146777, Length=213, Percent_Identity=26.7605633802817, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322177, Length=210, Percent_Identity=27.6190476190476, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324585, Length=225, Percent_Identity=25.3333333333333, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323959, Length=227, Percent_Identity=27.7533039647577, Blast_Score=62, Evalue=9e-11,
Organism=Drosophila melanogaster, GI221512771, Length=228, Percent_Identity=28.9473684210526, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24643674, Length=226, Percent_Identity=26.5486725663717, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24648314, Length=228, Percent_Identity=26.3157894736842, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574533, Length=215, Percent_Identity=25.5813953488372, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24582014, Length=191, Percent_Identity=31.413612565445, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24582012, Length=191, Percent_Identity=31.413612565445, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI221500365, Length=234, Percent_Identity=26.9230769230769, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007184, Length=234, Percent_Identity=26.9230769230769, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24666092, Length=229, Percent_Identity=25.764192139738, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28574150, Length=212, Percent_Identity=28.7735849056604, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007328, Length=212, Percent_Identity=28.7735849056604, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24650853, Length=200, Percent_Identity=27, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24650855, Length=200, Percent_Identity=27, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281362751, Length=209, Percent_Identity=27.7511961722488, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573573, Length=235, Percent_Identity=28.0851063829787, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28573571, Length=235, Percent_Identity=28.0851063829787, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI28574744, Length=199, Percent_Identity=26.1306532663317, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281361582, Length=234, Percent_Identity=29.0598290598291, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI28574259, Length=242, Percent_Identity=28.099173553719, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI161076682, Length=221, Percent_Identity=24.8868778280543, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI161076684, Length=221, Percent_Identity=24.8868778280543, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581617, Length=221, Percent_Identity=24.8868778280543, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581615, Length=221, Percent_Identity=24.8868778280543, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI85725262, Length=213, Percent_Identity=25.8215962441315, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21357907, Length=235, Percent_Identity=25.1063829787234, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 26898; Mature: 26767

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTASSDPALLEVSNLRVRFGHVDAVRDVSLAVGRSRVVTLLGPNGAGKTTTLKAICGLL
CCCCCCCCCEEEEECCEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
RPARGEIRINGRRTNGVVASRVTKLGVGLVPEGRRIFPAHTVKENLELGGFIWRRQRPVF
CCCCCEEEECCEECCCHHHHHHHHHCCCCCCCCCEECCHHHHHHCCCCCCEEEECCCCCH
DETLASVLELFPRLADRLDQLAGSLSGGEAQMLAVGRAMMTRPSLLILDEPSLGLAPKIV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHH
DELYDFLGTIRDQQQLSILLVEQAADRALRFADDAYLLSQGRVVASGPAEALREDDQVRS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEHCCCCEEECCCHHHHCCCHHHHH
VYFGGLATS
EEECCCCCC
>Mature Secondary Structure 
TTASSDPALLEVSNLRVRFGHVDAVRDVSLAVGRSRVVTLLGPNGAGKTTTLKAICGLL
CCCCCCCCEEEEECCEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHH
RPARGEIRINGRRTNGVVASRVTKLGVGLVPEGRRIFPAHTVKENLELGGFIWRRQRPVF
CCCCCEEEECCEECCCHHHHHHHHHCCCCCCCCCEECCHHHHHHCCCCCCEEEECCCCCH
DETLASVLELFPRLADRLDQLAGSLSGGEAQMLAVGRAMMTRPSLLILDEPSLGLAPKIV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCHHHH
DELYDFLGTIRDQQQLSILLVEQAADRALRFADDAYLLSQGRVVASGPAEALREDDQVRS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEHCCCCEEECCCHHHHCCCHHHHH
VYFGGLATS
EEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-leucine [Periplasm]; H2O; ATP; L-valine [Periplasm]; L-iso-leucine [Periplasm] [C]

Specific reaction: ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]