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The map label for this gene is mshA

Identifier: 119718269

GI number: 119718269

Start: 4273477

End: 4274853

Strand: Reverse

Name: mshA

Synonym: Noca_4050

Alternate gene names: 119718269

Gene position: 4274853-4273477 (Counterclockwise)

Preceding gene: 119718270

Following gene: 119718268

Centisome position: 85.74

GC content: 74.22

Gene sequence:

>1377_bases
ATGCGCGCTGACCGGCCGGGGCACCGCTCGAGGGGAATCAATCCGGGCCCCGGCATGTTCACCTTGGTTGGACCCGACGA
GCGCGACGACCCCGAGGTGGCAGTGGACCCGATCCGGCGTGTGGCGATGATCAGCCTGCACACCTCGCCCCTCGACCAGC
CCGGGACGGGTGATGCGGGTGGGATGAACGTCTACGTCATCGAGCTGTCCAAGCGACTGGCCGCCCAGGGCATCGCCGTC
GACATCTTCACCCGGGCCACCACCTCGGCGGTCGAGCCGCTGGTCGAGGCGTACGACGGGGTGCAGGTCCGGCACATCCA
CGCCGGGCCGTTCGAGGGGCTCACCAAGGCCGAGCTGCCCGGCCAGCTCTGCGTCTTCGCCCGCGAGGTGCTGCGCGCCG
AGGCGGCCCAGCCGGTCGGGCACTACGACGTCGTGCACTCCCACTACTGGCTCTCCGGGCAGGTCGGCGCGCTGGCCCGC
GACCGGTGGGGTGTGCCGCTGGTGCACTCCATGCACACGATGGCGAAGGTCAAGAACGACGCGCTCGCCGAGGGCGACAC
CCCCGAGCCCGCGGCCCGCATCATCGGCGAGGAGCAGGTCGTCGAGGCCGCCGACATGCTGGTCGCCAACACCGACATCG
AGGCCAAGCAGCTGGTCAACATGTACGACGCCGACCCCAGCCGGGTCGAGGTCGTCCACCCCGGCGTCGACCTCGGGGTG
TTCCGGCCCCAGGACCGCTCGACCGCCCGGGCCCGGCTCGGCCTGCCGGAGGACGCCGCGGTGCTGCTGTTCGCCGGCCG
GATCCAGCCGCTCAAGGCCCCGGACGTGCTGCTGCGCGCCGTCGCCGAGCTGCTCGCCCAGACCCCGGAGCTGCGCTCAC
GGCTGGTCGTCCCGATCGTCGGCGGGCCCTCGGGCTCCGGGCTCGAGCACCCCGAGTCGCTGGCCCAGCTGGCGAGCGAG
CTCGGGCTCGACGGCGCCGGCGGCACCGGCCCCGTGGTGCGCTTCGTGCCTCCGGTCTCCCAGGAGGAGCTGGCCCGCTG
GTGCGCGGCCGCGACCCTGGTCGCGGTGCCGTCGTACAACGAGTCCTTCGGGCTGGTCGCGGCCGAGGCCCAGGCCACCG
GCACCCCGGTCGTCGCCGCCGCGGTCGGCGGCCTCACGACGGTCGTGCGCGACGGCCGCAGCGGCCTGCTCGTCGACACC
CACGACCCGCGGGACTGGGCCGACGCGCTGCGCCGCGTGGTCGAGAACGACGCGTTCCGCGACCGGTTGGCCGCGGGGGC
GCTCGAGCAGGCGCGGCTGTTCTCCTGGGAGCACACCGCGCGGCAGACCCTCGACGTCTACCGGCGGGCGCGGGCCGAGA
TCCGGGAGGCCGTGTGA

Upstream 100 bases:

>100_bases
GCGGTCTTCGGTGCCGCCGCGGTCGTCGTGGCGGCGATCCTGCTCGCCCGCGGCCGGCGTACCGAGCCGACGCCGCCGCC
CCACCGCAACCGCGGCTCGC

Downstream 100 bases:

>100_bases
CGTCGGCGGACGGGGCTCCCGAGCCGGATCCGCGCCAGGTCGTCCGCGACTACCTCGCCGCCAACGACCTCGAGGTGGAG
GAGGTCGCCGACGGCTTCTT

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MRADRPGHRSRGINPGPGMFTLVGPDERDDPEVAVDPIRRVAMISLHTSPLDQPGTGDAGGMNVYVIELSKRLAAQGIAV
DIFTRATTSAVEPLVEAYDGVQVRHIHAGPFEGLTKAELPGQLCVFAREVLRAEAAQPVGHYDVVHSHYWLSGQVGALAR
DRWGVPLVHSMHTMAKVKNDALAEGDTPEPAARIIGEEQVVEAADMLVANTDIEAKQLVNMYDADPSRVEVVHPGVDLGV
FRPQDRSTARARLGLPEDAAVLLFAGRIQPLKAPDVLLRAVAELLAQTPELRSRLVVPIVGGPSGSGLEHPESLAQLASE
LGLDGAGGTGPVVRFVPPVSQEELARWCAAATLVAVPSYNESFGLVAAEAQATGTPVVAAAVGGLTTVVRDGRSGLLVDT
HDPRDWADALRRVVENDAFRDRLAAGALEQARLFSWEHTARQTLDVYRRARAEIREAV

Sequences:

>Translated_458_residues
MRADRPGHRSRGINPGPGMFTLVGPDERDDPEVAVDPIRRVAMISLHTSPLDQPGTGDAGGMNVYVIELSKRLAAQGIAV
DIFTRATTSAVEPLVEAYDGVQVRHIHAGPFEGLTKAELPGQLCVFAREVLRAEAAQPVGHYDVVHSHYWLSGQVGALAR
DRWGVPLVHSMHTMAKVKNDALAEGDTPEPAARIIGEEQVVEAADMLVANTDIEAKQLVNMYDADPSRVEVVHPGVDLGV
FRPQDRSTARARLGLPEDAAVLLFAGRIQPLKAPDVLLRAVAELLAQTPELRSRLVVPIVGGPSGSGLEHPESLAQLASE
LGLDGAGGTGPVVRFVPPVSQEELARWCAAATLVAVPSYNESFGLVAAEAQATGTPVVAAAVGGLTTVVRDGRSGLLVDT
HDPRDWADALRRVVENDAFRDRLAAGALEQARLFSWEHTARQTLDVYRRARAEIREAV
>Mature_458_residues
MRADRPGHRSRGINPGPGMFTLVGPDERDDPEVAVDPIRRVAMISLHTSPLDQPGTGDAGGMNVYVIELSKRLAAQGIAV
DIFTRATTSAVEPLVEAYDGVQVRHIHAGPFEGLTKAELPGQLCVFAREVLRAEAAQPVGHYDVVHSHYWLSGQVGALAR
DRWGVPLVHSMHTMAKVKNDALAEGDTPEPAARIIGEEQVVEAADMLVANTDIEAKQLVNMYDADPSRVEVVHPGVDLGV
FRPQDRSTARARLGLPEDAAVLLFAGRIQPLKAPDVLLRAVAELLAQTPELRSRLVVPIVGGPSGSGLEHPESLAQLASE
LGLDGAGGTGPVVRFVPPVSQEELARWCAAATLVAVPSYNESFGLVAAEAQATGTPVVAAAVGGLTTVVRDGRSGLLVDT
HDPRDWADALRRVVENDAFRDRLAAGALEQARLFSWEHTARQTLDVYRRARAEIREAV

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MSHA_NOCSJ (A1SP12)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_925234.1
- STRING:   A1SP12
- GeneID:   4596564
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_4050
- eggNOG:   COG0438
- HOGENOM:   HBG726846
- OMA:   PLKAPDV
- BioCyc:   NSP35761:NOCA_4050-MONOMER
- HAMAP:   MF_01695
- InterPro:   IPR001296
- InterPro:   IPR017814
- TIGRFAMs:   TIGR03449

Pfam domain/function: PF00534 Glycos_transf_1

EC number: =2.4.1.250

Molecular weight: Translated: 49007; Mature: 49007

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: BINDING 47-47 BINDING 61-61 BINDING 116-116 BINDING 149-149 BINDING 173-173 BINDING 193-193 BINDING 267-267 BINDING 272-272 BINDING 339-339 BINDING 361-361 BINDING 369-369

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRADRPGHRSRGINPGPGMFTLVGPDERDDPEVAVDPIRRVAMISLHTSPLDQPGTGDAG
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCC
GMNVYVIELSKRLAAQGIAVDIFTRATTSAVEPLVEAYDGVQVRHIHAGPFEGLTKAELP
CCEEEEEEEHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHCCC
GQLCVFAREVLRAEAAQPVGHYDVVHSHYWLSGQVGALARDRWGVPLVHSMHTMAKVKND
HHHHHHHHHHHHHHHCCCCCCHHHHHCEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHCC
ALAEGDTPEPAARIIGEEQVVEAADMLVANTDIEAKQLVNMYDADPSRVEVVHPGVDLGV
CCCCCCCCCHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEE
FRPQDRSTARARLGLPEDAAVLLFAGRIQPLKAPDVLLRAVAELLAQTPELRSRLVVPIV
ECCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHCCEEEEEE
GGPSGSGLEHPESLAQLASELGLDGAGGTGPVVRFVPPVSQEELARWCAAATLVAVPSYN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEEECCCC
ESFGLVAAEAQATGTPVVAAAVGGLTTVVRDGRSGLLVDTHDPRDWADALRRVVENDAFR
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCHHHH
DRLAAGALEQARLFSWEHTARQTLDVYRRARAEIREAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRADRPGHRSRGINPGPGMFTLVGPDERDDPEVAVDPIRRVAMISLHTSPLDQPGTGDAG
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHEEEEECCCCCCCCCCCCC
GMNVYVIELSKRLAAQGIAVDIFTRATTSAVEPLVEAYDGVQVRHIHAGPFEGLTKAELP
CCEEEEEEEHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHCCC
GQLCVFAREVLRAEAAQPVGHYDVVHSHYWLSGQVGALARDRWGVPLVHSMHTMAKVKND
HHHHHHHHHHHHHHHCCCCCCHHHHHCEEEECCCCCCHHHCCCCCCHHHHHHHHHHHHCC
ALAEGDTPEPAARIIGEEQVVEAADMLVANTDIEAKQLVNMYDADPSRVEVVHPGVDLGV
CCCCCCCCCHHHHHHCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEEEECCCCCEEE
FRPQDRSTARARLGLPEDAAVLLFAGRIQPLKAPDVLLRAVAELLAQTPELRSRLVVPIV
ECCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHCCEEEEEE
GGPSGSGLEHPESLAQLASELGLDGAGGTGPVVRFVPPVSQEELARWCAAATLVAVPSYN
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHEEECCCC
ESFGLVAAEAQATGTPVVAAAVGGLTTVVRDGRSGLLVDTHDPRDWADALRRVVENDAFR
CCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCHHHH
DRLAAGALEQARLFSWEHTARQTLDVYRRARAEIREAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA