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The map label for this gene is pbuG [H]

Identifier: 119718148

GI number: 119718148

Start: 4134883

End: 4136358

Strand: Reverse

Name: pbuG [H]

Synonym: Noca_3928

Alternate gene names: 119718148

Gene position: 4136358-4134883 (Counterclockwise)

Preceding gene: 119718150

Following gene: 119718147

Centisome position: 82.96

GC content: 68.7

Gene sequence:

>1476_bases
ATGCTGCCGCGCGTGAGTACACAGGCGACGAAGGACCGGAGCGGCCTGGACCGCTACTTCAAGATCACCGAGCGCGGCTC
GACCGTGGAGCGTGAGGTGCGTGGCGGGATCGTCACGTTCTTCACGATGTCCTACATCATCGTGCTGAACCCGCTGATCC
TCGGCTTCGCGCCGGACCAGGACGGCTCGTTCCTCGGCGGGGGGTCCGGTGACGGCTCCAACCTGGCCGCCATCGCGGCC
GGCACCGCCCTGGTCGCCGGCGTGATGACGATCCTGATGGGGGTCGTGGCGAACTACCCGCTCGCGCTCGCGACCGGCCT
GGGCCTCAATGCGTTCGTCGCGTTCTCGGTCGCCAACCAGATGACCTGGGCGGACGCGATGGGCCTGGTGGTCATCGAGG
GCCTGGTGATCCTGGTCCTGGTGCTCACCGGGTTCCGGGAGGCGGTGTTCCACGCGGTGCCGGCCCAGCTCAAGATCGCG
ATCTCGGTCGGGATCGGCCTGTTCATCGCGCTGATCGGGTTCGTCGACGCCGGGTTCGTACGCCGGATCCCCGACGCGGC
GCACAGCACGGTGCCGGTCCAGCTCGGGCAGAACGGCCAGCTGTCCGGCTGGCCGGTCCTGGTCTTCGCGATCGGGCTGG
TGCTCGTCGTCAGCCTGTGGGTGCTCAAGGTGCGGGGCGCGATCCTGATCTCGATCATCGCCACGACCGTGCTCGCGATC
ATCGTCGAGGCGATCGCCGACCTCGGGCCGAGCTCGGAGAACCCGAAGGGCTGGAGCCTCAATGTCCCGTCGTGGCCCGA
CGACATCATCGCGACCCCGCACTTCGACACCCTGGGCGAGTTCAGCCTGCTCGGCTCGTGGGAGAACGCCGGCGTCGTCA
CCGCGCTGCTGCTGATCTTCACGCTGATGCTCGCGGACTTCTTCGACACCATGGGCACGATGACAGCCATCGGCGCCGAG
GCGGGCCTGCTCCAGGAGGACGGCACCCCGCCGGCCACCCGCCGGATCCTCGTGGTCGACTCCCTGGCCGCCGCCGCCGG
TGGCGCCGCGGGCGTGTCCTCGAACACCTCCTACATCGAGTCGGCCTCGGGGGTCGGCGAGGGCGCGCGCACCGGGCTGG
CCTCGATCGTCACCGGCGTGCTGTTCCTGGCCGCGATCTTCGTCGCGCCCGTGGTCGAGATCATCCCGTCCGAGGCCGCG
GTCCCCGCGCTCGTCCTGGTCGGCTTCTTGATGATGCAGCAGGTCAAGGGGATCGACTGGGACGACCTCGAGATCGCGAT
CCCGGCGTTCCTCACCATCGTGCTGATGCCGTTCACCTACTCGATCTCGGTCGGCATCGGCGCCGGCTTCCTCGCGTTCG
TGCTGATCAAGGTGATCCGGGGCCGGTTCGCCGCGGTGCACCCGCTGTTGTGGGTGGTCGCCGCCCTCTTCGCCGTGTAC
TTCGCGATCAACCCGATCACCAACTGGCTCACCTGA

Upstream 100 bases:

>100_bases
CGGCGACGAAGAACGTCCGGCGGCCGAACTCGTGCTGCAGCGGTTGGTTGTCGCGGAACTCCACGCGAGACACGCTAGTC
GACGGTGCCCCGGGTCTGGG

Downstream 100 bases:

>100_bases
CCGACCCGTTCCCTGTCGTCGACCCGCCCGCGGACCTCCCGGGCGGGTCGACGGCATTTCGCGCCCGAAGAGGGAATCGT
TAGCACAGGTAATGAGTTAT

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MLPRVSTQATKDRSGLDRYFKITERGSTVEREVRGGIVTFFTMSYIIVLNPLILGFAPDQDGSFLGGGSGDGSNLAAIAA
GTALVAGVMTILMGVVANYPLALATGLGLNAFVAFSVANQMTWADAMGLVVIEGLVILVLVLTGFREAVFHAVPAQLKIA
ISVGIGLFIALIGFVDAGFVRRIPDAAHSTVPVQLGQNGQLSGWPVLVFAIGLVLVVSLWVLKVRGAILISIIATTVLAI
IVEAIADLGPSSENPKGWSLNVPSWPDDIIATPHFDTLGEFSLLGSWENAGVVTALLLIFTLMLADFFDTMGTMTAIGAE
AGLLQEDGTPPATRRILVVDSLAAAAGGAAGVSSNTSYIESASGVGEGARTGLASIVTGVLFLAAIFVAPVVEIIPSEAA
VPALVLVGFLMMQQVKGIDWDDLEIAIPAFLTIVLMPFTYSISVGIGAGFLAFVLIKVIRGRFAAVHPLLWVVAALFAVY
FAINPITNWLT

Sequences:

>Translated_491_residues
MLPRVSTQATKDRSGLDRYFKITERGSTVEREVRGGIVTFFTMSYIIVLNPLILGFAPDQDGSFLGGGSGDGSNLAAIAA
GTALVAGVMTILMGVVANYPLALATGLGLNAFVAFSVANQMTWADAMGLVVIEGLVILVLVLTGFREAVFHAVPAQLKIA
ISVGIGLFIALIGFVDAGFVRRIPDAAHSTVPVQLGQNGQLSGWPVLVFAIGLVLVVSLWVLKVRGAILISIIATTVLAI
IVEAIADLGPSSENPKGWSLNVPSWPDDIIATPHFDTLGEFSLLGSWENAGVVTALLLIFTLMLADFFDTMGTMTAIGAE
AGLLQEDGTPPATRRILVVDSLAAAAGGAAGVSSNTSYIESASGVGEGARTGLASIVTGVLFLAAIFVAPVVEIIPSEAA
VPALVLVGFLMMQQVKGIDWDDLEIAIPAFLTIVLMPFTYSISVGIGAGFLAFVLIKVIRGRFAAVHPLLWVVAALFAVY
FAINPITNWLT
>Mature_491_residues
MLPRVSTQATKDRSGLDRYFKITERGSTVEREVRGGIVTFFTMSYIIVLNPLILGFAPDQDGSFLGGGSGDGSNLAAIAA
GTALVAGVMTILMGVVANYPLALATGLGLNAFVAFSVANQMTWADAMGLVVIEGLVILVLVLTGFREAVFHAVPAQLKIA
ISVGIGLFIALIGFVDAGFVRRIPDAAHSTVPVQLGQNGQLSGWPVLVFAIGLVLVVSLWVLKVRGAILISIIATTVLAI
IVEAIADLGPSSENPKGWSLNVPSWPDDIIATPHFDTLGEFSLLGSWENAGVVTALLLIFTLMLADFFDTMGTMTAIGAE
AGLLQEDGTPPATRRILVVDSLAAAAGGAAGVSSNTSYIESASGVGEGARTGLASIVTGVLFLAAIFVAPVVEIIPSEAA
VPALVLVGFLMMQQVKGIDWDDLEIAIPAFLTIVLMPFTYSISVGIGAGFLAFVLIKVIRGRFAAVHPLLWVVAALFAVY
FAINPITNWLT

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=479, Percent_Identity=36.5344467640919, Blast_Score=256, Evalue=3e-69,
Organism=Escherichia coli, GI1790150, Length=479, Percent_Identity=35.9081419624217, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI1790499, Length=482, Percent_Identity=31.5352697095436, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI48994909, Length=480, Percent_Identity=31.0416666666667, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 51237; Mature: 51237

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPRVSTQATKDRSGLDRYFKITERGSTVEREVRGGIVTFFTMSYIIVLNPLILGFAPDQ
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCC
DGSFLGGGSGDGSNLAAIAAGTALVAGVMTILMGVVANYPLALATGLGLNAFVAFSVANQ
CCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
MTWADAMGLVVIEGLVILVLVLTGFREAVFHAVPAQLKIAISVGIGLFIALIGFVDAGFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHH
RRIPDAAHSTVPVQLGQNGQLSGWPVLVFAIGLVLVVSLWVLKVRGAILISIIATTVLAI
HHCCCHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVEAIADLGPSSENPKGWSLNVPSWPDDIIATPHFDTLGEFSLLGSWENAGVVTALLLIF
HHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHH
TLMLADFFDTMGTMTAIGAEAGLLQEDGTPPATRRILVVDSLAAAAGGAAGVSSNTSYIE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCEEEEEEHHHHHCCCCCCCCCCCHHHH
SASGVGEGARTGLASIVTGVLFLAAIFVAPVVEIIPSEAAVPALVLVGFLMMQQVKGIDW
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
DDLEIAIPAFLTIVLMPFTYSISVGIGAGFLAFVLIKVIRGRFAAVHPLLWVVAALFAVY
CCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAINPITNWLT
HHHHHHHHCCC
>Mature Secondary Structure
MLPRVSTQATKDRSGLDRYFKITERGSTVEREVRGGIVTFFTMSYIIVLNPLILGFAPDQ
CCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHEECCCC
DGSFLGGGSGDGSNLAAIAAGTALVAGVMTILMGVVANYPLALATGLGLNAFVAFSVANQ
CCCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCHHHHHHHHHHHH
MTWADAMGLVVIEGLVILVLVLTGFREAVFHAVPAQLKIAISVGIGLFIALIGFVDAGFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHHHHHHHHHHHH
RRIPDAAHSTVPVQLGQNGQLSGWPVLVFAIGLVLVVSLWVLKVRGAILISIIATTVLAI
HHCCCHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVEAIADLGPSSENPKGWSLNVPSWPDDIIATPHFDTLGEFSLLGSWENAGVVTALLLIF
HHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHH
TLMLADFFDTMGTMTAIGAEAGLLQEDGTPPATRRILVVDSLAAAAGGAAGVSSNTSYIE
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCEEEEEEHHHHHCCCCCCCCCCCHHHH
SASGVGEGARTGLASIVTGVLFLAAIFVAPVVEIIPSEAAVPALVLVGFLMMQQVKGIDW
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
DDLEIAIPAFLTIVLMPFTYSISVGIGAGFLAFVLIKVIRGRFAAVHPLLWVVAALFAVY
CCHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAINPITNWLT
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]