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The map label for this gene is iolS [H]

Identifier: 119717971

GI number: 119717971

Start: 3969313

End: 3970293

Strand: Reverse

Name: iolS [H]

Synonym: Noca_3749

Alternate gene names: 119717971

Gene position: 3970293-3969313 (Counterclockwise)

Preceding gene: 119717972

Following gene: 119717969

Centisome position: 79.63

GC content: 72.78

Gene sequence:

>981_bases
ATGGAGCAGCGCACCCTCGGCCGGACCGGGCGTCCGGTCTCCGTGGTCGGACTCGGCACCTGGCAGCTCGGCGCGGACTG
GGGGGACGTCTCCGAGGACGACGCCCTCGCCGTCCTCGGCGCCTCGGTCGACGCCGGTGTCACGTTCTTCGACACCGCCG
ACGTGTACGGCGACGGGCGCAGCGAACAGGTGATCGGCCGGTTCCTGCGCGAGCACCCCGAGGTCGTCGTGGCCACCAAG
ATGGGTCGTCGCGTCGAGCAGCTGCCCGAGCACTACACGCTCGAGAGCTTCCGGGCCTGGACCGACCGGTCGCGACGCAA
CCTCGGCGTCGACACCCTCGACCTCGTGCAGCTGCACTGCCCCCCGAGCGCGGTCATCGACGCGGACGCGACGTACGACG
CGCTCGACACGCTGGTCGCCGACGGCGCGATCGCGGCGTACGGCGTGAGCGTCGAGACCGTCGACCAGGCATTGTCCGCC
ATCGCGCGCCCGCACGTCGCGTCGATCCAGATCATCCTCAACGCGTTCCGCCTCAAGCCGTTGGACCGGGTGCTGCCGGC
GGCGGCGGAGGCCGGGGTCGCGATCATCGCCCGGGTGCCGCTCGCGTCCGGCCTGTTGTCGGGTCGCTACGACGAGCACA
CGACGTTCGCCCCGGACGACCACCGCAGCTACAACCGCGACGGCAGCGCCTTCGACGTGGGGGAGACGTTCTCGGGCGTC
GACTACGAGACCGGCGTCCGCGCGGCGCAGGAGTTCTCGCAGCTGGTGCGTGACCTGGACCTGACGCCCGCGCAGGCGGC
GATCGCGTGGGTGGTGCAGCAGCCGGGCGTCACCACGGTGATCCCGGGCGCCCGCAACGCCGAGCAGGCGCGCGCCAACG
CGGTCGCCGGACTGGCCGGGCCGCTGCCCGGCTCCGTCCTGGACGGGGTCACGCGGATCTACGACACGAGGCTCCGCGCG
GCGATCCACGACCGCTGGTAG

Upstream 100 bases:

>100_bases
CCCGCACCGACGACTACGTGCCCGGCAAGCACCGGCTCTCGCGGAAGGTGCTCTCCTACCTCCCTGGGTGAGGCCCGAGA
CCGCGTGCCAGACTCGCGGC

Downstream 100 bases:

>100_bases
CCGCGTCTGCCGCGTCGGCTTCGCCGCCACACCCGCCGAGGCCGCGTCTGCGGCGTCGGCTTCGCCGCCGCGCCGGCCGC
GGGATCTTTCCTGGGTCGGT

Product: aldo/keto reductase

Products: NA

Alternate protein names: AKR11A; Vegetative protein 147; VEG147 [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MEQRTLGRTGRPVSVVGLGTWQLGADWGDVSEDDALAVLGASVDAGVTFFDTADVYGDGRSEQVIGRFLREHPEVVVATK
MGRRVEQLPEHYTLESFRAWTDRSRRNLGVDTLDLVQLHCPPSAVIDADATYDALDTLVADGAIAAYGVSVETVDQALSA
IARPHVASIQIILNAFRLKPLDRVLPAAAEAGVAIIARVPLASGLLSGRYDEHTTFAPDDHRSYNRDGSAFDVGETFSGV
DYETGVRAAQEFSQLVRDLDLTPAQAAIAWVVQQPGVTTVIPGARNAEQARANAVAGLAGPLPGSVLDGVTRIYDTRLRA
AIHDRW

Sequences:

>Translated_326_residues
MEQRTLGRTGRPVSVVGLGTWQLGADWGDVSEDDALAVLGASVDAGVTFFDTADVYGDGRSEQVIGRFLREHPEVVVATK
MGRRVEQLPEHYTLESFRAWTDRSRRNLGVDTLDLVQLHCPPSAVIDADATYDALDTLVADGAIAAYGVSVETVDQALSA
IARPHVASIQIILNAFRLKPLDRVLPAAAEAGVAIIARVPLASGLLSGRYDEHTTFAPDDHRSYNRDGSAFDVGETFSGV
DYETGVRAAQEFSQLVRDLDLTPAQAAIAWVVQQPGVTTVIPGARNAEQARANAVAGLAGPLPGSVLDGVTRIYDTRLRA
AIHDRW
>Mature_326_residues
MEQRTLGRTGRPVSVVGLGTWQLGADWGDVSEDDALAVLGASVDAGVTFFDTADVYGDGRSEQVIGRFLREHPEVVVATK
MGRRVEQLPEHYTLESFRAWTDRSRRNLGVDTLDLVQLHCPPSAVIDADATYDALDTLVADGAIAAYGVSVETVDQALSA
IARPHVASIQIILNAFRLKPLDRVLPAAAEAGVAIIARVPLASGLLSGRYDEHTTFAPDDHRSYNRDGSAFDVGETFSGV
DYETGVRAAQEFSQLVRDLDLTPAQAAIAWVVQQPGVTTVIPGARNAEQARANAVAGLAGPLPGSVLDGVTRIYDTRLRA
AIHDRW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=27.7070063694268, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI4504825, Length=311, Percent_Identity=27.6527331189711, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=28.0645161290323, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI27436964, Length=310, Percent_Identity=25.1612903225806, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=25.4019292604502, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI27436962, Length=310, Percent_Identity=25.1612903225806, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI87081735, Length=304, Percent_Identity=30.2631578947368, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789375, Length=316, Percent_Identity=26.2658227848101, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788070, Length=316, Percent_Identity=25.9493670886076, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=31.2217194570136, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24646155, Length=163, Percent_Identity=31.9018404907975, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34967; Mature: 34967

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQRTLGRTGRPVSVVGLGTWQLGADWGDVSEDDALAVLGASVDAGVTFFDTADVYGDGR
CCCCCCCCCCCCEEEEEECEEEECCCCCCCCCCCCEEEEECCCCCCEEEEECCHHCCCCC
SEQVIGRFLREHPEVVVATKMGRRVEQLPEHYTLESFRAWTDRSRRNLGVDTLDLVQLHC
HHHHHHHHHHHCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
PPSAVIDADATYDALDTLVADGAIAAYGVSVETVDQALSAIARPHVASIQIILNAFRLKP
CCCCEEECCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCH
LDRVLPAAAEAGVAIIARVPLASGLLSGRYDEHTTFAPDDHRSYNRDGSAFDVGETFSGV
HHHHHHHHHHCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
DYETGVRAAQEFSQLVRDLDLTPAQAAIAWVVQQPGVTTVIPGARNAEQARANAVAGLAG
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCC
PLPGSVLDGVTRIYDTRLRAAIHDRW
CCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEQRTLGRTGRPVSVVGLGTWQLGADWGDVSEDDALAVLGASVDAGVTFFDTADVYGDGR
CCCCCCCCCCCCEEEEEECEEEECCCCCCCCCCCCEEEEECCCCCCEEEEECCHHCCCCC
SEQVIGRFLREHPEVVVATKMGRRVEQLPEHYTLESFRAWTDRSRRNLGVDTLDLVQLHC
HHHHHHHHHHHCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEEC
PPSAVIDADATYDALDTLVADGAIAAYGVSVETVDQALSAIARPHVASIQIILNAFRLKP
CCCCEEECCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCH
LDRVLPAAAEAGVAIIARVPLASGLLSGRYDEHTTFAPDDHRSYNRDGSAFDVGETFSGV
HHHHHHHHHHCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCC
DYETGVRAAQEFSQLVRDLDLTPAQAAIAWVVQQPGVTTVIPGARNAEQARANAVAGLAG
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCC
PLPGSVLDGVTRIYDTRLRAAIHDRW
CCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584049; 9384377; 9298659 [H]