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The map label for this gene is dinB2 [H]

Identifier: 119717925

GI number: 119717925

Start: 3930069

End: 3931157

Strand: Reverse

Name: dinB2 [H]

Synonym: Noca_3703

Alternate gene names: 119717925

Gene position: 3931157-3930069 (Counterclockwise)

Preceding gene: 119717926

Following gene: 119717922

Centisome position: 78.85

GC content: 74.47

Gene sequence:

>1089_bases
ATGAGCGGCCGGACCGCACCGGGCTGGGTGCTGCACGTCGACCTGGACCAGTTCATCGCCGCGGTCGAGGTGCTGCGCCG
GCCGGAGCTGGCTGGCCGCCCGGTGGTCGTCGGCGGCCGTGGCGATCCGACCGAGCGTGGGGTGGTCGCGACCGCGTCGT
ACGAGGCGCGGGCGTTCGGGGTCGGGTCCGGCATGCCGTTGCGGGTCGCGGCCCGCAAGTGCCCCGACGCGGTCTTCCTG
CCGGTCGACAAGGAGGCGTACGACGCCGCCTCGGCGCAGGTGATGACGACGCTGCGCGGCCTGGAGTGGGGCGGCGTACC
GGTCGTGCTCGAGGTGCTCGGCTGGGACGAGGCGTTCCTGGCGGCGGGCGAGGACCACGGCGAGCTCGGCAACCCCCGGG
AGTTCGCCGAGCACCTGCGCGCCGAGGTGCTCGCCGAGACCCGACTGCACTGCTCGGTCGGGATCGGCGACAACAAGCTG
CGCGCGAAGATCGCCACCGACTTCGGCAAGCCCCGCGGGGTGTGGCAGCTGACCGAGGCGGACTGGTTCCCGGTGATGGG
GGAGCGGCCGACGACCGCGCTCTGGGGCATCGGCGCCCGGACCGCGAAGAAGCTGTCCGCGCTCGGCATCGACACCGTGG
AGCAGCTGGCCCGATCCGACGCCCGCGTCCTCGCCGCCGAGCTCGGGCCGACGATGGGCCCGTGGTTCCACCGGCTCGGC
CGCGGGGTCGACACCAGCCCCGTCGACGCGACGCCGTGGGTGCCGCGGGCACACGGGCGGGAGGAGACCTACCAGGAGGA
CCTCGAGGACTGGGACCGGGTCACCGAGGAGGTCCGGGCGCTGACCCGGAGGGTGGTCGACGACATCGACCGCGAGGGGC
GTCCGGCCGCGCGGGTGGGGATCAAGGTCCGCTACCGGCCGTTCAGCACGGTCAGCCGCAGCCTCACCCTGCCCGAGCCG
AGCAACGATCCGGCCGTGCTGGAGGACGCCGCCGTCTCGTTGCTGGAGCGCGTGGAGCGCGGCCGACCCGTCCGCCTGCT
CGGCGTGCGCCTCGAGATGGTCGACCCGCCCGAAGGACCGCTGCGCTGA

Upstream 100 bases:

>100_bases
AGGCGATCCTGGCCCAGCTGCGGGCGGTCGTCGCGGACCTCCTGATGGTCACCGGGCTCGACCAGATGGAGTCGACCGAG
GCCCTGCCCCCGCCACCGCG

Downstream 100 bases:

>100_bases
ACGGGTCGTGTGCCTGAGAACGCGCCATGGCGCGTCCTCAGGCACACGACCCGAAAGTTCCGGGCGCCTCAGCCCAGGCC
GGCGCGCAGCTCGCGGACGA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 2 [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MSGRTAPGWVLHVDLDQFIAAVEVLRRPELAGRPVVVGGRGDPTERGVVATASYEARAFGVGSGMPLRVAARKCPDAVFL
PVDKEAYDAASAQVMTTLRGLEWGGVPVVLEVLGWDEAFLAAGEDHGELGNPREFAEHLRAEVLAETRLHCSVGIGDNKL
RAKIATDFGKPRGVWQLTEADWFPVMGERPTTALWGIGARTAKKLSALGIDTVEQLARSDARVLAAELGPTMGPWFHRLG
RGVDTSPVDATPWVPRAHGREETYQEDLEDWDRVTEEVRALTRRVVDDIDREGRPAARVGIKVRYRPFSTVSRSLTLPEP
SNDPAVLEDAAVSLLERVERGRPVRLLGVRLEMVDPPEGPLR

Sequences:

>Translated_362_residues
MSGRTAPGWVLHVDLDQFIAAVEVLRRPELAGRPVVVGGRGDPTERGVVATASYEARAFGVGSGMPLRVAARKCPDAVFL
PVDKEAYDAASAQVMTTLRGLEWGGVPVVLEVLGWDEAFLAAGEDHGELGNPREFAEHLRAEVLAETRLHCSVGIGDNKL
RAKIATDFGKPRGVWQLTEADWFPVMGERPTTALWGIGARTAKKLSALGIDTVEQLARSDARVLAAELGPTMGPWFHRLG
RGVDTSPVDATPWVPRAHGREETYQEDLEDWDRVTEEVRALTRRVVDDIDREGRPAARVGIKVRYRPFSTVSRSLTLPEP
SNDPAVLEDAAVSLLERVERGRPVRLLGVRLEMVDPPEGPLR
>Mature_361_residues
SGRTAPGWVLHVDLDQFIAAVEVLRRPELAGRPVVVGGRGDPTERGVVATASYEARAFGVGSGMPLRVAARKCPDAVFLP
VDKEAYDAASAQVMTTLRGLEWGGVPVVLEVLGWDEAFLAAGEDHGELGNPREFAEHLRAEVLAETRLHCSVGIGDNKLR
AKIATDFGKPRGVWQLTEADWFPVMGERPTTALWGIGARTAKKLSALGIDTVEQLARSDARVLAAELGPTMGPWFHRLGR
GVDTSPVDATPWVPRAHGREETYQEDLEDWDRVTEEVRALTRRVVDDIDREGRPAARVGIKVRYRPFSTVSRSLTLPEPS
NDPAVLEDAAVSLLERVERGRPVRLLGVRLEMVDPPEGPLR

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=419, Percent_Identity=24.582338902148, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI7706681, Length=420, Percent_Identity=24.7619047619048, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI7705344, Length=118, Percent_Identity=33.0508474576271, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1786425, Length=353, Percent_Identity=30.028328611898, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1787432, Length=358, Percent_Identity=28.2122905027933, Blast_Score=95, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI193205700, Length=411, Percent_Identity=27.2506082725061, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17537959, Length=248, Percent_Identity=29.8387096774194, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI193205702, Length=298, Percent_Identity=28.8590604026846, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19923006, Length=287, Percent_Identity=26.4808362369338, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39589; Mature: 39458

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50173 UMUC ; PS00048 PROTAMINE_P1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGRTAPGWVLHVDLDQFIAAVEVLRRPELAGRPVVVGGRGDPTERGVVATASYEARAFG
CCCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEECCCCEEEE
VGSGMPLRVAARKCPDAVFLPVDKEAYDAASAQVMTTLRGLEWGGVPVVLEVLGWDEAFL
CCCCCCEEHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
AAGEDHGELGNPREFAEHLRAEVLAETRLHCSVGIGDNKLRAKIATDFGKPRGVWQLTEA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHEEEEHHCCCCCCCEEEECCC
DWFPVMGERPTTALWGIGARTAKKLSALGIDTVEQLARSDARVLAAELGPTMGPWFHRLG
CCCCCCCCCCCHHEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
RGVDTSPVDATPWVPRAHGREETYQEDLEDWDRVTEEVRALTRRVVDDIDREGRPAARVG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEE
IKVRYRPFSTVSRSLTLPEPSNDPAVLEDAAVSLLERVERGRPVRLLGVRLEMVDPPEGP
EEEEECCHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCC
LR
CC
>Mature Secondary Structure 
SGRTAPGWVLHVDLDQFIAAVEVLRRPELAGRPVVVGGRGDPTERGVVATASYEARAFG
CCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCCEEEEECCCCEEEE
VGSGMPLRVAARKCPDAVFLPVDKEAYDAASAQVMTTLRGLEWGGVPVVLEVLGWDEAFL
CCCCCCEEHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHH
AAGEDHGELGNPREFAEHLRAEVLAETRLHCSVGIGDNKLRAKIATDFGKPRGVWQLTEA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCHHEEEEHHCCCCCCCEEEECCC
DWFPVMGERPTTALWGIGARTAKKLSALGIDTVEQLARSDARVLAAELGPTMGPWFHRLG
CCCCCCCCCCCHHEECCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
RGVDTSPVDATPWVPRAHGREETYQEDLEDWDRVTEEVRALTRRVVDDIDREGRPAARVG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEE
IKVRYRPFSTVSRSLTLPEPSNDPAVLEDAAVSLLERVERGRPVRLLGVRLEMVDPPEGP
EEEEECCHHHHHCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCC
LR
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]