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The map label for this gene is purN [H]

Identifier: 119717806

GI number: 119717806

Start: 3801758

End: 3802384

Strand: Reverse

Name: purN [H]

Synonym: Noca_3584

Alternate gene names: 119717806

Gene position: 3802384-3801758 (Counterclockwise)

Preceding gene: 119717807

Following gene: 119717805

Centisome position: 76.26

GC content: 73.37

Gene sequence:

>627_bases
GTGACCCCACGCCGCCCCGCTCGTCTCGTGGTGCTCGTGTCCGGGTCCGGGACCAACCTCCAGGCGTTGCTCGACGCGTG
CGCCGACCCGTCGTACGGCGCCCGCGTCGTCGCCGTGGGCGCCGACCGCGACGACATCGAGGGACTCGCCCGCGCGGATC
GGGCCGGCGTGCCGACGTTCGTGCGGAAGGTCGGGCAGTTCACCAGCCGCGAGCACTGGGACCGGGCCCTCGCGGACACG
GTCGCCGGCTTCGAGCCCGACCTGGTCGTGCTTGCCGGGTTCATGAAGCTGGTGGGGGCCGAGTTCCTGACCCGGCTCGG
CGGCCGGGTCGTCAACACCCACCCCGCGCTGTCCCCGTCCTTCCCCGGCATGCACGGTCCGGCCGATGCCCTCGCGTACG
GCGTCAAGGTGACCGGGTGCACGCTGTTCGTGGTCGACGACGGGGTCGACACCGGCCCGATCGTCGCCCAGCGAGCCGTG
CCGGTCGAGGACGACGACACCGTCGAGACGCTGCACGAGCGGATCAAGGTCGCCGAGCGCGCGATGCTGGTCGACACGGT
CGGCCGGATGGCCCGGGCCGGCTGGACCGTCGAGGGCCGGCGCACTCGGTTCGGTGACGAGACCTGA

Upstream 100 bases:

>100_bases
ACGCGATCACCGCCTTCGGCCTCGGCGGCCTGGTCGGCGGCGTTCTCATGACCTGGTGGCAGCGTCGGACCCATCGCCGC
GGTTCCCTAGAATCCACCGC

Downstream 100 bases:

>100_bases
CGGTCCTATGCTGGACTCCACACGACTGGCGCGGGTGGGTGACCACCGGGGAGTGACGCACGGAGCATCGACCGCCTGGG
TGCTCCCCCTTCCGAGCAGG

Product: phosphoribosylglycinamide formyltransferase

Products: NA

Alternate protein names: 5'-phosphoribosylglycinamide transformylase; GAR transformylase; GART [H]

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MTPRRPARLVVLVSGSGTNLQALLDACADPSYGARVVAVGADRDDIEGLARADRAGVPTFVRKVGQFTSREHWDRALADT
VAGFEPDLVVLAGFMKLVGAEFLTRLGGRVVNTHPALSPSFPGMHGPADALAYGVKVTGCTLFVVDDGVDTGPIVAQRAV
PVEDDDTVETLHERIKVAERAMLVDTVGRMARAGWTVEGRRTRFGDET

Sequences:

>Translated_208_residues
MTPRRPARLVVLVSGSGTNLQALLDACADPSYGARVVAVGADRDDIEGLARADRAGVPTFVRKVGQFTSREHWDRALADT
VAGFEPDLVVLAGFMKLVGAEFLTRLGGRVVNTHPALSPSFPGMHGPADALAYGVKVTGCTLFVVDDGVDTGPIVAQRAV
PVEDDDTVETLHERIKVAERAMLVDTVGRMARAGWTVEGRRTRFGDET
>Mature_207_residues
TPRRPARLVVLVSGSGTNLQALLDACADPSYGARVVAVGADRDDIEGLARADRAGVPTFVRKVGQFTSREHWDRALADTV
AGFEPDLVVLAGFMKLVGAEFLTRLGGRVVNTHPALSPSFPGMHGPADALAYGVKVTGCTLFVVDDGVDTGPIVAQRAVP
VEDDDTVETLHERIKVAERAMLVDTVGRMARAGWTVEGRRTRFGDET

Specific function: De novo purine biosynthesis; third step. [C]

COG id: COG0299

COG function: function code F; Folate-dependent phosphoribosylglycinamide formyltransferase PurN

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GART family [H]

Homologues:

Organism=Homo sapiens, GI4503915, Length=180, Percent_Identity=41.6666666666667, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI209869995, Length=180, Percent_Identity=41.6666666666667, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI209869993, Length=180, Percent_Identity=41.6666666666667, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1788846, Length=193, Percent_Identity=36.7875647668394, Blast_Score=135, Evalue=1e-33,
Organism=Escherichia coli, GI1787483, Length=202, Percent_Identity=28.2178217821782, Blast_Score=89, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17567511, Length=182, Percent_Identity=39.010989010989, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320616, Length=209, Percent_Identity=29.1866028708134, Blast_Score=87, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582400, Length=194, Percent_Identity=43.8144329896907, Blast_Score=152, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002376
- InterPro:   IPR001555
- InterPro:   IPR004607 [H]

Pfam domain/function: PF00551 Formyl_trans_N [H]

EC number: =2.1.2.2 [H]

Molecular weight: Translated: 22197; Mature: 22065

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRRPARLVVLVSGSGTNLQALLDACADPSYGARVVAVGADRDDIEGLARADRAGVPTF
CCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCHH
VRKVGQFTSREHWDRALADTVAGFEPDLVVLAGFMKLVGAEFLTRLGGRVVNTHPALSPS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
FPGMHGPADALAYGVKVTGCTLFVVDDGVDTGPIVAQRAVPVEDDDTVETLHERIKVAER
CCCCCCCHHHHHHCEEEECEEEEEEECCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHH
AMLVDTVGRMARAGWTVEGRRTRFGDET
HHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TPRRPARLVVLVSGSGTNLQALLDACADPSYGARVVAVGADRDDIEGLARADRAGVPTF
CCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHCCCCCCHH
VRKVGQFTSREHWDRALADTVAGFEPDLVVLAGFMKLVGAEFLTRLGGRVVNTHPALSPS
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCC
FPGMHGPADALAYGVKVTGCTLFVVDDGVDTGPIVAQRAVPVEDDDTVETLHERIKVAER
CCCCCCCHHHHHHCEEEECEEEEEEECCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHH
AMLVDTVGRMARAGWTVEGRRTRFGDET
HHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3301838; 9205837; 9278503; 10954745; 2204419; 1522592; 1631098; 9698564; 10606510 [H]