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The map label for this gene is frdB [H]

Identifier: 119717769

GI number: 119717769

Start: 3760547

End: 3761323

Strand: Reverse

Name: frdB [H]

Synonym: Noca_3547

Alternate gene names: 119717769

Gene position: 3761323-3760547 (Counterclockwise)

Preceding gene: 119717770

Following gene: 119717768

Centisome position: 75.44

GC content: 68.73

Gene sequence:

>777_bases
ATGGGCTACACGCTGAAGATGCGGATCTGGCGCGGCGACCAGGACGGCGGCGACCTCGGCGACTACGACGTCGAGGTCTC
CGAGGGCGAGGTCGTCCTCGACGCCATCCACCGGGTGCAGGCGACCCAGGCCGGTGACCTCGCCGTCCGCTGGAACTGCA
AGGCCGGCAAGTGCGGCTCCTGCAGCGCCGAGGTGAACGGTCGCCCACGCCTGATGTGCATGACCCGGCTCTCCGACTTC
GACCCGGCCGAGACCATCACGGTCACCCCGATGCGGTCCTTCCCGGTGATCCGCGACCTGGTCACCGACGTGTCCTTCAA
CTACGAGAAGGCCCGCGAGCTGCCGTCGTTCGCGCCGCCGCCACGCGATGCGGACGGCAAGCGCCGGATGGCCCAGGTCG
ACGTCGAGCGCGGCCAGGAGTTCCGCAAGTGCATCGAGTGCTTCCTGTGCCAGAACACCTGCCACGTGATCCGCGACCAC
GAGGAGAACAAGCCCGCCTTCGCCGGGCCCCGGTTCTTCCTGCGGTACGCCGAGCTCGACATGCACCCGCTCGACACCCA
CGACCGCCGCGCGCTCGCCCAGGCCGCAGCCGGCCTCGGGATGTGCAACATCACCAAGTGCTGCACCGAGGTGTGCCCCG
AGGGGATCCGGATCACCGACAACGCGATCATCCCGATGAAGGAGCGGGTCGTGGACCGCAAGTACGACCCGCTGGTCTGG
CTCGGCAGCAAGATCGGCATCCGCAACCGCGACAACGACGGGCGCAGCGAGCTGTAG

Upstream 100 bases:

>100_bases
CTCCGGCTGGCCGCCGACCGCACCGGCGTCGACCTCGCCCACCAGCCGCTCCCGGCGATGCCGGACGAGCTCAAGAAGTT
CTTCGAGTGAAGGGGCCGTC

Downstream 100 bases:

>100_bases
CGCAGGCCCAACGTCCGCGTCGGAGGGGCCCTGCGCCGCTTCTCGGCGGCGCCGTTCCGGCCCACGATGGAGCATGACGG
CAACGAGGGGTGTGCGCACG

Product: fumarate reductase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MGYTLKMRIWRGDQDGGDLGDYDVEVSEGEVVLDAIHRVQATQAGDLAVRWNCKAGKCGSCSAEVNGRPRLMCMTRLSDF
DPAETITVTPMRSFPVIRDLVTDVSFNYEKARELPSFAPPPRDADGKRRMAQVDVERGQEFRKCIECFLCQNTCHVIRDH
EENKPAFAGPRFFLRYAELDMHPLDTHDRRALAQAAAGLGMCNITKCCTEVCPEGIRITDNAIIPMKERVVDRKYDPLVW
LGSKIGIRNRDNDGRSEL

Sequences:

>Translated_258_residues
MGYTLKMRIWRGDQDGGDLGDYDVEVSEGEVVLDAIHRVQATQAGDLAVRWNCKAGKCGSCSAEVNGRPRLMCMTRLSDF
DPAETITVTPMRSFPVIRDLVTDVSFNYEKARELPSFAPPPRDADGKRRMAQVDVERGQEFRKCIECFLCQNTCHVIRDH
EENKPAFAGPRFFLRYAELDMHPLDTHDRRALAQAAAGLGMCNITKCCTEVCPEGIRITDNAIIPMKERVVDRKYDPLVW
LGSKIGIRNRDNDGRSEL
>Mature_257_residues
GYTLKMRIWRGDQDGGDLGDYDVEVSEGEVVLDAIHRVQATQAGDLAVRWNCKAGKCGSCSAEVNGRPRLMCMTRLSDFD
PAETITVTPMRSFPVIRDLVTDVSFNYEKARELPSFAPPPRDADGKRRMAQVDVERGQEFRKCIECFLCQNTCHVIRDHE
ENKPAFAGPRFFLRYAELDMHPLDTHDRRALAQAAAGLGMCNITKCCTEVCPEGIRITDNAIIPMKERVVDRKYDPLVWL
GSKIGIRNRDNDGRSEL

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=221, Percent_Identity=28.9592760180996, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1790596, Length=200, Percent_Identity=30.5, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1786943, Length=240, Percent_Identity=27.5, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17533915, Length=201, Percent_Identity=23.3830845771144, Blast_Score=66, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322987, Length=220, Percent_Identity=25, Blast_Score=86, Evalue=5e-18,
Organism=Drosophila melanogaster, GI17137106, Length=220, Percent_Identity=25.4545454545455, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24643156, Length=241, Percent_Identity=26.9709543568465, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29100; Mature: 28968

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYTLKMRIWRGDQDGGDLGDYDVEVSEGEVVLDAIHRVQATQAGDLAVRWNCKAGKCGS
CCEEEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
CSAEVNGRPRLMCMTRLSDFDPAETITVTPMRSFPVIRDLVTDVSFNYEKARELPSFAPP
CCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCC
PRDADGKRRMAQVDVERGQEFRKCIECFLCQNTCHVIRDHEENKPAFAGPRFFLRYAELD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHEEEEHHCC
MHPLDTHDRRALAQAAAGLGMCNITKCCTEVCPEGIRITDNAIIPMKERVVDRKYDPLVW
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCCCEEE
LGSKIGIRNRDNDGRSEL
ECCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
GYTLKMRIWRGDQDGGDLGDYDVEVSEGEVVLDAIHRVQATQAGDLAVRWNCKAGKCGS
CEEEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCC
CSAEVNGRPRLMCMTRLSDFDPAETITVTPMRSFPVIRDLVTDVSFNYEKARELPSFAPP
CCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCC
PRDADGKRRMAQVDVERGQEFRKCIECFLCQNTCHVIRDHEENKPAFAGPRFFLRYAELD
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHEEEEHHCC
MHPLDTHDRRALAQAAAGLGMCNITKCCTEVCPEGIRITDNAIIPMKERVVDRKYDPLVW
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCCHHHHHHCCCCCCEEE
LGSKIGIRNRDNDGRSEL
ECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]