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The map label for this gene is gatA [H]

Identifier: 119717658

GI number: 119717658

Start: 3642248

End: 3643768

Strand: Reverse

Name: gatA [H]

Synonym: Noca_3436

Alternate gene names: 119717658

Gene position: 3643768-3642248 (Counterclockwise)

Preceding gene: 119717659

Following gene: 119717657

Centisome position: 73.08

GC content: 73.96

Gene sequence:

>1521_bases
ATGTCGATCATCCGCCGCACCGCCGCCGAGATCGCCGACGCGCTCGCCGCGGGCGAGACCACCTCGGCCGAGGTCACCCG
GACGCACCTGGACCGCATCGCCGCCGTCGACGGCGCGGTGCACGCGTTCCTCCACGTCGACGCCGAGGGGGCGCTCGCGC
AGGCGGCCGAGTCCGACGCCCGCCGCGCGGCCGGCACCCCGCTCTCCCCGCTGGACGGCGTGCCGATCGCCGTCAAGGAC
GTGCTGGCCACCGAGGGCCTGCCCACGACCTGCGGCTCGAAGATCCTCGAGGGCTGGATCCCGCCGTACGACGCCACCGC
GGTCGCGAGGCTGCGCGCCGCCGGCCTGCCGATCCTCGGCAAGACCAACATGGACGAGTTCGCGATGGGCTCCTCGACCG
AGCACTCCGCGTACGGCCCCACGCACAACCCGTGGGACCTGGACCGGATCCCCGGCGGCTCCGGCGGAGGCTCGGCGGCG
GCGGTTGCCGCGTTCGAGGCGCCGCTGGCGCTCGGCACCGACACCGGCGGCTCGATCCGCCAGCCCGGCGCCGTGACCGG
CACGGTCGGCGTCAAGCCGACCTACGGCGGGGTGTCGCGCTACGGCCTGGTCGCGCTCGCGAACTCGCTGGACCAGGTCG
GCCCGGTGACCCGGACCGTGCTCGACTCCGCGCTGCTGCACGAGGTCATCGGCGGCCACGACCCGCGAGACTCCACCAGC
ATCGACCAGCCGCTGCCGTCCCTGGTCGAAGCCGCCCGGCTCGGCGCCACCGGCGACCTCTCGGGGCTGCGGGTCGGCGT
GATCACCGAGCTCGCCGGCGACGGGTGGCAGCCGGGCGTGATGGCCCGCTTCCAGGAGTCGGTGGACCTGCTGGTCAAGG
CCGGCGCCGAGGTCGTCGAGGTCTCGTGCCCGACGTTCGTGCACGCCCTGGCGACCTACTACCTGATCCTGCCGGCCGAG
GCGTCGAGCAACCTCGCGAAGTTCGACGCGATGCGCTACGGCCTGCGGGTCTGGCCCGAGGGCCGTCCCGACGCGAGCGC
CGAGGAGGTGATGCGCGCGACCCGCGACGCCGGCTTCGGCCCGGAGGTCAAGCGCCGGATCATCCTCGGCACCTACGCCC
TCTCCAGCGGCTACTACGACGCCTACTACGGCCAGGCGCAGAAGGTGCGCACGCTGATCTCGCGCGACTTCGACGCCGCG
TTCGCGAAGGCCGACGTGCTGGTCTCGCCGACCGCCCCGACGACGGCGTTCAAGCTCGGGGAGAAGCTCGACGACCCGCT
CGCGATGTACCTCAACGACCTCGCGACGATCCCGGCCAACCTCGCCGGCGTGCCCGGCATCTCGGTCCCCAGCGGCCTTG
CCGATGAGGACGGCCTGCCCGCGGGCTTCCAGATCCTGGCGCCCGCGCTCGCCGACGACCGCTGCTACCGCGTCGGCGCC
GCCCTCGAGGCGCTGCTCCACGACCAGTGGGGTGGACCCCTGCTCGACAAGGCCCCCGCTCTGGAAGGAGCACGCCCGTG
A

Upstream 100 bases:

>100_bases
TCGTGGTGCCCGGACTGACCCCGGAGCAGGCGCTGTCGGGCGCCCCCGAGGTCGAGCAGCAGCGCTTCTCGGTGCCGCGG
ATCCTGGGCGAGGAGGCCTG

Downstream 100 bases:

>100_bases
CCGAGACCCTCGTCGCCTTCGACGACGTCCTGGCCTCCTACGACCCGGCGATGGGCCTGGAGGTCCACGTCGAGCTGAAC
ACCGCCTCGAAGATGTTCTG

Product: aspartyl/glutamyl-tRNA amidotransferase subunit A

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 506; Mature: 505

Protein sequence:

>506_residues
MSIIRRTAAEIADALAAGETTSAEVTRTHLDRIAAVDGAVHAFLHVDAEGALAQAAESDARRAAGTPLSPLDGVPIAVKD
VLATEGLPTTCGSKILEGWIPPYDATAVARLRAAGLPILGKTNMDEFAMGSSTEHSAYGPTHNPWDLDRIPGGSGGGSAA
AVAAFEAPLALGTDTGGSIRQPGAVTGTVGVKPTYGGVSRYGLVALANSLDQVGPVTRTVLDSALLHEVIGGHDPRDSTS
IDQPLPSLVEAARLGATGDLSGLRVGVITELAGDGWQPGVMARFQESVDLLVKAGAEVVEVSCPTFVHALATYYLILPAE
ASSNLAKFDAMRYGLRVWPEGRPDASAEEVMRATRDAGFGPEVKRRIILGTYALSSGYYDAYYGQAQKVRTLISRDFDAA
FAKADVLVSPTAPTTAFKLGEKLDDPLAMYLNDLATIPANLAGVPGISVPSGLADEDGLPAGFQILAPALADDRCYRVGA
ALEALLHDQWGGPLLDKAPALEGARP

Sequences:

>Translated_506_residues
MSIIRRTAAEIADALAAGETTSAEVTRTHLDRIAAVDGAVHAFLHVDAEGALAQAAESDARRAAGTPLSPLDGVPIAVKD
VLATEGLPTTCGSKILEGWIPPYDATAVARLRAAGLPILGKTNMDEFAMGSSTEHSAYGPTHNPWDLDRIPGGSGGGSAA
AVAAFEAPLALGTDTGGSIRQPGAVTGTVGVKPTYGGVSRYGLVALANSLDQVGPVTRTVLDSALLHEVIGGHDPRDSTS
IDQPLPSLVEAARLGATGDLSGLRVGVITELAGDGWQPGVMARFQESVDLLVKAGAEVVEVSCPTFVHALATYYLILPAE
ASSNLAKFDAMRYGLRVWPEGRPDASAEEVMRATRDAGFGPEVKRRIILGTYALSSGYYDAYYGQAQKVRTLISRDFDAA
FAKADVLVSPTAPTTAFKLGEKLDDPLAMYLNDLATIPANLAGVPGISVPSGLADEDGLPAGFQILAPALADDRCYRVGA
ALEALLHDQWGGPLLDKAPALEGARP
>Mature_505_residues
SIIRRTAAEIADALAAGETTSAEVTRTHLDRIAAVDGAVHAFLHVDAEGALAQAAESDARRAAGTPLSPLDGVPIAVKDV
LATEGLPTTCGSKILEGWIPPYDATAVARLRAAGLPILGKTNMDEFAMGSSTEHSAYGPTHNPWDLDRIPGGSGGGSAAA
VAAFEAPLALGTDTGGSIRQPGAVTGTVGVKPTYGGVSRYGLVALANSLDQVGPVTRTVLDSALLHEVIGGHDPRDSTSI
DQPLPSLVEAARLGATGDLSGLRVGVITELAGDGWQPGVMARFQESVDLLVKAGAEVVEVSCPTFVHALATYYLILPAEA
SSNLAKFDAMRYGLRVWPEGRPDASAEEVMRATRDAGFGPEVKRRIILGTYALSSGYYDAYYGQAQKVRTLISRDFDAAF
AKADVLVSPTAPTTAFKLGEKLDDPLAMYLNDLATIPANLAGVPGISVPSGLADEDGLPAGFQILAPALADDRCYRVGAA
LEALLHDQWGGPLLDKAPALEGARP

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: COG0154

COG function: function code J; Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=501, Percent_Identity=39.1217564870259, Blast_Score=311, Evalue=9e-85,
Organism=Homo sapiens, GI195972892, Length=512, Percent_Identity=24.4140625, Blast_Score=115, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17543272, Length=443, Percent_Identity=39.5033860045147, Blast_Score=265, Evalue=6e-71,
Organism=Caenorhabditis elegans, GI17537465, Length=496, Percent_Identity=25.4032258064516, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17538252, Length=192, Percent_Identity=33.8541666666667, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17556264, Length=299, Percent_Identity=27.7591973244147, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71990152, Length=258, Percent_Identity=29.0697674418605, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538254, Length=222, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323950, Length=416, Percent_Identity=36.0576923076923, Blast_Score=232, Evalue=9e-62,
Organism=Saccharomyces cerevisiae, GI6319685, Length=417, Percent_Identity=30.4556354916067, Blast_Score=107, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6320448, Length=229, Percent_Identity=31.4410480349345, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24648113, Length=461, Percent_Identity=39.9132321041215, Blast_Score=290, Evalue=2e-78,
Organism=Drosophila melanogaster, GI24652985, Length=506, Percent_Identity=25.098814229249, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI19922090, Length=506, Percent_Identity=25.098814229249, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24652981, Length=506, Percent_Identity=25.098814229249, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24652983, Length=506, Percent_Identity=25.098814229249, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24644968, Length=259, Percent_Identity=30.8880308880309, Blast_Score=112, Evalue=6e-25,
Organism=Drosophila melanogaster, GI161078093, Length=514, Percent_Identity=27.2373540856031, Blast_Score=109, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24648435, Length=251, Percent_Identity=31.0756972111554, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24648437, Length=251, Percent_Identity=31.0756972111554, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45550774, Length=251, Percent_Identity=31.0756972111554, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21356731, Length=512, Percent_Identity=26.5625, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24648441, Length=184, Percent_Identity=33.695652173913, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24648439, Length=184, Percent_Identity=33.695652173913, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: 6.3.5.-

Molecular weight: Translated: 52435; Mature: 52303

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00571 AMIDASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIIRRTAAEIADALAAGETTSAEVTRTHLDRIAAVDGAVHAFLHVDAEGALAQAAESDA
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHH
RRAAGTPLSPLDGVPIAVKDVLATEGLPTTCGSKILEGWIPPYDATAVARLRAAGLPILG
HHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEC
KTNMDEFAMGSSTEHSAYGPTHNPWDLDRIPGGSGGGSAAAVAAFEAPLALGTDTGGSIR
CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEECCCCCCCCC
QPGAVTGTVGVKPTYGGVSRYGLVALANSLDQVGPVTRTVLDSALLHEVIGGHDPRDSTS
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IDQPLPSLVEAARLGATGDLSGLRVGVITELAGDGWQPGVMARFQESVDLLVKAGAEVVE
CCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
VSCPTFVHALATYYLILPAEASSNLAKFDAMRYGLRVWPEGRPDASAEEVMRATRDAGFG
ECCHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHCCCCC
PEVKRRIILGTYALSSGYYDAYYGQAQKVRTLISRDFDAAFAKADVLVSPTAPTTAFKLG
HHHHHEEEEEEEHHCCCCCHHHHCHHHHHHHHHHCCHHHHHHHCCEEECCCCCHHHHHHH
EKLDDPLAMYLNDLATIPANLAGVPGISVPSGLADEDGLPAGFQILAPALADDRCYRVGA
HHCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
ALEALLHDQWGGPLLDKAPALEGARP
HHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SIIRRTAAEIADALAAGETTSAEVTRTHLDRIAAVDGAVHAFLHVDAEGALAQAAESDA
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHH
RRAAGTPLSPLDGVPIAVKDVLATEGLPTTCGSKILEGWIPPYDATAVARLRAAGLPILG
HHHCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEC
KTNMDEFAMGSSTEHSAYGPTHNPWDLDRIPGGSGGGSAAAVAAFEAPLALGTDTGGSIR
CCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEECCCCCCCCC
QPGAVTGTVGVKPTYGGVSRYGLVALANSLDQVGPVTRTVLDSALLHEVIGGHDPRDSTS
CCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
IDQPLPSLVEAARLGATGDLSGLRVGVITELAGDGWQPGVMARFQESVDLLVKAGAEVVE
CCCCHHHHHHHHHCCCCCCCCCCEEHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCEEE
VSCPTFVHALATYYLILPAEASSNLAKFDAMRYGLRVWPEGRPDASAEEVMRATRDAGFG
ECCHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCEECCCCCCCCCHHHHHHHHHCCCCC
PEVKRRIILGTYALSSGYYDAYYGQAQKVRTLISRDFDAAFAKADVLVSPTAPTTAFKLG
HHHHHEEEEEEEHHCCCCCHHHHCHHHHHHHHHHCCHHHHHHHCCEEECCCCCHHHHHHH
EKLDDPLAMYLNDLATIPANLAGVPGISVPSGLADEDGLPAGFQILAPALADDRCYRVGA
HHCCCHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHH
ALEALLHDQWGGPLLDKAPALEGARP
HHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA