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The map label for this gene is bioA [H]

Identifier: 119717636

GI number: 119717636

Start: 3615434

End: 3616738

Strand: Reverse

Name: bioA [H]

Synonym: Noca_3414

Alternate gene names: 119717636

Gene position: 3616738-3615434 (Counterclockwise)

Preceding gene: 119717637

Following gene: 119717635

Centisome position: 72.54

GC content: 71.95

Gene sequence:

>1305_bases
GTGAGCACCGCCCTCGTCGCCGAACCGGCCGAGCGGACCACGCTCGCAGGGCTGCTGGCGTTCGACCGGGCGCACGTGTG
GCATCCGTACGCCTCGATGACGGACCCGACCCCGGTGCGGCTGGTGACCGGCGCCCACGGCGTACGCCTGACCATGGCCG
ACGGGTCCCAGGTCATCGACGGCATGTCTTCGTGGTGGTCGGCGATCCACGGGTACCGAGTCCCCGAGCTCGACGCCGCA
CTCGTGGCACAGTCGCAGCGCATGAGCCACGTGATGTTCGGCGGCCTCACCCACGCCCCCGCCATTCGGCTGGCCCAGCG
GCTGGTCGCGATCACCCCGGATGCGCTGCAGCACGTGTTCCTCGCTGACTCCGGGTCGGTGAGCGTGGAGGTCGCGATCA
AGATGGTGCTCCAGTACCAGCGCGGCGTCGGTCGGCCGGAGCGGACCCGGCTGCTGACTGTGCGTGGCGGCTACCACGGC
GACACCTTCGGGTGCATGAGCGTGTGCGATCCGATCGGCGGGATGCACGCCATGTTCGCCGCCGTCCACCACTCCCAGGT
GTTCGCCGACCGGCCCCCCGGCCCGGGCGGCGACGTGGACGGGTGGGCCGACGGTGTCCGCCGCCTGGCCGCCACCCACG
CCCGCGAGTTGGCCGGCATCATCATCGAGCCCCTACTCCAGGGCGCCGGCGGCATGCACGTCTACGACGCCGCCTGCCTG
CGCATCCTGCGCGAGATCGCGGACGAGCACGACCTGGTGCTGGTCTTCGACGAGATCGCCACCGGCTTCGGCCGCACCGG
CCACCTGTTCGTCAGCGACCACGTCACCCCGGACATCTTGTGCCTGGGCAAGGCACTGACCGGCGGCTACCTCACCCTCG
CAGCGGTCCTCGCCACCGCCGAGATCGCCCACGGCATCTCCGGCAGCGAGTCTGGGGTGCTGATGCACGGCCCCACCTTC
ATGGGCAACCCGCTGGCCTGCGCGGTCGCCCTGGCGAGCCTGGACCTGCTCCAGACCCGCGACTGGGGCGCCGACGTACG
GCGTCTCCACGCCGCCCTGACCACCGGGCTCGAGCCGCTGCGTGCCGCCCCCGGCATTGCCGATGTTCGGGTCCTCGGGG
CGGTCGGCGTCGTCCAGCTCGACCACGAAGTCGACGTCGCCAAAGCCACCGACGCCGCCCTCGCCGAGGGGGTCTGGCTG
CGCCCGTTCCGCGACCTGGTCTACACAATGCCGCCCTACCCCACCCAACAGGCTGACGCCGCCCACATATGCGCCGCCAT
CGCCCACGCCGCCGCGGTCGCCTGA

Upstream 100 bases:

>100_bases
AGACAGCCCACGACATTGCCGGCGGCACCTCCGTTGCGGGGTCCGCCCCGGATCCGGCGATCCGCCGCCGTGGCGCCGGA
ACCGACGTGCCGGCCAACGC

Downstream 100 bases:

>100_bases
TGAGCGAACCCACCTGGGACGAATGTTCCGCCGGCCGACCCGTTGTCAGCGCCGGCGCCGTGCCGACCGGTGACCTACAG
CCCCGAGGACCCCACGACCG

Product: adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MSTALVAEPAERTTLAGLLAFDRAHVWHPYASMTDPTPVRLVTGAHGVRLTMADGSQVIDGMSSWWSAIHGYRVPELDAA
LVAQSQRMSHVMFGGLTHAPAIRLAQRLVAITPDALQHVFLADSGSVSVEVAIKMVLQYQRGVGRPERTRLLTVRGGYHG
DTFGCMSVCDPIGGMHAMFAAVHHSQVFADRPPGPGGDVDGWADGVRRLAATHARELAGIIIEPLLQGAGGMHVYDAACL
RILREIADEHDLVLVFDEIATGFGRTGHLFVSDHVTPDILCLGKALTGGYLTLAAVLATAEIAHGISGSESGVLMHGPTF
MGNPLACAVALASLDLLQTRDWGADVRRLHAALTTGLEPLRAAPGIADVRVLGAVGVVQLDHEVDVAKATDAALAEGVWL
RPFRDLVYTMPPYPTQQADAAHICAAIAHAAAVA

Sequences:

>Translated_434_residues
MSTALVAEPAERTTLAGLLAFDRAHVWHPYASMTDPTPVRLVTGAHGVRLTMADGSQVIDGMSSWWSAIHGYRVPELDAA
LVAQSQRMSHVMFGGLTHAPAIRLAQRLVAITPDALQHVFLADSGSVSVEVAIKMVLQYQRGVGRPERTRLLTVRGGYHG
DTFGCMSVCDPIGGMHAMFAAVHHSQVFADRPPGPGGDVDGWADGVRRLAATHARELAGIIIEPLLQGAGGMHVYDAACL
RILREIADEHDLVLVFDEIATGFGRTGHLFVSDHVTPDILCLGKALTGGYLTLAAVLATAEIAHGISGSESGVLMHGPTF
MGNPLACAVALASLDLLQTRDWGADVRRLHAALTTGLEPLRAAPGIADVRVLGAVGVVQLDHEVDVAKATDAALAEGVWL
RPFRDLVYTMPPYPTQQADAAHICAAIAHAAAVA
>Mature_433_residues
STALVAEPAERTTLAGLLAFDRAHVWHPYASMTDPTPVRLVTGAHGVRLTMADGSQVIDGMSSWWSAIHGYRVPELDAAL
VAQSQRMSHVMFGGLTHAPAIRLAQRLVAITPDALQHVFLADSGSVSVEVAIKMVLQYQRGVGRPERTRLLTVRGGYHGD
TFGCMSVCDPIGGMHAMFAAVHHSQVFADRPPGPGGDVDGWADGVRRLAATHARELAGIIIEPLLQGAGGMHVYDAACLR
ILREIADEHDLVLVFDEIATGFGRTGHLFVSDHVTPDILCLGKALTGGYLTLAAVLATAEIAHGISGSESGVLMHGPTFM
GNPLACAVALASLDLLQTRDWGADVRRLHAALTTGLEPLRAAPGIADVRVLGAVGVVQLDHEVDVAKATDAALAEGVWLR
PFRDLVYTMPPYPTQQADAAHICAAIAHAAAVA

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=351, Percent_Identity=27.9202279202279, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4557809, Length=343, Percent_Identity=28.2798833819242, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI284507298, Length=171, Percent_Identity=35.672514619883, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI37574042, Length=417, Percent_Identity=24.4604316546763, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI226442709, Length=357, Percent_Identity=25.7703081232493, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI226442705, Length=357, Percent_Identity=25.7703081232493, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI24119277, Length=420, Percent_Identity=25, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1786991, Length=419, Percent_Identity=53.2219570405728, Blast_Score=425, Evalue=1e-120,
Organism=Escherichia coli, GI145693181, Length=349, Percent_Identity=30.0859598853868, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1788044, Length=341, Percent_Identity=32.5513196480938, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789759, Length=297, Percent_Identity=32.996632996633, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1789016, Length=362, Percent_Identity=29.5580110497238, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1787560, Length=374, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI25144271, Length=130, Percent_Identity=36.9230769230769, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25144274, Length=132, Percent_Identity=36.3636363636364, Blast_Score=92, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324386, Length=443, Percent_Identity=40.6320541760722, Blast_Score=342, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6323470, Length=415, Percent_Identity=26.7469879518072, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324432, Length=349, Percent_Identity=24.3553008595989, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357415, Length=399, Percent_Identity=25.5639097744361, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28574759, Length=358, Percent_Identity=26.2569832402235, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI161085790, Length=357, Percent_Identity=26.0504201680672, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356575, Length=350, Percent_Identity=22.5714285714286, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 45857; Mature: 45726

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTALVAEPAERTTLAGLLAFDRAHVWHPYASMTDPTPVRLVTGAHGVRLTMADGSQVID
CCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEECCCHHHHH
GMSSWWSAIHGYRVPELDAALVAQSQRMSHVMFGGLTHAPAIRLAQRLVAITPDALQHVF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHEE
LADSGSVSVEVAIKMVLQYQRGVGRPERTRLLTVRGGYHGDTFGCMSVCDPIGGMHAMFA
EECCCCEEHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCHHHHHHH
AVHHSQVFADRPPGPGGDVDGWADGVRRLAATHARELAGIIIEPLLQGAGGMHVYDAACL
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
RILREIADEHDLVLVFDEIATGFGRTGHLFVSDHVTPDILCLGKALTGGYLTLAAVLATA
HHHHHHCCCCCEEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHH
EIAHGISGSESGVLMHGPTFMGNPLACAVALASLDLLQTRDWGADVRRLHAALTTGLEPL
HHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHH
RAAPGIADVRVLGAVGVVQLDHEVDVAKATDAALAEGVWLRPFRDLVYTMPPYPTQQADA
HCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHH
AHICAAIAHAAAVA
HHHHHHHHHHHHCC
>Mature Secondary Structure 
STALVAEPAERTTLAGLLAFDRAHVWHPYASMTDPTPVRLVTGAHGVRLTMADGSQVID
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCEEEEECCCHHHHH
GMSSWWSAIHGYRVPELDAALVAQSQRMSHVMFGGLTHAPAIRLAQRLVAITPDALQHVF
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHEE
LADSGSVSVEVAIKMVLQYQRGVGRPERTRLLTVRGGYHGDTFGCMSVCDPIGGMHAMFA
EECCCCEEHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHCCCCHHHHHHH
AVHHSQVFADRPPGPGGDVDGWADGVRRLAATHARELAGIIIEPLLQGAGGMHVYDAACL
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
RILREIADEHDLVLVFDEIATGFGRTGHLFVSDHVTPDILCLGKALTGGYLTLAAVLATA
HHHHHHCCCCCEEEEEHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHH
EIAHGISGSESGVLMHGPTFMGNPLACAVALASLDLLQTRDWGADVRRLHAALTTGLEPL
HHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHH
RAAPGIADVRVLGAVGVVQLDHEVDVAKATDAALAEGVWLRPFRDLVYTMPPYPTQQADA
HCCCCHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCHH
AHICAAIAHAAAVA
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8890743 [H]