Click here to switch to the map view.

The map label for this gene is rnc [H]

Identifier: 119717505

GI number: 119717505

Start: 3488533

End: 3489363

Strand: Reverse

Name: rnc [H]

Synonym: Noca_3281

Alternate gene names: 119717505

Gene position: 3489363-3488533 (Counterclockwise)

Preceding gene: 119717506

Following gene: 119717504

Centisome position: 69.99

GC content: 72.2

Gene sequence:

>831_bases
GTGCCAAGCACCTGCCGCACCGCGCGTGCGGCCAGTGCGGCCAGTACGGCGCGCGCGCCGACCGTCGTCAGGTCCTCTGA
TCCGACCGGTCCGCTGACCAACTACGCAGAGCTCCGAGCGGCACTCGGGGATCCCACGCTGGACCCCGAGCTGCTCGAGC
GCGCCCTCACGCACCGTTCGTTCGCCTACGAGAACGGCGGGTTGCCCACCAACGAGCGACTGGAGTTCCTCGGGGACTCC
GTGCTCGGCGTGGTGGTCACCGAGACGCTCTACCTCAAGCACCCGGACCTCTCCGAGGGCCGGCTGGCCAAGCTGCGCGC
CGCAGTCGTCAACGCCCGCGCGCTGGCCGAGGTCGGCCGCCGGATCGGGGTGGGCGAGCACGTCAAGCTCGGGCGCGGCG
AGGAGTCGACGGGTGGCCGCCACAAGGCCTCGATCCTCTCCGACACCGTCGAGGCCGTGATCGGCGCTGTGCACCTCAGC
GGCGGCTTCACCACCTCCGCGGTCGTGGTGCACCGCCTGTTCGACCCGCTGATCGAGGCCGCGTCCGCGCTCGGGGCGGG
CCTCGACTGGAAGACCTCCCTGCAGGAGCTGTCCGCCGAGCACGGCCTCGGCGTCCCCGAGTACGTCATCGAGGACGACG
GCCCCGACCACATGAAGACGTTCACCGCCCAGGTCCGCGTGGGCGAGGGCCTGTACGGCAACGGCGTGGGCCGCTCCAAG
AAGGAGGCCGAGCAGGCCGCCGCGGAGACGGCGTACGGCGAGATCGCCTCCGACCTCGGCGTCGACGACCCAGCCGTGGA
CGCGGCCGCCCACTCCGCCCACAAGAGCTGA

Upstream 100 bases:

>100_bases
GTCCCGAAGCGGAAGATGTCGCGCAGCAACACGCGTCACCGTCGTTCGGCCTGGAAGGCCGTCGCCCCGACCCTGGTGAC
CTGCGCGAACCCCGCCTGCG

Downstream 100 bases:

>100_bases
CCCGAGGCACGACTTGCCGGAGCTGCCCGAGGTCGAAGTGGTGCGCGCCGGCCTCGAGCGGCACGTGCTCGGCGCCACGA
TCGCCCGCGTCGACGTGCTG

Product: ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III [H]

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MPSTCRTARAASAASTARAPTVVRSSDPTGPLTNYAELRAALGDPTLDPELLERALTHRSFAYENGGLPTNERLEFLGDS
VLGVVVTETLYLKHPDLSEGRLAKLRAAVVNARALAEVGRRIGVGEHVKLGRGEESTGGRHKASILSDTVEAVIGAVHLS
GGFTTSAVVVHRLFDPLIEAASALGAGLDWKTSLQELSAEHGLGVPEYVIEDDGPDHMKTFTAQVRVGEGLYGNGVGRSK
KEAEQAAAETAYGEIASDLGVDDPAVDAAAHSAHKS

Sequences:

>Translated_276_residues
MPSTCRTARAASAASTARAPTVVRSSDPTGPLTNYAELRAALGDPTLDPELLERALTHRSFAYENGGLPTNERLEFLGDS
VLGVVVTETLYLKHPDLSEGRLAKLRAAVVNARALAEVGRRIGVGEHVKLGRGEESTGGRHKASILSDTVEAVIGAVHLS
GGFTTSAVVVHRLFDPLIEAASALGAGLDWKTSLQELSAEHGLGVPEYVIEDDGPDHMKTFTAQVRVGEGLYGNGVGRSK
KEAEQAAAETAYGEIASDLGVDDPAVDAAAHSAHKS
>Mature_275_residues
PSTCRTARAASAASTARAPTVVRSSDPTGPLTNYAELRAALGDPTLDPELLERALTHRSFAYENGGLPTNERLEFLGDSV
LGVVVTETLYLKHPDLSEGRLAKLRAAVVNARALAEVGRRIGVGEHVKLGRGEESTGGRHKASILSDTVEAVIGAVHLSG
GFTTSAVVVHRLFDPLIEAASALGAGLDWKTSLQELSAEHGLGVPEYVIEDDGPDHMKTFTAQVRVGEGLYGNGVGRSKK
EAEQAAAETAYGEIASDLGVDDPAVDAAAHSAHKS

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs [H]

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain [H]

Homologues:

Organism=Homo sapiens, GI155030236, Length=242, Percent_Identity=30.1652892561983, Blast_Score=88, Evalue=8e-18,
Organism=Homo sapiens, GI155030234, Length=242, Percent_Identity=30.1652892561983, Blast_Score=88, Evalue=9e-18,
Organism=Escherichia coli, GI1788920, Length=207, Percent_Identity=37.6811594202899, Blast_Score=118, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6323895, Length=196, Percent_Identity=30.6122448979592, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17137682, Length=208, Percent_Identity=29.8076923076923, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907 [H]

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3 [H]

EC number: =3.1.26.3 [H]

Molecular weight: Translated: 28866; Mature: 28735

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50137 DS_RBD ; PS00517 RNASE_3_1 ; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSTCRTARAASAASTARAPTVVRSSDPTGPLTNYAELRAALGDPTLDPELLERALTHRS
CCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FAYENGGLPTNERLEFLGDSVLGVVVTETLYLKHPDLSEGRLAKLRAAVVNARALAEVGR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RIGVGEHVKLGRGEESTGGRHKASILSDTVEAVIGAVHLSGGFTTSAVVVHRLFDPLIEA
HCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ASALGAGLDWKTSLQELSAEHGLGVPEYVIEDDGPDHMKTFTAQVRVGEGLYGNGVGRSK
HHHHCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHEEECCCCCCCCCCCCH
KEAEQAAAETAYGEIASDLGVDDPAVDAAAHSAHKS
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
PSTCRTARAASAASTARAPTVVRSSDPTGPLTNYAELRAALGDPTLDPELLERALTHRS
CCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHH
FAYENGGLPTNERLEFLGDSVLGVVVTETLYLKHPDLSEGRLAKLRAAVVNARALAEVGR
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RIGVGEHVKLGRGEESTGGRHKASILSDTVEAVIGAVHLSGGFTTSAVVVHRLFDPLIEA
HCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
ASALGAGLDWKTSLQELSAEHGLGVPEYVIEDDGPDHMKTFTAQVRVGEGLYGNGVGRSK
HHHHCCCCCHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHEEECCCCCCCCCCCCH
KEAEQAAAETAYGEIASDLGVDDPAVDAAAHSAHKS
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA