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The map label for this gene is phoP [H]

Identifier: 119717052

GI number: 119717052

Start: 2997650

End: 2998345

Strand: Reverse

Name: phoP [H]

Synonym: Noca_2828

Alternate gene names: 119717052

Gene position: 2998345-2997650 (Counterclockwise)

Preceding gene: 119717054

Following gene: 119717050

Centisome position: 60.14

GC content: 73.42

Gene sequence:

>696_bases
ATGGGCCGGGCGGTCGTGGTCGAGGACGACGAGGACCTGCGCGACCTGGTCGAGCACGTGCTCCGCAGCGTCGGCCTGGA
GACCGCGGGCGCCGAGACCGGTGGGGAGGGCGTCCGGCTGACGCGCGAGCTGACGCCGGAGCTGATCACGTTGGACGTGC
AGCTGCCCGACATGCTCGGCACCGAGGTGTGCCGCCAGGTGCGCGAGTTCAGCGACGCCTACGTGATGATGATCACCAGC
CGCACCGAGGAGGTCGACCGCCTGCTGGCCCTCGACCTCGGCGCCGACGACTACCTGTCCAAGCCGTTCTCGCCCAAGGA
GCTCGCGGCCCGGGTCTCCGCGCTGCTGCGCCGACCGCGGTTCGCGCCGCCCCCGGAGGAGCCCGAGGAGGTCGTGCTGG
AGGCAGGGGGAGGGCTGACCCTCGTGCCGGTCCGGCACGTGGCGATGCTCGACGGCAAGCCGGTGCCGCTGACCCCCACC
GAGGTGGACCTGCTCGCCGCGCTCGCCGAGGAGCCCGGGAAGCCGCGCGACCGCGCCTCCCTCGTGGGCGCGATCTGGGG
CGGCGACTTCATCGAGTCCGACTTCCTCATCGACGTGCACGTCGCGAGCCTGCGCCGCAAGCTCCGCAAGGCCGGGTCGG
GCGGGGACTGGATCCGCACCGTGGCCGGCTCCGCGTACGCCCTGACCCCCCAGTAG

Upstream 100 bases:

>100_bases
GGCTGCGCCCGGGGCGTCGTCGCCTCGCCGACGCCGCGGTTGGGGCAAGATGTGCTCGGGCAGAGGGCGCCCGTGGTGCA
CCCTCGGGAAGGAGCCGCGG

Downstream 100 bases:

>100_bases
CGCTCAGGTGTCGGGCCGGTGCCGGGCCACCGTGAGGCCGACCAGTCGGGCGACCACGAGCGCGACGTAGAGCACGCCGG
CGGGACCGGAGGCTCATAGG

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MGRAVVVEDDEDLRDLVEHVLRSVGLETAGAETGGEGVRLTRELTPELITLDVQLPDMLGTEVCRQVREFSDAYVMMITS
RTEEVDRLLALDLGADDYLSKPFSPKELAARVSALLRRPRFAPPPEEPEEVVLEAGGGLTLVPVRHVAMLDGKPVPLTPT
EVDLLAALAEEPGKPRDRASLVGAIWGGDFIESDFLIDVHVASLRRKLRKAGSGGDWIRTVAGSAYALTPQ

Sequences:

>Translated_231_residues
MGRAVVVEDDEDLRDLVEHVLRSVGLETAGAETGGEGVRLTRELTPELITLDVQLPDMLGTEVCRQVREFSDAYVMMITS
RTEEVDRLLALDLGADDYLSKPFSPKELAARVSALLRRPRFAPPPEEPEEVVLEAGGGLTLVPVRHVAMLDGKPVPLTPT
EVDLLAALAEEPGKPRDRASLVGAIWGGDFIESDFLIDVHVASLRRKLRKAGSGGDWIRTVAGSAYALTPQ
>Mature_230_residues
GRAVVVEDDEDLRDLVEHVLRSVGLETAGAETGGEGVRLTRELTPELITLDVQLPDMLGTEVCRQVREFSDAYVMMITSR
TEEVDRLLALDLGADDYLSKPFSPKELAARVSALLRRPRFAPPPEEPEEVVLEAGGGLTLVPVRHVAMLDGKPVPLTPTE
VDLLAALAEEPGKPRDRASLVGAIWGGDFIESDFLIDVHVASLRRKLRKAGSGGDWIRTVAGSAYALTPQ

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=37.5, Blast_Score=143, Evalue=8e-36,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.5217391304348, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=36.4444444444444, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=33.6244541484716, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=34.7826086956522, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786911, Length=210, Percent_Identity=34.2857142857143, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=29.0748898678414, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=33.0396475770925, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=30.5309734513274, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1790552, Length=185, Percent_Identity=37.2972972972973, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI87082012, Length=206, Percent_Identity=31.5533980582524, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=27.9661016949153, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=30.3030303030303, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=27.3913043478261, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25073; Mature: 24942

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRAVVVEDDEDLRDLVEHVLRSVGLETAGAETGGEGVRLTRELTPELITLDVQLPDMLG
CCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHCCCEEEEEEEECCHHHH
TEVCRQVREFSDAYVMMITSRTEEVDRLLALDLGADDYLSKPFSPKELAARVSALLRRPR
HHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHCCC
FAPPPEEPEEVVLEAGGGLTLVPVRHVAMLDGKPVPLTPTEVDLLAALAEEPGKPRDRAS
CCCCCCCHHHHHEECCCCEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
LVGAIWGGDFIESDFLIDVHVASLRRKLRKAGSGGDWIRTVAGSAYALTPQ
HHHHHHCCCHHCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCC
>Mature Secondary Structure 
GRAVVVEDDEDLRDLVEHVLRSVGLETAGAETGGEGVRLTRELTPELITLDVQLPDMLG
CCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHCCCEEEEEEEECCHHHH
TEVCRQVREFSDAYVMMITSRTEEVDRLLALDLGADDYLSKPFSPKELAARVSALLRRPR
HHHHHHHHHHCCEEEEEEECCHHHHHHHHHHCCCCHHHHCCCCCHHHHHHHHHHHHHCCC
FAPPPEEPEEVVLEAGGGLTLVPVRHVAMLDGKPVPLTPTEVDLLAALAEEPGKPRDRAS
CCCCCCCHHHHHEECCCCEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHH
LVGAIWGGDFIESDFLIDVHVASLRRKLRKAGSGGDWIRTVAGSAYALTPQ
HHHHHHCCCHHCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]