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The map label for this gene is mhpD [H]

Identifier: 119717003

GI number: 119717003

Start: 2948586

End: 2949407

Strand: Reverse

Name: mhpD [H]

Synonym: Noca_2779

Alternate gene names: 119717003

Gene position: 2949407-2948586 (Counterclockwise)

Preceding gene: 119717006

Following gene: 119717002

Centisome position: 59.16

GC content: 73.6

Gene sequence:

>822_bases
GTGACCTCCCAGGACTCGAGAGCGGCCTCGATCACGGCCGCCGTCGACCGACTCTCCCAGGCCCAGGCCACCGGTGTCCC
GTGCGCGCCCGTCCGCGACCTGATCGGCACCGACGACCTGGCCGCGGCGTACGCCGTGCAGCAGGGTCTCGTGCAGGCCC
GGATCGCCGGGGGAGCCCGGGTCGTCGGCCGCAAGATCGGCGCGACGTCGGAGGCGGTGCAGACCCAGCTGGGCGTCGAC
CAGCCGGACTTCGGCTACCTGCTCGACGACATGGACGTCTCCCCCCGCGAGCGGCGCGACGGGCCGATCTCGATGCGCAC
GCTGCTCCAGCCCCGGGTGGAGGCCGAGGTCGCCTTCGTCCTCGCCCGCGACATCGACCCCGCCGAGGGCGCCGAGATCA
CCCTCGACCTGGTCCGAGACGCCGTCGAGGTCGCACTGCCGGCGCTCGAGATCGTCGACTCGCGGATCGCCGACTGGCGG
ATCGGGTTCACCGACACCGTCGCCGACAACGCCTCCAGCGGCCTGTTCGTGGTCGGCGCCGATGGCCACCCGCTGGACGA
GCTCGAGCCGCGGGATGTCGTCATGTCGCTGACGATCAACGGCGAGGAGCGCTCGTCGGGCACCGGCCTCGCCTGCCTGG
GCGACCCGCTCGAGGCGCTGCGCTGGCTGGCGGTGCAGGCGCACCGCTTCGGGGACCCGCTGCGCGCCGGCCACCTGATC
CTGTCCGGGGCGCTGGGCCCGTTCGTGCCGTTCGCCCCGGGCGACCGCGTCGTCGCGACCATCAGCGGCTTCGCGCCGCT
CAGCGTCACCTTCACCGAATGA

Upstream 100 bases:

>100_bases
CCGCCGGCGCCGACCACGACGACGTCGACGCGCGCCGGGAGACCGGCCGGCAGGGGGGGCGTCATGGCGAGAAACTGTAA
CAGGTTCTACTATCGGTCAC

Downstream 100 bases:

>100_bases
TCCGCGAGGAGTGAGCAGATGCCCAGATCGACCGCAGCCATCGTGGGGCCGGGCAACATCGGCACCGACCTGATGTACAA
GCTGCTGCGCGCCGCCGAGG

Product: hydratase/decarboxylase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTSQDSRAASITAAVDRLSQAQATGVPCAPVRDLIGTDDLAAAYAVQQGLVQARIAGGARVVGRKIGATSEAVQTQLGVD
QPDFGYLLDDMDVSPRERRDGPISMRTLLQPRVEAEVAFVLARDIDPAEGAEITLDLVRDAVEVALPALEIVDSRIADWR
IGFTDTVADNASSGLFVVGADGHPLDELEPRDVVMSLTINGEERSSGTGLACLGDPLEALRWLAVQAHRFGDPLRAGHLI
LSGALGPFVPFAPGDRVVATISGFAPLSVTFTE

Sequences:

>Translated_273_residues
MTSQDSRAASITAAVDRLSQAQATGVPCAPVRDLIGTDDLAAAYAVQQGLVQARIAGGARVVGRKIGATSEAVQTQLGVD
QPDFGYLLDDMDVSPRERRDGPISMRTLLQPRVEAEVAFVLARDIDPAEGAEITLDLVRDAVEVALPALEIVDSRIADWR
IGFTDTVADNASSGLFVVGADGHPLDELEPRDVVMSLTINGEERSSGTGLACLGDPLEALRWLAVQAHRFGDPLRAGHLI
LSGALGPFVPFAPGDRVVATISGFAPLSVTFTE
>Mature_272_residues
TSQDSRAASITAAVDRLSQAQATGVPCAPVRDLIGTDDLAAAYAVQQGLVQARIAGGARVVGRKIGATSEAVQTQLGVDQ
PDFGYLLDDMDVSPRERRDGPISMRTLLQPRVEAEVAFVLARDIDPAEGAEITLDLVRDAVEVALPALEIVDSRIADWRI
GFTDTVADNASSGLFVVGADGHPLDELEPRDVVMSLTINGEERSSGTGLACLGDPLEALRWLAVQAHRFGDPLRAGHLIL
SGALGPFVPFAPGDRVVATISGFAPLSVTFTE

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=255, Percent_Identity=50.1960784313725, Blast_Score=226, Evalue=1e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 28751; Mature: 28620

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQDSRAASITAAVDRLSQAQATGVPCAPVRDLIGTDDLAAAYAVQQGLVQARIAGGAR
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH
VVGRKIGATSEAVQTQLGVDQPDFGYLLDDMDVSPRERRDGPISMRTLLQPRVEAEVAFV
HHHHHCCCCHHHHHHHHCCCCCCCCEEECCCCCCCHHHCCCCCHHHHHHCCCHHHHEEEE
LARDIDPAEGAEITLDLVRDAVEVALPALEIVDSRIADWRIGFTDTVADNASSGLFVVGA
EECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHCCCCCCCEEEEEC
DGHPLDELEPRDVVMSLTINGEERSSGTGLACLGDPLEALRWLAVQAHRFGDPLRAGHLI
CCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHCCEE
LSGALGPFVPFAPGDRVVATISGFAPLSVTFTE
EECCCCCCCCCCCCCEEEEEEECCCEEEEEECC
>Mature Secondary Structure 
TSQDSRAASITAAVDRLSQAQATGVPCAPVRDLIGTDDLAAAYAVQQGLVQARIAGGAR
CCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHH
VVGRKIGATSEAVQTQLGVDQPDFGYLLDDMDVSPRERRDGPISMRTLLQPRVEAEVAFV
HHHHHCCCCHHHHHHHHCCCCCCCCEEECCCCCCCHHHCCCCCHHHHHHCCCHHHHEEEE
LARDIDPAEGAEITLDLVRDAVEVALPALEIVDSRIADWRIGFTDTVADNASSGLFVVGA
EECCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCEECCCCHHHCCCCCCCEEEEEC
DGHPLDELEPRDVVMSLTINGEERSSGTGLACLGDPLEALRWLAVQAHRFGDPLRAGHLI
CCCCCCCCCCCCEEEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCHHHCCEE
LSGALGPFVPFAPGDRVVATISGFAPLSVTFTE
EECCCCCCCCCCCCCEEEEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA