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The map label for this gene is insK [C]

Identifier: 119716978

GI number: 119716978

Start: 2924375

End: 2925136

Strand: Reverse

Name: insK [C]

Synonym: Noca_2753

Alternate gene names: 119716978

Gene position: 2925136-2924375 (Counterclockwise)

Preceding gene: 119716983

Following gene: 119716977

Centisome position: 58.67

GC content: 66.27

Gene sequence:

>762_bases
GTGCGCCGGATGACACCCGAGGGGCTCTACGGGCGTCGGAAGATGACCGCGCTGGTGCAGCGCACGTCGCCCGAGGCATC
GCCCGGCAGCGTGGACCGGGCGATGAGAACCCTGTCCCTGCAAGGGGTTCGGCGTTCGAAGGGGATCCGGACCACGATCC
CGGCCAAGGACGGCAAGCGAGCCGGTGACCTGCTGGATCGCGACTTCACCGCCGAAGCGCCGAACAGGACCTGGGTCATG
GACTTCACCTACGTGAGAACCTGGGCCGGGTTCGTCTACGTCGCGTTCATCCTCGACGTGTTCGCCCAGAAGATCGTCGC
CTGGAACGTCGCGCCCACCAAGGCCGTCGAGTTGGTCGACGTCCCGCTGCGAATGGCGTTGTGGCAACGCGACCGCGAGG
GCCACCCGATCGTGCCCGGCGAACTGATCGGCCACGCCGACGCCGGATCGCAATACACCTCGATCACCTTCACCGAACAC
CTCGCCGAGGAAGGCATCCGGCCCTCGATCGGGACGGTTGCCGATGCCTATGACAACGCCCTGATGGAGTGCGTGATCGG
GCTCTACAAGACCGAGTGCATCCGCACCACGGTCTTCCACGCCGGCCCCTACCGGACCATCGGCGACGTCGAGTACGCCA
CCGCCGGCTGGGTCGACTGGTACAACAACAGGCGCCTGCACGGCTCGCTTGGGATGATGACCCCAGTGGAGTTCGAGCAG
GCCCACTACGCGACTCTCAACCGAGAGCCGCAACCCGCATAG

Upstream 100 bases:

>100_bases
CTGGGCACAAGCCAACTGCCTTGTCGCAGCCCGGACGATCACCGACGCTCAGGTCACCAACCAGGTCCGTGACCTGGCCT
GGACCGTCGACCACGAAGGG

Downstream 100 bases:

>100_bases
GAGCGGCACAGAACCTGAGGCGCTTCAGTCTCCGGAACGGCAGAGGAGATCAAGCGCGCGCACGGGGCCGGCAAACCGGT
TCATGTCTGGTTCTCGAACG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MRRMTPEGLYGRRKMTALVQRTSPEASPGSVDRAMRTLSLQGVRRSKGIRTTIPAKDGKRAGDLLDRDFTAEAPNRTWVM
DFTYVRTWAGFVYVAFILDVFAQKIVAWNVAPTKAVELVDVPLRMALWQRDREGHPIVPGELIGHADAGSQYTSITFTEH
LAEEGIRPSIGTVADAYDNALMECVIGLYKTECIRTTVFHAGPYRTIGDVEYATAGWVDWYNNRRLHGSLGMMTPVEFEQ
AHYATLNREPQPA

Sequences:

>Translated_253_residues
MRRMTPEGLYGRRKMTALVQRTSPEASPGSVDRAMRTLSLQGVRRSKGIRTTIPAKDGKRAGDLLDRDFTAEAPNRTWVM
DFTYVRTWAGFVYVAFILDVFAQKIVAWNVAPTKAVELVDVPLRMALWQRDREGHPIVPGELIGHADAGSQYTSITFTEH
LAEEGIRPSIGTVADAYDNALMECVIGLYKTECIRTTVFHAGPYRTIGDVEYATAGWVDWYNNRRLHGSLGMMTPVEFEQ
AHYATLNREPQPA
>Mature_253_residues
MRRMTPEGLYGRRKMTALVQRTSPEASPGSVDRAMRTLSLQGVRRSKGIRTTIPAKDGKRAGDLLDRDFTAEAPNRTWVM
DFTYVRTWAGFVYVAFILDVFAQKIVAWNVAPTKAVELVDVPLRMALWQRDREGHPIVPGELIGHADAGSQYTSITFTEH
LAEEGIRPSIGTVADAYDNALMECVIGLYKTECIRTTVFHAGPYRTIGDVEYATAGWVDWYNNRRLHGSLGMMTPVEFEQ
AHYATLNREPQPA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=187, Percent_Identity=43.8502673796791, Blast_Score=150, Evalue=7e-37,
Organism=Escherichia coli, GI1789981, Length=239, Percent_Identity=28.4518828451883, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1788405, Length=231, Percent_Identity=29.8701298701299, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787263, Length=231, Percent_Identity=29.8701298701299, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786753, Length=231, Percent_Identity=29.8701298701299, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786570, Length=231, Percent_Identity=29.8701298701299, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786490, Length=231, Percent_Identity=29.8701298701299, Blast_Score=110, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 28395; Mature: 28395

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRMTPEGLYGRRKMTALVQRTSPEASPGSVDRAMRTLSLQGVRRSKGIRTTIPAKDGKR
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
AGDLLDRDFTAEAPNRTWVMDFTYVRTWAGFVYVAFILDVFAQKIVAWNVAPTKAVELVD
HHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VPLRMALWQRDREGHPIVPGELIGHADAGSQYTSITFTEHLAEEGIRPSIGTVADAYDNA
HHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHH
LMECVIGLYKTECIRTTVFHAGPYRTIGDVEYATAGWVDWYNNRRLHGSLGMMTPVEFEQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHCCCCEEECCCCCCCCCCHHH
AHYATLNREPQPA
HHHHHCCCCCCCC
>Mature Secondary Structure
MRRMTPEGLYGRRKMTALVQRTSPEASPGSVDRAMRTLSLQGVRRSKGIRTTIPAKDGKR
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCC
AGDLLDRDFTAEAPNRTWVMDFTYVRTWAGFVYVAFILDVFAQKIVAWNVAPTKAVELVD
HHHHHCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
VPLRMALWQRDREGHPIVPGELIGHADAGSQYTSITFTEHLAEEGIRPSIGTVADAYDNA
HHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHHHHHHHH
LMECVIGLYKTECIRTTVFHAGPYRTIGDVEYATAGWVDWYNNRRLHGSLGMMTPVEFEQ
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCHHHHCCCCEEECCCCCCCCCCHHH
AHYATLNREPQPA
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]