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The map label for this gene is yegH [C]

Identifier: 119716945

GI number: 119716945

Start: 2891726

End: 2893081

Strand: Reverse

Name: yegH [C]

Synonym: Noca_2720

Alternate gene names: 119716945

Gene position: 2893081-2891726 (Counterclockwise)

Preceding gene: 119716948

Following gene: 119716944

Centisome position: 58.03

GC content: 72.57

Gene sequence:

>1356_bases
ATGACCGCCTGGCTGCTGCTGGCGGCGGCGCTGCTCCTCATCGTCGCCTGCGGCGTGTTCGTCGCGGCCGAGTTCTCCTT
CGTCACCGTCGACCGCAGCCAGGTCGAGCGCGCCGCCGCGGCGGGGGACACCGGCGCGGGTGGCGTGCAGGCCGCGTTGC
GCACGCTGTCCACCCAGCTCTCCGGAGCCCAGGTCGGCATCACCATCACCAACCTCGCCATCGGCTACCTCGCCGAGCCG
GCGATCTCGGACCTGATCGACGGGCCCCTGCGCGGCCTCGGCACGCCGGAGCGTGCGATCACGCCGACGGCGATCGCGGT
CGGCCTGACGCTCGGCACGATCCTCACGATGATCTTCGGCGAGCTGGTGCCCAAGAACCTGGCGCTCGCCAAGCCGATGG
CCGTGGCCCGGGCGACCCAGCGCTTCCAACGCGGGTTCACGGCGCTGGCGCGCGGTCCCATCCGGGTGCTCAACGGCTCG
GCCAACGCCGTCGTACGCCGGCTCGGCATCGAGCCCCAGGAGGAGCTGCGCTCGGCGCGCAGCTCCACGGAGCTCGCCTC
GCTGATCCAGCGCTCGGCCGACCTCGGCACGCTCGACCTGGAGACCGCCGAGCTGATGGAGCGCTCGGTCGAGTTCGGCG
CCCGCACCGCGGGCGAGATCATGACGCCGCGGGTGCGCTCGAGCAGCCTGGAGGCGAACGACCGGGCCAACGTGGTCATC
GAGCTGACCCGGGAGACCGGGCACTCGCGGTTCCCGGTCCTGGACGCCGACGAGAACGTCGTCGGCACGGTGCACGTCAA
GAACGCCGTCGCCCTGCCCGTCTACGAGCGCGCGACCACGAAGGTCAAGCACCTGATGGCCAAGCCGATCGTGGTCCCCG
ACTCGCTGCGCCTCGACCCGCTGCTGGCGCTGCTGCGCGGGGACGGCTTCCAGCTCGCGGTCGTGATGGACGAGTACGGC
GGCTTCGCAGGCATCGTGACCCTGGAGGACGTCGTCGAGGAGATCGTCGGGGACATCGCCGACGAGCACGACCGGCTCAG
CGCCAACGCACGGCTGCAGCGGGACGGGACCTGGTCGCTCTCCGGCCTGCTGCGCCCCGACGAGGTCGAGGACATCACCG
GCGTCCTGCTGCCCGACCACGAGGACTACGACACGATCGCGGGGCTGGTCCTCCGGGTGCTCGGCCGGGTGCCCCGGGTC
GGCGACCTCGCGGAGGTGAGCGTCCCCGACCGCTCCGACCCCGACGAGCCGCGCGAGCAGCTCGCCGTCCTCACCGTGGA
GCGGATGGACGGGCTGCGGATCGACCGGCTGACGCTGCGGCTCCTCGACACCCCGATCGGGGGGGCGGAGTCGTGA

Upstream 100 bases:

>100_bases
ACGGCTCCCAAAGTCCCCGGCTCCCTCTGACCGGACTCAGCGCCGGAGCCAGGGGGAGCCGCCGCCCGCCTGACCCGGGC
CACGTCCGGGGAGCGTGCCG

Downstream 100 bases:

>100_bases
ACAGCCTGACCGCCATCGTGCTCGCCGTCTTCCTCCTGCTCGGCAACGCGTTCTTCGTGGGCGCGGAGTTCGCGTTGGTC
TCCGCGCGCCGCACGCAGCT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTAWLLLAAALLLIVACGVFVAAEFSFVTVDRSQVERAAAAGDTGAGGVQAALRTLSTQLSGAQVGITITNLAIGYLAEP
AISDLIDGPLRGLGTPERAITPTAIAVGLTLGTILTMIFGELVPKNLALAKPMAVARATQRFQRGFTALARGPIRVLNGS
ANAVVRRLGIEPQEELRSARSSTELASLIQRSADLGTLDLETAELMERSVEFGARTAGEIMTPRVRSSSLEANDRANVVI
ELTRETGHSRFPVLDADENVVGTVHVKNAVALPVYERATTKVKHLMAKPIVVPDSLRLDPLLALLRGDGFQLAVVMDEYG
GFAGIVTLEDVVEEIVGDIADEHDRLSANARLQRDGTWSLSGLLRPDEVEDITGVLLPDHEDYDTIAGLVLRVLGRVPRV
GDLAEVSVPDRSDPDEPREQLAVLTVERMDGLRIDRLTLRLLDTPIGGAES

Sequences:

>Translated_451_residues
MTAWLLLAAALLLIVACGVFVAAEFSFVTVDRSQVERAAAAGDTGAGGVQAALRTLSTQLSGAQVGITITNLAIGYLAEP
AISDLIDGPLRGLGTPERAITPTAIAVGLTLGTILTMIFGELVPKNLALAKPMAVARATQRFQRGFTALARGPIRVLNGS
ANAVVRRLGIEPQEELRSARSSTELASLIQRSADLGTLDLETAELMERSVEFGARTAGEIMTPRVRSSSLEANDRANVVI
ELTRETGHSRFPVLDADENVVGTVHVKNAVALPVYERATTKVKHLMAKPIVVPDSLRLDPLLALLRGDGFQLAVVMDEYG
GFAGIVTLEDVVEEIVGDIADEHDRLSANARLQRDGTWSLSGLLRPDEVEDITGVLLPDHEDYDTIAGLVLRVLGRVPRV
GDLAEVSVPDRSDPDEPREQLAVLTVERMDGLRIDRLTLRLLDTPIGGAES
>Mature_450_residues
TAWLLLAAALLLIVACGVFVAAEFSFVTVDRSQVERAAAAGDTGAGGVQAALRTLSTQLSGAQVGITITNLAIGYLAEPA
ISDLIDGPLRGLGTPERAITPTAIAVGLTLGTILTMIFGELVPKNLALAKPMAVARATQRFQRGFTALARGPIRVLNGSA
NAVVRRLGIEPQEELRSARSSTELASLIQRSADLGTLDLETAELMERSVEFGARTAGEIMTPRVRSSSLEANDRANVVIE
LTRETGHSRFPVLDADENVVGTVHVKNAVALPVYERATTKVKHLMAKPIVVPDSLRLDPLLALLRGDGFQLAVVMDEYGG
FAGIVTLEDVVEEIVGDIADEHDRLSANARLQRDGTWSLSGLLRPDEVEDITGVLLPDHEDYDTIAGLVLRVLGRVPRVG
DLAEVSVPDRSDPDEPREQLAVLTVERMDGLRIDRLTLRLLDTPIGGAES

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=379, Percent_Identity=29.287598944591, Blast_Score=171, Evalue=1e-42,
Organism=Escherichia coli, GI87082033, Length=322, Percent_Identity=28.5714285714286, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786879, Length=230, Percent_Identity=29.5652173913043, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1790664, Length=405, Percent_Identity=22.7160493827161, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI145693175, Length=386, Percent_Identity=22.7979274611399, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788119, Length=297, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48159; Mature: 48028

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAWLLLAAALLLIVACGVFVAAEFSFVTVDRSQVERAAAAGDTGAGGVQAALRTLSTQL
CHHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
SGAQVGITITNLAIGYLAEPAISDLIDGPLRGLGTPERAITPTAIAVGLTLGTILTMIFG
CCCEEEEEEHHHHHHHHCCHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELVPKNLALAKPMAVARATQRFQRGFTALARGPIRVLNGSANAVVRRLGIEPQEELRSAR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCHHHHHHHH
SSTELASLIQRSADLGTLDLETAELMERSVEFGARTAGEIMTPRVRSSSLEANDRANVVI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEE
ELTRETGHSRFPVLDADENVVGTVHVKNAVALPVYERATTKVKHLMAKPIVVPDSLRLDP
EEEECCCCCCCCEECCCCCEEEEEEECCEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHH
LLALLRGDGFQLAVVMDEYGGFAGIVTLEDVVEEIVGDIADEHDRLSANARLQRDGTWSL
HHHHHCCCCEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHCHHHHCCCCCEEECCCCCCC
SGLLRPDEVEDITGVLLPDHEDYDTIAGLVLRVLGRVPRVGDLAEVSVPDRSDPDEPREQ
CCCCCCCCHHHHCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
LAVLTVERMDGLRIDRLTLRLLDTPIGGAES
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TAWLLLAAALLLIVACGVFVAAEFSFVTVDRSQVERAAAAGDTGAGGVQAALRTLSTQL
HHHHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHCCCCCCHHHHHHHHHHHHHC
SGAQVGITITNLAIGYLAEPAISDLIDGPLRGLGTPERAITPTAIAVGLTLGTILTMIFG
CCCEEEEEEHHHHHHHHCCHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ELVPKNLALAKPMAVARATQRFQRGFTALARGPIRVLNGSANAVVRRLGIEPQEELRSAR
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHCCCCHHHHHHHH
SSTELASLIQRSADLGTLDLETAELMERSVEFGARTAGEIMTPRVRSSSLEANDRANVVI
HHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEE
ELTRETGHSRFPVLDADENVVGTVHVKNAVALPVYERATTKVKHLMAKPIVVPDSLRLDP
EEEECCCCCCCCEECCCCCEEEEEEECCEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHH
LLALLRGDGFQLAVVMDEYGGFAGIVTLEDVVEEIVGDIADEHDRLSANARLQRDGTWSL
HHHHHCCCCEEEEEEEECCCCEEEEEEHHHHHHHHHHHHHCHHHHCCCCCEEECCCCCCC
SGLLRPDEVEDITGVLLPDHEDYDTIAGLVLRVLGRVPRVGDLAEVSVPDRSDPDEPREQ
CCCCCCCCHHHHCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
LAVLTVERMDGLRIDRLTLRLLDTPIGGAES
HHHHHHHHHCCCCHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]