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The map label for this gene is argB

Identifier: 119716696

GI number: 119716696

Start: 2631082

End: 2632020

Strand: Direct

Name: argB

Synonym: Noca_2470

Alternate gene names: 119716696

Gene position: 2631082-2632020 (Clockwise)

Preceding gene: 119716695

Following gene: 119716697

Centisome position: 52.77

GC content: 71.25

Gene sequence:

>939_bases
ATGAGCATCGAGCACACGTCCCACGACCCGAGCAAGCCCGATCCGGCCAAGGCCCGCACGCTCGCGGCGGCACTGCCCTG
GCTGAAGCGCTACCACGGCAAGATCGTGGTCGTGAAGTACGGCGGCAACGCCATGACCGACGAGACGCTGAAGCGGGCCT
TCGCCGAGGACATCGCCTTCCTGCGGTTCGCCGGCTTCAAGCCCGTGGTCGTCCACGGCGGTGGCCCGCAGATCTCGACG
ATGCTGGATCGCCTCGGGATCAGGTCGGAGTTCCGCGGCGGCCTGCGGGTGACGACCCCGGAGGCCATGGACGTCGTCCG
GATGGTGCTGGTCGGCCAGGTGCAGCGTGAGCTCGTCGGGCTGATCAACGAGCACGGCCCGCTCGCCGTGGGCTGCTCGG
GCGAGGATGCCGGGCTGTTCACCGCCGAGCCGGCGAACACCGTCATCGACGGCGAGGAGGTCGACCTCGGCCTGGTCGGC
GAGGTCGCCCGGGTGCGGCCCGAGTCGGTGCTCGACTTGATCGAGGCCGGCCGGATCCCGGTCGTCTCCAGCGTCGCGCC
GGACGCGGACGGGCAGGTCCACAACGTGAACGCCGACTCCGCCGCCGCGGCCCTCGCCGTCGCGCTCGGCGCCGAGAAGC
TGCTGGTCCTCACCGACGTCGAGGGCCTCTACCTCGACTGGCCGAGCTCGGACGACGTGATCGGCGAGATCAGCCCGGAG
GCGCTGGAGGAGATCCTCCCCACCCTCGCCTCGGGGATGGTGCCGAAGATGGGCGCCTGCCTGCAGGCGGTCCGGAACGG
CGTCCCTCGGGCCACCGTCGTCGACGGCCGCGAGCCGCACGCGGTCCTGCTGGAGCTCTTCACCAACGAGGGCGTCGGCA
CCCAGGTGCTGCCCGGCGTCGAGACCAAGACCCGGAAGGCGAGGGACACCCAGTCATGA

Upstream 100 bases:

>100_bases
TCAGCGTCACCATCGACCTCAAGTCCGGCTCCGAGCGGGCGACGGTCTGGACCAACGACCTCACCCACGCCTACGTCCAC
GAGAACAGCGCGTACTCCTC

Downstream 100 bases:

>100_bases
CCGATTCCACCGAAGCCGTTTCTGGGGGGTCCAAGGAGGGCGGAGCCCCCCTTGTGGGCGGAGCCCCCCTTGCGGAGCGT
TACGCCGCCAGCCTGATGAA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSIEHTSHDPSKPDPAKARTLAAALPWLKRYHGKIVVVKYGGNAMTDETLKRAFAEDIAFLRFAGFKPVVVHGGGPQIST
MLDRLGIRSEFRGGLRVTTPEAMDVVRMVLVGQVQRELVGLINEHGPLAVGCSGEDAGLFTAEPANTVIDGEEVDLGLVG
EVARVRPESVLDLIEAGRIPVVSSVAPDADGQVHNVNADSAAAALAVALGAEKLLVLTDVEGLYLDWPSSDDVIGEISPE
ALEEILPTLASGMVPKMGACLQAVRNGVPRATVVDGREPHAVLLELFTNEGVGTQVLPGVETKTRKARDTQS

Sequences:

>Translated_312_residues
MSIEHTSHDPSKPDPAKARTLAAALPWLKRYHGKIVVVKYGGNAMTDETLKRAFAEDIAFLRFAGFKPVVVHGGGPQIST
MLDRLGIRSEFRGGLRVTTPEAMDVVRMVLVGQVQRELVGLINEHGPLAVGCSGEDAGLFTAEPANTVIDGEEVDLGLVG
EVARVRPESVLDLIEAGRIPVVSSVAPDADGQVHNVNADSAAAALAVALGAEKLLVLTDVEGLYLDWPSSDDVIGEISPE
ALEEILPTLASGMVPKMGACLQAVRNGVPRATVVDGREPHAVLLELFTNEGVGTQVLPGVETKTRKARDTQS
>Mature_311_residues
SIEHTSHDPSKPDPAKARTLAAALPWLKRYHGKIVVVKYGGNAMTDETLKRAFAEDIAFLRFAGFKPVVVHGGGPQISTM
LDRLGIRSEFRGGLRVTTPEAMDVVRMVLVGQVQRELVGLINEHGPLAVGCSGEDAGLFTAEPANTVIDGEEVDLGLVGE
VARVRPESVLDLIEAGRIPVVSSVAPDADGQVHNVNADSAAAALAVALGAEKLLVLTDVEGLYLDWPSSDDVIGEISPEA
LEEILPTLASGMVPKMGACLQAVRNGVPRATVVDGREPHAVLLELFTNEGVGTQVLPGVETKTRKARDTQS

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=294, Percent_Identity=26.8707482993197, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693208, Length=266, Percent_Identity=31.203007518797, Blast_Score=82, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320913, Length=280, Percent_Identity=30, Blast_Score=97, Evalue=4e-21,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_NOCSJ (A1SJI9)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_923661.1
- ProteinModelPortal:   A1SJI9
- SMR:   A1SJI9
- STRING:   A1SJI9
- GeneID:   4597092
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_2470
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   A1SJI9
- ProtClustDB:   PRK00942
- BioCyc:   NSP35761:NOCA_2470-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32999; Mature: 32868

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: BINDING 96-96 BINDING 195-195

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEHTSHDPSKPDPAKARTLAAALPWLKRYHGKIVVVKYGGNAMTDETLKRAFAEDIAF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHH
LRFAGFKPVVVHGGGPQISTMLDRLGIRSEFRGGLRVTTPEAMDVVRMVLVGQVQRELVG
HHHCCCCEEEEECCCCHHHHHHHHHCCHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHH
LINEHGPLAVGCSGEDAGLFTAEPANTVIDGEEVDLGLVGEVARVRPESVLDLIEAGRIP
HHCCCCCEEEECCCCCCCEEEECCCCCEECCCCCCCHHHHHHHHCCHHHHHHHHHCCCCC
VVSSVAPDADGQVHNVNADSAAAALAVALGAEKLLVLTDVEGLYLDWPSSDDVIGEISPE
EEECCCCCCCCCEEECCCHHHHHHHHHHHCCCEEEEEEECCEEEEECCCCCCCCCCCCHH
ALEEILPTLASGMVPKMGACLQAVRNGVPRATVVDGREPHAVLLELFTNEGVGTQVLPGV
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
ETKTRKARDTQS
CHHHHCCCCCCC
>Mature Secondary Structure 
SIEHTSHDPSKPDPAKARTLAAALPWLKRYHGKIVVVKYGGNAMTDETLKRAFAEDIAF
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHH
LRFAGFKPVVVHGGGPQISTMLDRLGIRSEFRGGLRVTTPEAMDVVRMVLVGQVQRELVG
HHHCCCCEEEEECCCCHHHHHHHHHCCHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHH
LINEHGPLAVGCSGEDAGLFTAEPANTVIDGEEVDLGLVGEVARVRPESVLDLIEAGRIP
HHCCCCCEEEECCCCCCCEEEECCCCCEECCCCCCCHHHHHHHHCCHHHHHHHHHCCCCC
VVSSVAPDADGQVHNVNADSAAAALAVALGAEKLLVLTDVEGLYLDWPSSDDVIGEISPE
EEECCCCCCCCCEEECCCHHHHHHHHHHHCCCEEEEEEECCEEEEECCCCCCCCCCCCHH
ALEEILPTLASGMVPKMGACLQAVRNGVPRATVVDGREPHAVLLELFTNEGVGTQVLPGV
HHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCC
ETKTRKARDTQS
CHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA