Click here to switch to the map view.

The map label for this gene is argC [H]

Identifier: 119716694

GI number: 119716694

Start: 2628891

End: 2629937

Strand: Direct

Name: argC [H]

Synonym: Noca_2468

Alternate gene names: 119716694

Gene position: 2628891-2629937 (Clockwise)

Preceding gene: 119716692

Following gene: 119716695

Centisome position: 52.73

GC content: 73.07

Gene sequence:

>1047_bases
ATGCACATGACCAGCATTCGGATCGCGGTCGCCGGCGCCAGCGGCTACGCGGGGGGCGAGCTGTTGCGCCTGCTCCTGGG
CCACCCGGACGTGGAGATCGGCGCCCTCACCGGCGCCTCGAACGCGGGCCAGCCCCTGGGCGCGTTGCAGCCGCACCTGG
TCCCGCTCGCCGACCGGGTCCTGGTGGAGACCTCCCTGGAGACGCTCTCCGGCCACGACGTGGTGTTCCTGGCACTCCCG
CACGGTCAGTCCGGTGAGCTCGCCGCGCGGCTCGGCGACGCGGACCCGGAGACCGTGGTCGTCGACTGCGGTGCCGACTT
CCGGCTCGCCGACGCCGCCGCGTGGGAGCGGTACTACGGCGGCCCGCACGCCGGCACCTGGCCCTACGGCCTCCCGGAGC
TCCCCGGTCAGCGGGAGCGGCTGTCCGGCGCCCGCCGGATCGCGGTGCCCGGCTGCTACCCGACGATCTCGACGCTCGCG
CTCGCGCCGGCGGTCGCGGCCGGCATCGTCGAACCCGACGTGGTCGTGGTCGCCGCCTCCGGCACCAGCGGCGCCGGCAA
GGCGGCCAAGCCCCACCTGCTCGGCAGCGAGATCATGGGCAACGCGAGCGCCTACGGCGTCGGCGGCGTCCACCGGCACA
CCCCTGAGATCACCCAGAACCTCTCCGCGCTGGTCCACGAGACCGTCAAGGTCAGCTTCACGCCGCTGCTCGTGCCGATG
CCCCGCGGCATCCTCGCCACCTGCTCGGCGCCCCTGCGCGGCGACGTCAGCGCCGAGGACGCCTACGCCGTCTACGCCAA
GGCGTACGCCGACGAGCCGTTCATCCACCTGCTCCCGGTCGGCCAGTGGCCGCAGACCAAGTCGGTGACCGGGTCCAACG
CCGTGCACCTCCAGGTCACGGTCGACGAGGACGCACGACGAATGGTCGCCGTCGGAGCCGTGGACAACCTGTCCAAGGGC
ACCGCCGGCGCTGCCGTCCAGTGCATGAACCTCGCGCTCGGTCTCGACGAAGGACTGGGCCTCTCGACCGTAGGAGTAGC
TCCGTGA

Upstream 100 bases:

>100_bases
TGATGGGAACCTAGACCGCGGCGCCGACGGCGCGCACCGGCGTTTCGGTGCCGGCCGGCGGAAGGCACTTGCACATGAAC
ATGCGGTTCACTGTATAGTC

Downstream 100 bases:

>100_bases
GTGTCACCTCCCCGAAGGGCTTCCGGGCCGCCGGCGTCGCCGCCGGCCTGAAGTCCACCGGCGCCAAGGACGTCGCCCTC
GTTGTCAACGACGGGCCGCA

Product: N-acetyl-gamma-glutamyl-phosphate reductase

Products: NA

Alternate protein names: AGPR; N-acetyl-glutamate semialdehyde dehydrogenase; NAGSA dehydrogenase [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MHMTSIRIAVAGASGYAGGELLRLLLGHPDVEIGALTGASNAGQPLGALQPHLVPLADRVLVETSLETLSGHDVVFLALP
HGQSGELAARLGDADPETVVVDCGADFRLADAAAWERYYGGPHAGTWPYGLPELPGQRERLSGARRIAVPGCYPTISTLA
LAPAVAAGIVEPDVVVVAASGTSGAGKAAKPHLLGSEIMGNASAYGVGGVHRHTPEITQNLSALVHETVKVSFTPLLVPM
PRGILATCSAPLRGDVSAEDAYAVYAKAYADEPFIHLLPVGQWPQTKSVTGSNAVHLQVTVDEDARRMVAVGAVDNLSKG
TAGAAVQCMNLALGLDEGLGLSTVGVAP

Sequences:

>Translated_348_residues
MHMTSIRIAVAGASGYAGGELLRLLLGHPDVEIGALTGASNAGQPLGALQPHLVPLADRVLVETSLETLSGHDVVFLALP
HGQSGELAARLGDADPETVVVDCGADFRLADAAAWERYYGGPHAGTWPYGLPELPGQRERLSGARRIAVPGCYPTISTLA
LAPAVAAGIVEPDVVVVAASGTSGAGKAAKPHLLGSEIMGNASAYGVGGVHRHTPEITQNLSALVHETVKVSFTPLLVPM
PRGILATCSAPLRGDVSAEDAYAVYAKAYADEPFIHLLPVGQWPQTKSVTGSNAVHLQVTVDEDARRMVAVGAVDNLSKG
TAGAAVQCMNLALGLDEGLGLSTVGVAP
>Mature_348_residues
MHMTSIRIAVAGASGYAGGELLRLLLGHPDVEIGALTGASNAGQPLGALQPHLVPLADRVLVETSLETLSGHDVVFLALP
HGQSGELAARLGDADPETVVVDCGADFRLADAAAWERYYGGPHAGTWPYGLPELPGQRERLSGARRIAVPGCYPTISTLA
LAPAVAAGIVEPDVVVVAASGTSGAGKAAKPHLLGSEIMGNASAYGVGGVHRHTPEITQNLSALVHETVKVSFTPLLVPM
PRGILATCSAPLRGDVSAEDAYAVYAKAYADEPFIHLLPVGQWPQTKSVTGSNAVHLQVTVDEDARRMVAVGAVDNLSKG
TAGAAVQCMNLALGLDEGLGLSTVGVAP

Specific function: Arginine biosynthesis; third step. [C]

COG id: COG0002

COG function: function code E; Acetylglutamate semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790396, Length=346, Percent_Identity=37.8612716763006, Blast_Score=158, Evalue=4e-40,
Organism=Saccharomyces cerevisiae, GI6320913, Length=338, Percent_Identity=27.810650887574, Blast_Score=109, Evalue=8e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023013
- InterPro:   IPR000706
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.38 [H]

Molecular weight: Translated: 35650; Mature: 35650

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMTSIRIAVAGASGYAGGELLRLLLGHPDVEIGALTGASNAGQPLGALQPHLVPLADRV
CCCEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHH
LVETSLETLSGHDVVFLALPHGQSGELAARLGDADPETVVVDCGADFRLADAAAWERYYG
HHHHHHHHCCCCCEEEEEECCCCCCCHHEECCCCCCCEEEEECCCCCEEHHHHHHHHHCC
GPHAGTWPYGLPELPGQRERLSGARRIAVPGCYPTISTLALAPAVAAGIVEPDVVVVAAS
CCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
GTSGAGKAAKPHLLGSEIMGNASAYGVGGVHRHTPEITQNLSALVHETVKVSFTPLLVPM
CCCCCCCCCCCCCCCHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEEEC
PRGILATCSAPLRGDVSAEDAYAVYAKAYADEPFIHLLPVGQWPQTKSVTGSNAVHLQVT
CCCEEEECCCCCCCCCCCCCCEEEEEEHHCCCCEEEEEECCCCCCCCCCCCCCEEEEEEE
VDEDARRMVAVGAVDNLSKGTAGAAVQCMNLALGLDEGLGLSTVGVAP
ECCCCCEEEEEECCCCCCCCCCCHHHEEHHHHEECCCCCCCCCCCCCC
>Mature Secondary Structure
MHMTSIRIAVAGASGYAGGELLRLLLGHPDVEIGALTGASNAGQPLGALQPHLVPLADRV
CCCEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHH
LVETSLETLSGHDVVFLALPHGQSGELAARLGDADPETVVVDCGADFRLADAAAWERYYG
HHHHHHHHCCCCCEEEEEECCCCCCCHHEECCCCCCCEEEEECCCCCEEHHHHHHHHHCC
GPHAGTWPYGLPELPGQRERLSGARRIAVPGCYPTISTLALAPAVAAGIVEPDVVVVAAS
CCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEC
GTSGAGKAAKPHLLGSEIMGNASAYGVGGVHRHTPEITQNLSALVHETVKVSFTPLLVPM
CCCCCCCCCCCCCCCHHHHCCCCEECCCCCCCCCHHHHHHHHHHHHHHHEEEEEEEEEEC
PRGILATCSAPLRGDVSAEDAYAVYAKAYADEPFIHLLPVGQWPQTKSVTGSNAVHLQVT
CCCEEEECCCCCCCCCCCCCCEEEEEEHHCCCCEEEEEECCCCCCCCCCCCCCEEEEEEE
VDEDARRMVAVGAVDNLSKGTAGAAVQCMNLALGLDEGLGLSTVGVAP
ECCCCCEEEEEECCCCCCCCCCCHHHEEHHHHEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]