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The map label for this gene is pheS [H]

Identifier: 119716691

GI number: 119716691

Start: 2624334

End: 2625440

Strand: Direct

Name: pheS [H]

Synonym: Noca_2465

Alternate gene names: 119716691

Gene position: 2624334-2625440 (Clockwise)

Preceding gene: 119716690

Following gene: 119716692

Centisome position: 52.64

GC content: 72.63

Gene sequence:

>1107_bases
TTGTCGGGCCCGAACACCGATTACGACCCCGTGGAGGTCACCCCGTTGCAGCCCGAGGAGGTCGAGGCCGCGCGCGACGC
GGCGCTCGCGGCCATCGCGGCGGCGGGCGATCTCACCGAGCTCAAGCAGGCGCGCCTGGAGCACGCCGGCGACCGCTCGC
CGCTCGCGCTCGCCAACCGGGAGATCGGGGCGTTGCCGCCCCAGGCCCGCAAGGAGGCCGGCCAGCGCATCGGCCAGGCC
CGCGGCGCCGTGAACCAGGCCCTCGCCGCCCGCCAGGCCGTGCTCGAGACGGAGCAGGAGGAGCGGATGCTGGTCGAGGA
GACCGTCGACGTGACGCTCCCGACCGACCGGGTGCCCACGGGTGCCCGCCACCCGCTCACGACGGGCGCCGAGCTGATCG
CCGACATCTTCGTCGCGATGGGCTGGGAGGTCGCCGAGGGGCCGGTCATCGAGGCCGAGTGGCTCAACTTCGACGCCCTC
AACCTCGGTCCCGACCATCCGGCTCGCACCATGCAGGACACGTTCTGGACCGAGCCCGCCGACCACGGGATGGTGCTGCG
CACCCACACCTCACCGGTCCAGGCCCGGACGATGCTCACCCGCACCCCGCCGATCTACGTCGTGTGTCCCGGGCGCGTCT
TCCGCACCGACGAGTACGACGCCACGCACAGCCCCGTCTTCCACCAGGTCGAGGGCCTCGCGGTCGACGAGGGCATCACG
ATGGCGCACCTCAAGGGCACCCTCGACCACTTCGCGGCCGCGATGTTCGGCGCGGGCATCAGCACCCGGTTCCGGCCGTC
GTACTTCCCGTTCACCGAGCCCAGCGCCGAGGTCGACCTGGTCTGCTTCGTGTGCCGCGGGGCCGGCGAGCTCGACGGCG
CGCCGTGCCGCACCTGCCGGGGCGAGGGCTGGATCGAGTGGGGCGGCTGCGGCGTGGTCAACCCACGGGTGCTCACCGCC
TGCGGCGTCGACGCCCAGCGCTACACGGGCTTCGCGTTCGGCATGGGCATCGACCGCACCCTGATGTTCCGCCACGGCAT
CGAGGACCTGCGCGAGCTGTTCGAGGGCGACGTCCGGTTCACCACGGCCTTCGGAACGGAGCTCTGA

Upstream 100 bases:

>100_bases
CCAGTGGGCCTGCGGACGAGCGGGACAACCGGTTCGCGCCGCTCACAGGCTGCTCCCTAGACTCGGGGGGCACACGAACC
CGAACGACGAGAGGCGTCCC

Downstream 100 bases:

>100_bases
GCCAGCCATGAAGACCCCCGTCTCCTGGATCCGCGAGCACGTCGACCTCCCCGACGGTGTCACCACCGAGGACCTGACGC
GCCGGCTGACTGCCCTGGGC

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS [H]

Number of amino acids: Translated: 368; Mature: 367

Protein sequence:

>368_residues
MSGPNTDYDPVEVTPLQPEEVEAARDAALAAIAAAGDLTELKQARLEHAGDRSPLALANREIGALPPQARKEAGQRIGQA
RGAVNQALAARQAVLETEQEERMLVEETVDVTLPTDRVPTGARHPLTTGAELIADIFVAMGWEVAEGPVIEAEWLNFDAL
NLGPDHPARTMQDTFWTEPADHGMVLRTHTSPVQARTMLTRTPPIYVVCPGRVFRTDEYDATHSPVFHQVEGLAVDEGIT
MAHLKGTLDHFAAAMFGAGISTRFRPSYFPFTEPSAEVDLVCFVCRGAGELDGAPCRTCRGEGWIEWGGCGVVNPRVLTA
CGVDAQRYTGFAFGMGIDRTLMFRHGIEDLRELFEGDVRFTTAFGTEL

Sequences:

>Translated_368_residues
MSGPNTDYDPVEVTPLQPEEVEAARDAALAAIAAAGDLTELKQARLEHAGDRSPLALANREIGALPPQARKEAGQRIGQA
RGAVNQALAARQAVLETEQEERMLVEETVDVTLPTDRVPTGARHPLTTGAELIADIFVAMGWEVAEGPVIEAEWLNFDAL
NLGPDHPARTMQDTFWTEPADHGMVLRTHTSPVQARTMLTRTPPIYVVCPGRVFRTDEYDATHSPVFHQVEGLAVDEGIT
MAHLKGTLDHFAAAMFGAGISTRFRPSYFPFTEPSAEVDLVCFVCRGAGELDGAPCRTCRGEGWIEWGGCGVVNPRVLTA
CGVDAQRYTGFAFGMGIDRTLMFRHGIEDLRELFEGDVRFTTAFGTEL
>Mature_367_residues
SGPNTDYDPVEVTPLQPEEVEAARDAALAAIAAAGDLTELKQARLEHAGDRSPLALANREIGALPPQARKEAGQRIGQAR
GAVNQALAARQAVLETEQEERMLVEETVDVTLPTDRVPTGARHPLTTGAELIADIFVAMGWEVAEGPVIEAEWLNFDALN
LGPDHPARTMQDTFWTEPADHGMVLRTHTSPVQARTMLTRTPPIYVVCPGRVFRTDEYDATHSPVFHQVEGLAVDEGITM
AHLKGTLDHFAAAMFGAGISTRFRPSYFPFTEPSAEVDLVCFVCRGAGELDGAPCRTCRGEGWIEWGGCGVVNPRVLTAC
GVDAQRYTGFAFGMGIDRTLMFRHGIEDLRELFEGDVRFTTAFGTEL

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI4758340, Length=292, Percent_Identity=30.1369863013699, Blast_Score=120, Evalue=2e-27,
Organism=Escherichia coli, GI1788007, Length=338, Percent_Identity=45.5621301775148, Blast_Score=292, Evalue=3e-80,
Organism=Caenorhabditis elegans, GI17508957, Length=289, Percent_Identity=28.719723183391, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI32563657, Length=289, Percent_Identity=28.719723183391, Blast_Score=117, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6321087, Length=279, Percent_Identity=29.7491039426523, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI18858079, Length=279, Percent_Identity=29.7491039426523, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978 [H]

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d [H]

EC number: =6.1.1.20 [H]

Molecular weight: Translated: 40016; Mature: 39884

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGPNTDYDPVEVTPLQPEEVEAARDAALAAIAAAGDLTELKQARLEHAGDRSPLALANR
CCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECCC
EIGALPPQARKEAGQRIGQARGAVNQALAARQAVLETEQEERMLVEETVDVTLPTDRVPT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEEEECCCCCCC
GARHPLTTGAELIADIFVAMGWEVAEGPVIEAEWLNFDALNLGPDHPARTMQDTFWTEPA
CCCCCCCHHHHHHHHHHHHCCCEECCCCEEEEECCCEEEECCCCCCCHHHHHHHHCCCCC
DHGMVLRTHTSPVQARTMLTRTPPIYVVCPGRVFRTDEYDATHSPVFHQVEGLAVDEGIT
CCCEEEEECCCCHHHHHHEECCCCEEEECCCEEEECCCCCCCCCCHHHHHCCEEECCCCE
MAHLKGTLDHFAAAMFGAGISTRFRPSYFPFTEPSAEVDLVCFVCRGAGELDGAPCRTCR
EHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
GEGWIEWGGCGVVNPRVLTACGVDAQRYTGFAFGMGIDRTLMFRHGIEDLRELFEGDVRF
CCCCEEECCCCCCCCCEEEECCCCHHHHCCEEECCCCCHHHHHHHCHHHHHHHHCCCEEE
TTAFGTEL
EEECCCCC
>Mature Secondary Structure 
SGPNTDYDPVEVTPLQPEEVEAARDAALAAIAAAGDLTELKQARLEHAGDRSPLALANR
CCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEECCC
EIGALPPQARKEAGQRIGQARGAVNQALAARQAVLETEQEERMLVEETVDVTLPTDRVPT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEEEECCCCCCC
GARHPLTTGAELIADIFVAMGWEVAEGPVIEAEWLNFDALNLGPDHPARTMQDTFWTEPA
CCCCCCCHHHHHHHHHHHHCCCEECCCCEEEEECCCEEEECCCCCCCHHHHHHHHCCCCC
DHGMVLRTHTSPVQARTMLTRTPPIYVVCPGRVFRTDEYDATHSPVFHQVEGLAVDEGIT
CCCEEEEECCCCHHHHHHEECCCCEEEECCCEEEECCCCCCCCCCHHHHHCCEEECCCCE
MAHLKGTLDHFAAAMFGAGISTRFRPSYFPFTEPSAEVDLVCFVCRGAGELDGAPCRTCR
EHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCC
GEGWIEWGGCGVVNPRVLTACGVDAQRYTGFAFGMGIDRTLMFRHGIEDLRELFEGDVRF
CCCCEEECCCCCCCCCEEEECCCCHHHHCCEEECCCCCHHHHHHHCHHHHHHHHCCCEEE
TTAFGTEL
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA