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The map label for this gene is infC [H]

Identifier: 119716685

GI number: 119716685

Start: 2618629

End: 2619360

Strand: Direct

Name: infC [H]

Synonym: Noca_2459

Alternate gene names: 119716685

Gene position: 2618629-2619360 (Clockwise)

Preceding gene: 119716684

Following gene: 119716686

Centisome position: 52.52

GC content: 66.8

Gene sequence:

>732_bases
GTGACGAGCGGCAGAGACCTCCGGCCACAAAGCCATCCAGGAGGACACATCAGCACCGAGCTGCGAATCAACGAGCGGAT
CCGGGTTCCCGAGGTCCGGCTCGTTGGACCCAACGGGGAGACCGTGGGCATCGTGCCCACCGATCAGGCCCTGAAGCTTG
CGCAGGAGGCGGACCTCGACCTCGTCGAGATCGCCCCGCAGGGGAAGCCGCCCGTCTGCAAGCTCATGGACTACGGGAAG
TTCAAGTACGAGAACGCCCAGAAGGCTCGTGAGGCCCGTCGCAACCAGACGAACGTGATCATCAAGGAGATGAAGCTTCG
TCCGAAGATCGACGCGCACGACTACGAGACCAAGAAGGGTCACGTGGTGCGGTTCCTGCGCGCCGGGGACAAGGTCAAGA
TCACGATCATGTTCCGTGGCCGCGAGCAGCACCGCCCCGAGCTGGGCTTCCGGCTGCTCCAGCGTCTCGCCGAGGACGTC
ACCGAGCTGGGCTTCGTCGAGTCCGCGCCCAAGCAGGACGGGCGCAACATGATCATGGTGCTCGGCCCGCACAAGAAGAA
GGCCGACGCGAAGGTCGACCTGAAGGCCGAGAAGGAGTCGCGAGCCGCCGAGCGCGCCGCGCACGAGGCGGAGGAGCGCG
CCGAGCGCGACGCCGCCCACGCGGCCGGGCCGGTCGCCCAGAAGAAGGAGCGAGGCCGCTCCGAGAACCTCGATCCCGAG
ATCGAGGCCTGA

Upstream 100 bases:

>100_bases
GGGCCCTCGGTGGCGAACCCCGCGCTCGGGGGGCGTCGGACTGGCTTCCGCTTGCACACCAGCGGAAGCCTTTGTTGATT
TCGCACCACCCTCTCGGGGG

Downstream 100 bases:

>100_bases
GAACAACCCGGCCGGTGGTCGACCCGGACCACCGCCGTGCACGGTGTCGAGCGCGACGTCGAGACCACGCCCAGCAGGAC
GAGAAGAGAGAGCAGAGATG

Product: translation initiation factor 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTSGRDLRPQSHPGGHISTELRINERIRVPEVRLVGPNGETVGIVPTDQALKLAQEADLDLVEIAPQGKPPVCKLMDYGK
FKYENAQKAREARRNQTNVIIKEMKLRPKIDAHDYETKKGHVVRFLRAGDKVKITIMFRGREQHRPELGFRLLQRLAEDV
TELGFVESAPKQDGRNMIMVLGPHKKKADAKVDLKAEKESRAAERAAHEAEERAERDAAHAAGPVAQKKERGRSENLDPE
IEA

Sequences:

>Translated_243_residues
MTSGRDLRPQSHPGGHISTELRINERIRVPEVRLVGPNGETVGIVPTDQALKLAQEADLDLVEIAPQGKPPVCKLMDYGK
FKYENAQKAREARRNQTNVIIKEMKLRPKIDAHDYETKKGHVVRFLRAGDKVKITIMFRGREQHRPELGFRLLQRLAEDV
TELGFVESAPKQDGRNMIMVLGPHKKKADAKVDLKAEKESRAAERAAHEAEERAERDAAHAAGPVAQKKERGRSENLDPE
IEA
>Mature_242_residues
TSGRDLRPQSHPGGHISTELRINERIRVPEVRLVGPNGETVGIVPTDQALKLAQEADLDLVEIAPQGKPPVCKLMDYGKF
KYENAQKAREARRNQTNVIIKEMKLRPKIDAHDYETKKGHVVRFLRAGDKVKITIMFRGREQHRPELGFRLLQRLAEDVT
ELGFVESAPKQDGRNMIMVLGPHKKKADAKVDLKAEKESRAAERAAHEAEERAERDAAHAAGPVAQKKERGRSENLDPEI
EA

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=167, Percent_Identity=50.2994011976048, Blast_Score=156, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 27338; Mature: 27206

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSGRDLRPQSHPGGHISTELRINERIRVPEVRLVGPNGETVGIVPTDQALKLAQEADLD
CCCCCCCCCCCCCCCCEEEEEEECCEECCCEEEEECCCCCEEEEECCHHHHHHHHHCCCC
LVEIAPQGKPPVCKLMDYGKFKYENAQKAREARRNQTNVIIKEMKLRPKIDAHDYETKKG
EEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCHHEEEEEHHCCCCCCCCCCCCCCC
HVVRFLRAGDKVKITIMFRGREQHRPELGFRLLQRLAEDVTELGFVESAPKQDGRNMIMV
CEEEEEECCCEEEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
LGPHKKKADAKVDLKAEKESRAAERAAHEAEERAERDAAHAAGPVAQKKERGRSENLDPE
ECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
IEA
CCC
>Mature Secondary Structure 
TSGRDLRPQSHPGGHISTELRINERIRVPEVRLVGPNGETVGIVPTDQALKLAQEADLD
CCCCCCCCCCCCCCCEEEEEEECCEECCCEEEEECCCCCEEEEECCHHHHHHHHHCCCC
LVEIAPQGKPPVCKLMDYGKFKYENAQKAREARRNQTNVIIKEMKLRPKIDAHDYETKKG
EEEECCCCCCCHHHHHCCCCCCCCCHHHHHHHHCCCHHEEEEEHHCCCCCCCCCCCCCCC
HVVRFLRAGDKVKITIMFRGREQHRPELGFRLLQRLAEDVTELGFVESAPKQDGRNMIMV
CEEEEEECCCEEEEEEEECCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
LGPHKKKADAKVDLKAEKESRAAERAAHEAEERAERDAAHAAGPVAQKKERGRSENLDPE
ECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
IEA
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572948; 12692562 [H]