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The map label for this gene is ribE [H]

Identifier: 119716674

GI number: 119716674

Start: 2610526

End: 2611179

Strand: Direct

Name: ribE [H]

Synonym: Noca_2448

Alternate gene names: 119716674

Gene position: 2610526-2611179 (Clockwise)

Preceding gene: 119716673

Following gene: 119716675

Centisome position: 52.36

GC content: 72.02

Gene sequence:

>654_bases
ATGTTCACCGGGATCGTCGAGGAGCTCGGCACCGTCGCCGCCGTGGAGGACCAGGGCGACGCGATCCGCCTCACCATCCG
GGCCACCACTGTGCTCGAGGACGCTGCGCTCGGCGACTCGATCGCAGTCAACGGCTGCTGCCTCACCGTCGCGGCTCGCG
ACGGGGACACCTGGACCGCCGACGTCATGCAGGAGACCCTCGACAAGACCAGCCTCGCCGGCGTCCGGCCCGGCGACCGC
GTGAACCTCGAGCGAGCGGTCACGGCGCACACGCGGCTCGGTGGCCACATCGTCCAGGGCCACGTCGACGGCGTGGGGAC
CGTCGTCCGCCGGACCCCGAGCGAGCACTGGGAGGTCGTCGAGATCTCCTTCCCGCCGGCGGACCAGCGGGGCACGCTGG
CCCGCTACCTCGTCGACAAGGGCTCGATCACCGTCGACGGCGTCAGCCTGACCGTCGTCGAGGCCACCGCGGACGGCTTC
ACCGTGAGCCTGATCCCGGAGACCCTGGCCCGCACGACCCTCGGCACCCGCCGTCCGGGCGACCGGGTGAACCTCGAGGC
CGACATCCTCGCCAAGCACGTCGAGCGACTGCTGGCCCACCGTGACCAGGTCGACCGAGTCGGGGCCGACCGCACCGAAG
GAGCACCCGCATGA

Upstream 100 bases:

>100_bases
GGGTCACCGACGTCACGGTGCTCGAGGGGCTCGACGGCGAGCAGCCGAACGTGCGCCTGACCCTCACCCCTTCAGAACCC
CGCGCAGAAGGAGCCTGACC

Downstream 100 bases:

>100_bases
GCACCGAGATCAGGCTCGACACCGTCGAGCGGGCGATCGCCGACATCGCCGCCGGCAAGGCCGTGGTCGTCGTCGACGAC
GAGGACCGCGAGAACGAGGG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MFTGIVEELGTVAAVEDQGDAIRLTIRATTVLEDAALGDSIAVNGCCLTVAARDGDTWTADVMQETLDKTSLAGVRPGDR
VNLERAVTAHTRLGGHIVQGHVDGVGTVVRRTPSEHWEVVEISFPPADQRGTLARYLVDKGSITVDGVSLTVVEATADGF
TVSLIPETLARTTLGTRRPGDRVNLEADILAKHVERLLAHRDQVDRVGADRTEGAPA

Sequences:

>Translated_217_residues
MFTGIVEELGTVAAVEDQGDAIRLTIRATTVLEDAALGDSIAVNGCCLTVAARDGDTWTADVMQETLDKTSLAGVRPGDR
VNLERAVTAHTRLGGHIVQGHVDGVGTVVRRTPSEHWEVVEISFPPADQRGTLARYLVDKGSITVDGVSLTVVEATADGF
TVSLIPETLARTTLGTRRPGDRVNLEADILAKHVERLLAHRDQVDRVGADRTEGAPA
>Mature_217_residues
MFTGIVEELGTVAAVEDQGDAIRLTIRATTVLEDAALGDSIAVNGCCLTVAARDGDTWTADVMQETLDKTSLAGVRPGDR
VNLERAVTAHTRLGGHIVQGHVDGVGTVVRRTPSEHWEVVEISFPPADQRGTLARYLVDKGSITVDGVSLTVVEATADGF
TVSLIPETLARTTLGTRRPGDRVNLEADILAKHVERLLAHRDQVDRVGADRTEGAPA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=208, Percent_Identity=38.9423076923077, Blast_Score=130, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6319733, Length=219, Percent_Identity=37.8995433789954, Blast_Score=141, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23081; Mature: 23081

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVEELGTVAAVEDQGDAIRLTIRATTVLEDAALGDSIAVNGCCLTVAARDGDTWTA
CCCCHHHHHCCEEEEECCCCEEEEEEEEEEEEHHHHCCCCEEECCEEEEEEECCCCCEEH
DVMQETLDKTSLAGVRPGDRVNLERAVTAHTRLGGHIVQGHVDGVGTVVRRTPSEHWEVV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCEEEE
EISFPPADQRGTLARYLVDKGSITVDGVSLTVVEATADGFTVSLIPETLARTTLGTRRPG
EEECCCCCCCCCCEEEEECCCCEEECCEEEEEEEECCCCEEEEECHHHHHHHHCCCCCCC
DRVNLEADILAKHVERLLAHRDQVDRVGADRTEGAPA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MFTGIVEELGTVAAVEDQGDAIRLTIRATTVLEDAALGDSIAVNGCCLTVAARDGDTWTA
CCCCHHHHHCCEEEEECCCCEEEEEEEEEEEEHHHHCCCCEEECCEEEEEEECCCCCEEH
DVMQETLDKTSLAGVRPGDRVNLERAVTAHTRLGGHIVQGHVDGVGTVVRRTPSEHWEVV
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHCCCCCCEEEE
EISFPPADQRGTLARYLVDKGSITVDGVSLTVVEATADGFTVSLIPETLARTTLGTRRPG
EEECCCCCCCCCCEEEEECCCCEEECCEEEEEEEECCCCEEEEECHHHHHHHHCCCCCCC
DRVNLEADILAKHVERLLAHRDQVDRVGADRTEGAPA
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]