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The map label for this gene is sun [C]

Identifier: 119716670

GI number: 119716670

Start: 2605306

End: 2606724

Strand: Direct

Name: sun [C]

Synonym: Noca_2443

Alternate gene names: 119716670

Gene position: 2605306-2606724 (Clockwise)

Preceding gene: 119716669

Following gene: 119716671

Centisome position: 52.25

GC content: 75.83

Gene sequence:

>1419_bases
ATGAGCGATACCCGGCCTCGGGGCCACCAACGAGAGCCTCAGCGCGGGTCCCCGGGTGGGTCCCAGCGCGGCAACCGGCC
CCGCGTCGACCCGGCCCGGCTCGCGGCGCTCGACGTGATGAAGGCCGTGCGGGTCGACGGCGCCTACACGAATCTCGTCC
TGCCGTCGGTGCTGCGCCAGCACGGGCTCTCCGGCCGGGACGCCGCGTTCGTGACCGAGCTGGTGTCCGGCACCATCCGC
AGACGTGGGACGTACGACGCCATCCTGGCCGCCTGCGTCGACCGGCCCCTGAGCAAGGTGGAGGCCAAGGTCCTCGACGC
GCTGCGGCTCGGCACCCACCAGCTGCTCTCCATGCGGGTCCCGGTGCACGCGGCGATCAGCACGACGGTCGACCTGGTCC
GGGCCAAGGTCAGCTCGGGCGCGGGTGGCTTCGCGAACGCCGTCCTGCGCCAGGTGGCCCGGCAGGAGCTGACCGAGTGG
ATCGCCCGGGTCGCTCCGGACCCGCGGGTCGCGCCGACCCGGTTCGCCTCGATCGCCTACAGCCATCCACGCTGGATCGT
CGACGAGCTCCGCTCGGCCGTCGGCGCCGACGAGCTGTTCGAGCTGCTCGCGGCGGACAACGAGCCGCCGCGGGTGACGC
TCGTGGCTCGCCCCGGGCGGTCCGGCCGCGAGGAGCTGCCGGGTGAGCCGACCCCCTACTCGCCGTACGGCGTGGTCCTC
GGCGGGGGCGACCCGGGTGAGATCCCGGCGGTCGCCGAGGGCCGGGCGGGGGTCCAGGACGAGGGCTCGCAGCTGGTCGC
TGCGGCGCTCGCGGCCGCACCGATCGAGGGGCCCGACCGCCGCTGGCTCGACCTGTGCGCCGGTCCCGGCGGGAAGTCGG
CCTTGCTGGCCGCGCTGGCCGCCCAGCGGGGCGCCCGCCTGGTGGCCGCCGAGCGCCAGGAGCACCGGACCCGGCTGGTG
CTGCGCGCGCTGCGCGACGCGCCCGGTGTTGCTGGCATCGTGACGTCCGACGGCACCGCGCCGCCGTTCGCCGAGGGCAC
CTTCGACCGAGTGCTCGTCGACGCGCCCTGCACCGGCCTCGGCGCGCTCCGGCGCCGGCCCGAGGCCCGGTGGCGGCGCC
GGGCCGACGACCTGCTCAGCCTGGTGCTGCTCCAGCGACGCCTGCTCTCCTCCGCCCTCGACCTGGTCCGGCCCGGTGGC
GTGGTGGTCTACGCCACGTGCTCGCCGGTGATCTCCGAGACCCGGGGCGTGGTGTCCTCGGTGCTCGAGAGCCGCGACGA
CGCGGAGCCGGGGGACACGCGGTCGTTGCTGCCCGCGATCCCCGGCTGCGAGGGTCCGATGCCCGGAACGGTGCAGCTGT
GGCCGCACCGGCACGGCACCGACGCGATGTTCCTCGCGTTACTGCGGCGCACCGCCTGA

Upstream 100 bases:

>100_bases
AGCGCGAGGAGTGGGTGGAGATCGCCACCGATGCTGGGGCCGTCCAGGCCGTCCAGGCAGCACAGTCCGTCCGGAGCCCG
TCGACGAAGCGCCTCGCCGG

Downstream 100 bases:

>100_bases
GGGCTCACGGGCGCGACGAACGCGCCGTACACCTCGCCGACGAAGGTGTGCTCGCCGGCCTTGCCCGGGTCCTGGCGTGG
GGCGTTGTGGTCGATCCGCA

Product: Fmu (Sun) domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MSDTRPRGHQREPQRGSPGGSQRGNRPRVDPARLAALDVMKAVRVDGAYTNLVLPSVLRQHGLSGRDAAFVTELVSGTIR
RRGTYDAILAACVDRPLSKVEAKVLDALRLGTHQLLSMRVPVHAAISTTVDLVRAKVSSGAGGFANAVLRQVARQELTEW
IARVAPDPRVAPTRFASIAYSHPRWIVDELRSAVGADELFELLAADNEPPRVTLVARPGRSGREELPGEPTPYSPYGVVL
GGGDPGEIPAVAEGRAGVQDEGSQLVAAALAAAPIEGPDRRWLDLCAGPGGKSALLAALAAQRGARLVAAERQEHRTRLV
LRALRDAPGVAGIVTSDGTAPPFAEGTFDRVLVDAPCTGLGALRRRPEARWRRRADDLLSLVLLQRRLLSSALDLVRPGG
VVVYATCSPVISETRGVVSSVLESRDDAEPGDTRSLLPAIPGCEGPMPGTVQLWPHRHGTDAMFLALLRRTA

Sequences:

>Translated_472_residues
MSDTRPRGHQREPQRGSPGGSQRGNRPRVDPARLAALDVMKAVRVDGAYTNLVLPSVLRQHGLSGRDAAFVTELVSGTIR
RRGTYDAILAACVDRPLSKVEAKVLDALRLGTHQLLSMRVPVHAAISTTVDLVRAKVSSGAGGFANAVLRQVARQELTEW
IARVAPDPRVAPTRFASIAYSHPRWIVDELRSAVGADELFELLAADNEPPRVTLVARPGRSGREELPGEPTPYSPYGVVL
GGGDPGEIPAVAEGRAGVQDEGSQLVAAALAAAPIEGPDRRWLDLCAGPGGKSALLAALAAQRGARLVAAERQEHRTRLV
LRALRDAPGVAGIVTSDGTAPPFAEGTFDRVLVDAPCTGLGALRRRPEARWRRRADDLLSLVLLQRRLLSSALDLVRPGG
VVVYATCSPVISETRGVVSSVLESRDDAEPGDTRSLLPAIPGCEGPMPGTVQLWPHRHGTDAMFLALLRRTA
>Mature_471_residues
SDTRPRGHQREPQRGSPGGSQRGNRPRVDPARLAALDVMKAVRVDGAYTNLVLPSVLRQHGLSGRDAAFVTELVSGTIRR
RGTYDAILAACVDRPLSKVEAKVLDALRLGTHQLLSMRVPVHAAISTTVDLVRAKVSSGAGGFANAVLRQVARQELTEWI
ARVAPDPRVAPTRFASIAYSHPRWIVDELRSAVGADELFELLAADNEPPRVTLVARPGRSGREELPGEPTPYSPYGVVLG
GGDPGEIPAVAEGRAGVQDEGSQLVAAALAAAPIEGPDRRWLDLCAGPGGKSALLAALAAQRGARLVAAERQEHRTRLVL
RALRDAPGVAGIVTSDGTAPPFAEGTFDRVLVDAPCTGLGALRRRPEARWRRRADDLLSLVLLQRRLLSSALDLVRPGGV
VVYATCSPVISETRGVVSSVLESRDDAEPGDTRSLLPAIPGCEGPMPGTVQLWPHRHGTDAMFLALLRRTA

Specific function: May act as RNA methyltransferase [H]

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=344, Percent_Identity=29.3604651162791, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI76150623, Length=344, Percent_Identity=29.3604651162791, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI32698918, Length=178, Percent_Identity=32.0224719101124, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI11545785, Length=207, Percent_Identity=31.4009661835749, Blast_Score=76, Evalue=7e-14,
Organism=Escherichia coli, GI2367212, Length=428, Percent_Identity=29.6728971962617, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI87081985, Length=258, Percent_Identity=28.6821705426357, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17536757, Length=305, Percent_Identity=27.8688524590164, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324268, Length=227, Percent_Identity=28.6343612334802, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI22024126, Length=323, Percent_Identity=27.2445820433437, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21356513, Length=161, Percent_Identity=35.4037267080745, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24668781, Length=161, Percent_Identity=35.4037267080745, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50277; Mature: 50146

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTRPRGHQREPQRGSPGGSQRGNRPRVDPARLAALDVMKAVRVDGAYTNLVLPSVLRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HGLSGRDAAFVTELVSGTIRRRGTYDAILAACVDRPLSKVEAKVLDALRLGTHQLLSMRV
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVHAAISTTVDLVRAKVSSGAGGFANAVLRQVARQELTEWIARVAPDPRVAPTRFASIAY
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SHPRWIVDELRSAVGADELFELLAADNEPPRVTLVARPGRSGREELPGEPTPYSPYGVVL
CCCHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCCEEEE
GGGDPGEIPAVAEGRAGVQDEGSQLVAAALAAAPIEGPDRRWLDLCAGPGGKSALLAALA
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHH
AQRGARLVAAERQEHRTRLVLRALRDAPGVAGIVTSDGTAPPFAEGTFDRVLVDAPCTGL
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHEEECCCCCCH
GALRRRPEARWRRRADDLLSLVLLQRRLLSSALDLVRPGGVVVYATCSPVISETRGVVSS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHH
VLESRDDAEPGDTRSLLPAIPGCEGPMPGTVQLWPHRHGTDAMFLALLRRTA
HHHCCCCCCCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDTRPRGHQREPQRGSPGGSQRGNRPRVDPARLAALDVMKAVRVDGAYTNLVLPSVLRQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
HGLSGRDAAFVTELVSGTIRRRGTYDAILAACVDRPLSKVEAKVLDALRLGTHQLLSMRV
CCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PVHAAISTTVDLVRAKVSSGAGGFANAVLRQVARQELTEWIARVAPDPRVAPTRFASIAY
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
SHPRWIVDELRSAVGADELFELLAADNEPPRVTLVARPGRSGREELPGEPTPYSPYGVVL
CCCHHHHHHHHHHHCHHHHHHHHHCCCCCCEEEEEECCCCCCHHHCCCCCCCCCCCEEEE
GGGDPGEIPAVAEGRAGVQDEGSQLVAAALAAAPIEGPDRRWLDLCAGPGGKSALLAALA
ECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHH
AQRGARLVAAERQEHRTRLVLRALRDAPGVAGIVTSDGTAPPFAEGTFDRVLVDAPCTGL
HHCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHEEECCCCCCH
GALRRRPEARWRRRADDLLSLVLLQRRLLSSALDLVRPGGVVVYATCSPVISETRGVVSS
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHH
VLESRDDAEPGDTRSLLPAIPGCEGPMPGTVQLWPHRHGTDAMFLALLRRTA
HHHCCCCCCCCCCHHHHCCCCCCCCCCCCCEEECCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]