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The map label for this gene is pyrR [H]

Identifier: 119716654

GI number: 119716654

Start: 2587676

End: 2588290

Strand: Direct

Name: pyrR [H]

Synonym: Noca_2427

Alternate gene names: 119716654

Gene position: 2587676-2588290 (Clockwise)

Preceding gene: 161485634

Following gene: 119716655

Centisome position: 51.9

GC content: 72.85

Gene sequence:

>615_bases
ATGCCTGCGCACCCTCAAGCCGTGCCCCCCGGTCCGTCGTCCAGCACGGACCGCGCCCACCCCGTCCGCACCGTCCTCGA
CGAGCGTGACATCGGCCGGGCCCTGACCCGGATCTCCCACGAGATCCTCGAGCGCAACAAGGGCGCCACCGACCTGGTTC
TGCTCGGCATCCCCAGCCGCGGGGTCCCGCTCGCCGAGCGGATCGCCGAGCGGATCAGCACCGTCGAGGGGTACGCCGTC
CCCGTCGGCTCCCTCGACGTCACCATGTACCGCGACGACCTGCGGATGAAGCCGGCCCGCACGCTGCTGCCCACGCAGAT
CCCGGCCGGCGGCATCGACGGGCGCACCGTCGTGCTCGTCGACGACGTGCTGTTCTCCGGACGCACCATCCGGGCCGCGC
TCGACGCGCTCAACGACCTGGGCCGCCCGCGAGCGGTCCAGCTGGCCGTGCTCGTCGACCGCGGCCACCGGGAGCTGCCG
ATCCGTGCCGACTTCGTCGGCAAGAACCTCCCGACGTCGCTCGTCGAGCGGGTCCGGGTCAGCCTGGTGGGCATCGACGA
CGTCGATGCGGTCACCATCCAGGGCACGGCGCCCGCCGGGGAGGTGACCGCATGA

Upstream 100 bases:

>100_bases
GGGGGCGGGCGCGCCGCGAGCGCGCGGAGGAGTAGGGTCGTCCTCGATCGACATCCTTTAACGAGCCGTCCTGTGAGGCG
GAGAAGGAGGTCCGAGGCTC

Downstream 100 bases:

>100_bases
AGCGGCACCTGCTGAGCGCGGGCGACCTGAGCCGCGACGACGCGGAGCTGGTGCTCCGGACCGCCGCCGAGCTGCGCGAG
CTCGCCGACCGGCCGATCAA

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MPAHPQAVPPGPSSSTDRAHPVRTVLDERDIGRALTRISHEILERNKGATDLVLLGIPSRGVPLAERIAERISTVEGYAV
PVGSLDVTMYRDDLRMKPARTLLPTQIPAGGIDGRTVVLVDDVLFSGRTIRAALDALNDLGRPRAVQLAVLVDRGHRELP
IRADFVGKNLPTSLVERVRVSLVGIDDVDAVTIQGTAPAGEVTA

Sequences:

>Translated_204_residues
MPAHPQAVPPGPSSSTDRAHPVRTVLDERDIGRALTRISHEILERNKGATDLVLLGIPSRGVPLAERIAERISTVEGYAV
PVGSLDVTMYRDDLRMKPARTLLPTQIPAGGIDGRTVVLVDDVLFSGRTIRAALDALNDLGRPRAVQLAVLVDRGHRELP
IRADFVGKNLPTSLVERVRVSLVGIDDVDAVTIQGTAPAGEVTA
>Mature_203_residues
PAHPQAVPPGPSSSTDRAHPVRTVLDERDIGRALTRISHEILERNKGATDLVLLGIPSRGVPLAERIAERISTVEGYAVP
VGSLDVTMYRDDLRMKPARTLLPTQIPAGGIDGRTVVLVDDVLFSGRTIRAALDALNDLGRPRAVQLAVLVDRGHRELPI
RADFVGKNLPTSLVERVRVSLVGIDDVDAVTIQGTAPAGEVTA

Specific function: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 21833; Mature: 21702

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAHPQAVPPGPSSSTDRAHPVRTVLDERDIGRALTRISHEILERNKGATDLVLLGIPSR
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GVPLAERIAERISTVEGYAVPVGSLDVTMYRDDLRMKPARTLLPTQIPAGGIDGRTVVLV
CCCHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCEEEEE
DDVLFSGRTIRAALDALNDLGRPRAVQLAVLVDRGHRELPIRADFVGKNLPTSLVERVRV
ECHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCHHHHHHHHH
SLVGIDDVDAVTIQGTAPAGEVTA
EEECCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
PAHPQAVPPGPSSSTDRAHPVRTVLDERDIGRALTRISHEILERNKGATDLVLLGIPSR
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCC
GVPLAERIAERISTVEGYAVPVGSLDVTMYRDDLRMKPARTLLPTQIPAGGIDGRTVVLV
CCCHHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCEEEEE
DDVLFSGRTIRAALDALNDLGRPRAVQLAVLVDRGHRELPIRADFVGKNLPTSLVERVRV
ECHHHCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCEEHHHCCCCCCHHHHHHHHH
SLVGIDDVDAVTIQGTAPAGEVTA
EEECCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]