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The map label for this gene is arcD [H]

Identifier: 119716650

GI number: 119716650

Start: 2582618

End: 2584087

Strand: Direct

Name: arcD [H]

Synonym: Noca_2423

Alternate gene names: 119716650

Gene position: 2582618-2584087 (Clockwise)

Preceding gene: 119716649

Following gene: 119716651

Centisome position: 51.8

GC content: 69.46

Gene sequence:

>1470_bases
ATGACTCAGCAGATGGTCCGACCACCGTCGGGCCCGAGCCCTGAGCAGTCCGCGAGAGGCGCCGGCACCCTGGCGCTGCC
CGCCCTGATCGCCCTCGTCGTGGGGTCCATGATCGGTAGCGGCATCTTCGCGCTGCCCTCGCAGATGGCCGGGAGCGCTG
CTCCCGGGCCGCTGCTCATCGGCTGGCTGGTGACCGGCGTCGGCATGCTGATGCTGGCGTTCGTGTTCCAGACCCTGTCG
CGCCGCAAGCCCGACGTGGACGGCGGCGTCTACGGATACGCCCGCGCCGGCTTCGGCAACTACCTCGGCTTCACCTCGGC
CTGGGGCTACTGGATCAGTGCCTGGATCGGCAACGTGGGCTACCTCGTCCTGCTGATGTCGACGCTGGGCTACTTCGTGC
CGGCGTTCGAGGGCGGCAACACCGTGGCGGCCATCATCGGGGCCTCCGTCGTGCTGTGGGTCGTCCAGGCGCTGACGCTG
CGCGGCGTCCAGAGCGCCGCGTTCGTCAACACCCTCGTGACGATCGCCAAGATCGTGCCGCTCCTGACCTTCATCGCGAT
CGCAGCCGTCGGCTTCAAGGCCGGTATCTTCACCGCCGACGTGTGGGGCGACAGTGCGGGCCTCGGCTCCACCCTGGACC
AGGTCAAGAACATGATGCTGGTCACCGTCTGGGTGTTCATCGGCATCGAGGGTGCCGCGGTCTACAGCCAGCGCGCCACC
CGGCGCAGCGACGTCGGCCGGGCGACCGTGATCGGCTTCGTCGGCGTACTGGCGCTGCTGCTCGCCGTCAACGTGCTCTC
CTACGGCCTGATGAGCCAGGCCAAGCTGGCCGGGCTCGAAGACCCGTCGATGGCGGGCCTGATGCGGCAGGAGGTCGGCG
CCTGGGGCACCGGCTTCATCTCGATCGGGCTCGCGGTCTCGGTGGCCGGCGCGCTCCTCGCCTGGGTGCTCCTGAGCGTG
GAGATCCTGCGGCTGCCCGCCCGGGAGGGCGTGCTCCCGCGCCAGCTCGGCACGGAGAACCGGTACGGCGCACCATCGGT
CGCCCTGTGGCTGACCAGCGGTTGCGTCCAGCTGATGCTGCTGTGGACCCTGGTCAACGAGAACACCTACACCGACCTGA
TCTACCTGGCGACCTCCCTGATCCTGCTGCCGTACCTCTGGTCGGCGCTCTACCAGGTCAAGCTGGCGATCAGCGGTGAG
TCCTACGCCCAGGGCGAGAGCCGGACGCGCGACCTCCTGGTCGGACTGGTGGCCCTCGCCTACGCCGTGTGGCTGGTCTA
CGCGGGTGGCTGGGAGTACGTGCTGGTCGCCGGCATCTTCTACCTGGTCGGCACCGCGCTCTACGTCTGGGCACGCTCGC
AGGCCCGGGCCGCGATCTTCACGGTCGCCGAGCGCGCGGTCGTGGCCGTGGTCGTCGGCCTCTCCATCGCCGGCGTCATC
GGCCTGGTCCAGGGCTTCGTCTCGATCTGA

Upstream 100 bases:

>100_bases
TCGTGCCGTTCGTCCCTGCTGCGGACCTGTCGTGGCCTCCTAGCGTCCTTCACAGGACGGGAGATCGGTCTTCCGTCTCC
TGAAGGAGGCCCTAGAAACC

Downstream 100 bases:

>100_bases
CGGAGCCGGCTCCACCCGCTCGGGGGCGGGGCGGTCCTCGGGCCGCCGCCCCGCCCGACCGGCCGCTTCCGCGCGCCGTC
CGGGCACCCCGTCGACACTT

Product: arginine/ornithine antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MTQQMVRPPSGPSPEQSARGAGTLALPALIALVVGSMIGSGIFALPSQMAGSAAPGPLLIGWLVTGVGMLMLAFVFQTLS
RRKPDVDGGVYGYARAGFGNYLGFTSAWGYWISAWIGNVGYLVLLMSTLGYFVPAFEGGNTVAAIIGASVVLWVVQALTL
RGVQSAAFVNTLVTIAKIVPLLTFIAIAAVGFKAGIFTADVWGDSAGLGSTLDQVKNMMLVTVWVFIGIEGAAVYSQRAT
RRSDVGRATVIGFVGVLALLLAVNVLSYGLMSQAKLAGLEDPSMAGLMRQEVGAWGTGFISIGLAVSVAGALLAWVLLSV
EILRLPAREGVLPRQLGTENRYGAPSVALWLTSGCVQLMLLWTLVNENTYTDLIYLATSLILLPYLWSALYQVKLAISGE
SYAQGESRTRDLLVGLVALAYAVWLVYAGGWEYVLVAGIFYLVGTALYVWARSQARAAIFTVAERAVVAVVVGLSIAGVI
GLVQGFVSI

Sequences:

>Translated_489_residues
MTQQMVRPPSGPSPEQSARGAGTLALPALIALVVGSMIGSGIFALPSQMAGSAAPGPLLIGWLVTGVGMLMLAFVFQTLS
RRKPDVDGGVYGYARAGFGNYLGFTSAWGYWISAWIGNVGYLVLLMSTLGYFVPAFEGGNTVAAIIGASVVLWVVQALTL
RGVQSAAFVNTLVTIAKIVPLLTFIAIAAVGFKAGIFTADVWGDSAGLGSTLDQVKNMMLVTVWVFIGIEGAAVYSQRAT
RRSDVGRATVIGFVGVLALLLAVNVLSYGLMSQAKLAGLEDPSMAGLMRQEVGAWGTGFISIGLAVSVAGALLAWVLLSV
EILRLPAREGVLPRQLGTENRYGAPSVALWLTSGCVQLMLLWTLVNENTYTDLIYLATSLILLPYLWSALYQVKLAISGE
SYAQGESRTRDLLVGLVALAYAVWLVYAGGWEYVLVAGIFYLVGTALYVWARSQARAAIFTVAERAVVAVVVGLSIAGVI
GLVQGFVSI
>Mature_488_residues
TQQMVRPPSGPSPEQSARGAGTLALPALIALVVGSMIGSGIFALPSQMAGSAAPGPLLIGWLVTGVGMLMLAFVFQTLSR
RKPDVDGGVYGYARAGFGNYLGFTSAWGYWISAWIGNVGYLVLLMSTLGYFVPAFEGGNTVAAIIGASVVLWVVQALTLR
GVQSAAFVNTLVTIAKIVPLLTFIAIAAVGFKAGIFTADVWGDSAGLGSTLDQVKNMMLVTVWVFIGIEGAAVYSQRATR
RSDVGRATVIGFVGVLALLLAVNVLSYGLMSQAKLAGLEDPSMAGLMRQEVGAWGTGFISIGLAVSVAGALLAWVLLSVE
ILRLPAREGVLPRQLGTENRYGAPSVALWLTSGCVQLMLLWTLVNENTYTDLIYLATSLILLPYLWSALYQVKLAISGES
YAQGESRTRDLLVGLVALAYAVWLVYAGGWEYVLVAGIFYLVGTALYVWARSQARAAIFTVAERAVVAVVVGLSIAGVIG
LVQGFVSI

Specific function: Catalyzes an electroneutral exchange between arginine and ornithine to allow high-efficiency energy conversion in the arginine deiminase pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI1787890, Length=435, Percent_Identity=42.7586206896552, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI2367353, Length=424, Percent_Identity=28.3018867924528, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1790575, Length=388, Percent_Identity=27.319587628866, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786908, Length=434, Percent_Identity=24.8847926267281, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004754
- InterPro:   IPR022461 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51463; Mature: 51332

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHCC
>Mature Secondary Structure 
TQQMVRPPSGPSPEQSARGAGTLALPALIALVVGSMIGSGIFALPSQMAGSAAPGPLLI
CCCCCCCCCCCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCHHHCCHHHCCCCCCCHHHH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HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2158926; 10984043; 1311296 [H]