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The map label for this gene is lig [H]

Identifier: 119716498

GI number: 119716498

Start: 2421762

End: 2422718

Strand: Direct

Name: lig [H]

Synonym: Noca_2271

Alternate gene names: 119716498

Gene position: 2421762-2422718 (Clockwise)

Preceding gene: 119716495

Following gene: 119716500

Centisome position: 48.57

GC content: 71.37

Gene sequence:

>957_bases
GTGCCGACCACCTGGGAGCCGATGCTGGCCAAGCCGGCAGCCACGCTGCCAGCGGTCGGCGGCCTGCTGGGCGGCACCGT
CTACGAACCGAAGTGGGATGGCTACCGGGCCATCCTCGAGCGCACGGGCGCAGGGTGCCGGGTGTGGTCACGCAAGGGCG
CCGACCTAGCGGCAGGGTTCCCCGAGATCGTCCAAGCCGCCCTCGAGCGGCTGGAGCCGGGCACGGTGATCGACGGTGAA
CTCGTCGTGTGGCGGGACGGCCGACTCGACTTCGGGGCACTGGCCCCGCGGCTGGCATACCGCGGCCGCCGCAGGTCGCC
GGCGGACCTCCCACCTGCCTCCTTCCTAGCTTTCGACGTCTTGGTTGCAGGCGACGTCGACCTGCGGACCAAGCCGCTGC
GCGATCGCCGGGCAGTGCTCGAGCAGTTGGCGGGATCGTGGCAGCCGCCGATGCAGCTGACGCCGCAGACCGCGGACCCG
GCGGAGGCGCAGCGCTGGCTGACGGAGTACGACGCGGCGGACGTCGGTGTGGAGGGCCTGGTCGCCAAGGGAGCCGGTCA
GCGCTACCTGCCTGGTCAGCGGGGGTGGGTGAAGTTCCGTATCCGCAACACTCGCGAGGCCACGGTCGGGGCGGTCATCG
GTCGTGTCGACCAACCGGTTCGGCTGATCCTCGGCCTCCGAGACGCCGCTGGCACGTTGCGTGTGGCCGGCGCGACCCAT
CCGCTCACTCCGAGGGAGTCGGTCGAGCTCGCCTCGGTGCTCGTCGGCACCGATGACCACCCGTGGCCGGCTGAACTCGG
CACCCGTCAGCTGGGGCGTTTCAGCCGCGAGCCGGTTGCGATCACCCGGGTGATCCCCACGGTGATCGTCGAGGTTGAGG
CAGACACCGCGTTTGAGCACGGCCGGTGGCGGCACCTGACCCGTTACCGCCGGCTGCGCCTGGACCGCTCCAGCTGA

Upstream 100 bases:

>100_bases
GGGATGCCCGCCCCGCGCCCGTAGCCGCCGCCCACCATGGCCCATAGCGTAGAACACTTGTTCGAAGTGATGGGCGGCGT
TGGTTTCGTACGCTGAATGG

Downstream 100 bases:

>100_bases
GGATCGACCCTCGCGGTCGACGCGGAGAGAGGAATGCGCCAGCCCGGCCGCAGCTGCTCCCGAATGCGCTCGAGCGCCTC
GTCGTAGGACGCCGCGGTGG

Product: ATP dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPTTWEPMLAKPAATLPAVGGLLGGTVYEPKWDGYRAILERTGAGCRVWSRKGADLAAGFPEIVQAALERLEPGTVIDGE
LVVWRDGRLDFGALAPRLAYRGRRRSPADLPPASFLAFDVLVAGDVDLRTKPLRDRRAVLEQLAGSWQPPMQLTPQTADP
AEAQRWLTEYDAADVGVEGLVAKGAGQRYLPGQRGWVKFRIRNTREATVGAVIGRVDQPVRLILGLRDAAGTLRVAGATH
PLTPRESVELASVLVGTDDHPWPAELGTRQLGRFSREPVAITRVIPTVIVEVEADTAFEHGRWRHLTRYRRLRLDRSS

Sequences:

>Translated_318_residues
MPTTWEPMLAKPAATLPAVGGLLGGTVYEPKWDGYRAILERTGAGCRVWSRKGADLAAGFPEIVQAALERLEPGTVIDGE
LVVWRDGRLDFGALAPRLAYRGRRRSPADLPPASFLAFDVLVAGDVDLRTKPLRDRRAVLEQLAGSWQPPMQLTPQTADP
AEAQRWLTEYDAADVGVEGLVAKGAGQRYLPGQRGWVKFRIRNTREATVGAVIGRVDQPVRLILGLRDAAGTLRVAGATH
PLTPRESVELASVLVGTDDHPWPAELGTRQLGRFSREPVAITRVIPTVIVEVEADTAFEHGRWRHLTRYRRLRLDRSS
>Mature_317_residues
PTTWEPMLAKPAATLPAVGGLLGGTVYEPKWDGYRAILERTGAGCRVWSRKGADLAAGFPEIVQAALERLEPGTVIDGEL
VVWRDGRLDFGALAPRLAYRGRRRSPADLPPASFLAFDVLVAGDVDLRTKPLRDRRAVLEQLAGSWQPPMQLTPQTADPA
EAQRWLTEYDAADVGVEGLVAKGAGQRYLPGQRGWVKFRIRNTREATVGAVIGRVDQPVRLILGLRDAAGTLRVAGATHP
LTPRESVELASVLVGTDDHPWPAELGTRQLGRFSREPVAITRVIPTVIVEVEADTAFEHGRWRHLTRYRRLRLDRSS

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320038, Length=214, Percent_Identity=29.4392523364486, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 34950; Mature: 34819

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTTWEPMLAKPAATLPAVGGLLGGTVYEPKWDGYRAILERTGAGCRVWSRKGADLAAGF
CCCCCCCHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCHHCCC
PEIVQAALERLEPGTVIDGELVVWRDGRLDFGALAPRLAYRGRRRSPADLPPASFLAFDV
HHHHHHHHHHCCCCCEECCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LVAGDVDLRTKPLRDRRAVLEQLAGSWQPPMQLTPQTADPAEAQRWLTEYDAADVGVEGL
HEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCHHHE
VAKGAGQRYLPGQRGWVKFRIRNTREATVGAVIGRVDQPVRLILGLRDAAGTLRVAGATH
EECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHEEEECCCCCCEEEEECCCC
PLTPRESVELASVLVGTDDHPWPAELGTRQLGRFSREPVAITRVIPTVIVEVEADTAFEH
CCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCHHHEECCEEEEEEECCCCHHC
GRWRHLTRYRRLRLDRSS
CCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PTTWEPMLAKPAATLPAVGGLLGGTVYEPKWDGYRAILERTGAGCRVWSRKGADLAAGF
CCCCCCHHCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEECCCCCCHHCCC
PEIVQAALERLEPGTVIDGELVVWRDGRLDFGALAPRLAYRGRRRSPADLPPASFLAFDV
HHHHHHHHHHCCCCCEECCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
LVAGDVDLRTKPLRDRRAVLEQLAGSWQPPMQLTPQTADPAEAQRWLTEYDAADVGVEGL
HEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCHHHE
VAKGAGQRYLPGQRGWVKFRIRNTREATVGAVIGRVDQPVRLILGLRDAAGTLRVAGATH
EECCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCHHEEEECCCCCCEEEEECCCC
PLTPRESVELASVLVGTDDHPWPAELGTRQLGRFSREPVAITRVIPTVIVEVEADTAFEH
CCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCHHHEECCEEEEEEECCCCHHC
GRWRHLTRYRRLRLDRSS
CCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA