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The map label for this gene is pmtA [H]

Identifier: 119716424

GI number: 119716424

Start: 2344926

End: 2345567

Strand: Reverse

Name: pmtA [H]

Synonym: Noca_2195

Alternate gene names: 119716424

Gene position: 2345567-2344926 (Counterclockwise)

Preceding gene: 119716426

Following gene: 119716422

Centisome position: 47.04

GC content: 64.95

Gene sequence:

>642_bases
ATGACACAGAGTGCATACCAACCAGCGAGGTGGCAGCGCTACTGGGACAAGAAATCGCGTGGCTACGACCGCGAGATGGG
CATGTGGGACCGAGTGCTTTTCGGCAACTCGCGGCAGTGGGCCTGCTCGCAAGCCTCAGGTCACACCTTCGAGGTGGCAA
TCGGCACCGGCCTGAACCTCTCCTTCTATCCACCTGAAGTACGGCTGACCGGCATCGACCTAAGCGACGCGATGCTCGAG
ATCGCGCGCGGTCGCGCCGCGAACCAAGGCAGAGCGGCGGACCTGAGCCAGGGCAACGCGCACTCGCTGGCCTTCGAGGA
TGAGTCCTTCGACACCGTCGTGTGCACCTTCGGGCTCTGCGCCATCCCGGACCTCGACACAGCGCTCGACGAGATGGTCC
GGGTCCTGCGGCCAGGCGGCCAGCTGATCCTCGTCGACCACGTCCGGAGCACCTCAGCCATCGCTCGCGGGGTGCAGCGG
CTGCTGGAACTGGTCACGATGCCGTTGGGAGGAGAGCACTTCATGCGCCGCCCGCATGACGACGTGAAAGTACGGGGGCT
TCGGATCGAGCAAGTGCAGCGGTTCAAACTGGGTCTGGTCGAGCGACTCGTCGCGCGCAAGGCAGGAGAACCGTCGGCGT
GA

Upstream 100 bases:

>100_bases
GCACCGCCTTGTGGAGCCGAGCGCTCAGCCCGCCCAAAGCACTTCGTGCCGCTAGGAGGAAGTAGGGTGCTGAAGACATG
ACCGAAGCGGGTGCGGTGCG

Downstream 100 bases:

>100_bases
CGGCGACCGCAATACGAGTGAAGGACGCGCTCGCTACAAGCGTGGTACAAATGGCCGGAGATTATCGACGTTTGCGCAGG
TGAGAATGGGTCAGTCAGTC

Product: phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MTQSAYQPARWQRYWDKKSRGYDREMGMWDRVLFGNSRQWACSQASGHTFEVAIGTGLNLSFYPPEVRLTGIDLSDAMLE
IARGRAANQGRAADLSQGNAHSLAFEDESFDTVVCTFGLCAIPDLDTALDEMVRVLRPGGQLILVDHVRSTSAIARGVQR
LLELVTMPLGGEHFMRRPHDDVKVRGLRIEQVQRFKLGLVERLVARKAGEPSA

Sequences:

>Translated_213_residues
MTQSAYQPARWQRYWDKKSRGYDREMGMWDRVLFGNSRQWACSQASGHTFEVAIGTGLNLSFYPPEVRLTGIDLSDAMLE
IARGRAANQGRAADLSQGNAHSLAFEDESFDTVVCTFGLCAIPDLDTALDEMVRVLRPGGQLILVDHVRSTSAIARGVQR
LLELVTMPLGGEHFMRRPHDDVKVRGLRIEQVQRFKLGLVERLVARKAGEPSA
>Mature_212_residues
TQSAYQPARWQRYWDKKSRGYDREMGMWDRVLFGNSRQWACSQASGHTFEVAIGTGLNLSFYPPEVRLTGIDLSDAMLEI
ARGRAANQGRAADLSQGNAHSLAFEDESFDTVVCTFGLCAIPDLDTALDEMVRVLRPGGQLILVDHVRSTSAIARGVQRL
LELVTMPLGGEHFMRRPHDDVKVRGLRIEQVQRFKLGLVERLVARKAGEPSA

Specific function: This enzyme catalyzes three distinct methylation reactions for converting phosphatidylethanolamine to phosphatidylcholine [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI89145417, Length=137, Percent_Identity=35.036496350365, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI48994983, Length=132, Percent_Identity=34.8484848484849, Blast_Score=64, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6320522, Length=163, Percent_Identity=31.2883435582822, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.17 [H]

Molecular weight: Translated: 23802; Mature: 23671

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSAYQPARWQRYWDKKSRGYDREMGMWDRVLFGNSRQWACSQASGHTFEVAIGTGLNL
CCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEECCCCCCEEEEEECCCCCE
SFYPPEVRLTGIDLSDAMLEIARGRAANQGRAADLSQGNAHSLAFEDESFDTVVCTFGLC
EEECCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEHHCCC
AIPDLDTALDEMVRVLRPGGQLILVDHVRSTSAIARGVQRLLELVTMPLGGEHFMRRPHD
CCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
DVKVRGLRIEQVQRFKLGLVERLVARKAGEPSA
CCEEECEEHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQSAYQPARWQRYWDKKSRGYDREMGMWDRVLFGNSRQWACSQASGHTFEVAIGTGLNL
CCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCEEECCCCCCEEEEEECCCCCE
SFYPPEVRLTGIDLSDAMLEIARGRAANQGRAADLSQGNAHSLAFEDESFDTVVCTFGLC
EEECCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCEEEEHHCCC
AIPDLDTALDEMVRVLRPGGQLILVDHVRSTSAIARGVQRLLELVTMPLGGEHFMRRPHD
CCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCC
DVKVRGLRIEQVQRFKLGLVERLVARKAGEPSA
CCEEECEEHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8340421 [H]