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The map label for this gene is aceE [H]

Identifier: 119716336

GI number: 119716336

Start: 2248629

End: 2251307

Strand: Reverse

Name: aceE [H]

Synonym: Noca_2105

Alternate gene names: 119716336

Gene position: 2251307-2248629 (Counterclockwise)

Preceding gene: 119716337

Following gene: 119716335

Centisome position: 45.15

GC content: 74.09

Gene sequence:

>2679_bases
GTGACCACTGCGAACCTCCCCCACGACCCGATCGACTGGCACGACGAGCGCGCGGAGTGGCTCGACTCGGTCAGCGGCCT
GGTCCGCACCCACGGACCGCACGCCGCGAGCCTGCTCCTCCGCGACGTGGCCACCCACGCCGGCCGGCTCGGGGTCGCGA
CCGGGCCGCGTACGCCGTACCTCAACACGATCCCGACCCAGGAGTGGGCCGCCTATCCCGGCGACCTCGCCCTCGAGGAG
CGGATCGACGCCTACCTGCGGTGGAACGCGATGGCGATGGTGGTCCGGGCCAACAAGCGCCACGCCGGCCTCGGCGGGCA
CCTGTCGACCTACGCGTCCACGCTGACCCTGTGGGAGGTCGGCTTCCAGCACTTCTTCCGCGGCCGCGGCTCGGCGGGCG
AGGCCGTCGTCCCCGGAGACCAGGTGTTCTTCCAGGGCCACGCCAGCCCGGGCATCTACGCCCGGGCCTTCCTCGAGGGC
CGGCTGAGCGCCGAGCAGCTCGACCACTTCCGGCGCGAGGTAGCCGGCGCGGGGCAGGGCCTCCCGTCGTACCCGCACCC
CCGGAGCATGGCCGGCTTCTGGGAGTTCCCGACCGTGAGCCTCGGCATCGGCCCGCTGCACGCCGTCTACCAGGCCCGAT
TCAACCGCTACCTCGCCGCGCGCGGCCTCGCCGACACGGCGGCCGCCCGGGTGTGGTGCTTCGTCGGCGACGGCGAGATC
GACGAGCCCGAGACGCTGGCCGCGATCCGGCTGGCCGCCCGCGAGCACCTGGACAACATCGTCTTCGTCGTCAACGGCAA
CCTCCAGCGCCTCGACGGGCCGGTCCGCGGCAACAGTCGCGTCCTCGACGAGCTCGAGGGCATCTTCGCCGGCGCGGGTT
GGCACGTCCTCAAGGTGCTGTGGGGCAGCCGGTGGACCTCGCTCTTCGAGCGCCCCGGCGGCGAGGCCCTGCTCGACCGG
CTCGAGGCGATGAACGACGGGGACCTGCAGCGGCTGGCGATCCTCGAGCCCGCCGAGCTGCGCGCGACCCTGTTCGGCGG
CGGCGACGCCGCGCTGGAGGCGCTCGGCGCGACGCTCTCCGATGCCGACCTCGCCGGGCTGCGGCGCGGCGGGCACGACC
CGCGAGCCGTCTACGCTGCGTACGCCGAGGCCGTCGCGCACCGGGGCGAGCCCACCGTGGTGCTGGCGCAGACGATCAAG
GGCTACGCGCTCGGCCCGAACTTCGAGGGCCGCAACGCCACTCACCAGATGAAGAAGATGACGCCGGACCAGCTGCGCAT
CTTCCGCGACATCCTCCGGGTGCCGGTGACCGACGAGGAGCTGGCCGACGGGCTGCCGCCGTACCTGCCGCTGCCCGAGG
GCTCGCCGGAGCTGGAGTACCTCCACGCCCACCGGCGCACGCTCGGCGGCGCGCTCCCCCGCCGGCCGCTGCGCCCCGCC
GTCCTGGCCGCCCAGCCGGCCGACGCGCCCTTCACCCAGTTCGACGCCGGGTCCGGCAAGCGCACCGTGTCGACCACGGT
CGCCTACACCCGGCTGCTGCACTCGCTGATGCGCGACCCCGAGGTCGGGCGGCGAATCGTGCCGATCGTCCCGGACGAGG
GCCGCACCTTCGGCTACGAGCCGCTGTACAGCGAGTTCGGCATCTACGCGCCCGACGGGCAGCAGTACACGCCGGTCGAC
GCCGGCCTGCCGCTGTCCTACCGGGAGAGTGCGGACGGGCAGGTGCTGCAGGAGGGGATCACCGAGGCCGGCGGGCTCGC
CGAGCTGACGGCGGCGGCCACGGCCGGGCACACCTGGGACACCGCGGTCGTCCCGTTCTTCACCTACTACTCGATGTTCG
GCTTCCAGCGCGTCGGCGACCTGATCTGGGCCCTCGCCGACGCCCGGGGCCGCGGGTTCCTGGTCGGCGCGACGGCCGGT
CGTACGACGCTCGCCGGCGAGGGCCTGCAGCACACCGACGGCTCCTCGCAGCTGGCCGCGCTCGCCGTCCCGAGCTGCCA
CGCCTACGACCCGGCCTTCGCCTACGAGACCGCCACCATCGTCCGCGACGGGATCCGGCGGATGTACGACGCCGGCGAGG
AGTCCTTCTACTACCTGACCGTCTACAACGAGGACTACGTCCAGCCGGTCAAGCCGGTCGACTCCGGTGTCCGCAGCGTC
AGCGTGGACGAGGCGATCGTCGCCGGCCTGTACCGGGTCGACGCGACCGAGGGCAATCGGCTCCCCCAGGTCCGCCTCCT
GGCCTCCGGGCCGGCCGTCCGCACCGCGCAGCAGGCGGCCGCGGACCTGGCCGCGCGTGACGGCGTCACCGCCGAGGTGT
GGTCGGTGACCAGCTGGAAGGCGCTGCGCGACGACGCGCTCGAGACCGAGCGCTGGAACCGCGAGCACCCCCACGAGCCG
GCCCGCGTCAGCTACCTGCGCCGTGCCCTCGGCGACCTGCCGGTGCCGGTGGTCGCCGTGAGCGACTACGTGTCCGCGTT
GCCGGACCAGATCGCGCGCTTCGTCGACGCCCCCTTCGTGAGCCTCGGCACCGACGGCTACGGCCTCTCCGACACGCGCG
AGGAGCTCCGCGCCCACTTCGGTGTCGACGCGGAGGGGATCCGCGCGACGGCTGCCGGGGTCGCCGACCGGCCGGCGACC
CACCGCGCGGCCCGCCCCGACGAGGGCCTGGTGGCCTGA

Upstream 100 bases:

>100_bases
TCGTGACCCCGCACCTGTGCGTCGCCCGGCTGGAGCCACGAGCTTCGGCGTAGACCCGGGGGTCTTTGTTTTTAATGTGA
TCTCGCGGGATAATCGGACC

Downstream 100 bases:

>100_bases
GCTGCGGCACCGCACCGGTGTCGTTCGAACCGACCGAAGGAGACCGATCAAACCGATGATTGCCGAACGCACAGCCACGA
CCACCTGGCAGGGCGGCCTC

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 892; Mature: 891

Protein sequence:

>892_residues
MTTANLPHDPIDWHDERAEWLDSVSGLVRTHGPHAASLLLRDVATHAGRLGVATGPRTPYLNTIPTQEWAAYPGDLALEE
RIDAYLRWNAMAMVVRANKRHAGLGGHLSTYASTLTLWEVGFQHFFRGRGSAGEAVVPGDQVFFQGHASPGIYARAFLEG
RLSAEQLDHFRREVAGAGQGLPSYPHPRSMAGFWEFPTVSLGIGPLHAVYQARFNRYLAARGLADTAAARVWCFVGDGEI
DEPETLAAIRLAAREHLDNIVFVVNGNLQRLDGPVRGNSRVLDELEGIFAGAGWHVLKVLWGSRWTSLFERPGGEALLDR
LEAMNDGDLQRLAILEPAELRATLFGGGDAALEALGATLSDADLAGLRRGGHDPRAVYAAYAEAVAHRGEPTVVLAQTIK
GYALGPNFEGRNATHQMKKMTPDQLRIFRDILRVPVTDEELADGLPPYLPLPEGSPELEYLHAHRRTLGGALPRRPLRPA
VLAAQPADAPFTQFDAGSGKRTVSTTVAYTRLLHSLMRDPEVGRRIVPIVPDEGRTFGYEPLYSEFGIYAPDGQQYTPVD
AGLPLSYRESADGQVLQEGITEAGGLAELTAAATAGHTWDTAVVPFFTYYSMFGFQRVGDLIWALADARGRGFLVGATAG
RTTLAGEGLQHTDGSSQLAALAVPSCHAYDPAFAYETATIVRDGIRRMYDAGEESFYYLTVYNEDYVQPVKPVDSGVRSV
SVDEAIVAGLYRVDATEGNRLPQVRLLASGPAVRTAQQAAADLAARDGVTAEVWSVTSWKALRDDALETERWNREHPHEP
ARVSYLRRALGDLPVPVVAVSDYVSALPDQIARFVDAPFVSLGTDGYGLSDTREELRAHFGVDAEGIRATAAGVADRPAT
HRAARPDEGLVA

Sequences:

>Translated_892_residues
MTTANLPHDPIDWHDERAEWLDSVSGLVRTHGPHAASLLLRDVATHAGRLGVATGPRTPYLNTIPTQEWAAYPGDLALEE
RIDAYLRWNAMAMVVRANKRHAGLGGHLSTYASTLTLWEVGFQHFFRGRGSAGEAVVPGDQVFFQGHASPGIYARAFLEG
RLSAEQLDHFRREVAGAGQGLPSYPHPRSMAGFWEFPTVSLGIGPLHAVYQARFNRYLAARGLADTAAARVWCFVGDGEI
DEPETLAAIRLAAREHLDNIVFVVNGNLQRLDGPVRGNSRVLDELEGIFAGAGWHVLKVLWGSRWTSLFERPGGEALLDR
LEAMNDGDLQRLAILEPAELRATLFGGGDAALEALGATLSDADLAGLRRGGHDPRAVYAAYAEAVAHRGEPTVVLAQTIK
GYALGPNFEGRNATHQMKKMTPDQLRIFRDILRVPVTDEELADGLPPYLPLPEGSPELEYLHAHRRTLGGALPRRPLRPA
VLAAQPADAPFTQFDAGSGKRTVSTTVAYTRLLHSLMRDPEVGRRIVPIVPDEGRTFGYEPLYSEFGIYAPDGQQYTPVD
AGLPLSYRESADGQVLQEGITEAGGLAELTAAATAGHTWDTAVVPFFTYYSMFGFQRVGDLIWALADARGRGFLVGATAG
RTTLAGEGLQHTDGSSQLAALAVPSCHAYDPAFAYETATIVRDGIRRMYDAGEESFYYLTVYNEDYVQPVKPVDSGVRSV
SVDEAIVAGLYRVDATEGNRLPQVRLLASGPAVRTAQQAAADLAARDGVTAEVWSVTSWKALRDDALETERWNREHPHEP
ARVSYLRRALGDLPVPVVAVSDYVSALPDQIARFVDAPFVSLGTDGYGLSDTREELRAHFGVDAEGIRATAAGVADRPAT
HRAARPDEGLVA
>Mature_891_residues
TTANLPHDPIDWHDERAEWLDSVSGLVRTHGPHAASLLLRDVATHAGRLGVATGPRTPYLNTIPTQEWAAYPGDLALEER
IDAYLRWNAMAMVVRANKRHAGLGGHLSTYASTLTLWEVGFQHFFRGRGSAGEAVVPGDQVFFQGHASPGIYARAFLEGR
LSAEQLDHFRREVAGAGQGLPSYPHPRSMAGFWEFPTVSLGIGPLHAVYQARFNRYLAARGLADTAAARVWCFVGDGEID
EPETLAAIRLAAREHLDNIVFVVNGNLQRLDGPVRGNSRVLDELEGIFAGAGWHVLKVLWGSRWTSLFERPGGEALLDRL
EAMNDGDLQRLAILEPAELRATLFGGGDAALEALGATLSDADLAGLRRGGHDPRAVYAAYAEAVAHRGEPTVVLAQTIKG
YALGPNFEGRNATHQMKKMTPDQLRIFRDILRVPVTDEELADGLPPYLPLPEGSPELEYLHAHRRTLGGALPRRPLRPAV
LAAQPADAPFTQFDAGSGKRTVSTTVAYTRLLHSLMRDPEVGRRIVPIVPDEGRTFGYEPLYSEFGIYAPDGQQYTPVDA
GLPLSYRESADGQVLQEGITEAGGLAELTAAATAGHTWDTAVVPFFTYYSMFGFQRVGDLIWALADARGRGFLVGATAGR
TTLAGEGLQHTDGSSQLAALAVPSCHAYDPAFAYETATIVRDGIRRMYDAGEESFYYLTVYNEDYVQPVKPVDSGVRSVS
VDEAIVAGLYRVDATEGNRLPQVRLLASGPAVRTAQQAAADLAARDGVTAEVWSVTSWKALRDDALETERWNREHPHEPA
RVSYLRRALGDLPVPVVAVSDYVSALPDQIARFVDAPFVSLGTDGYGLSDTREELRAHFGVDAEGIRATAAGVADRPATH
RAARPDEGLVA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=870, Percent_Identity=46.2068965517241, Blast_Score=780, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 96744; Mature: 96612

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTANLPHDPIDWHDERAEWLDSVSGLVRTHGPHAASLLLRDVATHAGRLGVATGPRTPY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
LNTIPTQEWAAYPGDLALEERIDAYLRWNAMAMVVRANKRHAGLGGHLSTYASTLTLWEV
CCCCCCHHHHCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
GFQHFFRGRGSAGEAVVPGDQVFFQGHASPGIYARAFLEGRLSAEQLDHFRREVAGAGQG
HHHHHHCCCCCCCCEECCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
LPSYPHPRSMAGFWEFPTVSLGIGPLHAVYQARFNRYLAARGLADTAAARVWCFVGDGEI
CCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEECCCCC
DEPETLAAIRLAAREHLDNIVFVVNGNLQRLDGPVRGNSRVLDELEGIFAGAGWHVLKVL
CCCHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
WGSRWTSLFERPGGEALLDRLEAMNDGDLQRLAILEPAELRATLFGGGDAALEALGATLS
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCCHHHEEEEECCCHHHHHHHCCCCC
DADLAGLRRGGHDPRAVYAAYAEAVAHRGEPTVVLAQTIKGYALGPNFEGRNATHQMKKM
CHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCCHHHHHHHC
TPDQLRIFRDILRVPVTDEELADGLPPYLPLPEGSPELEYLHAHRRTLGGALPRRPLRPA
CHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCH
VLAAQPADAPFTQFDAGSGKRTVSTTVAYTRLLHSLMRDPEVGRRIVPIVPDEGRTFGYE
HEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCEEEEEECCCCCCCCCC
PLYSEFGIYAPDGQQYTPVDAGLPLSYRESADGQVLQEGITEAGGLAELTAAATAGHTWD
CHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCC
TAVVPFFTYYSMFGFQRVGDLIWALADARGRGFLVGATAGRTTLAGEGLQHTDGSSQLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCCCCCCCEEE
LAVPSCHAYDPAFAYETATIVRDGIRRMYDAGEESFYYLTVYNEDYVQPVKPVDSGVRSV
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHCCHHC
SVDEAIVAGLYRVDATEGNRLPQVRLLASGPAVRTAQQAAADLAARDGVTAEVWSVTSWK
CHHHHHHHHHHEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCHHH
ALRDDALETERWNREHPHEPARVSYLRRALGDLPVPVVAVSDYVSALPDQIARFVDAPFV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
SLGTDGYGLSDTREELRAHFGVDAEGIRATAAGVADRPATHRAARPDEGLVA
EECCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTANLPHDPIDWHDERAEWLDSVSGLVRTHGPHAASLLLRDVATHAGRLGVATGPRTPY
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
LNTIPTQEWAAYPGDLALEERIDAYLRWNAMAMVVRANKRHAGLGGHLSTYASTLTLWEV
CCCCCCHHHHCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHH
GFQHFFRGRGSAGEAVVPGDQVFFQGHASPGIYARAFLEGRLSAEQLDHFRREVAGAGQG
HHHHHHCCCCCCCCEECCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
LPSYPHPRSMAGFWEFPTVSLGIGPLHAVYQARFNRYLAARGLADTAAARVWCFVGDGEI
CCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCHHHCCEEEEEEECCCCC
DEPETLAAIRLAAREHLDNIVFVVNGNLQRLDGPVRGNSRVLDELEGIFAGAGWHVLKVL
CCCHHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHH
WGSRWTSLFERPGGEALLDRLEAMNDGDLQRLAILEPAELRATLFGGGDAALEALGATLS
HHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEECCCHHHEEEEECCCHHHHHHHCCCCC
DADLAGLRRGGHDPRAVYAAYAEAVAHRGEPTVVLAQTIKGYALGPNFEGRNATHQMKKM
CHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCCCCCHHHHHHHC
TPDQLRIFRDILRVPVTDEELADGLPPYLPLPEGSPELEYLHAHRRTLGGALPRRPLRPA
CHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCH
VLAAQPADAPFTQFDAGSGKRTVSTTVAYTRLLHSLMRDPEVGRRIVPIVPDEGRTFGYE
HEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCEEEEEECCCCCCCCCC
PLYSEFGIYAPDGQQYTPVDAGLPLSYRESADGQVLQEGITEAGGLAELTAAATAGHTWD
CHHHHCCCCCCCCCEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCC
TAVVPFFTYYSMFGFQRVGDLIWALADARGRGFLVGATAGRTTLAGEGLQHTDGSSQLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCCCCCCCCCEEE
LAVPSCHAYDPAFAYETATIVRDGIRRMYDAGEESFYYLTVYNEDYVQPVKPVDSGVRSV
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHHHCCHHC
SVDEAIVAGLYRVDATEGNRLPQVRLLASGPAVRTAQQAAADLAARDGVTAEVWSVTSWK
CHHHHHHHHHHEEECCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEECCCHHH
ALRDDALETERWNREHPHEPARVSYLRRALGDLPVPVVAVSDYVSALPDQIARFVDAPFV
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCEE
SLGTDGYGLSDTREELRAHFGVDAEGIRATAAGVADRPATHRAARPDEGLVA
EECCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA