Click here to switch to the map view.

The map label for this gene is prpB [C]

Identifier: 119716266

GI number: 119716266

Start: 2179170

End: 2179937

Strand: Reverse

Name: prpB [C]

Synonym: Noca_2035

Alternate gene names: 119716266

Gene position: 2179937-2179170 (Counterclockwise)

Preceding gene: 119716267

Following gene: 119716265

Centisome position: 43.72

GC content: 75.39

Gene sequence:

>768_bases
ATGTCGTTCCGGGCCCTGCACCACGCCGAGCTGCCCCTGCTGCTGCCGAACGCGTGGGACGTGCCGTCCGCGATCGCGTT
CGTCGAGGCCGGCTTCCCCGCGGTGGGGACGACCAGCTTCGGGGTCGCGACCTCGGCCGGCCATCCGGACGGCGACGGCG
CCACCCGCGACGCCAACCGGGTGCTCGCGGAGCGGCTGGCGCGGCTGCCGGCGTACGTCTCGATCGACATCGAGGACGGC
TACTCCGAGGACCCCGAGGAGGTGGCGGCGTACGTCGCCGAACTCGGGTCGTACGGCGTGGCCGGCGTGAACATCGAGGA
CAGCCTCGCGGCCCGGCTCGTCGACCCGACCCGGCAGGCCGCCAAGCTGGCCGCGGTCAAGGAGCGCAGCCCGGACGTGT
TCGTCAACGCCCGGGTCGACACCTACTGGTTCGACCAGGACGCGACCGTCCCCGCCACGGTCGAGCGCGCGCTGGCGTAC
GTCGCGGCCGGGGCCGACGGCGTCTTCGTCCCGGGCCTGACCGACCCCGCGGCGATCCGCGAGATCGCAGCCGCCGTACC
GGCGCCGCTGAACCTGCTCGTCACCCCCGGCCTGGCCCTGCGCGACCTCGCCGAGCTGGGCGTGCGCCGGGTCAGCACCG
GCTCGCTCCCCTATCGCGCCGCCGTCGACGCGGCCGTCCGGGCCGCGACCGCGGTCCGCGACGGGGAGCAGCCGCCGACG
GCGACGTCGTACGCCGAGGCGAACGAGCGCGTCCGCCGCTATCCTTGA

Upstream 100 bases:

>100_bases
CCGGATGCACAGCCCGGGCGGCGCCCGCCGGCACGTGGTCGGGCGGCACCGCGCCCTGCATCCCTGACAGCGGCACCCCT
GACAGTGGTTGACTCGGCCC

Downstream 100 bases:

>100_bases
GCCGCGGATGGGCTGGCCGGGCGACCGCGTGGAGGAGACTCCCCGAGGAAGGTCCGGGCTCCACAGGGCAGAGTGGTGGG
TAACACCCACCCGGGGCAAC

Product: hypothetical protein

Products: Pyruvate; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MSFRALHHAELPLLLPNAWDVPSAIAFVEAGFPAVGTTSFGVATSAGHPDGDGATRDANRVLAERLARLPAYVSIDIEDG
YSEDPEEVAAYVAELGSYGVAGVNIEDSLAARLVDPTRQAAKLAAVKERSPDVFVNARVDTYWFDQDATVPATVERALAY
VAAGADGVFVPGLTDPAAIREIAAAVPAPLNLLVTPGLALRDLAELGVRRVSTGSLPYRAAVDAAVRAATAVRDGEQPPT
ATSYAEANERVRRYP

Sequences:

>Translated_255_residues
MSFRALHHAELPLLLPNAWDVPSAIAFVEAGFPAVGTTSFGVATSAGHPDGDGATRDANRVLAERLARLPAYVSIDIEDG
YSEDPEEVAAYVAELGSYGVAGVNIEDSLAARLVDPTRQAAKLAAVKERSPDVFVNARVDTYWFDQDATVPATVERALAY
VAAGADGVFVPGLTDPAAIREIAAAVPAPLNLLVTPGLALRDLAELGVRRVSTGSLPYRAAVDAAVRAATAVRDGEQPPT
ATSYAEANERVRRYP
>Mature_254_residues
SFRALHHAELPLLLPNAWDVPSAIAFVEAGFPAVGTTSFGVATSAGHPDGDGATRDANRVLAERLARLPAYVSIDIEDGY
SEDPEEVAAYVAELGSYGVAGVNIEDSLAARLVDPTRQAAKLAAVKERSPDVFVNARVDTYWFDQDATVPATVERALAYV
AAGADGVFVPGLTDPAAIREIAAAVPAPLNLLVTPGLALRDLAELGVRRVSTGSLPYRAAVDAAVRAATAVRDGEQPPTA
TSYAEANERVRRYP

Specific function: Catalyzes The Formation Of Pyruvate And Succinate From 2-Methylisocitrate (By Similarity). [C]

COG id: COG2513

COG function: function code G; PEP phosphonomutase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR015813 [H]

Pfam domain/function: NA

EC number: 4.1.3.30 [C]

Molecular weight: Translated: 26792; Mature: 26661

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFRALHHAELPLLLPNAWDVPSAIAFVEAGFPAVGTTSFGVATSAGHPDGDGATRDANR
CCCCCCCCCCCCEECCCCCCCHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHHH
VLAERLARLPAYVSIDIEDGYSEDPEEVAAYVAELGSYGVAGVNIEDSLAARLVDPTRQA
HHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCHHHHH
AKLAAVKERSPDVFVNARVDTYWFDQDATVPATVERALAYVAAGADGVFVPGLTDPAAIR
HHHHHHHCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHH
EIAAAVPAPLNLLVTPGLALRDLAELGVRRVSTGSLPYRAAVDAAVRAATAVRDGEQPPT
HHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ATSYAEANERVRRYP
CCHHHHHHHHHHCCC
>Mature Secondary Structure 
SFRALHHAELPLLLPNAWDVPSAIAFVEAGFPAVGTTSFGVATSAGHPDGDGATRDANR
CCCCCCCCCCCEECCCCCCCHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCCCCHHHHH
VLAERLARLPAYVSIDIEDGYSEDPEEVAAYVAELGSYGVAGVNIEDSLAARLVDPTRQA
HHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCHHHHH
AKLAAVKERSPDVFVNARVDTYWFDQDATVPATVERALAYVAAGADGVFVPGLTDPAAIR
HHHHHHHCCCCCEEEEEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHH
EIAAAVPAPLNLLVTPGLALRDLAELGVRRVSTGSLPYRAAVDAAVRAATAVRDGEQPPT
HHHHHCCCCCEEEECCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
ATSYAEANERVRRYP
CCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: methylisocitrate [C]

Specific reaction: methylisocitrate <==> Pyruvate + Succinate [C]

General reaction: Elimination [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]