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The map label for this gene is glyQS [H]

Identifier: 119716172

GI number: 119716172

Start: 2070120

End: 2071535

Strand: Direct

Name: glyQS [H]

Synonym: Noca_1940

Alternate gene names: 119716172

Gene position: 2070120-2071535 (Clockwise)

Preceding gene: 119716171

Following gene: 119716173

Centisome position: 41.52

GC content: 67.87

Gene sequence:

>1416_bases
GTGGCCAAGCCCCCGCCGTCCACCGTCGACCACGTCGTCTCCCTCGCCAAGCGGCGGGGCTTCGTCTACCCGTGCGGCGA
GATCTACGGCGGCACCCGCTCCGCCTGGGACTACGGCCCGCTGGGCGTGGAGCTCAAGGAGAACATCAAGCGCCAGTGGT
GGAAGTCCATGGTCACCATGCGCGACGACATGGTCGGCCTCGACTCCAGCATCATCCTGCCGCGGCAGGTGTGGGAGGCC
AGCGGCCACGTCGACACGTTCATGGACCCGCTCACCGAGTGCCAGTCGTGCCACAAGCGGTTCCGCGCCGACCACCTCCA
GGAGGAGGTCGCGGAGAAGAAGTCCAAGTCCGAAGGGCACAGCGTCAACCCCGACGACGTCGATCTCGCGACGGTGGCCT
GCCCCAACTGCGGCACCCGCGGCGCGTGGACCGAGCCGCGGCAGTTCTCCGGCCTGCTCAAGACCCACCTGGGCGTCATC
GAGAACGAGGAGGGCCTGCACTACCTGCGGCCCGAGACCGCCCAGGGCATCTTCATCAACTTCGCGAACGTCGTGACCTC
GAGCCGGCACAAGCCGCCGTTCGGCATCGCCCAGATCGGCAAGAGCTTCCGCAACGAGATCACCCCCGGCAACTTCATCT
TCCGGACCCGCGAGTTCGAGCAGATGGAGATGGAGTTCTTCGTCAAGCCCGGCGAGGACAAGGAGTGGCACCAGTACTGG
ATCGACGAGCGCACCCGCTGGTACGTCGACCTCGGCATCGACCCCGACAACCTGCGCCACTTCGAGCACCCGCAGGAGAA
GCTCAGCCACTACTCCACGCGGACCGTCGACATCGAGTACCGGTTCCGGTTCGCCGGCTCGGAGTGGGGAGAGCTCGAGG
GCATCGCCAACCGCACCGACTTCGACCTGAGCACCCACTCCAAGCACTCCGGCCAGGACCTCTCCTACTTCGACCAGGCC
AACAACGAGCGCTACGTCCCCTACGTCATCGAGCCGGCCGCCGGCCTGTCCCGCAGCCTGATGACCTTCCTCGTCGACGC
CTACCAGGAGGACGAGGCGCCGAACACCAAGGGCGGCGTCGACAAGCGCACCGTGCTGCGCCTGGACCCGCGGCTCGCGC
CGGTCAAGGTGGCGGTGCTGCCGCTCTCTCGCAACGCGGACCTCTCGCCGAAGGCCAAGGACCTCGCCATGGAGCTGCGC
CGGGCCGGGTGGCACGTCGACTTCGACGACTCCGGCGCGATCGGCCGCCGCTACCGCCGCCAGGACGAGATCGGTACGCC
GTACTGCGTGACCGTCGACTTCGAGACGCTCGACGACCAGGCGGTCACCGTCCGCGAGCGCGACAGCATGCAGCAGGAGC
GGATCGGCCTGGACCGGATCAGCGCGTACTTCGCCGAGCGTCTGATCGGCTGCTGA

Upstream 100 bases:

>100_bases
CACCACCCTCAACGTCGCCTCGACCCGGTCGTTAGGCTGAGCCCTTCCGATCACCCACTCTGACCGGCAGCCAGCCGGCC
AAGTCATCAGGAGCGCCACC

Downstream 100 bases:

>100_bases
CCGCTCGGCATGCACAATGACCGAATGATCCGGCTCACCACACTGCTCGGGGCCGCCGTCGCGGGCGCGCTCGCTCTCGG
CGGCTGCTCGGGATCCGACG

Product: glycyl-tRNA synthetase

Products: NA

Alternate protein names: Glycine--tRNA ligase; GlyRS [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MAKPPPSTVDHVVSLAKRRGFVYPCGEIYGGTRSAWDYGPLGVELKENIKRQWWKSMVTMRDDMVGLDSSIILPRQVWEA
SGHVDTFMDPLTECQSCHKRFRADHLQEEVAEKKSKSEGHSVNPDDVDLATVACPNCGTRGAWTEPRQFSGLLKTHLGVI
ENEEGLHYLRPETAQGIFINFANVVTSSRHKPPFGIAQIGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGEDKEWHQYW
IDERTRWYVDLGIDPDNLRHFEHPQEKLSHYSTRTVDIEYRFRFAGSEWGELEGIANRTDFDLSTHSKHSGQDLSYFDQA
NNERYVPYVIEPAAGLSRSLMTFLVDAYQEDEAPNTKGGVDKRTVLRLDPRLAPVKVAVLPLSRNADLSPKAKDLAMELR
RAGWHVDFDDSGAIGRRYRRQDEIGTPYCVTVDFETLDDQAVTVRERDSMQQERIGLDRISAYFAERLIGC

Sequences:

>Translated_471_residues
MAKPPPSTVDHVVSLAKRRGFVYPCGEIYGGTRSAWDYGPLGVELKENIKRQWWKSMVTMRDDMVGLDSSIILPRQVWEA
SGHVDTFMDPLTECQSCHKRFRADHLQEEVAEKKSKSEGHSVNPDDVDLATVACPNCGTRGAWTEPRQFSGLLKTHLGVI
ENEEGLHYLRPETAQGIFINFANVVTSSRHKPPFGIAQIGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGEDKEWHQYW
IDERTRWYVDLGIDPDNLRHFEHPQEKLSHYSTRTVDIEYRFRFAGSEWGELEGIANRTDFDLSTHSKHSGQDLSYFDQA
NNERYVPYVIEPAAGLSRSLMTFLVDAYQEDEAPNTKGGVDKRTVLRLDPRLAPVKVAVLPLSRNADLSPKAKDLAMELR
RAGWHVDFDDSGAIGRRYRRQDEIGTPYCVTVDFETLDDQAVTVRERDSMQQERIGLDRISAYFAERLIGC
>Mature_470_residues
AKPPPSTVDHVVSLAKRRGFVYPCGEIYGGTRSAWDYGPLGVELKENIKRQWWKSMVTMRDDMVGLDSSIILPRQVWEAS
GHVDTFMDPLTECQSCHKRFRADHLQEEVAEKKSKSEGHSVNPDDVDLATVACPNCGTRGAWTEPRQFSGLLKTHLGVIE
NEEGLHYLRPETAQGIFINFANVVTSSRHKPPFGIAQIGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGEDKEWHQYWI
DERTRWYVDLGIDPDNLRHFEHPQEKLSHYSTRTVDIEYRFRFAGSEWGELEGIANRTDFDLSTHSKHSGQDLSYFDQAN
NERYVPYVIEPAAGLSRSLMTFLVDAYQEDEAPNTKGGVDKRTVLRLDPRLAPVKVAVLPLSRNADLSPKAKDLAMELRR
AGWHVDFDDSGAIGRRYRRQDEIGTPYCVTVDFETLDDQAVTVRERDSMQQERIGLDRISAYFAERLIGC

Specific function: Catalyzes the attachment of glycine to tRNA(Gly) [H]

COG id: COG0423

COG function: function code J; Glycyl-tRNA synthetase (class II)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI116805340, Length=356, Percent_Identity=32.0224719101124, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI70887790, Length=445, Percent_Identity=22.6966292134831, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI32564541, Length=361, Percent_Identity=30.1939058171745, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI17554996, Length=361, Percent_Identity=30.1939058171745, Blast_Score=144, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6325338, Length=370, Percent_Identity=29.7297297297297, Blast_Score=154, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6319597, Length=411, Percent_Identity=26.2773722627737, Blast_Score=134, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21357965, Length=360, Percent_Identity=30.2777777777778, Blast_Score=159, Evalue=6e-39,
Organism=Drosophila melanogaster, GI24664462, Length=360, Percent_Identity=30.2777777777778, Blast_Score=158, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR022961
- InterPro:   IPR002315 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF00587 tRNA-synt_2b [H]

EC number: =6.1.1.14 [H]

Molecular weight: Translated: 53973; Mature: 53842

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKPPPSTVDHVVSLAKRRGFVYPCGEIYGGTRSAWDYGPLGVELKENIKRQWWKSMVTM
CCCCCCCHHHHHHHHHHHCCCEEECHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RDDMVGLDSSIILPRQVWEASGHVDTFMDPLTECQSCHKRFRADHLQEEVAEKKSKSEGH
HHHHHCCCCCEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVNPDDVDLATVACPNCGTRGAWTEPRQFSGLLKTHLGVIENEEGLHYLRPETAQGIFIN
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCEECCCCCEEECCCCCCEEEEE
FANVVTSSRHKPPFGIAQIGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGEDKEWHQYW
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHCCEEEEECCCCCCHHHHHH
IDERTRWYVDLGIDPDNLRHFEHPQEKLSHYSTRTVDIEYRFRFAGSEWGELEGIANRTD
HCCCCEEEEEECCCHHHCHHCCCHHHHHHHCCCEEEEEEEEEEECCCCCCHHCCCCCCCC
FDLSTHSKHSGQDLSYFDQANNERYVPYVIEPAAGLSRSLMTFLVDAYQEDEAPNTKGGV
CCCCCCCCCCCCCCHHHHHCCCCEECCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
DKRTVLRLDPRLAPVKVAVLPLSRNADLSPKAKDLAMELRRAGWHVDFDDSGAIGRRYRR
CCCEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHH
QDEIGTPYCVTVDFETLDDQAVTVRERDSMQQERIGLDRISAYFAERLIGC
HHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKPPPSTVDHVVSLAKRRGFVYPCGEIYGGTRSAWDYGPLGVELKENIKRQWWKSMVTM
CCCCCCHHHHHHHHHHHCCCEEECHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RDDMVGLDSSIILPRQVWEASGHVDTFMDPLTECQSCHKRFRADHLQEEVAEKKSKSEGH
HHHHHCCCCCEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SVNPDDVDLATVACPNCGTRGAWTEPRQFSGLLKTHLGVIENEEGLHYLRPETAQGIFIN
CCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCEECCCCCEEECCCCCCEEEEE
FANVVTSSRHKPPFGIAQIGKSFRNEITPGNFIFRTREFEQMEMEFFVKPGEDKEWHQYW
HHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCHHHHCCEEEEECCCCCCHHHHHH
IDERTRWYVDLGIDPDNLRHFEHPQEKLSHYSTRTVDIEYRFRFAGSEWGELEGIANRTD
HCCCCEEEEEECCCHHHCHHCCCHHHHHHHCCCEEEEEEEEEEECCCCCCHHCCCCCCCC
FDLSTHSKHSGQDLSYFDQANNERYVPYVIEPAAGLSRSLMTFLVDAYQEDEAPNTKGGV
CCCCCCCCCCCCCCHHHHHCCCCEECCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
DKRTVLRLDPRLAPVKVAVLPLSRNADLSPKAKDLAMELRRAGWHVDFDDSGAIGRRYRR
CCCEEEEECCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEECCCCCCCHHHHHHH
QDEIGTPYCVTVDFETLDDQAVTVRERDSMQQERIGLDRISAYFAERLIGC
HHCCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA