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The map label for this gene is paaG [C]

Identifier: 119716089

GI number: 119716089

Start: 1980883

End: 1981749

Strand: Direct

Name: paaG [C]

Synonym: Noca_1856

Alternate gene names: 119716089

Gene position: 1980883-1981749 (Clockwise)

Preceding gene: 119716088

Following gene: 119716090

Centisome position: 39.73

GC content: 72.66

Gene sequence:

>867_bases
ATGCAGTTCGAGACCCTGGCCTGGGACGTCGACGAGCACGGCGTCCTGACGCTGACCCTCTCCCGACCCGAGCAGCTCAA
CGCGTTCTCCCTCACCATGGCGGACGAGCTCGAGGCGGCGTTCCGTCTGGTCCGGACCGCCGCCCAGGTCCGGGCGGTCG
TCGTGACCGGCCACGGGCGCGCGTTCTGCGCCGGCATGGACCTCTCCGCAGAGGGCAACGTGTTCGGGCTCGACGAGGCA
GCGGCCCCGACCGTCGCGGACCTGCGCGACCGACTGACCGCGCCGCCGTTCCAGGACGGGGTCCGGGACACCGGCGGCAA
GGTCGCGCTCGCGATCCACGAGTGCGACAAGCCGGTGATCGCTGCCATCAACGGGGCGGCCGTCGGCGTCGGTGCGACCA
TGACGCTGGCGATGGACATCCGGATGGCCTCGACCGCGGCGCGGATCGGCTTCGTCTTCGGGCGCCTGGGCATCGTGCCC
GAGGCCACCTCGTCGTACTTCCTGCCCCGCATCGTCGGTCTCCAGAAGGCGCTCGAGCTGGTCTACGCCGCCGACATCCT
CAGTGCGTCCGACGCGCTGGACCTCGGGCTGCTGCGGTCGGTCCACGAGCCGGAGGACCTGCTCCCGGCGGCCCGCGAGC
TGGCCCGCTCGTTCGTGGAGGACCGGTCCGTGCCGGCTCTGGCGATGACCCGCCGGCTCATGTGCAGCGGCGCCGCTGCC
GCGCACCCGATCGAGGCGCACCGCCGCGACAGCCTCGCGATGTGGCACGCCTCCGTCGGCGACGGTCGCGAGGGGGTCCG
GGCCTTCCTCGAGAAGCGGCCGCCCGTGTTCACCGGCACGATCGACGACGTCCCGGACCTGGGATGA

Upstream 100 bases:

>100_bases
AGCAGGTTGCCGCACACCCTCGCCGCCCGGTGACCGACCCGGGTCGCGCCCGGAGCGCCCGCACCGCATCCCCTTCCCCT
CCTCAGAGAGTGAGCACCTC

Downstream 100 bases:

>100_bases
CGCGTCCGACGGCGCGGTCTGGGAACGTCCGAGGTCCCGGACGTACCGCCGCTCGGTCGCCTGCTTGACCCAGTCGGCCC
GCTCCCCGATACTTCTTTCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 288; Mature: 288

Protein sequence:

>288_residues
MQFETLAWDVDEHGVLTLTLSRPEQLNAFSLTMADELEAAFRLVRTAAQVRAVVVTGHGRAFCAGMDLSAEGNVFGLDEA
AAPTVADLRDRLTAPPFQDGVRDTGGKVALAIHECDKPVIAAINGAAVGVGATMTLAMDIRMASTAARIGFVFGRLGIVP
EATSSYFLPRIVGLQKALELVYAADILSASDALDLGLLRSVHEPEDLLPAARELARSFVEDRSVPALAMTRRLMCSGAAA
AHPIEAHRRDSLAMWHASVGDGREGVRAFLEKRPPVFTGTIDDVPDLG

Sequences:

>Translated_288_residues
MQFETLAWDVDEHGVLTLTLSRPEQLNAFSLTMADELEAAFRLVRTAAQVRAVVVTGHGRAFCAGMDLSAEGNVFGLDEA
AAPTVADLRDRLTAPPFQDGVRDTGGKVALAIHECDKPVIAAINGAAVGVGATMTLAMDIRMASTAARIGFVFGRLGIVP
EATSSYFLPRIVGLQKALELVYAADILSASDALDLGLLRSVHEPEDLLPAARELARSFVEDRSVPALAMTRRLMCSGAAA
AHPIEAHRRDSLAMWHASVGDGREGVRAFLEKRPPVFTGTIDDVPDLG
>Mature_288_residues
MQFETLAWDVDEHGVLTLTLSRPEQLNAFSLTMADELEAAFRLVRTAAQVRAVVVTGHGRAFCAGMDLSAEGNVFGLDEA
AAPTVADLRDRLTAPPFQDGVRDTGGKVALAIHECDKPVIAAINGAAVGVGATMTLAMDIRMASTAARIGFVFGRLGIVP
EATSSYFLPRIVGLQKALELVYAADILSASDALDLGLLRSVHEPEDLLPAARELARSFVEDRSVPALAMTRRLMCSGAAA
AHPIEAHRRDSLAMWHASVGDGREGVRAFLEKRPPVFTGTIDDVPDLG

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=262, Percent_Identity=28.2442748091603, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4502327, Length=280, Percent_Identity=28.2142857142857, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI31542718, Length=269, Percent_Identity=26.3940520446097, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI45643119, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI260275230, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI70995211, Length=209, Percent_Identity=28.7081339712919, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI260274832, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI157694516, Length=232, Percent_Identity=25.8620689655172, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI213417737, Length=232, Percent_Identity=25.8620689655172, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI68989263, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=7e-13,
Organism=Escherichia coli, GI1787660, Length=268, Percent_Identity=32.8358208955224, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1787659, Length=275, Percent_Identity=32.3636363636364, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788597, Length=279, Percent_Identity=25.089605734767, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI221142681, Length=270, Percent_Identity=30.3703703703704, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1790281, Length=217, Percent_Identity=27.1889400921659, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788682, Length=216, Percent_Identity=29.6296296296296, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082183, Length=270, Percent_Identity=23.7037037037037, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI17540714, Length=214, Percent_Identity=30.8411214953271, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17549921, Length=202, Percent_Identity=33.6633663366337, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17535521, Length=211, Percent_Identity=29.8578199052133, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17534483, Length=270, Percent_Identity=27.037037037037, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17554946, Length=271, Percent_Identity=26.5682656826568, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560910, Length=260, Percent_Identity=24.6153846153846, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536985, Length=208, Percent_Identity=26.4423076923077, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540306, Length=266, Percent_Identity=25.5639097744361, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25141363, Length=218, Percent_Identity=27.5229357798165, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653139, Length=284, Percent_Identity=29.9295774647887, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI20129971, Length=264, Percent_Identity=28.7878787878788, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24653477, Length=264, Percent_Identity=28.7878787878788, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24654903, Length=199, Percent_Identity=28.1407035175879, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI19920382, Length=211, Percent_Identity=28.9099526066351, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357171, Length=220, Percent_Identity=26.3636363636364, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 30642; Mature: 30642

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFETLAWDVDEHGVLTLTLSRPEQLNAFSLTMADELEAAFRLVRTAAQVRAVVVTGHGR
CCCCEEEEECCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHEEEEEEECCCC
AFCAGMDLSAEGNVFGLDEAAAPTVADLRDRLTAPPFQDGVRDTGGKVALAIHECDKPVI
EEEECCCCCCCCCEEECCCCCCCHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEECCCCEE
AAINGAAVGVGATMTLAMDIRMASTAARIGFVFGRLGIVPEATSSYFLPRIVGLQKALEL
EEECCCEECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VYAADILSASDALDLGLLRSVHEPEDLLPAARELARSFVEDRSVPALAMTRRLMCSGAAA
HHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
AHPIEAHRRDSLAMWHASVGDGREGVRAFLEKRPPVFTGTIDDVPDLG
CCCHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEECCCCCCCCCC
>Mature Secondary Structure
MQFETLAWDVDEHGVLTLTLSRPEQLNAFSLTMADELEAAFRLVRTAAQVRAVVVTGHGR
CCCCEEEEECCCCCEEEEEECCCCCCCEEEEHHHHHHHHHHHHHHHHHHEEEEEEECCCC
AFCAGMDLSAEGNVFGLDEAAAPTVADLRDRLTAPPFQDGVRDTGGKVALAIHECDKPVI
EEEECCCCCCCCCEEECCCCCCCHHHHHHHHCCCCCHHHHHCCCCCEEEEEEEECCCCEE
AAINGAAVGVGATMTLAMDIRMASTAARIGFVFGRLGIVPEATSSYFLPRIVGLQKALEL
EEECCCEECCCCEEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHH
VYAADILSASDALDLGLLRSVHEPEDLLPAARELARSFVEDRSVPALAMTRRLMCSGAAA
HHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
AHPIEAHRRDSLAMWHASVGDGREGVRAFLEKRPPVFTGTIDDVPDLG
CCCHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA