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The map label for this gene is stcD [H]

Identifier: 119716077

GI number: 119716077

Start: 1968476

End: 1970491

Strand: Direct

Name: stcD [H]

Synonym: Noca_1844

Alternate gene names: 119716077

Gene position: 1968476-1970491 (Clockwise)

Preceding gene: 119716076

Following gene: 119716078

Centisome position: 39.48

GC content: 72.87

Gene sequence:

>2016_bases
GTGAGCGCAGACCCACTCGCTCCGGGCGCCGCGGGCAACCTGTCCCGGCTTCTCGAGCCACTGCGGCTCGGCGGGCGGAC
CCTGCGCAACCGGATCATCGTGACCGCGCACGCGACGTACAACATCGACGCCGAGCACCTCCCCAACGAGGACGACGTCG
CGTACTTCGTGGAGCGGGCGCGCGGCGGCGCGGCGCTCGTCGCGATGGGCACCACCGCGGTGCACCCCAGCTCGCCGACG
CCATACGGCATCTACCACAACTTCGACGACCGGATCGTGCCGCGCTACGAGGCGCTCAGCGCCGCCGTGCACGAGCACGG
CGGGCTGATCGTCCCGCAGCTGGGCCACATGGGGGCGCGCACGGACGGTGAGGCGGGCCCGGTGTGGGCACCATCCCAGG
TGTCGCACCACCTGTGGGGGAGCGTCCCGTACGCGATGAGCCGCGCCGACGTCCGCACCGTGATGGAGGCCTACGCGTCC
GCCGCGAAGCGTGCGGTGCGCGGGGGGATGGACGGTGTCGAGCTCTCGGTCGGTCACGGGCAGATGATCAACCTGTTCCT
CTCCCCGCTGACCAACCAGCGCGAGGACGAGTACGGCGGATCGGACGAGGCGCGCTTCCGGTTCTGCCGCGAGGTGCTCG
AGGGCGTCCGGGAGGCCGTCGGCGACGCGCTCCTGCTGGTCCGGGTGAACGGATCCGACGAGGCGCCCGGATCCCTCGAC
CAGGACGCCTGGCTCGACATCGACCAGCGCATTGCCGAGTCCGGGCTCGTCGACGCCATCAACGTCTCGGCGAACTTCTA
CGGGTCCGTGATCCCCACGATGGCCGTCGCACGGGGCTGTTACCTGCACTACGCCCGCGCGGTGAAGCAACGGGTCGACC
TGCCGGTCGGCGCCGTCGGCCGGATCACCGACCCGACGATGGCGGCGCAGGCGCTGGAGGACGGCGACGCCGACTTCGTC
GGGATGACCCGCGCCCACATCGCCGACCCGCACCTGGTCCGCAAGATAGCCGAGGGCCGCACCGACGAGATCCGGCCGTG
CATCGGCTGCATCCAGATGTGCCAGGGCGAGCTCGGCCGCCACCGCAATGTGAAGTGCGTCTACAACGCGGTGACCGGTC
GGGAGCGCTTCCTGCGTGAGGTGGAGACCACGCCGGCCGCCGCGCGACGGCGCGTCGTCGTCGTCGGAGGGGGCCCGGCG
GGATTGGAGACAGCACGCGTCAGCGCGCTCCGCGGTCACGACGTGACCCTGTTCGACGAGCGAGCCGAGCTCGGCGGGGT
GGTCCGGGTCGCGGCGCGGACGGACGGCCGGGACGGCCTCATCGACGCGGTCGACTGGCTCGGCAACGAGGTCCGCCGGC
TCGGGGTGGACGTGCGGTTGCGGCGTACTGCGGAGGCCGCGGACGTCCTCGCGCTCAAGCCCGACGTCGTGGTGCTCGCC
ACCGGCGCCTCGGAGGCGCTGCCGCTGTGGGCCGAACGCGAGGACCGCCGGCTGCTCGGTGCCGCCGACGTCGTCTCCGG
ACGGCCCGCCCTCTCCGGCACGGTGGCCGTGGTCGACGAGACGGACCGCACCAGCGGCATGTCGGCGGCGCTGGCGGCCG
CCGAGCAGGGTTGCTCGGTGGTCCTCCTCACCGCACGCCCCGGCCCGGCCGAGCTCGTCGAGCGGGAGGTGCGCGACGAC
TTCCTGCAGCGCCTGGTCGCCGCCGGCGTCGAGATCCGCACGTCGACGCAGGTTCGCTCCTGGGACCGGGGCGCGGGCGT
CCTGCACTGCGGGGTCGGCGGACTCGCCGCACTGACCTATCGCGACGTCGACGATCACGGGCACGTGCTCGTCCGCGACG
TCCCCGATCTCGCCGTCGCCGCCGACTTCGTCGTCCACACCTGGACCGAGCCGCGGGCCGAGCTCTTCGAGGACCTGCCC
GACTCGGTCGACGTGCGCGCCGTCGGCGACGTGCTCAACCCCCATCGCATCGAGGGCGCGGTCCACGCTGCCTTCGAGCT
CGCAGCCAGCTTCTGA

Upstream 100 bases:

>100_bases
GCGCGATGCTCGGCGAGACGGGCGCCCAGGGTGTGCTGACCGGACTCGGCGACCCCACGTCGACGCTGCACGCCGTCCTG
GTGCCCGTGTGGGGGAGCAA

Downstream 100 bases:

>100_bases
TCCACCACCTGAGGAGAGAACCGATGTCCCTTCCACTCCGTCCCGCCGTTGCCGCCGGCGACTTCGTCGCCATCTCGGGC
CAGGTCGGCGTCGCCGATGG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: trans-transtetradehydroacyl-CoA; NADPH [C]

Alternate protein names: Stachydrine utilization protein stcD [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MSADPLAPGAAGNLSRLLEPLRLGGRTLRNRIIVTAHATYNIDAEHLPNEDDVAYFVERARGGAALVAMGTTAVHPSSPT
PYGIYHNFDDRIVPRYEALSAAVHEHGGLIVPQLGHMGARTDGEAGPVWAPSQVSHHLWGSVPYAMSRADVRTVMEAYAS
AAKRAVRGGMDGVELSVGHGQMINLFLSPLTNQREDEYGGSDEARFRFCREVLEGVREAVGDALLLVRVNGSDEAPGSLD
QDAWLDIDQRIAESGLVDAINVSANFYGSVIPTMAVARGCYLHYARAVKQRVDLPVGAVGRITDPTMAAQALEDGDADFV
GMTRAHIADPHLVRKIAEGRTDEIRPCIGCIQMCQGELGRHRNVKCVYNAVTGRERFLREVETTPAAARRRVVVVGGGPA
GLETARVSALRGHDVTLFDERAELGGVVRVAARTDGRDGLIDAVDWLGNEVRRLGVDVRLRRTAEAADVLALKPDVVVLA
TGASEALPLWAEREDRRLLGAADVVSGRPALSGTVAVVDETDRTSGMSAALAAAEQGCSVVLLTARPGPAELVEREVRDD
FLQRLVAAGVEIRTSTQVRSWDRGAGVLHCGVGGLAALTYRDVDDHGHVLVRDVPDLAVAADFVVHTWTEPRAELFEDLP
DSVDVRAVGDVLNPHRIEGAVHAAFELAASF

Sequences:

>Translated_671_residues
MSADPLAPGAAGNLSRLLEPLRLGGRTLRNRIIVTAHATYNIDAEHLPNEDDVAYFVERARGGAALVAMGTTAVHPSSPT
PYGIYHNFDDRIVPRYEALSAAVHEHGGLIVPQLGHMGARTDGEAGPVWAPSQVSHHLWGSVPYAMSRADVRTVMEAYAS
AAKRAVRGGMDGVELSVGHGQMINLFLSPLTNQREDEYGGSDEARFRFCREVLEGVREAVGDALLLVRVNGSDEAPGSLD
QDAWLDIDQRIAESGLVDAINVSANFYGSVIPTMAVARGCYLHYARAVKQRVDLPVGAVGRITDPTMAAQALEDGDADFV
GMTRAHIADPHLVRKIAEGRTDEIRPCIGCIQMCQGELGRHRNVKCVYNAVTGRERFLREVETTPAAARRRVVVVGGGPA
GLETARVSALRGHDVTLFDERAELGGVVRVAARTDGRDGLIDAVDWLGNEVRRLGVDVRLRRTAEAADVLALKPDVVVLA
TGASEALPLWAEREDRRLLGAADVVSGRPALSGTVAVVDETDRTSGMSAALAAAEQGCSVVLLTARPGPAELVEREVRDD
FLQRLVAAGVEIRTSTQVRSWDRGAGVLHCGVGGLAALTYRDVDDHGHVLVRDVPDLAVAADFVVHTWTEPRAELFEDLP
DSVDVRAVGDVLNPHRIEGAVHAAFELAASF
>Mature_670_residues
SADPLAPGAAGNLSRLLEPLRLGGRTLRNRIIVTAHATYNIDAEHLPNEDDVAYFVERARGGAALVAMGTTAVHPSSPTP
YGIYHNFDDRIVPRYEALSAAVHEHGGLIVPQLGHMGARTDGEAGPVWAPSQVSHHLWGSVPYAMSRADVRTVMEAYASA
AKRAVRGGMDGVELSVGHGQMINLFLSPLTNQREDEYGGSDEARFRFCREVLEGVREAVGDALLLVRVNGSDEAPGSLDQ
DAWLDIDQRIAESGLVDAINVSANFYGSVIPTMAVARGCYLHYARAVKQRVDLPVGAVGRITDPTMAAQALEDGDADFVG
MTRAHIADPHLVRKIAEGRTDEIRPCIGCIQMCQGELGRHRNVKCVYNAVTGRERFLREVETTPAAARRRVVVVGGGPAG
LETARVSALRGHDVTLFDERAELGGVVRVAARTDGRDGLIDAVDWLGNEVRRLGVDVRLRRTAEAADVLALKPDVVVLAT
GASEALPLWAEREDRRLLGAADVVSGRPALSGTVAVVDETDRTSGMSAALAAAEQGCSVVLLTARPGPAELVEREVRDDF
LQRLVAAGVEIRTSTQVRSWDRGAGVLHCGVGGLAALTYRDVDDHGHVLVRDVPDLAVAADFVVHTWTEPRAELFEDLPD
SVDVRAVGDVLNPHRIEGAVHAAFELAASF

Specific function: Possible NADH-dependent oxidase, functions as a demethylase that converts N-methylproline to proline [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=651, Percent_Identity=29.9539170506912, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI1787939, Length=357, Percent_Identity=25.7703081232493, Blast_Score=73, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17566914, Length=362, Percent_Identity=25.1381215469613, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=345, Percent_Identity=24.0579710144928, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17540738, Length=244, Percent_Identity=27.0491803278689, Blast_Score=73, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI72001454, Length=262, Percent_Identity=25.9541984732824, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17564188, Length=256, Percent_Identity=26.171875, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565138, Length=362, Percent_Identity=24.0331491712707, Blast_Score=70, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559804, Length=348, Percent_Identity=23.8505747126437, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321973, Length=247, Percent_Identity=26.7206477732794, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6325086, Length=229, Percent_Identity=26.6375545851528, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: 1.3.1.34 [C]

Molecular weight: Translated: 71909; Mature: 71778

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSADPLAPGAAGNLSRLLEPLRLGGRTLRNRIIVTAHATYNIDAEHLPNEDDVAYFVERA
CCCCCCCCCCCCCHHHHHHHHHHCCHHHHCEEEEEEEEEECCCHHHCCCCCHHHHHHHHC
RGGAALVAMGTTAVHPSSPTPYGIYHNFDDRIVPRYEALSAAVHEHGGLIVPQLGHMGAR
CCCEEEEEECCEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCC
TDGEAGPVWAPSQVSHHLWGSVPYAMSRADVRTVMEAYASAAKRAVRGGMDGVELSVGHG
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
QMINLFLSPLTNQREDEYGGSDEARFRFCREVLEGVREAVGDALLLVRVNGSDEAPGSLD
CEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
QDAWLDIDQRIAESGLVDAINVSANFYGSVIPTMAVARGCYLHYARAVKQRVDLPVGAVG
CHHHCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RITDPTMAAQALEDGDADFVGMTRAHIADPHLVRKIAEGRTDEIRPCIGCIQMCQGELGR
CCCCHHHHHHHHHCCCCCEEECHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
HRNVKCVYNAVTGRERFLREVETTPAAARRRVVVVGGGPAGLETARVSALRGHDVTLFDE
CCCCEEEEECHHHHHHHHHHHHCCCHHHCCEEEEECCCCCCCHHHHHHHHCCCCEEEECC
RAELGGVVRVAARTDGRDGLIDAVDWLGNEVRRLGVDVRLRRTAEAADVLALKPDVVVLA
HHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECHHCHHHEEEECCCEEEEE
TGASEALPLWAEREDRRLLGAADVVSGRPALSGTVAVVDETDRTSGMSAALAAAEQGCSV
CCCCCCCCCCCCCCCCHHCCHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEE
VLLTARPGPAELVEREVRDDFLQRLVAAGVEIRTSTQVRSWDRGAGVLHCGVGGLAALTY
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCCCCCCEEEECCCCEEEEEE
RDVDDHGHVLVRDVPDLAVAADFVVHTWTEPRAELFEDLPDSVDVRAVGDVLNPHRIEGA
ECCCCCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHCCCCCHHHHHH
VHAAFELAASF
HHHHHHHHHCC
>Mature Secondary Structure 
SADPLAPGAAGNLSRLLEPLRLGGRTLRNRIIVTAHATYNIDAEHLPNEDDVAYFVERA
CCCCCCCCCCCCHHHHHHHHHHCCHHHHCEEEEEEEEEECCCHHHCCCCCHHHHHHHHC
RGGAALVAMGTTAVHPSSPTPYGIYHNFDDRIVPRYEALSAAVHEHGGLIVPQLGHMGAR
CCCEEEEEECCEEECCCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCCC
TDGEAGPVWAPSQVSHHLWGSVPYAMSRADVRTVMEAYASAAKRAVRGGMDGVELSVGHG
CCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCC
QMINLFLSPLTNQREDEYGGSDEARFRFCREVLEGVREAVGDALLLVRVNGSDEAPGSLD
CEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCC
QDAWLDIDQRIAESGLVDAINVSANFYGSVIPTMAVARGCYLHYARAVKQRVDLPVGAVG
CHHHCCHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RITDPTMAAQALEDGDADFVGMTRAHIADPHLVRKIAEGRTDEIRPCIGCIQMCQGELGR
CCCCHHHHHHHHHCCCCCEEECHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
HRNVKCVYNAVTGRERFLREVETTPAAARRRVVVVGGGPAGLETARVSALRGHDVTLFDE
CCCCEEEEECHHHHHHHHHHHHCCCHHHCCEEEEECCCCCCCHHHHHHHHCCCCEEEECC
RAELGGVVRVAARTDGRDGLIDAVDWLGNEVRRLGVDVRLRRTAEAADVLALKPDVVVLA
HHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECHHCHHHEEEECCCEEEEE
TGASEALPLWAEREDRRLLGAADVVSGRPALSGTVAVVDETDRTSGMSAALAAAEQGCSV
CCCCCCCCCCCCCCCCHHCCHHHHCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEE
VLLTARPGPAELVEREVRDDFLQRLVAAGVEIRTSTQVRSWDRGAGVLHCGVGGLAALTY
EEEECCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHCCCCCCCEEEECCCCEEEEEE
RDVDDHGHVLVRDVPDLAVAADFVVHTWTEPRAELFEDLPDSVDVRAVGDVLNPHRIEGA
ECCCCCCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHCCCCCHHHHHH
VHAAFELAASF
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: transDidehydroacyl-CoA; NADP+ [C]

Specific reaction: transDidehydroacyl-CoA + NADP+ =trans-transtetradehydroacyl-CoA + NADPH [C]

General reaction: Redox reaction [C]

Inhibitor: Iodoacetic acid; N-Ethyl maleimide [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9758825; 11481431 [H]