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The map label for this gene is yqeF [C]

Identifier: 119716031

GI number: 119716031

Start: 1909823

End: 1911013

Strand: Direct

Name: yqeF [C]

Synonym: Noca_1797

Alternate gene names: 119716031

Gene position: 1909823-1911013 (Clockwise)

Preceding gene: 119716026

Following gene: 119716032

Centisome position: 38.3

GC content: 70.95

Gene sequence:

>1191_bases
ATGTCCGGTTCTGTCATCGTCGCGGGGGCACGGACCCCCATCGGACGCCTGCTCGGCGGGCTCAAGGGGCTCTCCGCGGC
CGACCTCGGCGGCGTCGCCATCAAGGCCGCGCTCGAGAAGGCCGGCGTCACCGGCGACCAGGTCGAGTACGTGATCATGG
GTCACGTGATCCAGGCCGGGGCCGGCCAGATCACCGCCCGTCAGGCCTCGGTCAAGGGCGGCATCCCGATGAACGTTCCC
GCCATCACGATCAACAAGGTGTGCCTGTCCGGCATGAACGCGATCGCGCTCGCCGACCAGCTGATCCGGGCCGGCGAGCA
CGAGATCGTCGTCGCGGGCGGCATGGAGTCCATGACGCAGGCGCCGCACCTGCTCCCCAAGTCCCGTGAGGGCTTCAAGT
ACGGCGACACCGCCCTGGTCGACTCGATGGCCTACGACGCCCTCTACGACCAGTTCACCGACCAGCCGATGGGCACGCTG
ACCGAGGCCTGCAACACGGGGGCCCGCGAGCTGACCCGCGAGGAGCAGGACGCGTTCTCGGCGCGCTCCCACCAGCTCGC
CGCTGCCGCGTGGAAGAACGGCGTCTTCGACGACGAGGTGGTCCCGGTCGAGATCCCGCAGCGCAAGGGCGATCCGGTCG
TGATCGCGAACGACGAGGGGATCCGCGGCGACACCACGGCGGAGTCGCTCGGCAAGCTGCGCCCGGCGTTCAGCAAGGAC
GGCACGATCACCGCCGGCTCCTCCTCGCAGATCTCCGACGGCGCCTGCGCCGTGGTCGTGATGAGCAAGGCCAAGGCCGA
GGAGCTGGGCCTCACCTGGCTCGCCGAGATCGGCGCCTCCGGTCAGGTCGCGGGCCCGGACTCCAGCCTGCAGAGCCAGC
CGGCCAACGCGATCAAGAAGGCCGTCGCCAAGGAGGGCATCTCCGTGGCGGACCTGGACCTGGTCGAGCTGAACGAGGCC
TTCGCGGCCGTCGGGATCGTGTCCGCCCGCGAGCTCGGGATCCCCGAGGAGCAGGTCAACGTGAACGGTGGGGCGATCGC
GCTGGGTCACCCTGTCGGCATGTCGGGCGCCCGGATCGTGCTGCACCTCGCGCTCGAGCTCAAGCGCCGCGGTGGCGGGG
TCGGCGCGGCCGCCCTGTGCGGCGGCGGCGGGCAGGGCGACGCCCTGATCGTGCGTGTCCCGAAGAGCTGA

Upstream 100 bases:

>100_bases
ATGTGTCCCACGGGACCAAAGTCTCGGCCTCTCGCCCCTGCGATGACCCGTGGGTAAGGTCGGCCAGAGATACCCCTGTC
GTACTTCCTGGAGGCTCCCC

Downstream 100 bases:

>100_bases
CGACGCCGGCGCCGTCCCGGGCCTCGTCGAGCGCGCCCGCGCCGGCGAGGCCCGGGCGGTCGCCCGGCTGATCTCGCTCG
TCGAGGACGAGTCTCCGCTG

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSGSVIVAGARTPIGRLLGGLKGLSAADLGGVAIKAALEKAGVTGDQVEYVIMGHVIQAGAGQITARQASVKGGIPMNVP
AITINKVCLSGMNAIALADQLIRAGEHEIVVAGGMESMTQAPHLLPKSREGFKYGDTALVDSMAYDALYDQFTDQPMGTL
TEACNTGARELTREEQDAFSARSHQLAAAAWKNGVFDDEVVPVEIPQRKGDPVVIANDEGIRGDTTAESLGKLRPAFSKD
GTITAGSSSQISDGACAVVVMSKAKAEELGLTWLAEIGASGQVAGPDSSLQSQPANAIKKAVAKEGISVADLDLVELNEA
FAAVGIVSARELGIPEEQVNVNGGAIALGHPVGMSGARIVLHLALELKRRGGGVGAAALCGGGGQGDALIVRVPKS

Sequences:

>Translated_396_residues
MSGSVIVAGARTPIGRLLGGLKGLSAADLGGVAIKAALEKAGVTGDQVEYVIMGHVIQAGAGQITARQASVKGGIPMNVP
AITINKVCLSGMNAIALADQLIRAGEHEIVVAGGMESMTQAPHLLPKSREGFKYGDTALVDSMAYDALYDQFTDQPMGTL
TEACNTGARELTREEQDAFSARSHQLAAAAWKNGVFDDEVVPVEIPQRKGDPVVIANDEGIRGDTTAESLGKLRPAFSKD
GTITAGSSSQISDGACAVVVMSKAKAEELGLTWLAEIGASGQVAGPDSSLQSQPANAIKKAVAKEGISVADLDLVELNEA
FAAVGIVSARELGIPEEQVNVNGGAIALGHPVGMSGARIVLHLALELKRRGGGVGAAALCGGGGQGDALIVRVPKS
>Mature_395_residues
SGSVIVAGARTPIGRLLGGLKGLSAADLGGVAIKAALEKAGVTGDQVEYVIMGHVIQAGAGQITARQASVKGGIPMNVPA
ITINKVCLSGMNAIALADQLIRAGEHEIVVAGGMESMTQAPHLLPKSREGFKYGDTALVDSMAYDALYDQFTDQPMGTLT
EACNTGARELTREEQDAFSARSHQLAAAAWKNGVFDDEVVPVEIPQRKGDPVVIANDEGIRGDTTAESLGKLRPAFSKDG
TITAGSSSQISDGACAVVVMSKAKAEELGLTWLAEIGASGQVAGPDSSLQSQPANAIKKAVAKEGISVADLDLVELNEAF
AAVGIVSARELGIPEEQVNVNGGAIALGHPVGMSGARIVLHLALELKRRGGGVGAAALCGGGGQGDALIVRVPKS

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=391, Percent_Identity=45.7800511508951, Blast_Score=293, Evalue=3e-79,
Organism=Homo sapiens, GI167614485, Length=395, Percent_Identity=42.7848101265823, Blast_Score=271, Evalue=6e-73,
Organism=Homo sapiens, GI4557237, Length=390, Percent_Identity=40, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI4501853, Length=397, Percent_Identity=40.0503778337531, Blast_Score=237, Evalue=1e-62,
Organism=Homo sapiens, GI4504327, Length=433, Percent_Identity=31.8706697459584, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI194353979, Length=392, Percent_Identity=28.8265306122449, Blast_Score=131, Evalue=8e-31,
Organism=Escherichia coli, GI87082165, Length=394, Percent_Identity=47.2081218274112, Blast_Score=322, Evalue=3e-89,
Organism=Escherichia coli, GI1788554, Length=394, Percent_Identity=45.6852791878173, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI1787663, Length=400, Percent_Identity=38, Blast_Score=241, Evalue=4e-65,
Organism=Escherichia coli, GI48994986, Length=403, Percent_Identity=36.7245657568238, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1788683, Length=407, Percent_Identity=31.4496314496315, Blast_Score=175, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI133906874, Length=389, Percent_Identity=42.9305912596401, Blast_Score=273, Evalue=1e-73,
Organism=Caenorhabditis elegans, GI25147385, Length=391, Percent_Identity=38.3631713554987, Blast_Score=260, Evalue=9e-70,
Organism=Caenorhabditis elegans, GI17535921, Length=389, Percent_Identity=38.8174807197943, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17535917, Length=395, Percent_Identity=32.9113924050633, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17551802, Length=426, Percent_Identity=31.2206572769953, Blast_Score=174, Evalue=8e-44,
Organism=Saccharomyces cerevisiae, GI6325229, Length=401, Percent_Identity=41.1471321695761, Blast_Score=268, Evalue=9e-73,
Organism=Saccharomyces cerevisiae, GI6322031, Length=405, Percent_Identity=35.3086419753086, Blast_Score=197, Evalue=2e-51,
Organism=Drosophila melanogaster, GI24655093, Length=391, Percent_Identity=45.0127877237852, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24640423, Length=389, Percent_Identity=41.6452442159383, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI17648125, Length=392, Percent_Identity=38.0102040816327, Blast_Score=221, Evalue=8e-58,
Organism=Drosophila melanogaster, GI17137578, Length=428, Percent_Identity=31.3084112149533, Blast_Score=175, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40373; Mature: 40242

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGSVIVAGARTPIGRLLGGLKGLSAADLGGVAIKAALEKAGVTGDQVEYVIMGHVIQAG
CCCCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHHHCC
AGQITARQASVKGGIPMNVPAITINKVCLSGMNAIALADQLIRAGEHEIVVAGGMESMTQ
CCCEEEEHHHCCCCCCCCCCEEEHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHHHH
APHLLPKSREGFKYGDTALVDSMAYDALYDQFTDQPMGTLTEACNTGARELTREEQDAFS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHH
ARSHQLAAAAWKNGVFDDEVVPVEIPQRKGDPVVIANDEGIRGDTTAESLGKLRPAFSKD
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCC
GTITAGSSSQISDGACAVVVMSKAKAEELGLTWLAEIGASGQVAGPDSSLQSQPANAIKK
CCEECCCCCCCCCCCEEEEEEECCCHHHHCCHHHHHCCCCCCCCCCCCHHHCCCHHHHHH
AVAKEGISVADLDLVELNEAFAAVGIVSARELGIPEEQVNVNGGAIALGHPVGMSGARIV
HHHHCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCEEEECCCCCCCCHHHH
LHLALELKRRGGGVGAAALCGGGGQGDALIVRVPKS
HHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCC
>Mature Secondary Structure 
SGSVIVAGARTPIGRLLGGLKGLSAADLGGVAIKAALEKAGVTGDQVEYVIMGHVIQAG
CCCEEEEECCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEEHHHHCC
AGQITARQASVKGGIPMNVPAITINKVCLSGMNAIALADQLIRAGEHEIVVAGGMESMTQ
CCCEEEEHHHCCCCCCCCCCEEEHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHHHH
APHLLPKSREGFKYGDTALVDSMAYDALYDQFTDQPMGTLTEACNTGARELTREEQDAFS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHH
ARSHQLAAAAWKNGVFDDEVVPVEIPQRKGDPVVIANDEGIRGDTTAESLGKLRPAFSKD
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCHHHHHHHCCCCCCCC
GTITAGSSSQISDGACAVVVMSKAKAEELGLTWLAEIGASGQVAGPDSSLQSQPANAIKK
CCEECCCCCCCCCCCEEEEEEECCCHHHHCCHHHHHCCCCCCCCCCCCHHHCCCHHHHHH
AVAKEGISVADLDLVELNEAFAAVGIVSARELGIPEEQVNVNGGAIALGHPVGMSGARIV
HHHHCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCHHHEECCCCEEEECCCCCCCCHHHH
LHLALELKRRGGGVGAAALCGGGGQGDALIVRVPKS
HHHHHHHHHCCCCCCEEEEECCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA