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The map label for this gene is atpB

Identifier: 119715992

GI number: 119715992

Start: 1867220

End: 1868050

Strand: Direct

Name: atpB

Synonym: Noca_1757

Alternate gene names: 119715992

Gene position: 1867220-1868050 (Clockwise)

Preceding gene: 119715991

Following gene: 119715993

Centisome position: 37.45

GC content: 65.1

Gene sequence:

>831_bases
GTGACCTTCGCAGCCTCCGTGGTGCGCACCGCAGAAGGAGACGGCTTCACGCCGCCCGGCCCCCACGACTTCGACCTCCC
CGCGATCGGTGGTGGCCACGACACGTTCGAGATGTTCGGCCAGTCGTTCGTGCTGGGCGTGACGAAGCCGATGCTCCAGC
TCGTCCTCGCGGCGATCGTGCTGTTCGTCTTCTTCTTCGCGGCCGCGCGCAAGCGGGCAATGGTGCCGAGCCGGCTGCAG
TTCGTCGGCGAGGGGTTCTACGGCTTCGTGCGCAACTCGCTGGGCCGAGACATCATCGGCCACGACTTCGCGAAGTTCGT
GCCCTACCTGTTCACGCTGTTCTTCTTCATCCTGCTCAACAACGCGTTCGGGAGCATCCCGTTCATCGAGTTCCCGACGT
TCTCGCGCTCGGGCATGGTCTACGGCCTCGCGGTCCTCAGCTGGGTGATCTACAACGCGGCCGGCATCAGCAAGCACGGC
TTCGTCGGCTACCTCAAGCTCCAGACGGTGCCCGGCGGCATCCGGGGCCCGATCCTGGCGCTGCTGATCCCGCTCGAGTT
CATGTCGAACATCCTGGTCCGCCCGGTCACGCTGGCCCTGCGTCTGTTCGCCAACATGTTCGCCGGCCACCTGCTGCTGA
TCCTGTTCGCGCTCGGCGGCGAGTACATCCTCACCGAGATGTCGGTGCAGTACGCCCCGGTCGGCATCCTCGCCTGGCTG
ATGTTCGTCGCGGTCGCGTTCTTGGAGATGCTGATCCAGTTCCTGCAGGCCTACGTCTTCGTCCTCCTGAACGCCATGTA
CATCTCCGGCGCGGTCGCGGACGAGCACTGA

Upstream 100 bases:

>100_bases
GCAGTGGGGATCCTGCTCGGCGCGGGACTCGGCATCTACCTGACCTTCGCCCGGTTCAACCGCGCGCAGCCACACGAGCA
CGACACGTAGAGGAGAACCG

Downstream 100 bases:

>100_bases
TCTCCACCCAGAGTCCCACCCAGGTCTCCACCTCACCTCGAAGTAGCAAGTAACCCGAAAGGAAACTAGCCGTGATCCCA
ATGGCTATCGAAGGCTCCGC

Product: ATP synthase F0 subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6

Number of amino acids: Translated: 276; Mature: 275

Protein sequence:

>276_residues
MTFAASVVRTAEGDGFTPPGPHDFDLPAIGGGHDTFEMFGQSFVLGVTKPMLQLVLAAIVLFVFFFAAARKRAMVPSRLQ
FVGEGFYGFVRNSLGRDIIGHDFAKFVPYLFTLFFFILLNNAFGSIPFIEFPTFSRSGMVYGLAVLSWVIYNAAGISKHG
FVGYLKLQTVPGGIRGPILALLIPLEFMSNILVRPVTLALRLFANMFAGHLLLILFALGGEYILTEMSVQYAPVGILAWL
MFVAVAFLEMLIQFLQAYVFVLLNAMYISGAVADEH

Sequences:

>Translated_276_residues
MTFAASVVRTAEGDGFTPPGPHDFDLPAIGGGHDTFEMFGQSFVLGVTKPMLQLVLAAIVLFVFFFAAARKRAMVPSRLQ
FVGEGFYGFVRNSLGRDIIGHDFAKFVPYLFTLFFFILLNNAFGSIPFIEFPTFSRSGMVYGLAVLSWVIYNAAGISKHG
FVGYLKLQTVPGGIRGPILALLIPLEFMSNILVRPVTLALRLFANMFAGHLLLILFALGGEYILTEMSVQYAPVGILAWL
MFVAVAFLEMLIQFLQAYVFVLLNAMYISGAVADEH
>Mature_275_residues
TFAASVVRTAEGDGFTPPGPHDFDLPAIGGGHDTFEMFGQSFVLGVTKPMLQLVLAAIVLFVFFFAAARKRAMVPSRLQF
VGEGFYGFVRNSLGRDIIGHDFAKFVPYLFTLFFFILLNNAFGSIPFIEFPTFSRSGMVYGLAVLSWVIYNAAGISKHGF
VGYLKLQTVPGGIRGPILALLIPLEFMSNILVRPVTLALRLFANMFAGHLLLILFALGGEYILTEMSVQYAPVGILAWLM
FVAVAFLEMLIQFLQAYVFVLLNAMYISGAVADEH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family

Homologues:

Organism=Saccharomyces cerevisiae, GI6226527, Length=248, Percent_Identity=28.6290322580645, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATP6_NOCSJ (A1SHI5)

Other databases:

- EMBL:   CP000509
- RefSeq:   YP_922957.1
- ProteinModelPortal:   A1SHI5
- SMR:   A1SHI5
- STRING:   A1SHI5
- GeneID:   4597939
- GenomeReviews:   CP000509_GR
- KEGG:   nca:Noca_1757
- eggNOG:   COG0356
- HOGENOM:   HBG734175
- OMA:   NISPNAR
- PhylomeDB:   A1SHI5
- ProtClustDB:   CLSK2783471
- BioCyc:   NSP35761:NOCA_1757-MONOMER
- HAMAP:   MF_01393
- InterPro:   IPR000568
- InterPro:   IPR023011
- Gene3D:   G3DSA:1.20.120.220
- PANTHER:   PTHR11410
- PRINTS:   PR00123
- TIGRFAMs:   TIGR01131

Pfam domain/function: PF00119 ATP-synt_A; SSF81336 ATPase_F0_A

EC number: 3.6.3.14

Molecular weight: Translated: 30349; Mature: 30218

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1766c178)-; HASH(0x17e59574)-; HASH(0x17828c5c)-; HASH(0x174cb844)-; HASH(0x17a446f8)-; HASH(0x14390878)-; HASH(0x17819128)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFAASVVRTAEGDGFTPPGPHDFDLPAIGGGHDTFEMFGQSFVLGVTKPMLQLVLAAIV
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVFFFAAARKRAMVPSRLQFVGEGFYGFVRNSLGRDIIGHDFAKFVPYLFTLFFFILLN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
NAFGSIPFIEFPTFSRSGMVYGLAVLSWVIYNAAGISKHGFVGYLKLQTVPGGIRGPILA
HHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHH
LLIPLEFMSNILVRPVTLALRLFANMFAGHLLLILFALGGEYILTEMSVQYAPVGILAWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCHHHHHHHH
MFVAVAFLEMLIQFLQAYVFVLLNAMYISGAVADEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
TFAASVVRTAEGDGFTPPGPHDFDLPAIGGGHDTFEMFGQSFVLGVTKPMLQLVLAAIV
CHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVFFFAAARKRAMVPSRLQFVGEGFYGFVRNSLGRDIIGHDFAKFVPYLFTLFFFILLN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
NAFGSIPFIEFPTFSRSGMVYGLAVLSWVIYNAAGISKHGFVGYLKLQTVPGGIRGPILA
HHCCCCCCEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCHHHHHHH
LLIPLEFMSNILVRPVTLALRLFANMFAGHLLLILFALGGEYILTEMSVQYAPVGILAWL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHCHHHHHHHH
MFVAVAFLEMLIQFLQAYVFVLLNAMYISGAVADEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA